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The map label for this gene is kdgK [H]

Identifier: 186476012

GI number: 186476012

Start: 1403574

End: 1404536

Strand: Reverse

Name: kdgK [H]

Synonym: Bphy_1253

Alternate gene names: 186476012

Gene position: 1404536-1403574 (Counterclockwise)

Preceding gene: 186476013

Following gene: 186476011

Centisome position: 40.37

GC content: 66.25

Gene sequence:

>963_bases
ATGCATCCGACACTCGATGTCATCACCTACGGCGAAGCGATGGCGATGTTCGTCGCGGCCGAAACGGGCCCGCTCGCGAG
CGTCGGCCAGTTCACGAAACGTGTTGCGGGCGCCGACCTCAACGTGGCGATCGGCCTGGCGCGGCTCGGCTTCAAGGTGG
GCTGGATGAGCCGCGTCGGCGCCGATTCGTTCGGTCAGTATGTGCGCGACACGCTCGCGCAGGAAGGCATCGATCAGGCG
TGCGTGACGACGGATGCACGCTATTCGACGGGCTTCCAGCTGAAGTCGAAGAACGACGACGGCAGCGATCCCGCCGTCGA
GTATTTCCGCAAGGGTTCGGCGGCGAGTCATCTGTCGCTGGTCGATTACGTGGACACCTACGTGCTTGCCGCGCGCCATC
TGCATCTGACGGGCGTCGCGCCCGCGATTTCGCGCAGTTCGCGCGAACTCGCGTTCCATATGGCGCGCGAAATGCGGCAG
GCAGGCAAGACGATCTCGTTCGATCCGAACCTGCGCCCGACGCTTTGGCCATCGCGCGAAGCGATGGCGACGGCACTGAA
TGAACTGGCGACGTTCGCCGACTGGGTGCTGCCGGGCATCGGCGAGGGCGAGATTCTGACGGGCTACACGAAGGCCGACG
ACATTGCGCAGTTTTATCTCGATCGCGGCGCGAAGGGCGTCGTCGTGAAGCTTGGCGCTCGAGGCGCGTATTACCGCACG
GCGGCAGACTCCGGCGTCGTCGCGGCACAGCCTGTCGAACGGGTTGTCGATACCGTCGGGGCGGGCGATGGCTTTGCCGT
CGGTGTGGTCAGCGCGCTGCTCGAAGGGCGTACGCTGCCGCAGGCGGTGGTGCGCGGCAACCGCATCGGCGCGCTCGCGA
TCCAGGTGATCGGCGATTCCGAAGGGCTGCCGACGCGCGCCGAACTGGACGCGCTCGAAAGCGATGCCGCACTGGCCGCG
TAG

Upstream 100 bases:

>100_bases
TTCGACGCCACGCGCCTCGCCGCCGACGCGTCGCACTACGTCGCATGGCTCGCGTCCGCCTGAGCGCCGCAAGCGTCGAC
TGAATCACGAAGGAGAAGGC

Downstream 100 bases:

>100_bases
CAGGCCCCCGATTTCAGCATTCAGCAGTACAGGACGAGAACAACAAGATGCACGGCCGCACGCTTGCAACGACGCAAAAC
GCGCGGCTCGACAGCACATC

Product: ribokinase-like domain-containing protein

Products: NA

Alternate protein names: 2-keto-3-deoxygluconokinase; 3-deoxy-2-oxo-D-gluconate kinase; KDG kinase [H]

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MHPTLDVITYGEAMAMFVAAETGPLASVGQFTKRVAGADLNVAIGLARLGFKVGWMSRVGADSFGQYVRDTLAQEGIDQA
CVTTDARYSTGFQLKSKNDDGSDPAVEYFRKGSAASHLSLVDYVDTYVLAARHLHLTGVAPAISRSSRELAFHMAREMRQ
AGKTISFDPNLRPTLWPSREAMATALNELATFADWVLPGIGEGEILTGYTKADDIAQFYLDRGAKGVVVKLGARGAYYRT
AADSGVVAAQPVERVVDTVGAGDGFAVGVVSALLEGRTLPQAVVRGNRIGALAIQVIGDSEGLPTRAELDALESDAALAA

Sequences:

>Translated_320_residues
MHPTLDVITYGEAMAMFVAAETGPLASVGQFTKRVAGADLNVAIGLARLGFKVGWMSRVGADSFGQYVRDTLAQEGIDQA
CVTTDARYSTGFQLKSKNDDGSDPAVEYFRKGSAASHLSLVDYVDTYVLAARHLHLTGVAPAISRSSRELAFHMAREMRQ
AGKTISFDPNLRPTLWPSREAMATALNELATFADWVLPGIGEGEILTGYTKADDIAQFYLDRGAKGVVVKLGARGAYYRT
AADSGVVAAQPVERVVDTVGAGDGFAVGVVSALLEGRTLPQAVVRGNRIGALAIQVIGDSEGLPTRAELDALESDAALAA
>Mature_320_residues
MHPTLDVITYGEAMAMFVAAETGPLASVGQFTKRVAGADLNVAIGLARLGFKVGWMSRVGADSFGQYVRDTLAQEGIDQA
CVTTDARYSTGFQLKSKNDDGSDPAVEYFRKGSAASHLSLVDYVDTYVLAARHLHLTGVAPAISRSSRELAFHMAREMRQ
AGKTISFDPNLRPTLWPSREAMATALNELATFADWVLPGIGEGEILTGYTKADDIAQFYLDRGAKGVVVKLGARGAYYRT
AADSGVVAAQPVERVVDTVGAGDGFAVGVVSALLEGRTLPQAVVRGNRIGALAIQVIGDSEGLPTRAELDALESDAALAA

Specific function: Unknown

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Escherichia coli, GI87081971, Length=320, Percent_Identity=27.5, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI87082281, Length=288, Percent_Identity=27.4305555555556, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1790193, Length=281, Percent_Identity=27.7580071174377, Blast_Score=76, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.45 [H]

Molecular weight: Translated: 33813; Mature: 33813

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHPTLDVITYGEAMAMFVAAETGPLASVGQFTKRVAGADLNVAIGLARLGFKVGWMSRVG
CCCCCEEEECCHHHEEEEEECCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCC
ADSFGQYVRDTLAQEGIDQACVTTDARYSTGFQLKSKNDDGSDPAVEYFRKGSAASHLSL
HHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCEEEECCCCCCCCHHHHHHHCCCCHHHHHH
VDYVDTYVLAARHLHLTGVAPAISRSSRELAFHMAREMRQAGKTISFDPNLRPTLWPSRE
HHHHHHHHHHHHHHEEECCCHHHHCCHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCHH
AMATALNELATFADWVLPGIGEGEILTGYTKADDIAQFYLDRGAKGVVVKLGARGAYYRT
HHHHHHHHHHHHHHHHCCCCCCCCEEECCCCHHHHHHHHHHCCCCEEEEEECCCCCEEEE
AADSGVVAAQPVERVVDTVGAGDGFAVGVVSALLEGRTLPQAVVRGNRIGALAIQVIGDS
CCCCCCEEHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHCCCCEEEEEEEEEECC
EGLPTRAELDALESDAALAA
CCCCCHHHHHHHHCCCCCCC
>Mature Secondary Structure
MHPTLDVITYGEAMAMFVAAETGPLASVGQFTKRVAGADLNVAIGLARLGFKVGWMSRVG
CCCCCEEEECCHHHEEEEEECCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCC
ADSFGQYVRDTLAQEGIDQACVTTDARYSTGFQLKSKNDDGSDPAVEYFRKGSAASHLSL
HHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCEEEECCCCCCCCHHHHHHHCCCCHHHHHH
VDYVDTYVLAARHLHLTGVAPAISRSSRELAFHMAREMRQAGKTISFDPNLRPTLWPSRE
HHHHHHHHHHHHHHEEECCCHHHHCCHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCHH
AMATALNELATFADWVLPGIGEGEILTGYTKADDIAQFYLDRGAKGVVVKLGARGAYYRT
HHHHHHHHHHHHHHHHCCCCCCCCEEECCCCHHHHHHHHHHCCCCEEEEEECCCCCEEEE
AADSGVVAAQPVERVVDTVGAGDGFAVGVVSALLEGRTLPQAVVRGNRIGALAIQVIGDS
CCCCCCEEHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHCCCCEEEEEEEEEECC
EGLPTRAELDALESDAALAA
CCCCCHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]