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The map label for this gene is aspC [H]

Identifier: 186476714

GI number: 186476714

Start: 2202837

End: 2204036

Strand: Direct

Name: aspC [H]

Synonym: Bphy_1959

Alternate gene names: 186476714

Gene position: 2202837-2204036 (Clockwise)

Preceding gene: 186476707

Following gene: 186476717

Centisome position: 63.31

GC content: 63.67

Gene sequence:

>1200_bases
ATGTCTCTGTTCTCCGCTGTCGAACTCGCTCCCCGCGACCCGATTCTGGGCCTGAACGAAGCTTTCAACGCCGATGCGCG
CACCACCAAGGTCAATCTGGGCGTGGGCGTGTACACCAATGAGGAAGGCAAGATTCCTCTGCTACGCGCGGTTCGCGAAG
CAGAAAAGGCACGCATCGAAGCAGCGCTGCCGCGCGGCTATCTGCCCATCGAAGGTATCGCCGTCTACGACGCAGCGGTG
CAGAAGCTGCTGCTCGGCAACGATTCGCCGCTGATCGCCGCGGGCCGCGTCGTCACGGCGCAAGCGCTAGGCGGCACGGG
CGCGCTGAAGATCGGCGCGGACTTCCTGAAGCGCGTCAATCCGGCATCGAAGGTCGCGATCAGCGATCCGAGCTGGGAAA
ACCACCGCGCGCTGTTCGAAAGCGCGGGTTTCGAGGTCGTCTCGTACCCGTACTACGATGCGGCGACGCATGGCGTGAAC
TTCGAAGGCATGCTGTCGGCGCTCAACAGCTACGCGCCGGGCACGGTCGTCGTGCTGCACGCGTGCTGCCACAATCCGAC
GGGTGTCGATCTGACGGTCGACCAGTGGAAGCAGGTGGTCGCGGTCGTGAAGGCGCGCGAACTGGTGCCGTTCCTCGACA
TCGCGTATCAGGGCTTCGGCGACGGCATCGATGCCGACGCAGCGGCTGTGCGCCTTTTCGCGCAATCGGAACTGAACGTG
TTCGTGTCGTCGTCGTTCTCGAAGTCGTTCTCTCTGTATGGCGAGCGCGTCGGCGCGCTGTCGATCATTACGGGCAGCAA
GGAAGAGGCCGCTCGCGTGCTGTCCCAACTCAAGCGCGTGATCCGCACCAACTACTCGAACCCGCCGACGCACGGCGGCG
CCGTCGTCGCAGCCGTACTCGCATCGCCGGAATTGCGCGCGACGTGGGAAACGGAACTGGGCGAAATGCGCGATCGCATC
CGCGCCATGCGTCATGGTCTCGTCGAACGTTTGAAGGCGGCGGGCATCGACCGTGACTTCAGCTTCGTCAACGCACAACG
CGGCATGTTCTCGTACTCGGGTCTGACGGCGCCTCAAGTTGACCGTCTGCGTGAAGAGTTCGGCATCTACGCCGTCAGCA
CGGGCCGCATCTGCGTGGCTGCGCTGAACACGCGCAACCTTGACGTCGTCGCGAACGCCGTTGCCGCTGTGTTGAAGTAA

Upstream 100 bases:

>100_bases
CAGTTGTTCAGCCGCCAGGTCCAAACACGGTCGCAGCAAGGCGCATGCGGTTCCTAGCAGCATCCGAAGTCGTCCCTCTT
TTCACTACTGCCGAATCATC

Downstream 100 bases:

>100_bases
CGTTTGTCTGCATGACGGCGTGAGTCGCTGTCTCTGCTGGAACGAAGAAGGCGCTCCTTATGAGCGCCTTTTTTCGTGCT
GCGCAGACAACCATCGGCCC

Product: aromatic amino acid aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 399; Mature: 398

Protein sequence:

>399_residues
MSLFSAVELAPRDPILGLNEAFNADARTTKVNLGVGVYTNEEGKIPLLRAVREAEKARIEAALPRGYLPIEGIAVYDAAV
QKLLLGNDSPLIAAGRVVTAQALGGTGALKIGADFLKRVNPASKVAISDPSWENHRALFESAGFEVVSYPYYDAATHGVN
FEGMLSALNSYAPGTVVVLHACCHNPTGVDLTVDQWKQVVAVVKARELVPFLDIAYQGFGDGIDADAAAVRLFAQSELNV
FVSSSFSKSFSLYGERVGALSIITGSKEEAARVLSQLKRVIRTNYSNPPTHGGAVVAAVLASPELRATWETELGEMRDRI
RAMRHGLVERLKAAGIDRDFSFVNAQRGMFSYSGLTAPQVDRLREEFGIYAVSTGRICVAALNTRNLDVVANAVAAVLK

Sequences:

>Translated_399_residues
MSLFSAVELAPRDPILGLNEAFNADARTTKVNLGVGVYTNEEGKIPLLRAVREAEKARIEAALPRGYLPIEGIAVYDAAV
QKLLLGNDSPLIAAGRVVTAQALGGTGALKIGADFLKRVNPASKVAISDPSWENHRALFESAGFEVVSYPYYDAATHGVN
FEGMLSALNSYAPGTVVVLHACCHNPTGVDLTVDQWKQVVAVVKARELVPFLDIAYQGFGDGIDADAAAVRLFAQSELNV
FVSSSFSKSFSLYGERVGALSIITGSKEEAARVLSQLKRVIRTNYSNPPTHGGAVVAAVLASPELRATWETELGEMRDRI
RAMRHGLVERLKAAGIDRDFSFVNAQRGMFSYSGLTAPQVDRLREEFGIYAVSTGRICVAALNTRNLDVVANAVAAVLK
>Mature_398_residues
SLFSAVELAPRDPILGLNEAFNADARTTKVNLGVGVYTNEEGKIPLLRAVREAEKARIEAALPRGYLPIEGIAVYDAAVQ
KLLLGNDSPLIAAGRVVTAQALGGTGALKIGADFLKRVNPASKVAISDPSWENHRALFESAGFEVVSYPYYDAATHGVNF
EGMLSALNSYAPGTVVVLHACCHNPTGVDLTVDQWKQVVAVVKARELVPFLDIAYQGFGDGIDADAAAVRLFAQSELNVF
VSSSFSKSFSLYGERVGALSIITGSKEEAARVLSQLKRVIRTNYSNPPTHGGAVVAAVLASPELRATWETELGEMRDRIR
AMRHGLVERLKAAGIDRDFSFVNAQRGMFSYSGLTAPQVDRLREEFGIYAVSTGRICVAALNTRNLDVVANAVAAVLK

Specific function: Biosynthesis of Phe, Tyr, Asp and Leu. [C]

COG id: COG1448

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI73486658, Length=399, Percent_Identity=44.8621553884712, Blast_Score=347, Evalue=1e-95,
Organism=Homo sapiens, GI4504067, Length=401, Percent_Identity=42.643391521197, Blast_Score=322, Evalue=5e-88,
Organism=Homo sapiens, GI117414139, Length=399, Percent_Identity=26.5664160401003, Blast_Score=162, Evalue=5e-40,
Organism=Escherichia coli, GI1790488, Length=399, Percent_Identity=55.6390977443609, Blast_Score=442, Evalue=1e-125,
Organism=Escherichia coli, GI1787159, Length=396, Percent_Identity=47.4747474747475, Blast_Score=400, Evalue=1e-113,
Organism=Caenorhabditis elegans, GI71981858, Length=400, Percent_Identity=42.75, Blast_Score=351, Evalue=4e-97,
Organism=Caenorhabditis elegans, GI25147133, Length=399, Percent_Identity=42.3558897243108, Blast_Score=335, Evalue=4e-92,
Organism=Caenorhabditis elegans, GI17569539, Length=402, Percent_Identity=39.5522388059701, Blast_Score=298, Evalue=4e-81,
Organism=Caenorhabditis elegans, GI17569537, Length=398, Percent_Identity=33.9195979899498, Blast_Score=213, Evalue=1e-55,
Organism=Caenorhabditis elegans, GI25147136, Length=213, Percent_Identity=41.7840375586854, Blast_Score=182, Evalue=3e-46,
Organism=Caenorhabditis elegans, GI17550384, Length=270, Percent_Identity=34.8148148148148, Blast_Score=176, Evalue=2e-44,
Organism=Saccharomyces cerevisiae, GI6323055, Length=407, Percent_Identity=38.3292383292383, Blast_Score=301, Evalue=2e-82,
Organism=Saccharomyces cerevisiae, GI6322743, Length=436, Percent_Identity=32.3394495412844, Blast_Score=239, Evalue=6e-64,
Organism=Drosophila melanogaster, GI24580972, Length=400, Percent_Identity=41.5, Blast_Score=323, Evalue=1e-88,
Organism=Drosophila melanogaster, GI24580970, Length=400, Percent_Identity=41.5, Blast_Score=323, Evalue=1e-88,
Organism=Drosophila melanogaster, GI19920542, Length=393, Percent_Identity=41.4758269720102, Blast_Score=317, Evalue=1e-86,
Organism=Drosophila melanogaster, GI19922362, Length=401, Percent_Identity=40.1496259351621, Blast_Score=308, Evalue=6e-84,
Organism=Drosophila melanogaster, GI24654046, Length=401, Percent_Identity=40.1496259351621, Blast_Score=307, Evalue=7e-84,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000796
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 42796; Mature: 42665

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLFSAVELAPRDPILGLNEAFNADARTTKVNLGVGVYTNEEGKIPLLRAVREAEKARIE
CCCHHHHHCCCCCCCCCCHHHCCCCCCEEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHH
AALPRGYLPIEGIAVYDAAVQKLLLGNDSPLIAAGRVVTAQALGGTGALKIGADFLKRVN
HHCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCEEEEECCCCCCEEHHHHHHHHHCC
PASKVAISDPSWENHRALFESAGFEVVSYPYYDAATHGVNFEGMLSALNSYAPGTVVVLH
CCCEEEECCCCCCHHHHHHHHCCCEEEECCCCCCHHCCCCHHHHHHHHHCCCCCHHEEEE
ACCHNPTGVDLTVDQWKQVVAVVKARELVPFLDIAYQGFGDGIDADAAAVRLFAQSELNV
HHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCEE
FVSSSFSKSFSLYGERVGALSIITGSKEEAARVLSQLKRVIRTNYSNPPTHGGAVVAAVL
EEECCCHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
ASPELRATWETELGEMRDRIRAMRHGLVERLKAAGIDRDFSFVNAQRGMFSYSGLTAPQV
CCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCEECCCCCCHHH
DRLREEFGIYAVSTGRICVAALNTRNLDVVANAVAAVLK
HHHHHHHCEEEEECCCEEEEEECCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SLFSAVELAPRDPILGLNEAFNADARTTKVNLGVGVYTNEEGKIPLLRAVREAEKARIE
CCHHHHHCCCCCCCCCCHHHCCCCCCEEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHH
AALPRGYLPIEGIAVYDAAVQKLLLGNDSPLIAAGRVVTAQALGGTGALKIGADFLKRVN
HHCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCEEEEECCCCCCEEHHHHHHHHHCC
PASKVAISDPSWENHRALFESAGFEVVSYPYYDAATHGVNFEGMLSALNSYAPGTVVVLH
CCCEEEECCCCCCHHHHHHHHCCCEEEECCCCCCHHCCCCHHHHHHHHHCCCCCHHEEEE
ACCHNPTGVDLTVDQWKQVVAVVKARELVPFLDIAYQGFGDGIDADAAAVRLFAQSELNV
HHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCEE
FVSSSFSKSFSLYGERVGALSIITGSKEEAARVLSQLKRVIRTNYSNPPTHGGAVVAAVL
EEECCCHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
ASPELRATWETELGEMRDRIRAMRHGLVERLKAAGIDRDFSFVNAQRGMFSYSGLTAPQV
CCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCEECCCCCCHHH
DRLREEFGIYAVSTGRICVAALNTRNLDVVANAVAAVLK
HHHHHHHCEEEEECCCEEEEEECCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043; 8808952 [H]