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The map label for this gene is yghZ [H]

Identifier: 186476717

GI number: 186476717

Start: 2206435

End: 2207406

Strand: Direct

Name: yghZ [H]

Synonym: Bphy_1962

Alternate gene names: 186476717

Gene position: 2206435-2207406 (Clockwise)

Preceding gene: 186476714

Following gene: 186476718

Centisome position: 63.42

GC content: 59.67

Gene sequence:

>972_bases
ATGAACTACCGACGTCTCGGCCGTTCCGGCCTGCAAGTCAGCGAGCTGTCCATCGGCTCATGGGTGACTTACGGCAATCA
GGTGGACCGGACGGCCGCACGGGAATCGCTGGCGGCCGCGCGCGACGCGGGCGTCAATTTCTTCGACAACGCCGAGGTCT
ATGCGGGCGGCAAGTCCGAACAGATCATGGGGGAAGCGCTGAAAGAATTGAACTGGCCGCGCGTGAGCTACATCGTTTCG
ACGAAATTCTTCTGGGGCCTCAATGAGGCGCCGAACCAGTATCACACGCTGAACCGCAAGTATCTGATGAACGCGATCGA
CCACTCGCTCAAGCGTCTGCAGCTCGATTATGTTGATCTGGTGTTCTGTCATCGTCCTGATCCGTACACGCCGATCGAAG
AAACGGTGTGGGCGATGAGTGACATGATCACGCGCGGCAAGGCGCTTTACTGGGGCTCGTCCGAATGGAGCGCCGATGAA
ATTCGCGCGGCCTATGAGATTGCCGAACGTCATCATCTGCACAAGCCAGTGATGGAGCAGCCGCAATACAACCTGTTCCA
TCGCAAGCGCGTGGAGCAGGAATACCGGCGGCTTTATGAAGACATCGGCCTGGGTCTGACCACGTGGAGTCCGCTTGCCT
CCGGTCTGCTGACGGGCAAGTATCGCAACGGGGTGCCTGCCGGCAGCCGCGCGGAGCTGCAAGGCTACGACTGGCTGCGC
AAGGAACTGACCGACTCGGGCAAGAACAGCGTCGTCGGCCAGTTGGGCAATCTCGCGGACGAACTTGGCTGCACCGTTGG
GCAACTGGCGCTCGCATGGATCCTGACCAATCCGAACGTCAGCACGATCATCACTGGCGCATCGCGCGTCGAGCAGATCA
CGGAAAACATGAAGGCGAAGGACGTGGCCGAGCAGATCACGCCCGAGATCAAGGAGAAGATCGAAGCGATCGTCGGCGAC
CTTTATCAGTGA

Upstream 100 bases:

>100_bases
TGCATGAAGCGACGCGAACTACACACCCAAAGGCACGCCTCGCCGATTCGGATTAATGTGTGGGGTTCCGGCTACGACAC
CTCAGAAAAGGAGAAACTGG

Downstream 100 bases:

>100_bases
TGGCCGAGGCGCCGCGCGGCCGGGTCACTGACGCGCGCGGCCCGCGCCGCAAACAGAGTTGGCAGGTCGCGTACAATACG
CAGCCCCAACGTCTGACCGT

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MNYRRLGRSGLQVSELSIGSWVTYGNQVDRTAARESLAAARDAGVNFFDNAEVYAGGKSEQIMGEALKELNWPRVSYIVS
TKFFWGLNEAPNQYHTLNRKYLMNAIDHSLKRLQLDYVDLVFCHRPDPYTPIEETVWAMSDMITRGKALYWGSSEWSADE
IRAAYEIAERHHLHKPVMEQPQYNLFHRKRVEQEYRRLYEDIGLGLTTWSPLASGLLTGKYRNGVPAGSRAELQGYDWLR
KELTDSGKNSVVGQLGNLADELGCTVGQLALAWILTNPNVSTIITGASRVEQITENMKAKDVAEQITPEIKEKIEAIVGD
LYQ

Sequences:

>Translated_323_residues
MNYRRLGRSGLQVSELSIGSWVTYGNQVDRTAARESLAAARDAGVNFFDNAEVYAGGKSEQIMGEALKELNWPRVSYIVS
TKFFWGLNEAPNQYHTLNRKYLMNAIDHSLKRLQLDYVDLVFCHRPDPYTPIEETVWAMSDMITRGKALYWGSSEWSADE
IRAAYEIAERHHLHKPVMEQPQYNLFHRKRVEQEYRRLYEDIGLGLTTWSPLASGLLTGKYRNGVPAGSRAELQGYDWLR
KELTDSGKNSVVGQLGNLADELGCTVGQLALAWILTNPNVSTIITGASRVEQITENMKAKDVAEQITPEIKEKIEAIVGD
LYQ
>Mature_323_residues
MNYRRLGRSGLQVSELSIGSWVTYGNQVDRTAARESLAAARDAGVNFFDNAEVYAGGKSEQIMGEALKELNWPRVSYIVS
TKFFWGLNEAPNQYHTLNRKYLMNAIDHSLKRLQLDYVDLVFCHRPDPYTPIEETVWAMSDMITRGKALYWGSSEWSADE
IRAAYEIAERHHLHKPVMEQPQYNLFHRKRVEQEYRRLYEDIGLGLTTWSPLASGLLTGKYRNGVPAGSRAELQGYDWLR
KELTDSGKNSVVGQLGNLADELGCTVGQLALAWILTNPNVSTIITGASRVEQITENMKAKDVAEQITPEIKEKIEAIVGD
LYQ

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI27436969, Length=323, Percent_Identity=45.2012383900929, Blast_Score=303, Evalue=1e-82,
Organism=Homo sapiens, GI4504825, Length=321, Percent_Identity=45.1713395638629, Blast_Score=302, Evalue=3e-82,
Organism=Homo sapiens, GI27436964, Length=321, Percent_Identity=45.1713395638629, Blast_Score=296, Evalue=2e-80,
Organism=Homo sapiens, GI27436962, Length=321, Percent_Identity=45.1713395638629, Blast_Score=295, Evalue=5e-80,
Organism=Homo sapiens, GI27436966, Length=321, Percent_Identity=44.8598130841121, Blast_Score=293, Evalue=1e-79,
Organism=Homo sapiens, GI27436971, Length=323, Percent_Identity=45.5108359133127, Blast_Score=292, Evalue=3e-79,
Organism=Homo sapiens, GI41152114, Length=294, Percent_Identity=28.5714285714286, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI223718702, Length=291, Percent_Identity=26.4604810996564, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI41327764, Length=291, Percent_Identity=27.4914089347079, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1789375, Length=319, Percent_Identity=35.7366771159875, Blast_Score=173, Evalue=1e-44,
Organism=Escherichia coli, GI87081735, Length=335, Percent_Identity=35.8208955223881, Blast_Score=170, Evalue=9e-44,
Organism=Escherichia coli, GI1788070, Length=315, Percent_Identity=31.1111111111111, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1789199, Length=347, Percent_Identity=27.9538904899135, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1788081, Length=284, Percent_Identity=24.6478873239437, Blast_Score=74, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6325169, Length=331, Percent_Identity=25.3776435045317, Blast_Score=110, Evalue=4e-25,
Organism=Saccharomyces cerevisiae, GI6323998, Length=332, Percent_Identity=25.6024096385542, Blast_Score=83, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6319958, Length=298, Percent_Identity=24.496644295302, Blast_Score=76, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6319951, Length=341, Percent_Identity=23.7536656891496, Blast_Score=69, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24640980, Length=340, Percent_Identity=30.5882352941176, Blast_Score=187, Evalue=1e-47,
Organism=Drosophila melanogaster, GI45549126, Length=340, Percent_Identity=30.5882352941176, Blast_Score=186, Evalue=1e-47,
Organism=Drosophila melanogaster, GI24646155, Length=309, Percent_Identity=27.5080906148867, Blast_Score=91, Evalue=9e-19,
Organism=Drosophila melanogaster, GI24646159, Length=227, Percent_Identity=27.7533039647577, Blast_Score=88, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR005399
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 36580; Mature: 36580

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYRRLGRSGLQVSELSIGSWVTYGNQVDRTAARESLAAARDAGVNFFDNAEVYAGGKSE
CCHHHHCCCCCEEEHCCCCHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCHH
QIMGEALKELNWPRVSYIVSTKFFWGLNEAPNQYHTLNRKYLMNAIDHSLKRLQLDYVDL
HHHHHHHHHCCCCHHHHEEHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
VFCHRPDPYTPIEETVWAMSDMITRGKALYWGSSEWSADEIRAAYEIAERHHLHKPVMEQ
EEEECCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCHHHCC
PQYNLFHRKRVEQEYRRLYEDIGLGLTTWSPLASGLLTGKYRNGVPAGSRAELQGYDWLR
CCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHH
KELTDSGKNSVVGQLGNLADELGCTVGQLALAWILTNPNVSTIITGASRVEQITENMKAK
HHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHEEECCHHHHHHHHHHHHHH
DVAEQITPEIKEKIEAIVGDLYQ
HHHHHHCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNYRRLGRSGLQVSELSIGSWVTYGNQVDRTAARESLAAARDAGVNFFDNAEVYAGGKSE
CCHHHHCCCCCEEEHCCCCHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCHH
QIMGEALKELNWPRVSYIVSTKFFWGLNEAPNQYHTLNRKYLMNAIDHSLKRLQLDYVDL
HHHHHHHHHCCCCHHHHEEHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
VFCHRPDPYTPIEETVWAMSDMITRGKALYWGSSEWSADEIRAAYEIAERHHLHKPVMEQ
EEEECCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCHHHCC
PQYNLFHRKRVEQEYRRLYEDIGLGLTTWSPLASGLLTGKYRNGVPAGSRAELQGYDWLR
CCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHH
KELTDSGKNSVVGQLGNLADELGCTVGQLALAWILTNPNVSTIITGASRVEQITENMKAK
HHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHEEECCHHHHHHHHHHHHHH
DVAEQITPEIKEKIEAIVGDLYQ
HHHHHHCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]