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The map label for this gene is nodT [H]

Identifier: 183222376

GI number: 183222376

Start: 3142807

End: 3144162

Strand: Reverse

Name: nodT [H]

Synonym: LEPBI_I3030

Alternate gene names: 183222376

Gene position: 3144162-3142807 (Counterclockwise)

Preceding gene: 183222377

Following gene: 183222375

Centisome position: 87.35

GC content: 36.5

Gene sequence:

>1356_bases
GTGAAATACACTTTGATCTCTAGTATCAGTTGTTTGGTTCTGAGTCTTACACTCTTTGCGGAAACTAAAAAACCGATCCA
GCTAAAAGATTTATGGCAAAAAGCTGTTCAGTCGAATCCTGAATATTTATCCGTTAAAGCAGACTACGACAAGGCATTTT
ATGAAAATGAAAAAAGTTATGCAGGGTATTTACCAACTGTCAATGTCCTTGCTTCTGCAAGACAGTCCTCTGCCAACTTT
AGTGGATCTGGTACTGTAAACGATCCATTGATTAGCGGTGCATCAAATGGAAATCAAACACAAAACCAACAAACAAACGC
GGGTGATTCTTCTCCAACTGCAGTGAATCGATATTCGGTTGGTCTCAGTACGAATCAAAATTTATTTTCTGGATTTCGAG
ACAAAAGTGGAATCGAAAAAACAGAAGCCCTTCTCCAAGCAGCCAAACAAACATTAAATGATTCTCGTCTAAAAATCTGC
TTTGAATTAAAATCGGCGTATACGCAAGCCTTGTATGCCAAAGAACTCCATCAACTTTCCTTAAAAATCAAAGAGAGAAG
AATCAAAAATCGTGATTTGGTCAAACTACGTTATGAAGTCGGCCGTGAACATAAAGGTAGTTTTTTATTGAGTGAATCTT
TTGTAAAACAATCGGAATATGAAGTATCGTTTGCCGAACGACTCTTCCAAACTAATTGGAAGGAAATTGAAAGAGTGATC
GCTTCACCGATTGAGGTCACTTTGGATTCAACTTTGTTGTATGAACCAATTTTAGAAAAAAAATTCTCTGAAAAAGAAAA
GTCAAATTTATTAGATCTACATCCTTCGATAATGGCTGAACAGTCCAAAGTGAGAGCCGCACAAGCAAATATTGGCGTGG
CGGAGGCTGGTTTTTATCCAGATCTCAATCTGAGTGCGACGATCACAAGGCAAGATGATGTTTGGTTGCCGAAACCGAGA
AACTATAGTTTTGGAATCAATTTGAGTTATCCATTGTTTAATGGTGGCAGAGATTATTACAATGTAAAGATTGCAAAAAC
AGAGTATGAAAAATCGATCCATACTCGAGATTCAAAAAAAAATATGCTCTCTTTTTCTTTGGAACAATCCTATCTTAATT
TTAAAAATGTTTCCGAACAACTTTTGGTATTAACTGAATTTTATAAGGCATCTGAGATCAGAGCAACAATTGCTCGGTCA
CAATATTCGAATGGTCTGATTAGTTTTGAAAATTGGGATCTTATCGAAAACGATTTGATCAATCGGGAGAAAAATTTGCT
AATTGGGAAAAGGGATCTTGGTTTAGCGGAAGCAACATACCTTCGCAATTTAGGAAAGTGTTTTGATGAAGACTAA

Upstream 100 bases:

>100_bases
GGAGTTGGTAGGTAAGGACTTGGATTCAGGAAATCGTTTGCATCGGATATTTTTTAAAAAATTTGGGAACTTTTTTGGAT
CCAAACGGGTTTAGTATATA

Downstream 100 bases:

>100_bases
AGTTTATATTTTTACTTTTGTATTTTTTCTTTCAGCAGTTTTGTATTACCTCATAGGTTTCAAGAAATCAAAAGAAGAAT
ATAAAATTGAATCAACTACA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 451; Mature: 451

Protein sequence:

>451_residues
MKYTLISSISCLVLSLTLFAETKKPIQLKDLWQKAVQSNPEYLSVKADYDKAFYENEKSYAGYLPTVNVLASARQSSANF
SGSGTVNDPLISGASNGNQTQNQQTNAGDSSPTAVNRYSVGLSTNQNLFSGFRDKSGIEKTEALLQAAKQTLNDSRLKIC
FELKSAYTQALYAKELHQLSLKIKERRIKNRDLVKLRYEVGREHKGSFLLSESFVKQSEYEVSFAERLFQTNWKEIERVI
ASPIEVTLDSTLLYEPILEKKFSEKEKSNLLDLHPSIMAEQSKVRAAQANIGVAEAGFYPDLNLSATITRQDDVWLPKPR
NYSFGINLSYPLFNGGRDYYNVKIAKTEYEKSIHTRDSKKNMLSFSLEQSYLNFKNVSEQLLVLTEFYKASEIRATIARS
QYSNGLISFENWDLIENDLINREKNLLIGKRDLGLAEATYLRNLGKCFDED

Sequences:

>Translated_451_residues
MKYTLISSISCLVLSLTLFAETKKPIQLKDLWQKAVQSNPEYLSVKADYDKAFYENEKSYAGYLPTVNVLASARQSSANF
SGSGTVNDPLISGASNGNQTQNQQTNAGDSSPTAVNRYSVGLSTNQNLFSGFRDKSGIEKTEALLQAAKQTLNDSRLKIC
FELKSAYTQALYAKELHQLSLKIKERRIKNRDLVKLRYEVGREHKGSFLLSESFVKQSEYEVSFAERLFQTNWKEIERVI
ASPIEVTLDSTLLYEPILEKKFSEKEKSNLLDLHPSIMAEQSKVRAAQANIGVAEAGFYPDLNLSATITRQDDVWLPKPR
NYSFGINLSYPLFNGGRDYYNVKIAKTEYEKSIHTRDSKKNMLSFSLEQSYLNFKNVSEQLLVLTEFYKASEIRATIARS
QYSNGLISFENWDLIENDLINREKNLLIGKRDLGLAEATYLRNLGKCFDED
>Mature_451_residues
MKYTLISSISCLVLSLTLFAETKKPIQLKDLWQKAVQSNPEYLSVKADYDKAFYENEKSYAGYLPTVNVLASARQSSANF
SGSGTVNDPLISGASNGNQTQNQQTNAGDSSPTAVNRYSVGLSTNQNLFSGFRDKSGIEKTEALLQAAKQTLNDSRLKIC
FELKSAYTQALYAKELHQLSLKIKERRIKNRDLVKLRYEVGREHKGSFLLSESFVKQSEYEVSFAERLFQTNWKEIERVI
ASPIEVTLDSTLLYEPILEKKFSEKEKSNLLDLHPSIMAEQSKVRAAQANIGVAEAGFYPDLNLSATITRQDDVWLPKPR
NYSFGINLSYPLFNGGRDYYNVKIAKTEYEKSIHTRDSKKNMLSFSLEQSYLNFKNVSEQLLVLTEFYKASEIRATIARS
QYSNGLISFENWDLIENDLINREKNLLIGKRDLGLAEATYLRNLGKCFDED

Specific function: In Pathogenic Strains It Allows The Bacteria To Invade Brain Microvascular Endothelial Cells (Bmec) Thus Allowing It To Cross The Blood-Brain Barrier And Cause Neonatal Meningitis. [C]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 51179; Mature: 51179

Theoretical pI: Translated: 8.59; Mature: 8.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYTLISSISCLVLSLTLFAETKKPIQLKDLWQKAVQSNPEYLSVKADYDKAFYENEKSY
CCEEHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEEECCCHHHHCCCCCC
AGYLPTVNVLASARQSSANFSGSGTVNDPLISGASNGNQTQNQQTNAGDSSPTAVNRYSV
CCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEE
GLSTNQNLFSGFRDKSGIEKTEALLQAAKQTLNDSRLKICFELKSAYTQALYAKELHQLS
CCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHH
LKIKERRIKNRDLVKLRYEVGREHKGSFLLSESFVKQSEYEVSFAERLFQTNWKEIERVI
HHHHHHHCCCCCCEEEEHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
ASPIEVTLDSTLLYEPILEKKFSEKEKSNLLDLHPSIMAEQSKVRAAQANIGVAEAGFYP
CCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEECCCCCC
DLNLSATITRQDDVWLPKPRNYSFGINLSYPLFNGGRDYYNVKIAKTEYEKSIHTRDSKK
CCCCEEEEEECCCCCCCCCCCCEEEEEEECCCCCCCCEEEEEEEEHHHHHHHHHCCCCHH
NMLSFSLEQSYLNFKNVSEQLLVLTEFYKASEIRATIARSQYSNGLISFENWDLIENDLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHH
NREKNLLIGKRDLGLAEATYLRNLGKCFDED
CCCCCEEEECCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKYTLISSISCLVLSLTLFAETKKPIQLKDLWQKAVQSNPEYLSVKADYDKAFYENEKSY
CCEEHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEEECCCHHHHCCCCCC
AGYLPTVNVLASARQSSANFSGSGTVNDPLISGASNGNQTQNQQTNAGDSSPTAVNRYSV
CCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEE
GLSTNQNLFSGFRDKSGIEKTEALLQAAKQTLNDSRLKICFELKSAYTQALYAKELHQLS
CCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHH
LKIKERRIKNRDLVKLRYEVGREHKGSFLLSESFVKQSEYEVSFAERLFQTNWKEIERVI
HHHHHHHCCCCCCEEEEHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
ASPIEVTLDSTLLYEPILEKKFSEKEKSNLLDLHPSIMAEQSKVRAAQANIGVAEAGFYP
CCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEECCCCCC
DLNLSATITRQDDVWLPKPRNYSFGINLSYPLFNGGRDYYNVKIAKTEYEKSIHTRDSKK
CCCCEEEEEECCCCCCCCCCCCEEEEEEECCCCCCCCEEEEEEEEHHHHHHHHHCCCCHH
NMLSFSLEQSYLNFKNVSEQLLVLTEFYKASEIRATIARSQYSNGLISFENWDLIENDLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHH
NREKNLLIGKRDLGLAEATYLRNLGKCFDED
CCCCCEEEECCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2303029; 2338917 [H]