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The map label for this gene is yycF [H]

Identifier: 183222571

GI number: 183222571

Start: 3337267

End: 3337941

Strand: Direct

Name: yycF [H]

Synonym: LEPBI_I3226

Alternate gene names: 183222571

Gene position: 3337267-3337941 (Clockwise)

Preceding gene: 183222570

Following gene: 183222572

Centisome position: 92.71

GC content: 42.37

Gene sequence:

>675_bases
ATGAAAATATTGATTGTTGATGACGAAGAAGACATTGCAGGCCTAATCCAATTCCACTTGGAAGAAGAAGGTTTCCAAAC
GGAAGTTTGCCATAATGGAATGGAAGTCCTCCCTCGTTTAGAAAAAAACCTACCTGATGGAATTATCTTAGATTTGATGT
TACCTGGCATTGGGGGTATGGACCTTTGCAAACGCATCAAAGAAAAATACCCACAAATTCCAATCCTCATGGTCACCGCC
AAAACAGGTGAAACCGATGTGGTTTTAGGTCTGGAATTGGGTGCGGATGATTACATTCGAAAACCATTCAATATCCGCGA
ATTAGTGGCTCGTGTGAGATCCGTGACTCGTCGGACCACTGACCCAAGCCAAGAAGTGCAAGGTACCATCACAACTGGAA
AAATCCAAATCAATCCTACTGCACACAAAGTATTTGTGGAAGGTACAGAGATTGATTTGACATTAATAGAATTCAAGCTA
TTACAGCTGTTTGCTGGTAATCCTGGGGTTGCCTTTTCTAGAGATAAATTATTAGATCGGATTTGGGGCAAAGATGTATT
TGTAACAGATCGCACAGTGGATGTGAACATCAAACGACTCAGAGACAAACTTCTCTCGGAAAAAGAACGACTCGAAACGA
TCCGCGGAGTCGGTTATCGATTCCGAGATGCGTAG

Upstream 100 bases:

>100_bases
GAGACATCAACCAGTTGCTTAGCAAATAAAAAGGAATCGATTTTTTGTCATCGTATTGTATTCTTTTTGTAACGAATCCC
TGTTACATTGAAATAGATTC

Downstream 100 bases:

>100_bases
TTTTTTTTCAACCCTTCTCCTTCTCAACTGGGGTCTACTACTTGTTTTATTGACCCTAGCCCTCGGCGTATTTTATATTT
ACGACTTAGTTGTACCTGCC

Product: putative response regulator receiver

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MKILIVDDEEDIAGLIQFHLEEEGFQTEVCHNGMEVLPRLEKNLPDGIILDLMLPGIGGMDLCKRIKEKYPQIPILMVTA
KTGETDVVLGLELGADDYIRKPFNIRELVARVRSVTRRTTDPSQEVQGTITTGKIQINPTAHKVFVEGTEIDLTLIEFKL
LQLFAGNPGVAFSRDKLLDRIWGKDVFVTDRTVDVNIKRLRDKLLSEKERLETIRGVGYRFRDA

Sequences:

>Translated_224_residues
MKILIVDDEEDIAGLIQFHLEEEGFQTEVCHNGMEVLPRLEKNLPDGIILDLMLPGIGGMDLCKRIKEKYPQIPILMVTA
KTGETDVVLGLELGADDYIRKPFNIRELVARVRSVTRRTTDPSQEVQGTITTGKIQINPTAHKVFVEGTEIDLTLIEFKL
LQLFAGNPGVAFSRDKLLDRIWGKDVFVTDRTVDVNIKRLRDKLLSEKERLETIRGVGYRFRDA
>Mature_224_residues
MKILIVDDEEDIAGLIQFHLEEEGFQTEVCHNGMEVLPRLEKNLPDGIILDLMLPGIGGMDLCKRIKEKYPQIPILMVTA
KTGETDVVLGLELGADDYIRKPFNIRELVARVRSVTRRTTDPSQEVQGTITTGKIQINPTAHKVFVEGTEIDLTLIEFKL
LQLFAGNPGVAFSRDKLLDRIWGKDVFVTDRTVDVNIKRLRDKLLSEKERLETIRGVGYRFRDA

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=224, Percent_Identity=41.0714285714286, Blast_Score=169, Evalue=1e-43,
Organism=Escherichia coli, GI1788394, Length=223, Percent_Identity=42.152466367713, Blast_Score=167, Evalue=7e-43,
Organism=Escherichia coli, GI1790860, Length=223, Percent_Identity=40.3587443946188, Blast_Score=164, Evalue=4e-42,
Organism=Escherichia coli, GI1789809, Length=228, Percent_Identity=39.0350877192982, Blast_Score=159, Evalue=1e-40,
Organism=Escherichia coli, GI2367329, Length=226, Percent_Identity=39.3805309734513, Blast_Score=136, Evalue=9e-34,
Organism=Escherichia coli, GI1786784, Length=221, Percent_Identity=36.1990950226244, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI87082012, Length=224, Percent_Identity=34.375, Blast_Score=117, Evalue=5e-28,
Organism=Escherichia coli, GI1789402, Length=219, Percent_Identity=33.3333333333333, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1790863, Length=229, Percent_Identity=34.4978165938865, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1790552, Length=219, Percent_Identity=32.8767123287671, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI1787375, Length=223, Percent_Identity=29.5964125560538, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1787229, Length=224, Percent_Identity=33.9285714285714, Blast_Score=110, Evalue=7e-26,
Organism=Escherichia coli, GI1786911, Length=229, Percent_Identity=32.7510917030568, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI145693140, Length=231, Percent_Identity=32.4675324675325, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1790299, Length=110, Percent_Identity=35.4545454545455, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1788550, Length=146, Percent_Identity=26.7123287671233, Blast_Score=67, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25402; Mature: 25402

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILIVDDEEDIAGLIQFHLEEEGFQTEVCHNGMEVLPRLEKNLPDGIILDLMLPGIGGM
CEEEEECCCHHHHHHHHHHHHCCCCHHHHHHCHHHHHHHHHHCCCCCEEEEECCCCCCCH
DLCKRIKEKYPQIPILMVTAKTGETDVVLGLELGADDYIRKPFNIRELVARVRSVTRRTT
HHHHHHHHHCCCCCEEEEEECCCCCEEEEEEEECCHHHHCCCCCHHHHHHHHHHHHHCCC
DPSQEVQGTITTGKIQINPTAHKVFVEGTEIDLTLIEFKLLQLFAGNPGVAFSRDKLLDR
CCHHHCEEEEEEEEEEECCCEEEEEEECCEEEEHHHHHHHHHHHCCCCCCEECHHHHHHH
IWGKDVFVTDRTVDVNIKRLRDKLLSEKERLETIRGVGYRFRDA
HCCCCEEEECCEEECHHHHHHHHHHHHHHHHHHHHHCCEEECCC
>Mature Secondary Structure
MKILIVDDEEDIAGLIQFHLEEEGFQTEVCHNGMEVLPRLEKNLPDGIILDLMLPGIGGM
CEEEEECCCHHHHHHHHHHHHCCCCHHHHHHCHHHHHHHHHHCCCCCEEEEECCCCCCCH
DLCKRIKEKYPQIPILMVTAKTGETDVVLGLELGADDYIRKPFNIRELVARVRSVTRRTT
HHHHHHHHHCCCCCEEEEEECCCCCEEEEEEEECCHHHHCCCCCHHHHHHHHHHHHHCCC
DPSQEVQGTITTGKIQINPTAHKVFVEGTEIDLTLIEFKLLQLFAGNPGVAFSRDKLLDR
CCHHHCEEEEEEEEEEECCCEEEEEEECCEEEEHHHHHHHHHHHCCCCCCEECHHHHHHH
IWGKDVFVTDRTVDVNIKRLRDKLLSEKERLETIRGVGYRFRDA
HCCCCEEEECCEEECHHHHHHHHHHHHHHHHHHHHHCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]