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The map label for this gene is divJ [H]

Identifier: 183221827

GI number: 183221827

Start: 2541215

End: 2542519

Strand: Reverse

Name: divJ [H]

Synonym: LEPBI_I2458

Alternate gene names: 183221827

Gene position: 2542519-2541215 (Counterclockwise)

Preceding gene: 183221828

Following gene: 183221826

Centisome position: 70.63

GC content: 33.1

Gene sequence:

>1305_bases
ATGAAATTTGTATTCAATTCTATTGGAATACGTTTTCTCTTAAACTTAGGAGTTAACAATCAATTAGATTTACAAACTTC
CGTTAGAGTCCAATTAGCAAACTTAATCGCCATTCTCGGTATTTTATCAAATATACAATATTCAATTCTTTTTACCATCG
CAGGTGCACCATATGTTTGGATTATGAATCTAATCCATTTCACCGTAGTATGTACGTTATCCTATATATTGTATTTGAAC
AAAAAAGAGAAATATGTTACTGCGCGGATCCTATTAGTTTTTACAATATCGGTTCCTTTGTTATTTGTTTCGTTTGTAAG
TTTTGGAAATACGGGAGGATTTTATTATTATTTTTTAGTGTTTGCATTGGCTCCTTTTGTTTTGTTTTCATACGAAGAAA
AATTTTGGATTTTGTTTGTATTTTTCACCAATAATCTTTTTTATATTTGGTTTGAATTTTTTGGTAAACCCGGCCAGTTC
TCTCTTGGTACTTTATTGTATGAACCTTACATCCAAGAGTTATTTAGAATCAACTCGGTAATGTCATGTTTGTTTTTTGT
TGCTCTGATCATGTTTTATTTTTTAAGAAATACGAATCGAATCCAAAAAGAAATGCTTCGGACAAATGCCCATAAAGATC
GTATCTTTTCCATTTTAGCACATGATTTAAAAGGACCAATTGGAACGATGAATTCTTTTTTAGGATTTTTGACAGAAACT
TTACCAGAAAGAGATGAGCTTATCATCGCACTAAAAGAATTAAAAAAAAGTACAAACCAATCTTATTTAGTTTTGGAAAA
TTTACTTGATTGGGTGAGAAATGAATCAAAAAAAAATCCAACAAATTTGGAGACTTTGAATTTGTATTCAATGATTCAAA
ATGCAAAAGATATTTTGGACTTACAGGCAACTGATAAAGGGATAGAATGGAATGTATCTGTTCCAAGCCACCTAACGGTT
TTTTGTGACGAAAGGATGATTAGCACTGTCATTCGAAATCTCTTTTCTAACGCCATCAAATTTTCTCACCCACATGGTAT
CGTTTCGATCCATGCGCATCAAAGTGGAAACTATGTGGAACTCGTCATTTCAGACTTAGGAATTGGTATGTCGAAAGAGC
AGATCAAACAAATGGAGGAAGGTAAACCTTTTCCGACCACATTTGGAACTCAAGGAGAGAAGGGAACAGGTCTTGGGCTC
CTTGTTTGTACCGAAATGCTAAAAAACCAAGGCTGTCGAATGGATGTGACAAGTTCACCTAATCAAGGTACAAAAATCAC
AATTCAAATTCCGAACTCACTGTAA

Upstream 100 bases:

>100_bases
CGTTATCTCCTAAAGAATTAAATGAAAAAATCAAAAAGGAGATCAAAAAATTTACTTTTCGATTGTCAGATGATGTAACA
TACTTTACGATCGATTTCTT

Downstream 100 bases:

>100_bases
TTTAGTTTCTTTTTTCCAGTCGATTTAGTCCAATTGGAAGGTATGTGGCCCCAAGTTTATTTTAATTGGTTACGAAACTT
CTCTCCAACTGGATCCGTTG

Product: putative two-component sensor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MKFVFNSIGIRFLLNLGVNNQLDLQTSVRVQLANLIAILGILSNIQYSILFTIAGAPYVWIMNLIHFTVVCTLSYILYLN
KKEKYVTARILLVFTISVPLLFVSFVSFGNTGGFYYYFLVFALAPFVLFSYEEKFWILFVFFTNNLFYIWFEFFGKPGQF
SLGTLLYEPYIQELFRINSVMSCLFFVALIMFYFLRNTNRIQKEMLRTNAHKDRIFSILAHDLKGPIGTMNSFLGFLTET
LPERDELIIALKELKKSTNQSYLVLENLLDWVRNESKKNPTNLETLNLYSMIQNAKDILDLQATDKGIEWNVSVPSHLTV
FCDERMISTVIRNLFSNAIKFSHPHGIVSIHAHQSGNYVELVISDLGIGMSKEQIKQMEEGKPFPTTFGTQGEKGTGLGL
LVCTEMLKNQGCRMDVTSSPNQGTKITIQIPNSL

Sequences:

>Translated_434_residues
MKFVFNSIGIRFLLNLGVNNQLDLQTSVRVQLANLIAILGILSNIQYSILFTIAGAPYVWIMNLIHFTVVCTLSYILYLN
KKEKYVTARILLVFTISVPLLFVSFVSFGNTGGFYYYFLVFALAPFVLFSYEEKFWILFVFFTNNLFYIWFEFFGKPGQF
SLGTLLYEPYIQELFRINSVMSCLFFVALIMFYFLRNTNRIQKEMLRTNAHKDRIFSILAHDLKGPIGTMNSFLGFLTET
LPERDELIIALKELKKSTNQSYLVLENLLDWVRNESKKNPTNLETLNLYSMIQNAKDILDLQATDKGIEWNVSVPSHLTV
FCDERMISTVIRNLFSNAIKFSHPHGIVSIHAHQSGNYVELVISDLGIGMSKEQIKQMEEGKPFPTTFGTQGEKGTGLGL
LVCTEMLKNQGCRMDVTSSPNQGTKITIQIPNSL
>Mature_434_residues
MKFVFNSIGIRFLLNLGVNNQLDLQTSVRVQLANLIAILGILSNIQYSILFTIAGAPYVWIMNLIHFTVVCTLSYILYLN
KKEKYVTARILLVFTISVPLLFVSFVSFGNTGGFYYYFLVFALAPFVLFSYEEKFWILFVFFTNNLFYIWFEFFGKPGQF
SLGTLLYEPYIQELFRINSVMSCLFFVALIMFYFLRNTNRIQKEMLRTNAHKDRIFSILAHDLKGPIGTMNSFLGFLTET
LPERDELIIALKELKKSTNQSYLVLENLLDWVRNESKKNPTNLETLNLYSMIQNAKDILDLQATDKGIEWNVSVPSHLTV
FCDERMISTVIRNLFSNAIKFSHPHGIVSIHAHQSGNYVELVISDLGIGMSKEQIKQMEEGKPFPTTFGTQGEKGTGLGL
LVCTEMLKNQGCRMDVTSSPNQGTKITIQIPNSL

Specific function: Kinase required for the regulation of cell division and differentiation. Makes part of a signal transduction pathway, activating pleD by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788713, Length=238, Percent_Identity=27.3109243697479, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI1790436, Length=265, Percent_Identity=23.3962264150943, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI48994928, Length=249, Percent_Identity=25.3012048192771, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1788393, Length=240, Percent_Identity=23.3333333333333, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI145693157, Length=273, Percent_Identity=23.0769230769231, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 49611; Mature: 49611

Theoretical pI: Translated: 8.42; Mature: 8.42

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFVFNSIGIRFLLNLGVNNQLDLQTSVRVQLANLIAILGILSNIQYSILFTIAGAPYVW
CCEEHHHCCHHEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHH
IMNLIHFTVVCTLSYILYLNKKEKYVTARILLVFTISVPLLFVSFVSFGNTGGFYYYFLV
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
FALAPFVLFSYEEKFWILFVFFTNNLFYIWFEFFGKPGQFSLGTLLYEPYIQELFRINSV
HHHHHHHHHCCCCCEEEEEEEHHCCEEEEEHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
MSCLFFVALIMFYFLRNTNRIQKEMLRTNAHKDRIFSILAHDLKGPIGTMNSFLGFLTET
HHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
LPERDELIIALKELKKSTNQSYLVLENLLDWVRNESKKNPTNLETLNLYSMIQNAKDILD
CCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
LQATDKGIEWNVSVPSHLTVFCDERMISTVIRNLFSNAIKFSHPHGIVSIHAHQSGNYVE
HHCCCCCCEEEEECCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEE
LVISDLGIGMSKEQIKQMEEGKPFPTTFGTQGEKGTGLGLLVCTEMLKNQGCRMDVTSSP
EEEEHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEECCCCC
NQGTKITIQIPNSL
CCCCEEEEEECCCC
>Mature Secondary Structure
MKFVFNSIGIRFLLNLGVNNQLDLQTSVRVQLANLIAILGILSNIQYSILFTIAGAPYVW
CCEEHHHCCHHEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHH
IMNLIHFTVVCTLSYILYLNKKEKYVTARILLVFTISVPLLFVSFVSFGNTGGFYYYFLV
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
FALAPFVLFSYEEKFWILFVFFTNNLFYIWFEFFGKPGQFSLGTLLYEPYIQELFRINSV
HHHHHHHHHCCCCCEEEEEEEHHCCEEEEEHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
MSCLFFVALIMFYFLRNTNRIQKEMLRTNAHKDRIFSILAHDLKGPIGTMNSFLGFLTET
HHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
LPERDELIIALKELKKSTNQSYLVLENLLDWVRNESKKNPTNLETLNLYSMIQNAKDILD
CCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
LQATDKGIEWNVSVPSHLTVFCDERMISTVIRNLFSNAIKFSHPHGIVSIHAHQSGNYVE
HHCCCCCCEEEEECCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEE
LVISDLGIGMSKEQIKQMEEGKPFPTTFGTQGEKGTGLGLLVCTEMLKNQGCRMDVTSSP
EEEEHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEECCCCC
NQGTKITIQIPNSL
CCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1438215; 11259647 [H]