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The map label for this gene is aroD [H]

Identifier: 183222754

GI number: 183222754

Start: 3531433

End: 3532149

Strand: Direct

Name: aroD [H]

Synonym: LEPBI_I3412

Alternate gene names: 183222754

Gene position: 3531433-3532149 (Clockwise)

Preceding gene: 183222753

Following gene: 183222758

Centisome position: 98.1

GC content: 35.01

Gene sequence:

>717_bases
ATGCCAGATTCATACAAAATTGTTGCTTCTGTTGGTGAAGATGAACTTCGTCACTTGCAAAAAAAAGATGTGAAAGAAGT
AGATGTGATCGAAGTTCGTTTGGATTTATTTTCTAGAAACTATATCCAAAAAGAGATGAAAAAAAAGATCAAAGCACTCG
GACTACCTGTTCTTTTCACGTATCGACGTGCAGAAGATAGTAGTGTTCGTTCGTATGTAAAACTTTTTCCCGAAGATGTA
GAAGGCATCATCAAAGATTTTAATGATAATGCCAATTACTTAGATATCGAATTGAACCGAGAAGATACAATCTTTCGCAA
TTACGAGACTTTGAATTATAGAATCATCTATTCCTATCATTCTTTTAAAAAATCCATTTTGGCAAATGAAATGAACCAAT
TCATTGCCAAATCGAAACCTGTGAAAAAGAAAAATCCAATTTATAAATTTGCGATCACACCTGAAAACATCGAAGAAACT
GCGGATTTTTTAAACGATATCAAACTACTCTCCAAAACCCACACGATGATTGGAATTTGTATGGGGGAACTTGGAATCAT
TTCACGAGTTTTTGGAGACAAATTCAATTCCTCTTTCACCTATATGACATTAGGCGAACCAAAGGCTCCAGGCCAAATCT
CTGTCGATACCTTTAAAAAATTACGTGCTGATTTATTCAAAAGCCCGCAGTCGAGTAAGGAATCGAAAGAAGACTAA

Upstream 100 bases:

>100_bases
AGAGCGCCCCATTTCTGTCGCACCAGTCGTTGATGAAAATGGGATTTTTGTTGGGATGATTTCATTACACGATTTATTAC
AAAAAGGATTATAAGCTGAT

Downstream 100 bases:

>100_bases
ACTTACAAATTTGGATTGATTACTGAAACATCCCATCCTTCCCTTGGAATTTGATTTGTTTCAGTGGCTTTCATTTGAAG
GAACAGGATTCTCTTAAGGA

Product: 3-dehydroquinate dehydratase

Products: NA

Alternate protein names: 3-dehydroquinase; Type I DHQase [H]

Number of amino acids: Translated: 238; Mature: 237

Protein sequence:

>238_residues
MPDSYKIVASVGEDELRHLQKKDVKEVDVIEVRLDLFSRNYIQKEMKKKIKALGLPVLFTYRRAEDSSVRSYVKLFPEDV
EGIIKDFNDNANYLDIELNREDTIFRNYETLNYRIIYSYHSFKKSILANEMNQFIAKSKPVKKKNPIYKFAITPENIEET
ADFLNDIKLLSKTHTMIGICMGELGIISRVFGDKFNSSFTYMTLGEPKAPGQISVDTFKKLRADLFKSPQSSKESKED

Sequences:

>Translated_238_residues
MPDSYKIVASVGEDELRHLQKKDVKEVDVIEVRLDLFSRNYIQKEMKKKIKALGLPVLFTYRRAEDSSVRSYVKLFPEDV
EGIIKDFNDNANYLDIELNREDTIFRNYETLNYRIIYSYHSFKKSILANEMNQFIAKSKPVKKKNPIYKFAITPENIEET
ADFLNDIKLLSKTHTMIGICMGELGIISRVFGDKFNSSFTYMTLGEPKAPGQISVDTFKKLRADLFKSPQSSKESKED
>Mature_237_residues
PDSYKIVASVGEDELRHLQKKDVKEVDVIEVRLDLFSRNYIQKEMKKKIKALGLPVLFTYRRAEDSSVRSYVKLFPEDVE
GIIKDFNDNANYLDIELNREDTIFRNYETLNYRIIYSYHSFKKSILANEMNQFIAKSKPVKKKNPIYKFAITPENIEETA
DFLNDIKLLSKTHTMIGICMGELGIISRVFGDKFNSSFTYMTLGEPKAPGQISVDTFKKLRADLFKSPQSSKESKED

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; third step. [C]

COG id: COG0710

COG function: function code E; 3-dehydroquinate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-I 3-dehydroquinase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001381 [H]

Pfam domain/function: PF01487 DHquinase_I [H]

EC number: =4.2.1.10 [H]

Molecular weight: Translated: 27595; Mature: 27464

Theoretical pI: Translated: 9.07; Mature: 9.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDSYKIVASVGEDELRHLQKKDVKEVDVIEVRLDLFSRNYIQKEMKKKIKALGLPVLFT
CCCCEEEEEECCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
YRRAEDSSVRSYVKLFPEDVEGIIKDFNDNANYLDIELNREDTIFRNYETLNYRIIYSYH
EECCCHHHHHHHHHHCHHHHHHHHHHCCCCCCEEEEEECCCCCEEECEEEEEEEEEEEHH
SFKKSILANEMNQFIAKSKPVKKKNPIYKFAITPENIEETADFLNDIKLLSKTHTMIGIC
HHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
MGELGIISRVFGDKFNSSFTYMTLGEPKAPGQISVDTFKKLRADLFKSPQSSKESKED
HHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
PDSYKIVASVGEDELRHLQKKDVKEVDVIEVRLDLFSRNYIQKEMKKKIKALGLPVLFT
CCCEEEEEECCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
YRRAEDSSVRSYVKLFPEDVEGIIKDFNDNANYLDIELNREDTIFRNYETLNYRIIYSYH
EECCCHHHHHHHHHHCHHHHHHHHHHCCCCCCEEEEEECCCCCEEECEEEEEEEEEEEHH
SFKKSILANEMNQFIAKSKPVKKKNPIYKFAITPENIEETADFLNDIKLLSKTHTMIGIC
HHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
MGELGIISRVFGDKFNSSFTYMTLGEPKAPGQISVDTFKKLRADLFKSPQSSKESKED
HHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA