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The map label for this gene is tas [H]

Identifier: 183222673

GI number: 183222673

Start: 3437961

End: 3438977

Strand: Direct

Name: tas [H]

Synonym: LEPBI_I3328

Alternate gene names: 183222673

Gene position: 3437961-3438977 (Clockwise)

Preceding gene: 183222672

Following gene: 183222674

Centisome position: 95.51

GC content: 39.72

Gene sequence:

>1017_bases
ATGAAAAAACGAAGACTTGGCAAAACAGGAATGGTGGTTTCCGAAATTTGTATGGGAACCATGACCTTTGGATCCTCATG
TAACGAGGATGAGGCGTTTAAAATTTTAGATCGTGCATATGATGCTGGTATTGATTTTTATGATACTGCAGAAATTTACC
CTGTCCCTCCTCAAAAGTCATGGGTACACCGTACGGAAGAAATTTTTGGCAAATGGATCAAAACTAAACCAAGAGATGGA
ATCCTCATAGCATCGAAAGTGGCAGGTCCTGGCCATGGATGGTTTAGTCCACCACTGCGTGAAGGGAAAACTGCCCTTGA
CAAATACCATATCCGAAGAGCAATTGAAGGCTCCTTACAGCGATTAGGTGTTGAAACAATCGATTTGTACCAAACCCATT
GGCCTGACCATGATGTTTCTTATGATGAAACGATGGAAGCTCTCACCGAACTTAAAGAAGAAGGAAAAATTCGTTATGCT
GGTTGTTCTAATGAAACCTCTTTTGGACTCATGAAAAGTCTTTGGACATCAGACAAACATAACTTAATTCGATATGATTC
TATCCAAAACAATTTTTCGATACTCAATCGTCGGTTTGAAGATGAATTAGCTCAAGTTTGTCGAAAAGAAGGAGTGTCAT
TACTTCCTTATTCGCCTCTTGCAGGCGGAGTCCTCACTGGAAAATACAACGGTCCTACAAAACCAGAAGGGGCAAGGTTC
GTCCGTTATATGGTGGAAGGCGAAAGGCAAAAACGAATGTCCAATCGTTTTTTAAACGAACAGACATTAGCTTCTACAAA
AGAACTGATGGAAATTGCAACCAAGTATGGAATGAGTTCCACAGTTATGTCTGTTGCTTGGAGTAAACAACATGATTTTG
TTGCTTCTACTATCATTGGTGCCAATACAGTTGAGCAGTTGGAAGAATCTTTAAAAGCATCCGACTTGATTCTTTCCGAT
GAAATTTTATCAGAAATCAACCTTGTCACCAAAAAAATTCAATACCCAATGGGTTAA

Upstream 100 bases:

>100_bases
GCGATGCAAAGGGGTCCTACAAAAGCAAAAGTAAAGGATCATGTCATTGACTGGAGTGATCCTAAAAACCAATTTAAAAC
TTTTTTAATCAAAAAATAAC

Downstream 100 bases:

>100_bases
GGACGGAATTCAAATGAGTTCGAACTCGGAAAACCCAATCCCATCCAAGAGAATTAATGACGAAGTTTTAATGTCAGAAG
AAAAAAAAGTTTCTAAATGG

Product: reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MKKRRLGKTGMVVSEICMGTMTFGSSCNEDEAFKILDRAYDAGIDFYDTAEIYPVPPQKSWVHRTEEIFGKWIKTKPRDG
ILIASKVAGPGHGWFSPPLREGKTALDKYHIRRAIEGSLQRLGVETIDLYQTHWPDHDVSYDETMEALTELKEEGKIRYA
GCSNETSFGLMKSLWTSDKHNLIRYDSIQNNFSILNRRFEDELAQVCRKEGVSLLPYSPLAGGVLTGKYNGPTKPEGARF
VRYMVEGERQKRMSNRFLNEQTLASTKELMEIATKYGMSSTVMSVAWSKQHDFVASTIIGANTVEQLEESLKASDLILSD
EILSEINLVTKKIQYPMG

Sequences:

>Translated_338_residues
MKKRRLGKTGMVVSEICMGTMTFGSSCNEDEAFKILDRAYDAGIDFYDTAEIYPVPPQKSWVHRTEEIFGKWIKTKPRDG
ILIASKVAGPGHGWFSPPLREGKTALDKYHIRRAIEGSLQRLGVETIDLYQTHWPDHDVSYDETMEALTELKEEGKIRYA
GCSNETSFGLMKSLWTSDKHNLIRYDSIQNNFSILNRRFEDELAQVCRKEGVSLLPYSPLAGGVLTGKYNGPTKPEGARF
VRYMVEGERQKRMSNRFLNEQTLASTKELMEIATKYGMSSTVMSVAWSKQHDFVASTIIGANTVEQLEESLKASDLILSD
EILSEINLVTKKIQYPMG
>Mature_338_residues
MKKRRLGKTGMVVSEICMGTMTFGSSCNEDEAFKILDRAYDAGIDFYDTAEIYPVPPQKSWVHRTEEIFGKWIKTKPRDG
ILIASKVAGPGHGWFSPPLREGKTALDKYHIRRAIEGSLQRLGVETIDLYQTHWPDHDVSYDETMEALTELKEEGKIRYA
GCSNETSFGLMKSLWTSDKHNLIRYDSIQNNFSILNRRFEDELAQVCRKEGVSLLPYSPLAGGVLTGKYNGPTKPEGARF
VRYMVEGERQKRMSNRFLNEQTLASTKELMEIATKYGMSSTVMSVAWSKQHDFVASTIIGANTVEQLEESLKASDLILSD
EILSEINLVTKKIQYPMG

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436964, Length=341, Percent_Identity=29.0322580645161, Blast_Score=142, Evalue=4e-34,
Organism=Homo sapiens, GI27436962, Length=341, Percent_Identity=28.7390029325513, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI27436966, Length=341, Percent_Identity=28.7390029325513, Blast_Score=140, Evalue=1e-33,
Organism=Homo sapiens, GI27436969, Length=338, Percent_Identity=29.2899408284024, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI4504825, Length=335, Percent_Identity=29.2537313432836, Blast_Score=139, Evalue=3e-33,
Organism=Homo sapiens, GI27436971, Length=333, Percent_Identity=27.9279279279279, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI41327764, Length=215, Percent_Identity=30.6976744186047, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI223718702, Length=215, Percent_Identity=30.6976744186047, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI41152114, Length=220, Percent_Identity=30.9090909090909, Blast_Score=89, Evalue=4e-18,
Organism=Escherichia coli, GI1789199, Length=357, Percent_Identity=39.7759103641457, Blast_Score=241, Evalue=6e-65,
Organism=Escherichia coli, GI87081735, Length=335, Percent_Identity=31.044776119403, Blast_Score=147, Evalue=8e-37,
Organism=Escherichia coli, GI1789375, Length=339, Percent_Identity=29.7935103244838, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1788070, Length=333, Percent_Identity=30.03003003003, Blast_Score=124, Evalue=7e-30,
Organism=Saccharomyces cerevisiae, GI6325169, Length=343, Percent_Identity=27.6967930029155, Blast_Score=120, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6323998, Length=348, Percent_Identity=25.5747126436782, Blast_Score=111, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6319958, Length=302, Percent_Identity=24.8344370860927, Blast_Score=104, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6319951, Length=352, Percent_Identity=25.5681818181818, Blast_Score=99, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6322615, Length=267, Percent_Identity=22.8464419475655, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24646155, Length=169, Percent_Identity=31.3609467455621, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24646159, Length=171, Percent_Identity=29.8245614035088, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 38247; Mature: 38247

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKRRLGKTGMVVSEICMGTMTFGSSCNEDEAFKILDRAYDAGIDFYDTAEIYPVPPQKS
CCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEECCCCHH
WVHRTEEIFGKWIKTKPRDGILIASKVAGPGHGWFSPPLREGKTALDKYHIRRAIEGSLQ
HHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
RLGVETIDLYQTHWPDHDVSYDETMEALTELKEEGKIRYAGCSNETSFGLMKSLWTSDKH
HCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHCCCCC
NLIRYDSIQNNFSILNRRFEDELAQVCRKEGVSLLPYSPLAGGVLTGKYNGPTKPEGARF
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCEEECCCCCCCCCCHHHH
VRYMVEGERQKRMSNRFLNEQTLASTKELMEIATKYGMSSTVMSVAWSKQHDFVASTIIG
HHHHHHCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHC
ANTVEQLEESLKASDLILSDEILSEINLVTKKIQYPMG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKKRRLGKTGMVVSEICMGTMTFGSSCNEDEAFKILDRAYDAGIDFYDTAEIYPVPPQKS
CCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEECCCCHH
WVHRTEEIFGKWIKTKPRDGILIASKVAGPGHGWFSPPLREGKTALDKYHIRRAIEGSLQ
HHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
RLGVETIDLYQTHWPDHDVSYDETMEALTELKEEGKIRYAGCSNETSFGLMKSLWTSDKH
HCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHCCCCC
NLIRYDSIQNNFSILNRRFEDELAQVCRKEGVSLLPYSPLAGGVLTGKYNGPTKPEGARF
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCEEECCCCCCCCCCHHHH
VRYMVEGERQKRMSNRFLNEQTLASTKELMEIATKYGMSSTVMSVAWSKQHDFVASTIIG
HHHHHHCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHC
ANTVEQLEESLKASDLILSDEILSEINLVTKKIQYPMG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9560382; 9278503 [H]