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The map label for this gene is yqjQ [H]

Identifier: 183222109

GI number: 183222109

Start: 2843530

End: 2844333

Strand: Reverse

Name: yqjQ [H]

Synonym: LEPBI_I2751

Alternate gene names: 183222109

Gene position: 2844333-2843530 (Counterclockwise)

Preceding gene: 183222110

Following gene: 183222108

Centisome position: 79.02

GC content: 38.18

Gene sequence:

>804_bases
ATGAACGAGTTTTACCAAGATGAATGGGTATGGATCACAGGTGCCTCCTCTGGTATTGGCAAAGAATTAGTCAAACAAGC
CTATGCCCAAAAAGCAAAAATACTATTAGCATCTCGTAAAACCAAAGATTTAGAACGAATCGCAAAAGAAATTGGATTAG
AAAAAGGAAGATATGCAGTTGAAAAACTTGATTTGGAAAACTACCAACAGTGTTCTGAATTTGCGAAACGTTGTCTAAAA
AAATATGGAATTCCAAAAGTAGTCATCCATAACGGCGGTATTAGCCAACGCTCTCTTACCAAAGAAACCAATTTAGCCAC
CCTGGAAAAAATCATGAATACAAATTTTTTTGGAGCTGCTGAGTTAACGCGTGCAATGTTACCTGAAATATTAGGCAAAA
AATCGGTACATTTTGCTGTCATTTCCAGTGTTGCTGGAAAAATTGGAAGTCCTTTACGTTCTGCATACTCTGCTTCCAAA
TTTGCATTGGTAGGTTTTTTTCATGTCTTGCGAGCGGAAGAAGAAAAATCCGGAATCTTTGTGACCATGGTGTATCCTGG
ATTCATCCAAACCAACATTTCAATGAATGCACTCCAAGGAGATGGTTCCTCAACAGGTACGATGGATTCAGTCATCGAAT
CTGGATTGCCAGTGCAACTTTGTGCCCATAGAATCCTACATGCAGTTGCCAACAAACAGAGAGAGGTTGTCATCGCAGGG
ATCAAAGAAAAGTTTGGTTTGTTTCTACAAACGTTTATGCCTTCATTATTTTTTAAAATGATCCAAAAAGTAAAAGTGAG
ATAG

Upstream 100 bases:

>100_bases
TCCCAAGTGGATCCCTTTCTCATCATAAAAACAGGTTGTGAAAAATCCCTGATCCTAAATATTTTCTCTAGTTTCTTTTT
TTGAAATCTAAGGGGAATCT

Downstream 100 bases:

>100_bases
GGGGAATTAAATTTTGAGCCGCAAATTTGTTTATATTTTCATCGCGATCTTTTTCAGTGTGAGTCTATTATCCCAACAAA
CAATCCAGAATTATAAAATA

Product: putative dehydrogenase/reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MNEFYQDEWVWITGASSGIGKELVKQAYAQKAKILLASRKTKDLERIAKEIGLEKGRYAVEKLDLENYQQCSEFAKRCLK
KYGIPKVVIHNGGISQRSLTKETNLATLEKIMNTNFFGAAELTRAMLPEILGKKSVHFAVISSVAGKIGSPLRSAYSASK
FALVGFFHVLRAEEEKSGIFVTMVYPGFIQTNISMNALQGDGSSTGTMDSVIESGLPVQLCAHRILHAVANKQREVVIAG
IKEKFGLFLQTFMPSLFFKMIQKVKVR

Sequences:

>Translated_267_residues
MNEFYQDEWVWITGASSGIGKELVKQAYAQKAKILLASRKTKDLERIAKEIGLEKGRYAVEKLDLENYQQCSEFAKRCLK
KYGIPKVVIHNGGISQRSLTKETNLATLEKIMNTNFFGAAELTRAMLPEILGKKSVHFAVISSVAGKIGSPLRSAYSASK
FALVGFFHVLRAEEEKSGIFVTMVYPGFIQTNISMNALQGDGSSTGTMDSVIESGLPVQLCAHRILHAVANKQREVVIAG
IKEKFGLFLQTFMPSLFFKMIQKVKVR
>Mature_267_residues
MNEFYQDEWVWITGASSGIGKELVKQAYAQKAKILLASRKTKDLERIAKEIGLEKGRYAVEKLDLENYQQCSEFAKRCLK
KYGIPKVVIHNGGISQRSLTKETNLATLEKIMNTNFFGAAELTRAMLPEILGKKSVHFAVISSVAGKIGSPLRSAYSASK
FALVGFFHVLRAEEEKSGIFVTMVYPGFIQTNISMNALQGDGSSTGTMDSVIESGLPVQLCAHRILHAVANKQREVVIAG
IKEKFGLFLQTFMPSLFFKMIQKVKVR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI20149619, Length=265, Percent_Identity=36.2264150943396, Blast_Score=179, Evalue=2e-45,
Organism=Homo sapiens, GI7706318, Length=261, Percent_Identity=32.9501915708812, Blast_Score=142, Evalue=3e-34,
Organism=Homo sapiens, GI157739938, Length=266, Percent_Identity=28.5714285714286, Blast_Score=122, Evalue=3e-28,
Organism=Homo sapiens, GI7657478, Length=184, Percent_Identity=33.695652173913, Blast_Score=88, Evalue=6e-18,
Organism=Homo sapiens, GI32455239, Length=240, Percent_Identity=30.8333333333333, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI5031765, Length=240, Percent_Identity=30.8333333333333, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI4503817, Length=275, Percent_Identity=25.4545454545455, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI142976729, Length=267, Percent_Identity=25.8426966292135, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI210032110, Length=195, Percent_Identity=27.6923076923077, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI150247226, Length=197, Percent_Identity=28.4263959390863, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI40807363, Length=255, Percent_Identity=27.0588235294118, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI7705855, Length=199, Percent_Identity=27.6381909547739, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI19743808, Length=189, Percent_Identity=23.2804232804233, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1786701, Length=197, Percent_Identity=34.010152284264, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI87082100, Length=184, Percent_Identity=26.6304347826087, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1787335, Length=198, Percent_Identity=25.7575757575758, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787526, Length=200, Percent_Identity=29, Blast_Score=71, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17570069, Length=258, Percent_Identity=33.3333333333333, Blast_Score=127, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI71997402, Length=254, Percent_Identity=31.8897637795276, Blast_Score=123, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17508895, Length=231, Percent_Identity=24.6753246753247, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17567345, Length=264, Percent_Identity=26.5151515151515, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI71994604, Length=185, Percent_Identity=28.6486486486486, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17507613, Length=191, Percent_Identity=27.2251308900524, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI32563809, Length=191, Percent_Identity=27.2251308900524, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17564282, Length=220, Percent_Identity=25, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71994600, Length=187, Percent_Identity=29.4117647058824, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17551412, Length=212, Percent_Identity=27.3584905660377, Blast_Score=64, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=237, Percent_Identity=28.2700421940928, Blast_Score=83, Evalue=5e-17,
Organism=Drosophila melanogaster, GI21358495, Length=262, Percent_Identity=38.1679389312977, Blast_Score=181, Evalue=4e-46,
Organism=Drosophila melanogaster, GI24580925, Length=231, Percent_Identity=26.4069264069264, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI23397609, Length=193, Percent_Identity=31.6062176165803, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24640442, Length=195, Percent_Identity=30.7692307692308, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI28571526, Length=190, Percent_Identity=28.4210526315789, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24647946, Length=202, Percent_Identity=32.6732673267327, Blast_Score=71, Evalue=9e-13,
Organism=Drosophila melanogaster, GI45553409, Length=202, Percent_Identity=32.6732673267327, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24647948, Length=202, Percent_Identity=32.6732673267327, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24644339, Length=185, Percent_Identity=29.1891891891892, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21357041, Length=190, Percent_Identity=27.8947368421053, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24584752, Length=196, Percent_Identity=27.5510204081633, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI221510726, Length=196, Percent_Identity=28.0612244897959, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 29662; Mature: 29662

Theoretical pI: Translated: 10.19; Mature: 10.19

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEFYQDEWVWITGASSGIGKELVKQAYAQKAKILLASRKTKDLERIAKEIGLEKGRYAV
CCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHH
EKLDLENYQQCSEFAKRCLKKYGIPKVVIHNGGISQRSLTKETNLATLEKIMNTNFFGAA
HHHCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCHH
ELTRAMLPEILGKKSVHFAVISSVAGKIGSPLRSAYSASKFALVGFFHVLRAEEEKSGIF
HHHHHHHHHHHCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEE
VTMVYPGFIQTNISMNALQGDGSSTGTMDSVIESGLPVQLCAHRILHAVANKQREVVIAG
EEEECCCEEEECCEEEEECCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEEC
IKEKFGLFLQTFMPSLFFKMIQKVKVR
HHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNEFYQDEWVWITGASSGIGKELVKQAYAQKAKILLASRKTKDLERIAKEIGLEKGRYAV
CCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHH
EKLDLENYQQCSEFAKRCLKKYGIPKVVIHNGGISQRSLTKETNLATLEKIMNTNFFGAA
HHHCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCHH
ELTRAMLPEILGKKSVHFAVISSVAGKIGSPLRSAYSASKFALVGFFHVLRAEEEKSGIF
HHHHHHHHHHHCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEE
VTMVYPGFIQTNISMNALQGDGSSTGTMDSVIESGLPVQLCAHRILHAVANKQREVVIAG
EEEECCCEEEECCEEEEECCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEEC
IKEKFGLFLQTFMPSLFFKMIQKVKVR
HHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]