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The map label for this gene is 183221905

Identifier: 183221905

GI number: 183221905

Start: 2632227

End: 2633924

Strand: Reverse

Name: 183221905

Synonym: LEPBI_I2544

Alternate gene names: NA

Gene position: 2633924-2632227 (Counterclockwise)

Preceding gene: 183221906

Following gene: 183221904

Centisome position: 73.17

GC content: 42.52

Gene sequence:

>1698_bases
ATGACCAAGCCACTCACCGTACAAAGTGATAAAACAATGCTTCTTGAGGTGGATAACCCAGAATTTGAAGCGTGTCGGGA
CCTCGTTGCCAAGTTTGCCGAGCTTGAAAAAAGCCCGGAATATATGCATACCTACCGTATTTCTCCACTTTCTTTGTGGA
ATGCTGCATCGATCAAAATGACGGCAGAAGAGATCATTGAAGGCCTGACTAAATTTGCCCGTTATTCTGTTCCTAAAAAC
GTGATGAACGAAATCCGAGAACAAATCTCTCGGTATGGAAAAGTAAAGCTCGTCAAAGAAGAATCCGGCGAATTGTACAT
CATCTCCAATGAAAAAGGTTTCATCACAGAAATTGCGAACAACCGTGCCGTCCAACCCTTTGTGGATGGAATGGAAGGTG
ATAAAATCCGAATCAAAAAAGAATATCGTGGTCACATCAAACAAGCGTTAATCAAGATTGGTTTTCCTGTGGAAGACCTT
GCTGGTTACGATGAAGGAAACAAATACCCATTTAACTTACGTCCTACGACAAAAGGTGGGATTAAGTTTGGGATGCGTGA
TTACCAAAGAGCATCTGTGGAAGCCTTTCACGCAGGTGGACGTAACGAAGGGGGATCTGGTGTTGTGGTACTTCCTTGTG
GTGCGGGGAAAACCATCGTGGGTATGGGAGTGATGCAAATTGTTGGGGCAGAAACACTCATTCTTGTGACGAACACTTTA
TCTATCCGTCAGTGGCGAAATGAAATCCTAGACAAAACGGACATTCCAGAATCAGACATCGGTGAATATTCAGGTGAGAT
GAAAGAAATCAAACCGATCACCATTGCAACTTATAATATCTTAACTCATAGAAAGAAAAAAGGTGGGGACTTTACCCATT
TTCATATCTTCAGTGCCAATAACTGGGGACTTATCGTTTATGATGAGGTTCACTTATTACCAGCACCAGTCTTTCGTATG
ACTTCTGAACTACAAGCCAAACGTAGGTTAGGTCTCACGGCAACACTTGTGCGTGAAGATGGATTGGAAGAAGATGTATT
TTCTCTCATCGGTCCGAAAAAATACGATGTACCATGGAAAGAACTGGAAGCCAAATCTTGGATTGCCGAAGCCAATTGTG
TAGAAATCCGTGTTCCTATGGAAGATGACCTTCGTATGAAGTATTCTGTTGCTGATGACCGCGAAAAGTTTCGTTTGGCT
TCCGAAAATCCAGAGAAACTCCGTGCGATCAGCTATATTTTGAAAAAACACTCCACTAACAATATTTTGGTGATTGGGCA
GTACATCAATCAGCTAGAAGAAATTTCCAATACCTTCAAAATCCCTTTGATTACTGGAAAAACCCCACTCCCTGAAAGAC
AAGAACTCTACCAAGCGTTCCGAACAGGCCAGATCAAACAACTTGTGGTTTCAAAGGTAGCAAACTTTTCCATCGACTTA
CCAGATGCCAACATTGCCATCCAGGTATCGGGAACATTTGGTTCCAGACAAGAGGAAGCACAACGATTGGGGCGTATCCT
ACGTCCAAAAGCACAGGACAATACTGCGATTTTTTACTCACTGATTTCGCGTGATACAAATGAAGAGAGATTCGGACAAA
ACCGACAACTCTTCCTCACCGAACAAGGGTATGAATACGAAATTTATACTTTGGACCAGTTCAAAGAAACGGTTCCAGAA
GAATCACTCACGAAATAG

Upstream 100 bases:

>100_bases
CCCTAAAAATGGCAGGAAAATGCATCCAAAATCTCTTAAAATCAAATGGGTTGACAGGGCGGTTTCTCTACACAGCCTGG
TTAAATTGAGAGGGAATACC

Downstream 100 bases:

>100_bases
AGGACAAAATGAAACTTGTAGCAAAACGACTCGATGTCGTAGAACCTTCTCCCACTCTCGCGATCACGGCGAAAGCCAAT
CAGTTAAAAGCGAGTGGCCT

Product: putative DNA repair helicase

Products: NA

Alternate protein names: DNA Repair Helicase; Type III Restriction Res Subunit; Helicase Domain-Containing Protein; Helicase Domain Protein; ATP-Dependent DNA Helicase; DNA Repair Helicase RAD; DNA Repair Helicase Rad; Type III Restriction Res Subunit Family; Superfamily II DNA/RNA Helicase; Helicase; DNA/RNA Helicase; DNA Repair Protein Rad; DNA Repair Protein; DNA Repair Protein RAD; DNA Helicase; DNA/RNA Helicase Superfamily II; Helicase-Like Protein; Helicase Protein; ATP-Dependent Helicase; DNA Or RNA Helicase Of Superfamily II; DNA/RNA Repair Helicase; Helicase DNA Repair; Helicase DNA Repair Rad; XPB/RAD25-Related Helicase; ATP-Dependet DEAD/DEAH Box Helicase; DEAD/DEAH Box Helicase-Like; DNA-Helicase; DNA Or RNA Helicase Of Superfamily Protein II; DEAD/DEAH Box Helicase; Helicase ATP-Dependent; DNA Or RNA Helicase; RAD25-Type DNA Repair Helicase; DNA Repair Related Protein; Restriction Endonuclease Family Protein; Helicase ATP-Dependent Intein-Containing; DEAD/DEAH Box Helicase Domain-Containing Protein

Number of amino acids: Translated: 565; Mature: 564

Protein sequence:

>565_residues
MTKPLTVQSDKTMLLEVDNPEFEACRDLVAKFAELEKSPEYMHTYRISPLSLWNAASIKMTAEEIIEGLTKFARYSVPKN
VMNEIREQISRYGKVKLVKEESGELYIISNEKGFITEIANNRAVQPFVDGMEGDKIRIKKEYRGHIKQALIKIGFPVEDL
AGYDEGNKYPFNLRPTTKGGIKFGMRDYQRASVEAFHAGGRNEGGSGVVVLPCGAGKTIVGMGVMQIVGAETLILVTNTL
SIRQWRNEILDKTDIPESDIGEYSGEMKEIKPITIATYNILTHRKKKGGDFTHFHIFSANNWGLIVYDEVHLLPAPVFRM
TSELQAKRRLGLTATLVREDGLEEDVFSLIGPKKYDVPWKELEAKSWIAEANCVEIRVPMEDDLRMKYSVADDREKFRLA
SENPEKLRAISYILKKHSTNNILVIGQYINQLEEISNTFKIPLITGKTPLPERQELYQAFRTGQIKQLVVSKVANFSIDL
PDANIAIQVSGTFGSRQEEAQRLGRILRPKAQDNTAIFYSLISRDTNEERFGQNRQLFLTEQGYEYEIYTLDQFKETVPE
ESLTK

Sequences:

>Translated_565_residues
MTKPLTVQSDKTMLLEVDNPEFEACRDLVAKFAELEKSPEYMHTYRISPLSLWNAASIKMTAEEIIEGLTKFARYSVPKN
VMNEIREQISRYGKVKLVKEESGELYIISNEKGFITEIANNRAVQPFVDGMEGDKIRIKKEYRGHIKQALIKIGFPVEDL
AGYDEGNKYPFNLRPTTKGGIKFGMRDYQRASVEAFHAGGRNEGGSGVVVLPCGAGKTIVGMGVMQIVGAETLILVTNTL
SIRQWRNEILDKTDIPESDIGEYSGEMKEIKPITIATYNILTHRKKKGGDFTHFHIFSANNWGLIVYDEVHLLPAPVFRM
TSELQAKRRLGLTATLVREDGLEEDVFSLIGPKKYDVPWKELEAKSWIAEANCVEIRVPMEDDLRMKYSVADDREKFRLA
SENPEKLRAISYILKKHSTNNILVIGQYINQLEEISNTFKIPLITGKTPLPERQELYQAFRTGQIKQLVVSKVANFSIDL
PDANIAIQVSGTFGSRQEEAQRLGRILRPKAQDNTAIFYSLISRDTNEERFGQNRQLFLTEQGYEYEIYTLDQFKETVPE
ESLTK
>Mature_564_residues
TKPLTVQSDKTMLLEVDNPEFEACRDLVAKFAELEKSPEYMHTYRISPLSLWNAASIKMTAEEIIEGLTKFARYSVPKNV
MNEIREQISRYGKVKLVKEESGELYIISNEKGFITEIANNRAVQPFVDGMEGDKIRIKKEYRGHIKQALIKIGFPVEDLA
GYDEGNKYPFNLRPTTKGGIKFGMRDYQRASVEAFHAGGRNEGGSGVVVLPCGAGKTIVGMGVMQIVGAETLILVTNTLS
IRQWRNEILDKTDIPESDIGEYSGEMKEIKPITIATYNILTHRKKKGGDFTHFHIFSANNWGLIVYDEVHLLPAPVFRMT
SELQAKRRLGLTATLVREDGLEEDVFSLIGPKKYDVPWKELEAKSWIAEANCVEIRVPMEDDLRMKYSVADDREKFRLAS
ENPEKLRAISYILKKHSTNNILVIGQYINQLEEISNTFKIPLITGKTPLPERQELYQAFRTGQIKQLVVSKVANFSIDLP
DANIAIQVSGTFGSRQEEAQRLGRILRPKAQDNTAIFYSLISRDTNEERFGQNRQLFLTEQGYEYEIYTLDQFKETVPEE
SLTK

Specific function: Unknown

COG id: COG1061

COG function: function code KL; DNA or RNA helicases of superfamily II

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI4557563, Length=630, Percent_Identity=31.7460317460317, Blast_Score=293, Evalue=3e-79,
Organism=Caenorhabditis elegans, GI17556358, Length=639, Percent_Identity=30.2034428794992, Blast_Score=254, Evalue=1e-67,
Organism=Saccharomyces cerevisiae, GI6322048, Length=429, Percent_Identity=34.7319347319347, Blast_Score=262, Evalue=1e-70,
Organism=Drosophila melanogaster, GI221331068, Length=423, Percent_Identity=35.9338061465721, Blast_Score=248, Evalue=7e-66,
Organism=Drosophila melanogaster, GI24662247, Length=423, Percent_Identity=35.9338061465721, Blast_Score=248, Evalue=7e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 64246; Mature: 64115

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKPLTVQSDKTMLLEVDNPEFEACRDLVAKFAELEKSPEYMHTYRISPLSLWNAASIKM
CCCCCEEECCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCHHEEEECCCCEECCCCEEEE
TAEEIIEGLTKFARYSVPKNVMNEIREQISRYGKVKLVKEESGELYIISNEKGFITEIAN
CHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEEECCCCEEEEECCCCCEEECCC
NRAVQPFVDGMEGDKIRIKKEYRGHIKQALIKIGFPVEDLAGYDEGNKYPFNLRPTTKGG
CCCCCHHHCCCCCCEEEEEHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCEEECCCCCCC
IKFGMRDYQRASVEAFHAGGRNEGGSGVVVLPCGAGKTIVGMGVMQIVGAETLILVTNTL
EEECCHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCH
SIRQWRNEILDKTDIPESDIGEYSGEMKEIKPITIATYNILTHRKKKGGDFTHFHIFSAN
HHHHHHHHHCCCCCCCCCHHHHHCCCHHHCCCEEEEEEHHHHHHHCCCCCEEEEEEEECC
NWGLIVYDEVHLLPAPVFRMTSELQAKRRLGLTATLVREDGLEEDVFSLIGPKKYDVPWK
CCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCEEEEEHHCCCHHHHHHHHCCCCCCCCHH
ELEAKSWIAEANCVEIRVPMEDDLRMKYSVADDREKFRLASENPEKLRAISYILKKHSTN
HHHHHHHCCCCCEEEEECCCCCCCEEEEEECCCHHHHEECCCCHHHHHHHHHHHHHCCCC
NILVIGQYINQLEEISNTFKIPLITGKTPLPERQELYQAFRTGQIKQLVVSKVANFSIDL
CEEEEHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCEEEC
PDANIAIQVSGTFGSRQEEAQRLGRILRPKAQDNTAIFYSLISRDTNEERFGQNRQLFLT
CCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCEEEEEEHHCCCCHHHCCCCCEEEEE
EQGYEYEIYTLDQFKETVPEESLTK
CCCCEEEEEEHHHHHHHCCHHHCCC
>Mature Secondary Structure 
TKPLTVQSDKTMLLEVDNPEFEACRDLVAKFAELEKSPEYMHTYRISPLSLWNAASIKM
CCCCEEECCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCHHEEEECCCCEECCCCEEEE
TAEEIIEGLTKFARYSVPKNVMNEIREQISRYGKVKLVKEESGELYIISNEKGFITEIAN
CHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEEECCCCEEEEECCCCCEEECCC
NRAVQPFVDGMEGDKIRIKKEYRGHIKQALIKIGFPVEDLAGYDEGNKYPFNLRPTTKGG
CCCCCHHHCCCCCCEEEEEHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCEEECCCCCCC
IKFGMRDYQRASVEAFHAGGRNEGGSGVVVLPCGAGKTIVGMGVMQIVGAETLILVTNTL
EEECCHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCH
SIRQWRNEILDKTDIPESDIGEYSGEMKEIKPITIATYNILTHRKKKGGDFTHFHIFSAN
HHHHHHHHHCCCCCCCCCHHHHHCCCHHHCCCEEEEEEHHHHHHHCCCCCEEEEEEEECC
NWGLIVYDEVHLLPAPVFRMTSELQAKRRLGLTATLVREDGLEEDVFSLIGPKKYDVPWK
CCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCEEEEEHHCCCHHHHHHHHCCCCCCCCHH
ELEAKSWIAEANCVEIRVPMEDDLRMKYSVADDREKFRLASENPEKLRAISYILKKHSTN
HHHHHHHCCCCCEEEEECCCCCCCEEEEEECCCHHHHEECCCCHHHHHHHHHHHHHCCCC
NILVIGQYINQLEEISNTFKIPLITGKTPLPERQELYQAFRTGQIKQLVVSKVANFSIDL
CEEEEHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCEEEC
PDANIAIQVSGTFGSRQEEAQRLGRILRPKAQDNTAIFYSLISRDTNEERFGQNRQLFLT
CCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCEEEEEEHHCCCCHHHCCCCCEEEEE
EQGYEYEIYTLDQFKETVPEESLTK
CCCCEEEEEEHHHHHHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA