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The map label for this gene is mmgC [H]

Identifier: 183221848

GI number: 183221848

Start: 2561137

End: 2562891

Strand: Reverse

Name: mmgC [H]

Synonym: LEPBI_I2480

Alternate gene names: 183221848

Gene position: 2562891-2561137 (Counterclockwise)

Preceding gene: 183221849

Following gene: 183221847

Centisome position: 71.2

GC content: 40.28

Gene sequence:

>1755_bases
ATGATCGCTAATAATTATTTTTCAGATGATAAGGACTTACAGTTAATCTACAACCAATTGATCGATTGGAAATCAATCGT
TAAAGAAGCGGAAGGGGAAGGCTTTATAGACCATCAAATTTATTCAGAGACTCAAAACAATCGTTATGAAATGGCACCCT
CAAACTTTGATGAAGCAATGGAACTATATACTTCTAGTTTGGACGCGATGGGAGATTTTTTTGGAAAAGATGTTTCTCAA
AAGTCCCAAATCATGGATCGAAATGAACTGAAATATGAAAATGGAAAGGTCATTTTTCCTAAGGAAACTGTCGAAATATA
CGAAAAATTCCGAAACACTGGATTACTTGGTTATTCTCTCCCAAGAGAAGCGGGTGGATTGAATTTTCCGGCAACCGTTG
GCGCGTTTTATGCCATGATTATGGCTCGCGCCGATGTTGCATTTTGTATGACAACCACTCTCCTCAATTTGGCACAAATC
GTATCAAGATTTGGAACTAAGGAACAAATTGAAACTTATGCAACGAAAGCAGCAACAGGTGATTGTTTGTTTGCGATGTC
ACTCACGGAACCAGATTTTGGATCTGATTTGAATAGTGTTCGGACAGTGGCGATCAAACAAGAAGACGGATCATATCGAC
TCACAGGTACGAAACGATTCATATCCCAAGGTTGTGGTTTAGGTGATTATCCCGCACTTTTGTTAACGTTAGCAAGGACA
GGAAAACCAGATGGTGGTGCCAGAGGACTATCCGTATTTTTAGTGAAAAGTTCTGACATCACTGTCGCAGGCATTGAGAA
AAAAATGGGGCTCCATGGTTCTCCAACTTGCGAGATCGTTTATGAGAATAGTTATGGAGAAATATTAGGCGAAGAAGGAC
TTGGACTCACTCGTTACACAGCAGGGATGACAAACTTTATGAGGCTTGTGAGTGCCTCGGGAGGATGTGGTGGCGGTGCT
GCCGCTTATTTTGAATCCCTCAAATATGCAAATGAACGGAATCAGTTTGGAAAACCAATTTTTGAAATCCCTGCCGTTTT
CGAAATGGTTCATAAGATCAAAAGGGAAACAAATGCAATGCGACTCTTAACCTTAGAAACCGCTCGAGTGATTGATATGT
ACCAACACCATCAAATTCGACTCGAAAAACAAGGGTTACCTGATCGAGACATACGTAAGGATGAAAAAGTAAAATATTGG
TCAACCCTAGCATCCATTCTCACACCTATCGCGAAATATTACAGTTCAGAAGAGGGTCATAAATGTACAAGTATCGCCGT
ACAGGTATTTGGTGGTGCAGGATATACTGAAGATTATGATATCTCCCGAATGTTCCGTGATTCTAGAATCAATACAATTT
ATGAAGGTACTTCCCAAATCCATGTACGAATTTCCACGGGTGCCATCCTTGCGGGTATGGCAGGAGATGGAAATTTTAGA
AAGTATCTAAATTCACTCAAAACAGAGATTCCAAATCCTTCTTTGTATTTATTGGAACAGGAGAAGCTACTGGAATCATC
CATCCAATGCATGCGATTGATCGATTCAGAAGCGAGAAAAGAAACAGTCGCAGAAAATTTAATGATCCAAATGGCTCGTT
ACCTTTGTTCTCTATTGTATGAACAAGCTGTCTCTAAAATTACGGACACAGAAATGAAACCAATATGGGAATTCGATTGC
CAGTCCTATGTTGTGGACAGTGCGGCAACGGCCCAATCTAGCCTTTATCGCATCCAACATTTTGGAAAAGGATAA

Upstream 100 bases:

>100_bases
ACCATATTGATCGGTGGTGCAAAGGATGCAAAAAACATCGACGCCAAACGAGCATTTTTCGAAGGACTAGAAGCAGCATA
CAGTATTTAAGGAGATAAAT

Downstream 100 bases:

>100_bases
AGATTTCATCTCTGATCATAAGAGGGATTGACGGATTCAAATTTTTCACTGATTCTTGATTCCCTGAGGTATTGTATGAA
AACAATTTTGAAGTTGGTTT

Product: acyl-CoA dehydrogenase

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 584; Mature: 584

Protein sequence:

>584_residues
MIANNYFSDDKDLQLIYNQLIDWKSIVKEAEGEGFIDHQIYSETQNNRYEMAPSNFDEAMELYTSSLDAMGDFFGKDVSQ
KSQIMDRNELKYENGKVIFPKETVEIYEKFRNTGLLGYSLPREAGGLNFPATVGAFYAMIMARADVAFCMTTTLLNLAQI
VSRFGTKEQIETYATKAATGDCLFAMSLTEPDFGSDLNSVRTVAIKQEDGSYRLTGTKRFISQGCGLGDYPALLLTLART
GKPDGGARGLSVFLVKSSDITVAGIEKKMGLHGSPTCEIVYENSYGEILGEEGLGLTRYTAGMTNFMRLVSASGGCGGGA
AAYFESLKYANERNQFGKPIFEIPAVFEMVHKIKRETNAMRLLTLETARVIDMYQHHQIRLEKQGLPDRDIRKDEKVKYW
STLASILTPIAKYYSSEEGHKCTSIAVQVFGGAGYTEDYDISRMFRDSRINTIYEGTSQIHVRISTGAILAGMAGDGNFR
KYLNSLKTEIPNPSLYLLEQEKLLESSIQCMRLIDSEARKETVAENLMIQMARYLCSLLYEQAVSKITDTEMKPIWEFDC
QSYVVDSAATAQSSLYRIQHFGKG

Sequences:

>Translated_584_residues
MIANNYFSDDKDLQLIYNQLIDWKSIVKEAEGEGFIDHQIYSETQNNRYEMAPSNFDEAMELYTSSLDAMGDFFGKDVSQ
KSQIMDRNELKYENGKVIFPKETVEIYEKFRNTGLLGYSLPREAGGLNFPATVGAFYAMIMARADVAFCMTTTLLNLAQI
VSRFGTKEQIETYATKAATGDCLFAMSLTEPDFGSDLNSVRTVAIKQEDGSYRLTGTKRFISQGCGLGDYPALLLTLART
GKPDGGARGLSVFLVKSSDITVAGIEKKMGLHGSPTCEIVYENSYGEILGEEGLGLTRYTAGMTNFMRLVSASGGCGGGA
AAYFESLKYANERNQFGKPIFEIPAVFEMVHKIKRETNAMRLLTLETARVIDMYQHHQIRLEKQGLPDRDIRKDEKVKYW
STLASILTPIAKYYSSEEGHKCTSIAVQVFGGAGYTEDYDISRMFRDSRINTIYEGTSQIHVRISTGAILAGMAGDGNFR
KYLNSLKTEIPNPSLYLLEQEKLLESSIQCMRLIDSEARKETVAENLMIQMARYLCSLLYEQAVSKITDTEMKPIWEFDC
QSYVVDSAATAQSSLYRIQHFGKG
>Mature_584_residues
MIANNYFSDDKDLQLIYNQLIDWKSIVKEAEGEGFIDHQIYSETQNNRYEMAPSNFDEAMELYTSSLDAMGDFFGKDVSQ
KSQIMDRNELKYENGKVIFPKETVEIYEKFRNTGLLGYSLPREAGGLNFPATVGAFYAMIMARADVAFCMTTTLLNLAQI
VSRFGTKEQIETYATKAATGDCLFAMSLTEPDFGSDLNSVRTVAIKQEDGSYRLTGTKRFISQGCGLGDYPALLLTLART
GKPDGGARGLSVFLVKSSDITVAGIEKKMGLHGSPTCEIVYENSYGEILGEEGLGLTRYTAGMTNFMRLVSASGGCGGGA
AAYFESLKYANERNQFGKPIFEIPAVFEMVHKIKRETNAMRLLTLETARVIDMYQHHQIRLEKQGLPDRDIRKDEKVKYW
STLASILTPIAKYYSSEEGHKCTSIAVQVFGGAGYTEDYDISRMFRDSRINTIYEGTSQIHVRISTGAILAGMAGDGNFR
KYLNSLKTEIPNPSLYLLEQEKLLESSIQCMRLIDSEARKETVAENLMIQMARYLCSLLYEQAVSKITDTEMKPIWEFDC
QSYVVDSAATAQSSLYRIQHFGKG

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI21361497, Length=414, Percent_Identity=30.9178743961353, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI4501859, Length=458, Percent_Identity=28.82096069869, Blast_Score=133, Evalue=5e-31,
Organism=Homo sapiens, GI4557233, Length=381, Percent_Identity=28.0839895013123, Blast_Score=114, Evalue=3e-25,
Organism=Homo sapiens, GI7656849, Length=399, Percent_Identity=27.3182957393484, Blast_Score=106, Evalue=5e-23,
Organism=Homo sapiens, GI4557235, Length=399, Percent_Identity=28.3208020050125, Blast_Score=106, Evalue=5e-23,
Organism=Homo sapiens, GI76496475, Length=399, Percent_Identity=28.3208020050125, Blast_Score=106, Evalue=6e-23,
Organism=Homo sapiens, GI4501857, Length=371, Percent_Identity=27.7628032345013, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI226958412, Length=400, Percent_Identity=25.75, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI226958414, Length=364, Percent_Identity=25.8241758241758, Blast_Score=94, Evalue=5e-19,
Organism=Homo sapiens, GI187960098, Length=374, Percent_Identity=26.2032085561497, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI4557231, Length=374, Percent_Identity=26.2032085561497, Blast_Score=92, Evalue=1e-18,
Organism=Escherichia coli, GI87081958, Length=380, Percent_Identity=28.6842105263158, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI87082384, Length=285, Percent_Identity=28.7719298245614, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI1786223, Length=380, Percent_Identity=23.9473684210526, Blast_Score=98, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17508101, Length=365, Percent_Identity=26.3013698630137, Blast_Score=114, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17538396, Length=365, Percent_Identity=28.4931506849315, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17534899, Length=306, Percent_Identity=30.0653594771242, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17506239, Length=364, Percent_Identity=25.8241758241758, Blast_Score=105, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI86563381, Length=409, Percent_Identity=25.4278728606357, Blast_Score=102, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI86563383, Length=409, Percent_Identity=25.4278728606357, Blast_Score=102, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI17569725, Length=420, Percent_Identity=27.3809523809524, Blast_Score=99, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI71985184, Length=373, Percent_Identity=27.3458445040214, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17533517, Length=313, Percent_Identity=28.4345047923323, Blast_Score=85, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17505929, Length=418, Percent_Identity=24.8803827751196, Blast_Score=82, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17570075, Length=303, Percent_Identity=26.4026402640264, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71990804, Length=274, Percent_Identity=26.6423357664234, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71985192, Length=288, Percent_Identity=29.1666666666667, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI32563615, Length=253, Percent_Identity=25.6916996047431, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24666513, Length=363, Percent_Identity=29.7520661157025, Blast_Score=126, Evalue=5e-29,
Organism=Drosophila melanogaster, GI21356377, Length=407, Percent_Identity=27.027027027027, Blast_Score=124, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24646207, Length=410, Percent_Identity=26.5853658536585, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24660351, Length=365, Percent_Identity=28.7671232876712, Blast_Score=102, Evalue=1e-21,
Organism=Drosophila melanogaster, GI281363737, Length=397, Percent_Identity=27.7078085642317, Blast_Score=101, Evalue=2e-21,
Organism=Drosophila melanogaster, GI21355753, Length=405, Percent_Identity=26.9135802469136, Blast_Score=97, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 65296; Mature: 65296

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIANNYFSDDKDLQLIYNQLIDWKSIVKEAEGEGFIDHQIYSETQNNRYEMAPSNFDEAM
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCEEECCCCHHHHH
ELYTSSLDAMGDFFGKDVSQKSQIMDRNELKYENGKVIFPKETVEIYEKFRNTGLLGYSL
HHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEECCCCEECCHHHHHHHHHHHHCCCEEECC
PREAGGLNFPATVGAFYAMIMARADVAFCMTTTLLNLAQIVSRFGTKEQIETYATKAATG
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCC
DCLFAMSLTEPDFGSDLNSVRTVAIKQEDGSYRLTGTKRFISQGCGLGDYPALLLTLART
CEEEEEECCCCCCCCCCCCEEEEEEEECCCCEEECHHHHHHHCCCCCCCHHHHHHHHHHC
GKPDGGARGLSVFLVKSSDITVAGIEKKMGLHGSPTCEIVYENSYGEILGEEGLGLTRYT
CCCCCCCCCEEEEEEECCCEEEEEHHHHCCCCCCCCEEEEEECCCHHHHCCCCCCHHHHH
AGMTNFMRLVSASGGCGGGAAAYFESLKYANERNQFGKPIFEIPAVFEMVHKIKRETNAM
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCE
RLLTLETARVIDMYQHHQIRLEKQGLPDRDIRKDEKVKYWSTLASILTPIAKYYSSEEGH
EEEEEHHHHHHHHHHHHHEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
KCTSIAVQVFGGAGYTEDYDISRMFRDSRINTIYEGTSQIHVRISTGAILAGMAGDGNFR
HHHHHHEEEECCCCCCCCCHHHHHHHHHCCCCEECCCCEEEEEEECCEEEEECCCCCHHH
KYLNSLKTEIPNPSLYLLEQEKLLESSIQCMRLIDSEARKETVAENLMIQMARYLCSLLY
HHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQAVSKITDTEMKPIWEFDCQSYVVDSAATAQSSLYRIQHFGKG
HHHHHHHHCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIANNYFSDDKDLQLIYNQLIDWKSIVKEAEGEGFIDHQIYSETQNNRYEMAPSNFDEAM
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCEEECCCCHHHHH
ELYTSSLDAMGDFFGKDVSQKSQIMDRNELKYENGKVIFPKETVEIYEKFRNTGLLGYSL
HHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEECCCCEECCHHHHHHHHHHHHCCCEEECC
PREAGGLNFPATVGAFYAMIMARADVAFCMTTTLLNLAQIVSRFGTKEQIETYATKAATG
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCC
DCLFAMSLTEPDFGSDLNSVRTVAIKQEDGSYRLTGTKRFISQGCGLGDYPALLLTLART
CEEEEEECCCCCCCCCCCCEEEEEEEECCCCEEECHHHHHHHCCCCCCCHHHHHHHHHHC
GKPDGGARGLSVFLVKSSDITVAGIEKKMGLHGSPTCEIVYENSYGEILGEEGLGLTRYT
CCCCCCCCCEEEEEEECCCEEEEEHHHHCCCCCCCCEEEEEECCCHHHHCCCCCCHHHHH
AGMTNFMRLVSASGGCGGGAAAYFESLKYANERNQFGKPIFEIPAVFEMVHKIKRETNAM
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCE
RLLTLETARVIDMYQHHQIRLEKQGLPDRDIRKDEKVKYWSTLASILTPIAKYYSSEEGH
EEEEEHHHHHHHHHHHHHEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
KCTSIAVQVFGGAGYTEDYDISRMFRDSRINTIYEGTSQIHVRISTGAILAGMAGDGNFR
HHHHHHEEEECCCCCCCCCHHHHHHHHHCCCCEECCCCEEEEEEECCEEEEECCCCCHHH
KYLNSLKTEIPNPSLYLLEQEKLLESSIQCMRLIDSEARKETVAENLMIQMARYLCSLLY
HHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQAVSKITDTEMKPIWEFDCQSYVVDSAATAQSSLYRIQHFGKG
HHHHHHHHCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]