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The map label for this gene is kdsA [H]

Identifier: 187735182

GI number: 187735182

Start: 795777

End: 796592

Strand: Direct

Name: kdsA [H]

Synonym: Amuc_0676

Alternate gene names: 187735182

Gene position: 795777-796592 (Clockwise)

Preceding gene: 187735177

Following gene: 187735183

Centisome position: 29.87

GC content: 58.09

Gene sequence:

>816_bases
ATGTCGTTTTACATTCAATCCGTTGAAATCGGCGGCCCGCGGCCGTTCTACCTTCTGGGCCCCTGCTCTCTGGAATGCGA
ATCCTTTGTATGGGAGATGGCCCGCTCCATCAAGGCCATCGCGGAAAACCTGGATGTCCCGCTGATCTTCAAAGCTTCCT
ACGACAAGGCGAACCGCACTTCCGTCACCTCTTTTCGCGGCCCAGGCGTGCAGGAAGGCTGCCGCATTCTGTCGGAAATC
GGCAGGGAGCTGAAACTGCCCGTCGTTACGGATGTGCATACGGCCCAGGAAGCGGAAATTGCCGCCGAATACGTGGATCT
GCTCCAGGTTCCCGCTTTTTTGTGCCGCCAGACGGATCTTCTGGAAGCCTGCGCCAAGAGCGGCCGGCCCGTGAATATCA
AAAAAGGGCAGTTCCTGGCTCCGTGGGATACCGTGAACATCGGGGAAAAAATGCGCGCCTTCGGCTGTGACGAATTCATG
ATGTGCGAACGCGGCACCACCTTTGGTTATAACAATCTGGTGGTGGACATGCGCTCCCTGTACTGGATGAAACAGGAAGG
CTTTCCCGTCGTATTCGACGCCACTCACGCAGTTCAGAAACCCGGGGGATTGGGAGGAACCACGGGAGGAGACAGCGAGC
TGGCCCCCGTGCTGGCATCCGCCGCCATGGCGACGGGCAGCATTGACGGCGTGTTCATGGAGGTGCACAAAGACCCGTCC
AAAGCGCTTTCCGACGGCCCCAACCAAATTCCTCTCCACCTGCTTGAAGGAGTGCTGAAACGCCTTCAGTCCATCCACCA
GGCGGTTCAGTCATGA

Upstream 100 bases:

>100_bases
AAATAAACCTTCGCCTCCGAATCTCCGCGCGGAGGCAGGATAGCGGCTTGACCGAAAGGCCTGAAACCGTCATGATACAA
GGACATACAGGTTTTGTTTT

Downstream 100 bases:

>100_bases
TGAAATTATTGTCCACATGCTTTTTGACAGCCGCCCTGTACGGCACGGAGGCGCAAGCGGACACCAGCCTGCCCGCAGCC
ACGCCTTTTGCCGGCGTAGA

Product: 2-dehydro-3-deoxyphosphooctonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase; KDO-8-phosphate synthase; KDO 8-P synthase; KDOPS; Phospho-2-dehydro-3-deoxyoctonate aldolase [H]

Number of amino acids: Translated: 271; Mature: 270

Protein sequence:

>271_residues
MSFYIQSVEIGGPRPFYLLGPCSLECESFVWEMARSIKAIAENLDVPLIFKASYDKANRTSVTSFRGPGVQEGCRILSEI
GRELKLPVVTDVHTAQEAEIAAEYVDLLQVPAFLCRQTDLLEACAKSGRPVNIKKGQFLAPWDTVNIGEKMRAFGCDEFM
MCERGTTFGYNNLVVDMRSLYWMKQEGFPVVFDATHAVQKPGGLGGTTGGDSELAPVLASAAMATGSIDGVFMEVHKDPS
KALSDGPNQIPLHLLEGVLKRLQSIHQAVQS

Sequences:

>Translated_271_residues
MSFYIQSVEIGGPRPFYLLGPCSLECESFVWEMARSIKAIAENLDVPLIFKASYDKANRTSVTSFRGPGVQEGCRILSEI
GRELKLPVVTDVHTAQEAEIAAEYVDLLQVPAFLCRQTDLLEACAKSGRPVNIKKGQFLAPWDTVNIGEKMRAFGCDEFM
MCERGTTFGYNNLVVDMRSLYWMKQEGFPVVFDATHAVQKPGGLGGTTGGDSELAPVLASAAMATGSIDGVFMEVHKDPS
KALSDGPNQIPLHLLEGVLKRLQSIHQAVQS
>Mature_270_residues
SFYIQSVEIGGPRPFYLLGPCSLECESFVWEMARSIKAIAENLDVPLIFKASYDKANRTSVTSFRGPGVQEGCRILSEIG
RELKLPVVTDVHTAQEAEIAAEYVDLLQVPAFLCRQTDLLEACAKSGRPVNIKKGQFLAPWDTVNIGEKMRAFGCDEFMM
CERGTTFGYNNLVVDMRSLYWMKQEGFPVVFDATHAVQKPGGLGGTTGGDSELAPVLASAAMATGSIDGVFMEVHKDPSK
ALSDGPNQIPLHLLEGVLKRLQSIHQAVQS

Specific function: Synthesis Of Kdo 8-P Which Is Required For Lipid A Maturation And Cellular Growth. [C]

COG id: COG2877

COG function: function code M; 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsA family [H]

Homologues:

Organism=Escherichia coli, GI1787466, Length=269, Percent_Identity=40.8921933085502, Blast_Score=217, Evalue=7e-58,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006269 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.55 [H]

Molecular weight: Translated: 29606; Mature: 29475

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFYIQSVEIGGPRPFYLLGPCSLECESFVWEMARSIKAIAENLDVPLIFKASYDKANRT
CCEEEEEEECCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCC
SVTSFRGPGVQEGCRILSEIGRELKLPVVTDVHTAQEAEIAAEYVDLLQVPAFLCRQTDL
CCCCCCCCCHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHCHHHH
LEACAKSGRPVNIKKGQFLAPWDTVNIGEKMRAFGCDEFMMCERGTTFGYNNLVVDMRSL
HHHHHHCCCCEEECCCCEECCCCCCCHHHHHHHCCCCHHHHCCCCCCCCCCHHHHHHHHH
YWMKQEGFPVVFDATHAVQKPGGLGGTTGGDSELAPVLASAAMATGSIDGVFMEVHKDPS
HHHHCCCCCEEEECHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCHH
KALSDGPNQIPLHLLEGVLKRLQSIHQAVQS
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SFYIQSVEIGGPRPFYLLGPCSLECESFVWEMARSIKAIAENLDVPLIFKASYDKANRT
CEEEEEEECCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCC
SVTSFRGPGVQEGCRILSEIGRELKLPVVTDVHTAQEAEIAAEYVDLLQVPAFLCRQTDL
CCCCCCCCCHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHCHHHH
LEACAKSGRPVNIKKGQFLAPWDTVNIGEKMRAFGCDEFMMCERGTTFGYNNLVVDMRSL
HHHHHHCCCCEEECCCCEECCCCCCCHHHHHHHCCCCHHHHCCCCCCCCCCHHHHHHHHH
YWMKQEGFPVVFDATHAVQKPGGLGGTTGGDSELAPVLASAAMATGSIDGVFMEVHKDPS
HHHHCCCCCEEEECHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCHH
KALSDGPNQIPLHLLEGVLKRLQSIHQAVQS
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA