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The map label for this gene is rbsK [H]

Identifier: 186475992

GI number: 186475992

Start: 1384481

End: 1385410

Strand: Reverse

Name: rbsK [H]

Synonym: Bphy_1233

Alternate gene names: 186475992

Gene position: 1385410-1384481 (Counterclockwise)

Preceding gene: 186475993

Following gene: 186475991

Centisome position: 39.82

GC content: 72.26

Gene sequence:

>930_bases
GTGGCAACGAATGAAGCGCGCGGACACGTGACGGTGATCGGCAGTCTGAACATGGATCTCGTCGCGCGCGCGCCGCGCCT
GCCGCAGCCGGGTGAGACGCTGGCGGGCCACGCGTTCGCGCAGGTCGCGGGGGGCAAGGGCGGCAATCAGGCCGTCGCGG
CGGCCCGGCTCGGTGCGCAGGTGGCGATGCTCGGCTGCGTCGGCGCCGATGCGAACGGCGCACAGTTGCGCGCGGGCCTC
GAAGCGGAAGGCATCGATTGCGCCGCGCTCGAAACGAGCGCAGCCGCGCCGACGGGCGTCGCGCTCATCATCGTCGACGA
CGGCAGCCAGAATGCGATCGTCATCGTAGCGGGCAGCAACGGCGAGGTGGCGCCGGACACGATCTCACGCCACGAAGCGG
CGCTGGCCGCGGCGAACGTGGTGATCTGCCAGCTGGAAACGCCGCCCGCAGCCGTGCGCGCGGCGCTTGCCGTCGCGCGC
CGGCTCGGCAAGACCGTCATTCTGAACCCGGCGCCTGCCGCGGGTCCGCTGCCCGCTGACTGGCTGCCGCTGATCGATTA
TCTGATTCCGAACGAACTGGAAGCCGCGGCGTTGACGGGCCTGCCCGTGACGTCGCCGCAGGAAGCGCAGGCGGCGGCGC
GTGCACTGCGCCACGCGGGAGCCCGCAACGTGATCGTGACCATCGGCGCGCAAGGCGTCGTCGCGGCGCTCGGCGACGCC
GAGCCGCAGCATTTTGAAGCGCCGCGCGTCAAGGCCGTCGACACCACGGCGGCGGGCGACACTTTCATCGGAGGCTTGGC
GGCGCAGCTGGCATGCGGCGTCGATGTTGCTGACGCCATCCGCTTCGCGCAGCGCGCCGCGGCGATTTCGGTGACGCGCG
CGGGCGCGCAGCCCTCCATTCCCGCCCGCGCCGAAGTCGTCGGCGCCTGA

Upstream 100 bases:

>100_bases
CGCGCCGCACGGCTCAGGCGGCATAAGACACGCTCTCATCGGGCGCAAGCGGGTATCGCATGCCTGTCTGTGCCCAACAG
AAGACAGCAAGGAGGCTGCA

Downstream 100 bases:

>100_bases
TCCGTCCTCCCATCTGTTGCGCGCGGGCGATGGCCGCTCGCGCGTCGAGTTTGTAGTTTTTACAGCGTCCACGCGTCTTA
TTCTTCAGACCATATAAAAC

Product: ribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MATNEARGHVTVIGSLNMDLVARAPRLPQPGETLAGHAFAQVAGGKGGNQAVAAARLGAQVAMLGCVGADANGAQLRAGL
EAEGIDCAALETSAAAPTGVALIIVDDGSQNAIVIVAGSNGEVAPDTISRHEAALAAANVVICQLETPPAAVRAALAVAR
RLGKTVILNPAPAAGPLPADWLPLIDYLIPNELEAAALTGLPVTSPQEAQAAARALRHAGARNVIVTIGAQGVVAALGDA
EPQHFEAPRVKAVDTTAAGDTFIGGLAAQLACGVDVADAIRFAQRAAAISVTRAGAQPSIPARAEVVGA

Sequences:

>Translated_309_residues
MATNEARGHVTVIGSLNMDLVARAPRLPQPGETLAGHAFAQVAGGKGGNQAVAAARLGAQVAMLGCVGADANGAQLRAGL
EAEGIDCAALETSAAAPTGVALIIVDDGSQNAIVIVAGSNGEVAPDTISRHEAALAAANVVICQLETPPAAVRAALAVAR
RLGKTVILNPAPAAGPLPADWLPLIDYLIPNELEAAALTGLPVTSPQEAQAAARALRHAGARNVIVTIGAQGVVAALGDA
EPQHFEAPRVKAVDTTAAGDTFIGGLAAQLACGVDVADAIRFAQRAAAISVTRAGAQPSIPARAEVVGA
>Mature_308_residues
ATNEARGHVTVIGSLNMDLVARAPRLPQPGETLAGHAFAQVAGGKGGNQAVAAARLGAQVAMLGCVGADANGAQLRAGLE
AEGIDCAALETSAAAPTGVALIIVDDGSQNAIVIVAGSNGEVAPDTISRHEAALAAANVVICQLETPPAAVRAALAVARR
LGKTVILNPAPAAGPLPADWLPLIDYLIPNELEAAALTGLPVTSPQEAQAAARALRHAGARNVIVTIGAQGVVAALGDAE
PQHFEAPRVKAVDTTAAGDTFIGGLAAQLACGVDVADAIRFAQRAAAISVTRAGAQPSIPARAEVVGA

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=296, Percent_Identity=41.8918918918919, Blast_Score=199, Evalue=3e-51,
Organism=Escherichia coli, GI1790193, Length=299, Percent_Identity=42.809364548495, Blast_Score=197, Evalue=8e-52,
Organism=Escherichia coli, GI87082343, Length=292, Percent_Identity=31.1643835616438, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI87081971, Length=284, Percent_Identity=26.7605633802817, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788484, Length=291, Percent_Identity=28.8659793814433, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1788491, Length=290, Percent_Identity=23.7931034482759, Blast_Score=69, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17532905, Length=298, Percent_Identity=39.261744966443, Blast_Score=197, Evalue=4e-51,
Organism=Saccharomyces cerevisiae, GI6319884, Length=328, Percent_Identity=32.9268292682927, Blast_Score=144, Evalue=1e-35,
Organism=Drosophila melanogaster, GI20128807, Length=304, Percent_Identity=40.1315789473684, Blast_Score=171, Evalue=6e-43,
Organism=Drosophila melanogaster, GI24583886, Length=300, Percent_Identity=32.3333333333333, Blast_Score=142, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 30625; Mature: 30494

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATNEARGHVTVIGSLNMDLVARAPRLPQPGETLAGHAFAQVAGGKGGNQAVAAARLGAQ
CCCCCCCCEEEEEEECCHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHCHH
VAMLGCVGADANGAQLRAGLEAEGIDCAALETSAAAPTGVALIIVDDGSQNAIVIVAGSN
EEEEEEECCCCCCHHEECCCCCCCCEEEEECCCCCCCCCEEEEEEECCCCCEEEEEECCC
GEVAPDTISRHEAALAAANVVICQLETPPAAVRAALAVARRLGKTVILNPAPAAGPLPAD
CCCCCCHHHHHHHHHEEEEEEEEEECCCHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCH
WLPLIDYLIPNELEAAALTGLPVTSPQEAQAAARALRHAGARNVIVTIGAQGVVAALGDA
HHHHHHHHCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCEEEECCCC
EPQHFEAPRVKAVDTTAAGDTFIGGLAAQLACGVDVADAIRFAQRAAAISVTRAGAQPSI
CCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHEEEEECCCCCCC
PARAEVVGA
CCCEEEECC
>Mature Secondary Structure 
ATNEARGHVTVIGSLNMDLVARAPRLPQPGETLAGHAFAQVAGGKGGNQAVAAARLGAQ
CCCCCCCEEEEEEECCHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHCHH
VAMLGCVGADANGAQLRAGLEAEGIDCAALETSAAAPTGVALIIVDDGSQNAIVIVAGSN
EEEEEEECCCCCCHHEECCCCCCCCEEEEECCCCCCCCCEEEEEEECCCCCEEEEEECCC
GEVAPDTISRHEAALAAANVVICQLETPPAAVRAALAVARRLGKTVILNPAPAAGPLPAD
CCCCCCHHHHHHHHHEEEEEEEEEECCCHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCH
WLPLIDYLIPNELEAAALTGLPVTSPQEAQAAARALRHAGARNVIVTIGAQGVVAALGDA
HHHHHHHHCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCEEEECCCC
EPQHFEAPRVKAVDTTAAGDTFIGGLAAQLACGVDVADAIRFAQRAAAISVTRAGAQPSI
CCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHEEEEECCCCCCC
PARAEVVGA
CCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]