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The map label for this gene is resE [H]

Identifier: 183222572

GI number: 183222572

Start: 3337934

End: 3339298

Strand: Direct

Name: resE [H]

Synonym: LEPBI_I3227

Alternate gene names: 183222572

Gene position: 3337934-3339298 (Clockwise)

Preceding gene: 183222571

Following gene: 183222573

Centisome position: 92.73

GC content: 37.8

Gene sequence:

>1365_bases
ATGCGTAGTTTTTTTTCAACCCTTCTCCTTCTCAACTGGGGTCTACTACTTGTTTTATTGACCCTAGCCCTCGGCGTATT
TTATATTTACGACTTAGTTGTACCTGCCGTCCGACCACTCATTTTATTTAGTTTTGTACTCATCGCGATTTTTGGTACGT
TTTATATTTCCACAAACATTGCCATGCGAATCACAGACCCTTTGGCCACGGTTGAGAAAAAAACAAAAGAAATCAATGCT
GGAGATTTTGGTGTTGAGTTATCTTCACCTGACATTCGTGAGTTAGCAACACTTGCTTCTTCCATCAATGAAATGGCCAG
ACGTCTGAAACTCCAATTTTTGGATTTAACTGTCGAAAAAGAAAAGTTTAATTACCTCCTTCAAAACTTAAAAGAAGGTG
TCTTTGCCATTGACCGGAATCATAAATTTTTGTTTTTGAATCGTAATATTTCAGAAACTCTCATTCAAAAAAATTCTCAG
TTTAAGGAATTTGCTCCTTCCATCAAAAACAAAGAACTGCTTAGTTTTATCACCGACAAAATTTTGTCAGGTAAAGAAGG
AAAAACTGAATTTCAAGATGGTTTACATTTTTACACGGCAAGAATTTATCCCATTAAATCAGATGCCATGGTCCAACTAT
ATATTGGAGTGATTTCAGACATCACGGAAGACCGACAAAACCAATTGATTCGAGAACAATTCTTTCAAAATGCTTCCCAT
GAATTAAAAACTCCTATTACATCGATCAAAGGTTATGCGGAAACTTTAGAATACAAATTAAAACTCCAACCCGAATCCAA
TGAAAGAAAATTTTTAGACGCGATCCTCCGAAATACGGATCGTCTGATTCGAATTGTAGAAGATATGTTGACCGTTTCAA
GATTAGAAAATCACAAAACAGTTTTGAATCTAACGGATGTTTCACTTTATGAGCTCGTCAAAAATGTGTCCGAATCATTG
GGTGTACTTTATTCCCAAAAAAAACAAAATTTGGTTTTAGAAATTCCTACAGATTTAAAGGTCCGGGCAGATCGATTGTT
ACTCGAAGATTTATTGGTGAACTTAATCTCCAATGCTTCCGCTTATAGTCCCGAAGGCGCAAGTGTCATTGTAAAGGCTT
TTGCAACGAAAGAAAACAATCTGATCCAGGTGATCGACCATGGAATCGGAATTTCGGCCGAAGATGCAGAACGAATTTTT
GAACGTTTTTTCCGTGTGGATACCAATCGATCCAGAAAAGAGGGAGGAACGGGCCTCGGACTTTCCATTGTGAAACACAT
TGCAAGGCTCCATTCAGGCGAAGTGAATGTCGCTCCCAACCCGAAGGGTGGTTCCATCTTCTCCTTTGTTTTTCCTAAAA
AATAG

Upstream 100 bases:

>100_bases
GATCGCACAGTGGATGTGAACATCAAACGACTCAGAGACAAACTTCTCTCGGAAAAAGAACGACTCGAAACGATCCGCGG
AGTCGGTTATCGATTCCGAG

Downstream 100 bases:

>100_bases
ATTCTCGTAAGAGAAGTCCCTGGATAGAATGTTGGTATCCGGTAGGTAATTATGAAGTATCCTTTGGGATTTTACTCCTT
TGGCAAAAACATTGGTATCA

Product: putative histidine kinase sensor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 454; Mature: 454

Protein sequence:

>454_residues
MRSFFSTLLLLNWGLLLVLLTLALGVFYIYDLVVPAVRPLILFSFVLIAIFGTFYISTNIAMRITDPLATVEKKTKEINA
GDFGVELSSPDIRELATLASSINEMARRLKLQFLDLTVEKEKFNYLLQNLKEGVFAIDRNHKFLFLNRNISETLIQKNSQ
FKEFAPSIKNKELLSFITDKILSGKEGKTEFQDGLHFYTARIYPIKSDAMVQLYIGVISDITEDRQNQLIREQFFQNASH
ELKTPITSIKGYAETLEYKLKLQPESNERKFLDAILRNTDRLIRIVEDMLTVSRLENHKTVLNLTDVSLYELVKNVSESL
GVLYSQKKQNLVLEIPTDLKVRADRLLLEDLLVNLISNASAYSPEGASVIVKAFATKENNLIQVIDHGIGISAEDAERIF
ERFFRVDTNRSRKEGGTGLGLSIVKHIARLHSGEVNVAPNPKGGSIFSFVFPKK

Sequences:

>Translated_454_residues
MRSFFSTLLLLNWGLLLVLLTLALGVFYIYDLVVPAVRPLILFSFVLIAIFGTFYISTNIAMRITDPLATVEKKTKEINA
GDFGVELSSPDIRELATLASSINEMARRLKLQFLDLTVEKEKFNYLLQNLKEGVFAIDRNHKFLFLNRNISETLIQKNSQ
FKEFAPSIKNKELLSFITDKILSGKEGKTEFQDGLHFYTARIYPIKSDAMVQLYIGVISDITEDRQNQLIREQFFQNASH
ELKTPITSIKGYAETLEYKLKLQPESNERKFLDAILRNTDRLIRIVEDMLTVSRLENHKTVLNLTDVSLYELVKNVSESL
GVLYSQKKQNLVLEIPTDLKVRADRLLLEDLLVNLISNASAYSPEGASVIVKAFATKENNLIQVIDHGIGISAEDAERIF
ERFFRVDTNRSRKEGGTGLGLSIVKHIARLHSGEVNVAPNPKGGSIFSFVFPKK
>Mature_454_residues
MRSFFSTLLLLNWGLLLVLLTLALGVFYIYDLVVPAVRPLILFSFVLIAIFGTFYISTNIAMRITDPLATVEKKTKEINA
GDFGVELSSPDIRELATLASSINEMARRLKLQFLDLTVEKEKFNYLLQNLKEGVFAIDRNHKFLFLNRNISETLIQKNSQ
FKEFAPSIKNKELLSFITDKILSGKEGKTEFQDGLHFYTARIYPIKSDAMVQLYIGVISDITEDRQNQLIREQFFQNASH
ELKTPITSIKGYAETLEYKLKLQPESNERKFLDAILRNTDRLIRIVEDMLTVSRLENHKTVLNLTDVSLYELVKNVSESL
GVLYSQKKQNLVLEIPTDLKVRADRLLLEDLLVNLISNASAYSPEGASVIVKAFATKENNLIQVIDHGIGISAEDAERIF
ERFFRVDTNRSRKEGGTGLGLSIVKHIARLHSGEVNVAPNPKGGSIFSFVFPKK

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=238, Percent_Identity=36.5546218487395, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI1790861, Length=218, Percent_Identity=36.2385321100917, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1789149, Length=226, Percent_Identity=33.1858407079646, Blast_Score=108, Evalue=8e-25,
Organism=Escherichia coli, GI1788393, Length=266, Percent_Identity=25.9398496240602, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1786783, Length=228, Percent_Identity=31.140350877193, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788549, Length=382, Percent_Identity=24.3455497382199, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1788713, Length=280, Percent_Identity=27.8571428571429, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI145693157, Length=224, Percent_Identity=29.0178571428571, Blast_Score=96, Evalue=7e-21,
Organism=Escherichia coli, GI1790346, Length=216, Percent_Identity=31.0185185185185, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1787894, Length=244, Percent_Identity=30.7377049180328, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1788279, Length=201, Percent_Identity=30.3482587064677, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1786912, Length=230, Percent_Identity=27.8260869565217, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI48994928, Length=248, Percent_Identity=27.4193548387097, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1790551, Length=229, Percent_Identity=28.3842794759825, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI87082128, Length=226, Percent_Identity=30.0884955752212, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1789403, Length=218, Percent_Identity=32.5688073394495, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI87081816, Length=224, Percent_Identity=29.4642857142857, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1790436, Length=220, Percent_Identity=29.5454545454545, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1790300, Length=368, Percent_Identity=24.7282608695652, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 51486; Mature: 51486

Theoretical pI: Translated: 9.21; Mature: 9.21

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSFFSTLLLLNWGLLLVLLTLALGVFYIYDLVVPAVRPLILFSFVLIAIFGTFYISTNI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCE
AMRITDPLATVEKKTKEINAGDFGVELSSPDIRELATLASSINEMARRLKLQFLDLTVEK
EEEECCHHHHHHHHHHHCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECH
EKFNYLLQNLKEGVFAIDRNHKFLFLNRNISETLIQKNSQFKEFAPSIKNKELLSFITDK
HHHHHHHHHHHCCCEEEECCCEEEEEECCHHHHHHHCCCHHHHHCCCCCCHHHHHHHHHH
ILSGKEGKTEFQDGLHFYTARIYPIKSDAMVQLYIGVISDITEDRQNQLIREQFFQNASH
HHCCCCCCHHHHCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
ELKTPITSIKGYAETLEYKLKLQPESNERKFLDAILRNTDRLIRIVEDMLTVSRLENHKT
HHHCCHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
VLNLTDVSLYELVKNVSESLGVLYSQKKQNLVLEIPTDLKVRADRLLLEDLLVNLISNAS
EEEECHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCC
AYSPEGASVIVKAFATKENNLIQVIDHGIGISAEDAERIFERFFRVDTNRSRKEGGTGLG
CCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCH
LSIVKHIARLHSGEVNVAPNPKGGSIFSFVFPKK
HHHHHHHHHHCCCCEEECCCCCCCCEEEECCCCC
>Mature Secondary Structure
MRSFFSTLLLLNWGLLLVLLTLALGVFYIYDLVVPAVRPLILFSFVLIAIFGTFYISTNI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCE
AMRITDPLATVEKKTKEINAGDFGVELSSPDIRELATLASSINEMARRLKLQFLDLTVEK
EEEECCHHHHHHHHHHHCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECH
EKFNYLLQNLKEGVFAIDRNHKFLFLNRNISETLIQKNSQFKEFAPSIKNKELLSFITDK
HHHHHHHHHHHCCCEEEECCCEEEEEECCHHHHHHHCCCHHHHHCCCCCCHHHHHHHHHH
ILSGKEGKTEFQDGLHFYTARIYPIKSDAMVQLYIGVISDITEDRQNQLIREQFFQNASH
HHCCCCCCHHHHCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
ELKTPITSIKGYAETLEYKLKLQPESNERKFLDAILRNTDRLIRIVEDMLTVSRLENHKT
HHHCCHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
VLNLTDVSLYELVKNVSESLGVLYSQKKQNLVLEIPTDLKVRADRLLLEDLLVNLISNAS
EEEECHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCC
AYSPEGASVIVKAFATKENNLIQVIDHGIGISAEDAERIFERFFRVDTNRSRKEGGTGLG
CCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCH
LSIVKHIARLHSGEVNVAPNPKGGSIFSFVFPKK
HHHHHHHHHHCCCCEEECCCCCCCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]