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The map label for this gene is atoS [C]

Identifier: 183221821

GI number: 183221821

Start: 2531003

End: 2532940

Strand: Reverse

Name: atoS [C]

Synonym: LEPBI_I2452

Alternate gene names: 183221821

Gene position: 2532940-2531003 (Counterclockwise)

Preceding gene: 183221822

Following gene: 183221820

Centisome position: 70.37

GC content: 32.4

Gene sequence:

>1938_bases
ATGAATTCTAATATGGATTCTCAAAGAAAAATAAATGTTTTGGTTGTAGAAGATTCCGTATCCTCTTATAAGGCAATCGT
ATCAGTATTAGAAAACTTTGGATTTATCATTTCATCTGAAAGAGTGGAATGGAAAGAAGAGTTTCAAAAAAAAATATTAG
AGAAACATTGGGATATAGTAATTTCAGATTATTATTTACCAGATTTTGATGGAAAATACGTAATCCATCGCACAAAGGAA
ATTAATCCAGAGTTACCAATCATTCTTATCACTGAGTTTATTCCAGAAGAAGCAGCTTCTGAGTATTTAAATTTGGGAGC
CTCAGAATTTTTACCTAAATCATCGATCATTAAACTTCCGTTTGTTGTGAATCGTGAGTTAGAAGCTTTAAGATTAAAAC
AGTCTCAAAAAAAAGCATGGGAAATGTTAGTCCATGGTGAAGAAATTTTAACCAGGTCTCAAAAGATTTCACATCTTGGT
CATTTTGAAGTGATATTTCCAGAAAATAATACACTTTGGTCTTTAGAATTGTATCGTATACTTGGGTATGATTTCAGTGA
AGTCCCATCGATGGAAAAAGTATGGTCTTTGCTCGACGAAGTAGATAAAAAAAATATTGAAACTGTTTGGAAGGAAGTAA
CCAGTGAAAATACTTCAAAAGAGTTTGTATTTCATTTAAATACCAGGCATAGTCGTAAAAAAGTGAATTTATGGTTAGAA
GCAGAACGGTTTGATGAAAATAGATTTCGTATTTTTGGAACCATTCATGATATTTCTGATGTTTCTGATCTTGAAAGCTC
AATTCAATTAAATGAACAATTATTTAAAGGAATATTTAATAATTCATCACAAGCCATTTTCCTTTTAGATTTGCAGGGCC
ACATCATTCGTATGAATCGTAACTCTGTTTTATCGTTCGAAAGAAACGAAGCTGATGTTCAAGGCTTAGAATTGATCAGT
TCAATCTTTTCTGAATCGGATGAAGACTCGATCAAAAAATTAACATATGGTATGAAGCTTTCACTTAAGAATCAAACATT
TGAAGTGTTTGTTTCATATCGATTGCGTGATGGTCGAGAGAAGTATTTTGACTGTGATTTTTATCCTTTAAATGATCCAT
ATGGCAAAATCATATATATTGTATTAGAAGCAAAAGACATCACAGAAAAAATTGTTTTAGAAAGAGCATATGCACAGGCA
CAAAAATTAGAAGCATTGGGTACATTTGCTGGTGGGATTGCTCATGACTTTAATAATCTATTAACTCCCATGATGGCATA
TATTTCATTCTTAAATGCAGAATGGTCGAAAAATGAGTCAAATGATATGATTCAAAAGTCACTTCCGGCGATTGAAGGAA
TTTCGAAATCACTTGATCGCGCAAAAAATTTGATCCAACAAATATTAACTTATTCTAAAATAGACCACTCCTCATCCAAA
CAATTAGATTTGCGGGACCAATTGTTACAGGTTTTAAATGAGGTTAAATTTGTATCAGCAAATAAGGTTGCCCTATTTAC
TGATTTAGGAAATGAACCTGCTTATATTGATGCGGATCCAATTCAAATTTTCCAAATTCTTTCAAACTTATATGAAAATT
CACTATTTGCATTGGAAGACATTACAAATCCCAAAATTACCATCAGTCTTTCTAAAGTGACTTATGAAAAATCTGATTTG
GTCCAAGTTGGATTTATGAAGAATACAGAATATTGGAAACTCAGTTTTGCAGACAACGGGAATGGTATTCCAAAAGAAAT
TCTCGATAAAATTTTTGATCCTTTTTTTAGTACAAAAGGAGGAAAGGGGACTGGTTTGGGTCTCTCCATCATTTACGGAA
TTATGGCTAAAATGGGTGGAACGATCATGGTAGAATCAACAATTGAAAAAGGTACCCGGTTTGATCTATATTTCCCTGCA
TGGAAGGCAATGGTTTAA

Upstream 100 bases:

>100_bases
AAGGCAAGTTTGCTTTGGCAGAAGGAAGAGGAACTGCCTATAAACATAAATCTGAAATTTTAGGTGATATGGAATTACCT
ATCTTTGGTTTTTTTAATTA

Downstream 100 bases:

>100_bases
TCTATTGACAGATTCATTCATTCGATTAAGAACATAGTTTCTTATGACTTTTTTGATCCAAAAAAAACTAGAGCCATTTT
ATTTTGGTTTCCTTTGGGTT

Product: putative two-component regulator

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 645; Mature: 645

Protein sequence:

>645_residues
MNSNMDSQRKINVLVVEDSVSSYKAIVSVLENFGFIISSERVEWKEEFQKKILEKHWDIVISDYYLPDFDGKYVIHRTKE
INPELPIILITEFIPEEAASEYLNLGASEFLPKSSIIKLPFVVNRELEALRLKQSQKKAWEMLVHGEEILTRSQKISHLG
HFEVIFPENNTLWSLELYRILGYDFSEVPSMEKVWSLLDEVDKKNIETVWKEVTSENTSKEFVFHLNTRHSRKKVNLWLE
AERFDENRFRIFGTIHDISDVSDLESSIQLNEQLFKGIFNNSSQAIFLLDLQGHIIRMNRNSVLSFERNEADVQGLELIS
SIFSESDEDSIKKLTYGMKLSLKNQTFEVFVSYRLRDGREKYFDCDFYPLNDPYGKIIYIVLEAKDITEKIVLERAYAQA
QKLEALGTFAGGIAHDFNNLLTPMMAYISFLNAEWSKNESNDMIQKSLPAIEGISKSLDRAKNLIQQILTYSKIDHSSSK
QLDLRDQLLQVLNEVKFVSANKVALFTDLGNEPAYIDADPIQIFQILSNLYENSLFALEDITNPKITISLSKVTYEKSDL
VQVGFMKNTEYWKLSFADNGNGIPKEILDKIFDPFFSTKGGKGTGLGLSIIYGIMAKMGGTIMVESTIEKGTRFDLYFPA
WKAMV

Sequences:

>Translated_645_residues
MNSNMDSQRKINVLVVEDSVSSYKAIVSVLENFGFIISSERVEWKEEFQKKILEKHWDIVISDYYLPDFDGKYVIHRTKE
INPELPIILITEFIPEEAASEYLNLGASEFLPKSSIIKLPFVVNRELEALRLKQSQKKAWEMLVHGEEILTRSQKISHLG
HFEVIFPENNTLWSLELYRILGYDFSEVPSMEKVWSLLDEVDKKNIETVWKEVTSENTSKEFVFHLNTRHSRKKVNLWLE
AERFDENRFRIFGTIHDISDVSDLESSIQLNEQLFKGIFNNSSQAIFLLDLQGHIIRMNRNSVLSFERNEADVQGLELIS
SIFSESDEDSIKKLTYGMKLSLKNQTFEVFVSYRLRDGREKYFDCDFYPLNDPYGKIIYIVLEAKDITEKIVLERAYAQA
QKLEALGTFAGGIAHDFNNLLTPMMAYISFLNAEWSKNESNDMIQKSLPAIEGISKSLDRAKNLIQQILTYSKIDHSSSK
QLDLRDQLLQVLNEVKFVSANKVALFTDLGNEPAYIDADPIQIFQILSNLYENSLFALEDITNPKITISLSKVTYEKSDL
VQVGFMKNTEYWKLSFADNGNGIPKEILDKIFDPFFSTKGGKGTGLGLSIIYGIMAKMGGTIMVESTIEKGTRFDLYFPA
WKAMV
>Mature_645_residues
MNSNMDSQRKINVLVVEDSVSSYKAIVSVLENFGFIISSERVEWKEEFQKKILEKHWDIVISDYYLPDFDGKYVIHRTKE
INPELPIILITEFIPEEAASEYLNLGASEFLPKSSIIKLPFVVNRELEALRLKQSQKKAWEMLVHGEEILTRSQKISHLG
HFEVIFPENNTLWSLELYRILGYDFSEVPSMEKVWSLLDEVDKKNIETVWKEVTSENTSKEFVFHLNTRHSRKKVNLWLE
AERFDENRFRIFGTIHDISDVSDLESSIQLNEQLFKGIFNNSSQAIFLLDLQGHIIRMNRNSVLSFERNEADVQGLELIS
SIFSESDEDSIKKLTYGMKLSLKNQTFEVFVSYRLRDGREKYFDCDFYPLNDPYGKIIYIVLEAKDITEKIVLERAYAQA
QKLEALGTFAGGIAHDFNNLLTPMMAYISFLNAEWSKNESNDMIQKSLPAIEGISKSLDRAKNLIQQILTYSKIDHSSSK
QLDLRDQLLQVLNEVKFVSANKVALFTDLGNEPAYIDADPIQIFQILSNLYENSLFALEDITNPKITISLSKVTYEKSDL
VQVGFMKNTEYWKLSFADNGNGIPKEILDKIFDPFFSTKGGKGTGLGLSIIYGIMAKMGGTIMVESTIEKGTRFDLYFPA
WKAMV

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=384, Percent_Identity=27.0833333333333, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1790436, Length=241, Percent_Identity=29.4605809128631, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI145693157, Length=275, Percent_Identity=26.1818181818182, Blast_Score=77, Evalue=5e-15,
Organism=Escherichia coli, GI48994928, Length=405, Percent_Identity=25.4320987654321, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786600, Length=259, Percent_Identity=23.1660231660232, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 74183; Mature: 74183

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSNMDSQRKINVLVVEDSVSSYKAIVSVLENFGFIISSERVEWKEEFQKKILEKHWDIV
CCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHCCEE
ISDYYLPDFDGKYVIHRTKEINPELPIILITEFIPEEAASEYLNLGASEFLPKSSIIKLP
EEECCCCCCCCCEEEEECCCCCCCCCEEEEEHHCCHHHHHHHHHCCHHHCCCCCCEEECC
FVVNRELEALRLKQSQKKAWEMLVHGEEILTRSQKISHLGHFEVIFPENNTLWSLELYRI
EEECCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEECCCCCEEEEEEHHH
LGYDFSEVPSMEKVWSLLDEVDKKNIETVWKEVTSENTSKEFVFHLNTRHSRKKVNLWLE
HCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEEEEE
AERFDENRFRIFGTIHDISDVSDLESSIQLNEQLFKGIFNNSSQAIFLLDLQGHIIRMNR
EEECCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEECC
NSVLSFERNEADVQGLELISSIFSESDEDSIKKLTYGMKLSLKNQTFEVFVSYRLRDGRE
CCEEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCEEEEECCCEEEEEEEEHHCCCCC
KYFDCDFYPLNDPYGKIIYIVLEAKDITEKIVLERAYAQAQKLEALGTFAGGIAHDFNNL
CCCCCCEEECCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTPMMAYISFLNAEWSKNESNDMIQKSLPAIEGISKSLDRAKNLIQQILTYSKIDHSSSK
HHHHHHHHHHHCCCCCCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
QLDLRDQLLQVLNEVKFVSANKVALFTDLGNEPAYIDADPIQIFQILSNLYENSLFALED
CCCHHHHHHHHHHHHHEECCCCEEEEEECCCCCCEECCCHHHHHHHHHHHHHCCEEEEEC
ITNPKITISLSKVTYEKSDLVQVGFMKNTEYWKLSFADNGNGIPKEILDKIFDPFFSTKG
CCCCEEEEEEEEEEECCCCEEEEEEEECCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCC
GKGTGLGLSIIYGIMAKMGGTIMVESTIEKGTRFDLYFPAWKAMV
CCCCCHHHHHHHHHHHHCCCEEEEEEHHCCCCEEEEECCHHHHCC
>Mature Secondary Structure
MNSNMDSQRKINVLVVEDSVSSYKAIVSVLENFGFIISSERVEWKEEFQKKILEKHWDIV
CCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHCCEE
ISDYYLPDFDGKYVIHRTKEINPELPIILITEFIPEEAASEYLNLGASEFLPKSSIIKLP
EEECCCCCCCCCEEEEECCCCCCCCCEEEEEHHCCHHHHHHHHHCCHHHCCCCCCEEECC
FVVNRELEALRLKQSQKKAWEMLVHGEEILTRSQKISHLGHFEVIFPENNTLWSLELYRI
EEECCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEECCCCCEEEEEEHHH
LGYDFSEVPSMEKVWSLLDEVDKKNIETVWKEVTSENTSKEFVFHLNTRHSRKKVNLWLE
HCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEEEEE
AERFDENRFRIFGTIHDISDVSDLESSIQLNEQLFKGIFNNSSQAIFLLDLQGHIIRMNR
EEECCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEECC
NSVLSFERNEADVQGLELISSIFSESDEDSIKKLTYGMKLSLKNQTFEVFVSYRLRDGRE
CCEEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCEEEEECCCEEEEEEEEHHCCCCC
KYFDCDFYPLNDPYGKIIYIVLEAKDITEKIVLERAYAQAQKLEALGTFAGGIAHDFNNL
CCCCCCEEECCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTPMMAYISFLNAEWSKNESNDMIQKSLPAIEGISKSLDRAKNLIQQILTYSKIDHSSSK
HHHHHHHHHHHCCCCCCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
QLDLRDQLLQVLNEVKFVSANKVALFTDLGNEPAYIDADPIQIFQILSNLYENSLFALED
CCCHHHHHHHHHHHHHEECCCCEEEEEECCCCCCEECCCHHHHHHHHHHHHHCCEEEEEC
ITNPKITISLSKVTYEKSDLVQVGFMKNTEYWKLSFADNGNGIPKEILDKIFDPFFSTKG
CCCCEEEEEEEEEEECCCCEEEEEEEECCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCC
GKGTGLGLSIIYGIMAKMGGTIMVESTIEKGTRFDLYFPAWKAMV
CCCCCHHHHHHHHHHHHCCCEEEEEEHHCCCCEEEEECCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA