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The map label for this gene is ilvH [H]

Identifier: 183221732

GI number: 183221732

Start: 2431169

End: 2431657

Strand: Reverse

Name: ilvH [H]

Synonym: LEPBI_I2361

Alternate gene names: 183221732

Gene position: 2431657-2431169 (Counterclockwise)

Preceding gene: 183221733

Following gene: 183221731

Centisome position: 67.55

GC content: 42.33

Gene sequence:

>489_bases
ATGAAACATACACTCAGTATCTTAGTCAATAATCATCCAGGCGTGATGAGCCATGTCTCTGGACTTTTTACAAGACGTGG
GTATAACATTGATTCGATTGCTGTCGGAGTCACAGACAACGCAGAAGTATCTTCGATGACAATTGTTCTGAACGGGGATG
ATTTTGTTGTGGGACAAGTGAAAAACCAACTCCTCAAACTCCCCGATGTGCTTCGGGTGCAAGACATGGCCTATGCGAGT
TCTGTCCAAAGGGAACTTGTGCTTGTCTCATTTTCCATCACGGAAAACAACCGAAGTGAAGCGCTCACGATTTGTAATGG
TTTTGATGTCAAAATTTTAGAAATGACAGAAGACTCTCTTCTCATAGAATTTTCAGGAAATTCCCGTCAGGTGACAAATA
TCATCACGGTCTTAAAACCATTTGGAATTCGTGAGATCTCTCGCACTGGTCAAATTGCCATCGCCTATCGTAACCAAAAC
ACTGTTTAG

Upstream 100 bases:

>100_bases
AAGTTATGATCCCTGCGGAAGAAAAAGTATTCCCTATGATCCCTGCCGGAAAATCACAACAAGACCTCATAGAATTCAAA
GACTTGGGGAAATTGAAAAA

Downstream 100 bases:

>100_bases
AATCCTCTTGACAGTGGTCTAAAAACAAAGCATACTTGGGAACAAAACTGAGTTTGGTTCCCATGAAACGTTTTTTCACC
ATCATCGCATCCTTACTGGT

Product: acetolactate synthase 3 regulatory subunit

Products: NA

Alternate protein names: Acetohydroxy-acid synthase small subunit; AHAS; ALS [H]

Number of amino acids: Translated: 162; Mature: 162

Protein sequence:

>162_residues
MKHTLSILVNNHPGVMSHVSGLFTRRGYNIDSIAVGVTDNAEVSSMTIVLNGDDFVVGQVKNQLLKLPDVLRVQDMAYAS
SVQRELVLVSFSITENNRSEALTICNGFDVKILEMTEDSLLIEFSGNSRQVTNIITVLKPFGIREISRTGQIAIAYRNQN
TV

Sequences:

>Translated_162_residues
MKHTLSILVNNHPGVMSHVSGLFTRRGYNIDSIAVGVTDNAEVSSMTIVLNGDDFVVGQVKNQLLKLPDVLRVQDMAYAS
SVQRELVLVSFSITENNRSEALTICNGFDVKILEMTEDSLLIEFSGNSRQVTNIITVLKPFGIREISRTGQIAIAYRNQN
TV
>Mature_162_residues
MKHTLSILVNNHPGVMSHVSGLFTRRGYNIDSIAVGVTDNAEVSSMTIVLNGDDFVVGQVKNQLLKLPDVLRVQDMAYAS
SVQRELVLVSFSITENNRSEALTICNGFDVKILEMTEDSLLIEFSGNSRQVTNIITVLKPFGIREISRTGQIAIAYRNQN
TV

Specific function: Valine and isoleucine biosynthesis; first step. [C]

COG id: COG0440

COG function: function code E; Acetolactate synthase, small (regulatory) subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ACT domain [H]

Homologues:

Organism=Escherichia coli, GI1786266, Length=156, Percent_Identity=33.974358974359, Blast_Score=97, Evalue=7e-22,
Organism=Saccharomyces cerevisiae, GI6319837, Length=203, Percent_Identity=29.064039408867, Blast_Score=87, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004789
- InterPro:   IPR019455
- InterPro:   IPR002912 [H]

Pfam domain/function: PF01842 ACT; PF10369 ALS_ss_C [H]

EC number: =2.2.1.6 [H]

Molecular weight: Translated: 17885; Mature: 17885

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHTLSILVNNHPGVMSHVSGLFTRRGYNIDSIAVGVTDNAEVSSMTIVLNGDDFVVGQV
CCEEEEEEEECCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEEEEECCCCEEEEHH
KNQLLKLPDVLRVQDMAYASSVQRELVLVSFSITENNRSEALTICNGFDVKILEMTEDSL
HHHHHCCCCHHHHHHHHHHHHHCEEEEEEEEEECCCCCCCEEEEECCCCEEEEEECCCEE
LIEFSGNSRQVTNIITVLKPFGIREISRTGQIAIAYRNQNTV
EEEECCCCCCHHHHHHHHCCCCCEECCCCCCEEEEECCCCCC
>Mature Secondary Structure
MKHTLSILVNNHPGVMSHVSGLFTRRGYNIDSIAVGVTDNAEVSSMTIVLNGDDFVVGQV
CCEEEEEEEECCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEEEEECCCCEEEEHH
KNQLLKLPDVLRVQDMAYASSVQRELVLVSFSITENNRSEALTICNGFDVKILEMTEDSL
HHHHHCCCCHHHHHHHHHHHHHCEEEEEEEEEECCCCCCCEEEEECCCCEEEEEECCCEE
LIEFSGNSRQVTNIITVLKPFGIREISRTGQIAIAYRNQNTV
EEEECCCCCCHHHHHHHHCCCCCEECCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]