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The map label for this gene is kdgR [H]

Identifier: 186476009

GI number: 186476009

Start: 1400125

End: 1401195

Strand: Reverse

Name: kdgR [H]

Synonym: Bphy_1250

Alternate gene names: 186476009

Gene position: 1401195-1400125 (Counterclockwise)

Preceding gene: 186476010

Following gene: 186476008

Centisome position: 40.27

GC content: 66.76

Gene sequence:

>1071_bases
ATGAGTACGCCGGGTTCAGGCGCACCGCGCCGCGCCACGATCAGCGACGTCGCGCGCGAGGCGGGCACGGGCAAGACGAG
CATCTCGCGCTATCTGAACGGGGAACTCAGCGTGTTGTCGCCGCAACTGCGCGCGCGCATCGAGGCGGCGATCGAGCGGC
TCGACTATCAGCCGAATCAGATGGCGCGCGGCCTCAAGCGCGGACGCAACCGGCTGATCGGCATGCTGGTCGCCGATCTG
ACCAATCCCTATTCTGTCGAAGTGCTGCAAGGCGTCGAGGCCGCGTGCCACGCGCTCGGCTACATGCCCCTCATCTGCCA
CGCAGCGAACGAAGTCGACATGGAGCGGCGCTTCCTGCAACTGCTGACCACGTATCGCGTCGAAGGCGTGATCGTCAACG
CGCTCGGCGTCAGCGAAGAAACGCTGCGGCCCGTGGGCGACGGCGGGATTCCGGCCGTGCTGGTTGACCGCAGTGTGGAC
GGGCTCGTGACCGATATGGTGGGCCTCGACAACGAAGGCGCGACGACGCTCGCGACGCGGCATCTCGTCGAGCGCGGTTT
CGAGCATGTGTGGTTCGTCGTCCAGCCGTTCGAACACATCAGTTCGCGGCGTCAGCGCGAAGCCGCGTTTCATCGGGCGC
TCGAACAATATCCGCAGGTGAGCGGGCGGACCGTCGTGCTCGAGCTCGGCGACGCGGACGAACTCGCGCAAACCTTGAGC
GGGCTCGATGCCGAACTCGATGCGGCGATTGCGGCGCATGAACAACGCGAAGGGGCAGGGCGCGCGCCGCACGTCGCGCT
GTTCGCGGCCAATGGCCCCGTTGCGCTGGCCCTCGCCCGGCATCTGAACCAACGGCATGGCCCGGACTGGCAGAAGCGCG
TGGCGCTGTTGTCGATCGACGACCCGGAATGGGCCGAGCTTGCCGGCATCACGACGATACGTCAGCCGACTTACGACATC
GGCTATCGGGCCGTCGAATTTCTGCATCAGCGCATCGACGGCGAGCAGGCCAGCGCGCGCGACTGTCTGCTGCCGGGCGT
GCTGATCGAGCGGGCATCGACGATGCGTTGA

Upstream 100 bases:

>100_bases
AGACGCGCCACGCGATGGCGCGTTGCGCGGCGGAGAATCTGGTCGGCGCACTCGACGGCACGCTGAAGATCAACATCGTC
AACCGCGACGTCCTTTCGCC

Downstream 100 bases:

>100_bases
GCGAACGTTGATCGACCTGCATTGCGGCGTGCGCTTACAATGCGCGGCGAGTTCAGCCTTTCGCCCTGTTGACGCCCATG
TCCCGTCTACCTGTTTCTCC

Product: LacI family transcription regulator

Products: NA

Alternate protein names: Kdg operon repressor [H]

Number of amino acids: Translated: 356; Mature: 355

Protein sequence:

>356_residues
MSTPGSGAPRRATISDVAREAGTGKTSISRYLNGELSVLSPQLRARIEAAIERLDYQPNQMARGLKRGRNRLIGMLVADL
TNPYSVEVLQGVEAACHALGYMPLICHAANEVDMERRFLQLLTTYRVEGVIVNALGVSEETLRPVGDGGIPAVLVDRSVD
GLVTDMVGLDNEGATTLATRHLVERGFEHVWFVVQPFEHISSRRQREAAFHRALEQYPQVSGRTVVLELGDADELAQTLS
GLDAELDAAIAAHEQREGAGRAPHVALFAANGPVALALARHLNQRHGPDWQKRVALLSIDDPEWAELAGITTIRQPTYDI
GYRAVEFLHQRIDGEQASARDCLLPGVLIERASTMR

Sequences:

>Translated_356_residues
MSTPGSGAPRRATISDVAREAGTGKTSISRYLNGELSVLSPQLRARIEAAIERLDYQPNQMARGLKRGRNRLIGMLVADL
TNPYSVEVLQGVEAACHALGYMPLICHAANEVDMERRFLQLLTTYRVEGVIVNALGVSEETLRPVGDGGIPAVLVDRSVD
GLVTDMVGLDNEGATTLATRHLVERGFEHVWFVVQPFEHISSRRQREAAFHRALEQYPQVSGRTVVLELGDADELAQTLS
GLDAELDAAIAAHEQREGAGRAPHVALFAANGPVALALARHLNQRHGPDWQKRVALLSIDDPEWAELAGITTIRQPTYDI
GYRAVEFLHQRIDGEQASARDCLLPGVLIERASTMR
>Mature_355_residues
STPGSGAPRRATISDVAREAGTGKTSISRYLNGELSVLSPQLRARIEAAIERLDYQPNQMARGLKRGRNRLIGMLVADLT
NPYSVEVLQGVEAACHALGYMPLICHAANEVDMERRFLQLLTTYRVEGVIVNALGVSEETLRPVGDGGIPAVLVDRSVDG
LVTDMVGLDNEGATTLATRHLVERGFEHVWFVVQPFEHISSRRQREAAFHRALEQYPQVSGRTVVLELGDADELAQTLSG
LDAELDAAIAAHEQREGAGRAPHVALFAANGPVALALARHLNQRHGPDWQKRVALLSIDDPEWAELAGITTIRQPTYDIG
YRAVEFLHQRIDGEQASARDCLLPGVLIERASTMR

Specific function: Transcriptional repressor of the kdg operon for pectin utilization [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790194, Length=355, Percent_Identity=27.887323943662, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1790369, Length=353, Percent_Identity=26.3456090651558, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI48994940, Length=184, Percent_Identity=31.5217391304348, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI1787948, Length=351, Percent_Identity=27.6353276353276, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1789202, Length=223, Percent_Identity=26.9058295964126, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1787906, Length=350, Percent_Identity=25.4285714285714, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1788474, Length=204, Percent_Identity=28.4313725490196, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1786540, Length=350, Percent_Identity=25.4285714285714, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1790689, Length=212, Percent_Identity=26.8867924528302, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1787580, Length=200, Percent_Identity=28, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1786268, Length=169, Percent_Identity=28.9940828402367, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1790715, Length=181, Percent_Identity=27.0718232044199, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012310
- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 38928; Mature: 38796

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTPGSGAPRRATISDVAREAGTGKTSISRYLNGELSVLSPQLRARIEAAIERLDYQPNQ
CCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHCCCHHH
MARGLKRGRNRLIGMLVADLTNPYSVEVLQGVEAACHALGYMPLICHAANEVDMERRFLQ
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHH
LLTTYRVEGVIVNALGVSEETLRPVGDGGIPAVLVDRSVDGLVTDMVGLDNEGATTLATR
HHHHHHHCEEEEEECCCCHHHHCCCCCCCCCEEEECCCCHHHHHHHHCCCCCCCHHHHHH
HLVERGFEHVWFVVQPFEHISSRRQREAAFHRALEQYPQVSGRTVVLELGDADELAQTLS
HHHHHCHHHEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHH
GLDAELDAAIAAHEQREGAGRAPHVALFAANGPVALALARHLNQRHGPDWQKRVALLSID
CCCHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCHHHCEEEEECC
DPEWAELAGITTIRQPTYDIGYRAVEFLHQRIDGEQASARDCLLPGVLIERASTMR
CCCHHHHHCCHHCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
STPGSGAPRRATISDVAREAGTGKTSISRYLNGELSVLSPQLRARIEAAIERLDYQPNQ
CCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHCCCHHH
MARGLKRGRNRLIGMLVADLTNPYSVEVLQGVEAACHALGYMPLICHAANEVDMERRFLQ
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHH
LLTTYRVEGVIVNALGVSEETLRPVGDGGIPAVLVDRSVDGLVTDMVGLDNEGATTLATR
HHHHHHHCEEEEEECCCCHHHHCCCCCCCCCEEEECCCCHHHHHHHHCCCCCCCHHHHHH
HLVERGFEHVWFVVQPFEHISSRRQREAAFHRALEQYPQVSGRTVVLELGDADELAQTLS
HHHHHCHHHEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHH
GLDAELDAAIAAHEQREGAGRAPHVALFAANGPVALALARHLNQRHGPDWQKRVALLSID
CCCHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCHHHCEEEEECC
DPEWAELAGITTIRQPTYDIGYRAVEFLHQRIDGEQASARDCLLPGVLIERASTMR
CCCHHHHHCCHHCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]