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The map label for this gene is aroB [H]

Identifier: 187735177

GI number: 187735177

Start: 789880

End: 791043

Strand: Direct

Name: aroB [H]

Synonym: Amuc_0671

Alternate gene names: 187735177

Gene position: 789880-791043 (Clockwise)

Preceding gene: 187735176

Following gene: 187735182

Centisome position: 29.65

GC content: 58.59

Gene sequence:

>1164_bases
ATGTCACTTCACACGCTGAATATCCGGCTTGATTTTCCCTACAGGACAGGCTTTACCCATGGAGCCTTCCGCCCGGAAAA
CGATGCTCTGGCCAGCCTGATGGAACAGAGGCCCGGAAGCCGCGTTCTCGTTCTCCTGGAAAAAGGGCTGGAACAGTTTT
ATCCGCAGCTTCCGTCAGACATTGACCGCTATTTTGAAAAAAATGCCGGGGTACTGGCCTATGCCGGCTGTTGTTCCGTT
CCGGGCGGGGAGGAAGCCAAAACAGGTTTTTCCGCATGGGAAACGGCCCTGCGCCACATTGTGGAAGCAGGCATTGACCG
CCATTCCTATATCATAGCCGTGGGCGGCGGAGCGTTTCTTGACGTAGCAGGCTTTGCCGCCGCCACCGCCCATCGCGGCA
TCCGGCTGTTGCGCATCCCCACCACCACCCTCTCCCAGGCAGACTCCGGAGTAGGTGTCAAAAACGGGATCAATTTCATG
GGCCGGAAAAACTATCTGGGCACCTTCGCCGTTGCGTGGGCCACGCTTGACGACTTCCTGTTCCTCCATTCCCAGCCCCT
CCCCCTGAAAAGAGCCGGGCTGGCGGAAGTAGTGAAAGTGGCGGTGGTGAAAGACGCCTCTTTCTTCAACTGGCTGGAAA
CGAACGCCTCCGCGCTGGCTGTATGCGAACGGGATGCTCTGGAATATGCCGTGGAGCATTCCGCTCTGCTGCACGCCTCG
CACATTGCATGCGGAGGAGACGCCTTTGAACTGGGTTCCAGCCGCCCCCTGGACTTCGGACATTGGGCCGCCCATTACAT
GGAAACCATGTCCGGCTACACGCTGGGGCACGCGGAGGCCGTTTCCGTGGGCATGTGCCTGGACATCCTTTATTCCGTCC
GGAAAGGATGGCTGCCTGCCGCGGAGGCGGAAAGAATCATCTCCGTGCTGAAAACCCTGGAACTGCCCGTATTCCACCCC
CTGCTTTCCCGCAGGACAGAAAACGGCGCCTGCGAAGTGCTGAAAGGTCTGGAGGCCTTCCGCGAACACCTCGGCGGCCA
CCTGACGGTACTGATGCTTACCGGAATAGGCCGGGGAAAAGACGTCCATGAGATAGATGCCGCTCTGATGGAGGAATGCA
TCCGGGAAATGCAGGAAGCCGCCGGATATTCCGTTCAGGAATAA

Upstream 100 bases:

>100_bases
GAAGCTGCCAAAGCGGACCGCTTCATCCAGATGAGGGCCGTTCCCGTGCTCCGCAGGGACTAGGAATCCGCGAGCCATGT
TCACTTGCAGCCCTCCTGGC

Downstream 100 bases:

>100_bases
CAGCCCTTTCCTTGCCGCCTCCCCGTCAGAAAACAGGCAGAAGCCATCTGGCGTATCACAGAGAAATACCAGCCGGACGG
CAGTATGAAAAAAACAACGA

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 386

Protein sequence:

>387_residues
MSLHTLNIRLDFPYRTGFTHGAFRPENDALASLMEQRPGSRVLVLLEKGLEQFYPQLPSDIDRYFEKNAGVLAYAGCCSV
PGGEEAKTGFSAWETALRHIVEAGIDRHSYIIAVGGGAFLDVAGFAAATAHRGIRLLRIPTTTLSQADSGVGVKNGINFM
GRKNYLGTFAVAWATLDDFLFLHSQPLPLKRAGLAEVVKVAVVKDASFFNWLETNASALAVCERDALEYAVEHSALLHAS
HIACGGDAFELGSSRPLDFGHWAAHYMETMSGYTLGHAEAVSVGMCLDILYSVRKGWLPAAEAERIISVLKTLELPVFHP
LLSRRTENGACEVLKGLEAFREHLGGHLTVLMLTGIGRGKDVHEIDAALMEECIREMQEAAGYSVQE

Sequences:

>Translated_387_residues
MSLHTLNIRLDFPYRTGFTHGAFRPENDALASLMEQRPGSRVLVLLEKGLEQFYPQLPSDIDRYFEKNAGVLAYAGCCSV
PGGEEAKTGFSAWETALRHIVEAGIDRHSYIIAVGGGAFLDVAGFAAATAHRGIRLLRIPTTTLSQADSGVGVKNGINFM
GRKNYLGTFAVAWATLDDFLFLHSQPLPLKRAGLAEVVKVAVVKDASFFNWLETNASALAVCERDALEYAVEHSALLHAS
HIACGGDAFELGSSRPLDFGHWAAHYMETMSGYTLGHAEAVSVGMCLDILYSVRKGWLPAAEAERIISVLKTLELPVFHP
LLSRRTENGACEVLKGLEAFREHLGGHLTVLMLTGIGRGKDVHEIDAALMEECIREMQEAAGYSVQE
>Mature_386_residues
SLHTLNIRLDFPYRTGFTHGAFRPENDALASLMEQRPGSRVLVLLEKGLEQFYPQLPSDIDRYFEKNAGVLAYAGCCSVP
GGEEAKTGFSAWETALRHIVEAGIDRHSYIIAVGGGAFLDVAGFAAATAHRGIRLLRIPTTTLSQADSGVGVKNGINFMG
RKNYLGTFAVAWATLDDFLFLHSQPLPLKRAGLAEVVKVAVVKDASFFNWLETNASALAVCERDALEYAVEHSALLHASH
IACGGDAFELGSSRPLDFGHWAAHYMETMSGYTLGHAEAVSVGMCLDILYSVRKGWLPAAEAERIISVLKTLELPVFHPL
LSRRTENGACEVLKGLEAFREHLGGHLTVLMLTGIGRGKDVHEIDAALMEECIREMQEAAGYSVQE

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=355, Percent_Identity=31.5492957746479, Blast_Score=142, Evalue=4e-35,
Organism=Saccharomyces cerevisiae, GI6320332, Length=371, Percent_Identity=24.7978436657682, Blast_Score=96, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 42147; Mature: 42015

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLHTLNIRLDFPYRTGFTHGAFRPENDALASLMEQRPGSRVLVLLEKGLEQFYPQLPSD
CCEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEHHHHHHHHHHHHCCCHH
IDRYFEKNAGVLAYAGCCSVPGGEEAKTGFSAWETALRHIVEAGIDRHSYIIAVGGGAFL
HHHHHHCCCCEEEEECCCCCCCCCHHHCCHHHHHHHHHHHHHHCCCCCEEEEEECCCHHH
DVAGFAAATAHRGIRLLRIPTTTLSQADSGVGVKNGINFMGRKNYLGTFAVAWATLDDFL
HHHHHHHHHHHCCEEEEEECCHHHHCCCCCCCHHCCCCCCCCCCCHHHHHHHHHHHHHHH
FLHSQPLPLKRAGLAEVVKVAVVKDASFFNWLETNASALAVCERDALEYAVEHSALLHAS
HHCCCCCCCHHCCHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
HIACGGDAFELGSSRPLDFGHWAAHYMETMSGYTLGHAEAVSVGMCLDILYSVRKGWLPA
HHCCCCCHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCH
AEAERIISVLKTLELPVFHPLLSRRTENGACEVLKGLEAFREHLGGHLTVLMLTGIGRGK
HHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCC
DVHEIDAALMEECIREMQEAAGYSVQE
CHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SLHTLNIRLDFPYRTGFTHGAFRPENDALASLMEQRPGSRVLVLLEKGLEQFYPQLPSD
CEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEHHHHHHHHHHHHCCCHH
IDRYFEKNAGVLAYAGCCSVPGGEEAKTGFSAWETALRHIVEAGIDRHSYIIAVGGGAFL
HHHHHHCCCCEEEEECCCCCCCCCHHHCCHHHHHHHHHHHHHHCCCCCEEEEEECCCHHH
DVAGFAAATAHRGIRLLRIPTTTLSQADSGVGVKNGINFMGRKNYLGTFAVAWATLDDFL
HHHHHHHHHHHCCEEEEEECCHHHHCCCCCCCHHCCCCCCCCCCCHHHHHHHHHHHHHHH
FLHSQPLPLKRAGLAEVVKVAVVKDASFFNWLETNASALAVCERDALEYAVEHSALLHAS
HHCCCCCCCHHCCHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
HIACGGDAFELGSSRPLDFGHWAAHYMETMSGYTLGHAEAVSVGMCLDILYSVRKGWLPA
HHCCCCCHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCH
AEAERIISVLKTLELPVFHPLLSRRTENGACEVLKGLEAFREHLGGHLTVLMLTGIGRGK
HHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCC
DVHEIDAALMEECIREMQEAAGYSVQE
CHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA