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The map label for this gene is degU [H]

Identifier: 186476730

GI number: 186476730

Start: 2226533

End: 2227414

Strand: Direct

Name: degU [H]

Synonym: Bphy_1975

Alternate gene names: 186476730

Gene position: 2226533-2227414 (Clockwise)

Preceding gene: 186476729

Following gene: 186476731

Centisome position: 64.0

GC content: 65.65

Gene sequence:

>882_bases
ATGCGATTTTCAGTTCTCAACTCAGACGCCGAACGCAGGGAAGGACTCAAGGCGCTCTTACGGCAAGTCGACCGGCAAGC
ACGTTTCGGCGAAGCACAGGACTGGCCACAGGCCGAGCGCACGTTGCGCCGTCTGCAGCCCGATCTGTTGCTGATCGACT
GGGAGGACTGGATGTCGCCCGCCGACGCCCGCGCGTTGCTCGTCAATCATCCGGGCCTGCCCGTCGCCGTGCTGGTCGAC
GATATCTCGCCCGCTCACGTGCGCGCGTTTGTCGAGAAAGGCGTGCTCGGCGTGATCCCGCGCTCGACCGACCCGCGCGT
GATCGTGCGCGCGCTCGAAATGGTTCTGCTGGGCGTCCATTACATTCCCGCTGGCGCACTGTCGCTCGACGGACGTGCAT
CGCCAGGCAGACGCGTGCGCCAGCTAGACGACCCACGCTCGCTCGAACTGTTCGCTACGCCGAAGCGGTCAAACCTGACG
GGCGGTCTCTCGCCGCGGCAAGAACAGATCATGCGCTGCGTACATATGGGCAGCACGAACAAAATGATCGCTCGCGCGCT
GGGCATCAGCGAGGGCACGGTGAAAATCCATCTGGCCACGATCTTCCAGCAACTCGGCGCGCCCAACCGCGCCGCCGCTG
TCGCGATCTACAACGGCTGGCTCACCGCGCAACTCGAGGTGCTGCGCAGCGGACAAAACCGCATCCCGCGTCAGGCACGC
GTTGCGCCCAACGTCGTACCGCTGCGTCAGCGAAAGCAGCGGACTTTCCGCTATCCGTTGCCCGGCAGCGACACTCCCGC
CACCCTGCCGATGGCAGCCGAAGCAACGGCGCCCTACGGCGCGAGGCGCCCGAGCGCGGAACGCGACGATGGCGCGATGT
AA

Upstream 100 bases:

>100_bases
CAGGGAATTTGTCATTATCGACACGACGGTGCATCGCTGCGCAACGACGAGAACGTAGCGCGCATCGCGCCGTCATGACC
GATCGATCAGGAGCCAACGC

Downstream 100 bases:

>100_bases
AGGTCGAAAGGAATCTGATGTCAATCGACATTAAATCATCGCTGGCATGGAATCCGCTCACACGTTTCACCGTTCAACGA
GTAATATGAAGACATGGGTT

Product: two component LuxR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MRFSVLNSDAERREGLKALLRQVDRQARFGEAQDWPQAERTLRRLQPDLLLIDWEDWMSPADARALLVNHPGLPVAVLVD
DISPAHVRAFVEKGVLGVIPRSTDPRVIVRALEMVLLGVHYIPAGALSLDGRASPGRRVRQLDDPRSLELFATPKRSNLT
GGLSPRQEQIMRCVHMGSTNKMIARALGISEGTVKIHLATIFQQLGAPNRAAAVAIYNGWLTAQLEVLRSGQNRIPRQAR
VAPNVVPLRQRKQRTFRYPLPGSDTPATLPMAAEATAPYGARRPSAERDDGAM

Sequences:

>Translated_293_residues
MRFSVLNSDAERREGLKALLRQVDRQARFGEAQDWPQAERTLRRLQPDLLLIDWEDWMSPADARALLVNHPGLPVAVLVD
DISPAHVRAFVEKGVLGVIPRSTDPRVIVRALEMVLLGVHYIPAGALSLDGRASPGRRVRQLDDPRSLELFATPKRSNLT
GGLSPRQEQIMRCVHMGSTNKMIARALGISEGTVKIHLATIFQQLGAPNRAAAVAIYNGWLTAQLEVLRSGQNRIPRQAR
VAPNVVPLRQRKQRTFRYPLPGSDTPATLPMAAEATAPYGARRPSAERDDGAM
>Mature_293_residues
MRFSVLNSDAERREGLKALLRQVDRQARFGEAQDWPQAERTLRRLQPDLLLIDWEDWMSPADARALLVNHPGLPVAVLVD
DISPAHVRAFVEKGVLGVIPRSTDPRVIVRALEMVLLGVHYIPAGALSLDGRASPGRRVRQLDDPRSLELFATPKRSNLT
GGLSPRQEQIMRCVHMGSTNKMIARALGISEGTVKIHLATIFQQLGAPNRAAAVAIYNGWLTAQLEVLRSGQNRIPRQAR
VAPNVVPLRQRKQRTFRYPLPGSDTPATLPMAAEATAPYGARRPSAERDDGAM

Specific function: Regulating factor for the production of extracellular proteases. The N-terminal region acts as an inhibitor, whereas the C-terminal region carries enhancing activity [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789937, Length=152, Percent_Identity=26.3157894736842, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 32383; Mature: 32383

Theoretical pI: Translated: 11.25; Mature: 11.25

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFSVLNSDAERREGLKALLRQVDRQARFGEAQDWPQAERTLRRLQPDLLLIDWEDWMSP
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCEEEEECHHHCCC
ADARALLVNHPGLPVAVLVDDISPAHVRAFVEKGVLGVIPRSTDPRVIVRALEMVLLGVH
CCCEEEEEECCCCEEEEEEECCCHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHH
YIPAGALSLDGRASPGRRVRQLDDPRSLELFATPKRSNLTGGLSPRQEQIMRCVHMGSTN
HCCCCCEECCCCCCCCHHHHHCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCH
KMIARALGISEGTVKIHLATIFQQLGAPNRAAAVAIYNGWLTAQLEVLRSGQNRIPRQAR
HHHHHHHCCCCCEEEEHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHCCHHCCCCHHH
VAPNVVPLRQRKQRTFRYPLPGSDTPATLPMAAEATAPYGARRPSAERDDGAM
CCCCCCCHHHHHHHCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRFSVLNSDAERREGLKALLRQVDRQARFGEAQDWPQAERTLRRLQPDLLLIDWEDWMSP
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCEEEEECHHHCCC
ADARALLVNHPGLPVAVLVDDISPAHVRAFVEKGVLGVIPRSTDPRVIVRALEMVLLGVH
CCCEEEEEECCCCEEEEEEECCCHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHH
YIPAGALSLDGRASPGRRVRQLDDPRSLELFATPKRSNLTGGLSPRQEQIMRCVHMGSTN
HCCCCCEECCCCCCCCHHHHHCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCH
KMIARALGISEGTVKIHLATIFQQLGAPNRAAAVAIYNGWLTAQLEVLRSGQNRIPRQAR
HHHHHHHCCCCCEEEEHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHCCHHCCCCHHH
VAPNVVPLRQRKQRTFRYPLPGSDTPATLPMAAEATAPYGARRPSAERDDGAM
CCCCCCCHHHHHHHCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7765823 [H]