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The map label for this gene is gap [H]

Identifier: 183221462

GI number: 183221462

Start: 2174852

End: 2175859

Strand: Direct

Name: gap [H]

Synonym: LEPBI_I2080

Alternate gene names: 183221462

Gene position: 2174852-2175859 (Clockwise)

Preceding gene: 183221460

Following gene: 183221463

Centisome position: 60.42

GC content: 44.94

Gene sequence:

>1008_bases
ATGGTAAAAATCGCAATTAATGGTTTTGGTCGCATTGGACGACTTGTGCTTCGTTCCGGAATCAAAGATCCCAATTTAGA
ATTTGTCGCAATCAACGACCTTGTCACCCCAGACAACCTTTCTTATTTATTCAAATATGACTCTACCCATGGTCGTTTCG
ACGGAGACGTTTCTCACACAGACAACGAAATCATCATCGATGGCAAAAAAGTAAAAACTTTCTCCGAAAGAGACCCTGAA
AAACTCCCGTGGAAAGAACTCGGAGTGGACTTTGTCATCGAATCCACAGGGCTTTTCACGGACCGAGTGGGTGCTGAAAA
ACACATCAAAGCGGGTGCCAAAAAAGTAGTGATCTCCGCTCCTGCCAAAGACAAAGACATCCCTACCTTTGTGATGGGTG
TGAACCATGAAAAATATGATTCTGCCAAAGACAATGTTGTCTCGAACGCATCTTGTACCACAAACTGCCTTGCTCCGATC
ACAAAAGTGGTCCTTGACAATTTTGGAATCGTAGAAGGTCTGATGACAACGATCCATGCGATGACAGCAACCCAACCAAC
CGTTGACGGACCTTCCAAAAAAGACTTCCGTGGTGGACGTGGGGCAGCTCAAAACATCATCCCTGCCTCCACAGGGGCTG
CCAAAGCAGTAGGACTTTGTATCCCAGAAGTGAATGGAAAACTCACTGGGATGAGTTTCCGGGTTCCCACTCCCGACGTA
TCGGTTGTGGACTTAACCGTTCGCACCGAAAAACCAACTAGCCTCGCTGAAATCAAAAAGAAAATGAAAGAAGCAAGTGA
AGGTTCCATGAAAGGAATCCTTGGTTATACGGAAGACATGGTGGTTTCGAACGACTTCCTTGGTGACATTCGTTCTTCTA
TTTTTGATGCGGATGCTTGTATTGAACTAAGCCCTACTTTTTTCAAACTCGTATCTTGGTATGACAATGAAATGGGATAC
TCCAACCGAGTCCTCGACCTAGTTCGTTATATGGCAAAAAAAGGCTAA

Upstream 100 bases:

>100_bases
CACCTTCTCCTTTTAAAATGAGTGACATAGACCCCGAACTCGAAATTCTGTAATTAAAAAATCGTTTTATCTCTAGATAC
GAGCCTTTTAGGAGAAACTC

Downstream 100 bases:

>100_bases
GATGAAATTACCTCTTCTCGAAGAACAAAATCTAAAAGGAAAACGAGTCTTTGTTCGTGTGGATTTCAATGTCCCTGTGG
AAAACGGAAAAGCAACGGAC

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MVKIAINGFGRIGRLVLRSGIKDPNLEFVAINDLVTPDNLSYLFKYDSTHGRFDGDVSHTDNEIIIDGKKVKTFSERDPE
KLPWKELGVDFVIESTGLFTDRVGAEKHIKAGAKKVVISAPAKDKDIPTFVMGVNHEKYDSAKDNVVSNASCTTNCLAPI
TKVVLDNFGIVEGLMTTIHAMTATQPTVDGPSKKDFRGGRGAAQNIIPASTGAAKAVGLCIPEVNGKLTGMSFRVPTPDV
SVVDLTVRTEKPTSLAEIKKKMKEASEGSMKGILGYTEDMVVSNDFLGDIRSSIFDADACIELSPTFFKLVSWYDNEMGY
SNRVLDLVRYMAKKG

Sequences:

>Translated_335_residues
MVKIAINGFGRIGRLVLRSGIKDPNLEFVAINDLVTPDNLSYLFKYDSTHGRFDGDVSHTDNEIIIDGKKVKTFSERDPE
KLPWKELGVDFVIESTGLFTDRVGAEKHIKAGAKKVVISAPAKDKDIPTFVMGVNHEKYDSAKDNVVSNASCTTNCLAPI
TKVVLDNFGIVEGLMTTIHAMTATQPTVDGPSKKDFRGGRGAAQNIIPASTGAAKAVGLCIPEVNGKLTGMSFRVPTPDV
SVVDLTVRTEKPTSLAEIKKKMKEASEGSMKGILGYTEDMVVSNDFLGDIRSSIFDADACIELSPTFFKLVSWYDNEMGY
SNRVLDLVRYMAKKG
>Mature_335_residues
MVKIAINGFGRIGRLVLRSGIKDPNLEFVAINDLVTPDNLSYLFKYDSTHGRFDGDVSHTDNEIIIDGKKVKTFSERDPE
KLPWKELGVDFVIESTGLFTDRVGAEKHIKAGAKKVVISAPAKDKDIPTFVMGVNHEKYDSAKDNVVSNASCTTNCLAPI
TKVVLDNFGIVEGLMTTIHAMTATQPTVDGPSKKDFRGGRGAAQNIIPASTGAAKAVGLCIPEVNGKLTGMSFRVPTPDV
SVVDLTVRTEKPTSLAEIKKKMKEASEGSMKGILGYTEDMVVSNDFLGDIRSSIFDADACIELSPTFFKLVSWYDNEMGY
SNRVLDLVRYMAKKG

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=334, Percent_Identity=61.0778443113772, Blast_Score=417, Evalue=1e-117,
Organism=Homo sapiens, GI7657116, Length=329, Percent_Identity=58.3586626139818, Blast_Score=404, Evalue=1e-113,
Organism=Escherichia coli, GI1788079, Length=332, Percent_Identity=63.2530120481928, Blast_Score=437, Evalue=1e-124,
Organism=Escherichia coli, GI1789295, Length=335, Percent_Identity=39.4029850746269, Blast_Score=251, Evalue=7e-68,
Organism=Caenorhabditis elegans, GI17534677, Length=338, Percent_Identity=64.2011834319527, Blast_Score=445, Evalue=1e-125,
Organism=Caenorhabditis elegans, GI17534679, Length=338, Percent_Identity=63.6094674556213, Blast_Score=443, Evalue=1e-125,
Organism=Caenorhabditis elegans, GI32566163, Length=337, Percent_Identity=63.7982195845697, Blast_Score=441, Evalue=1e-124,
Organism=Caenorhabditis elegans, GI17568413, Length=337, Percent_Identity=63.7982195845697, Blast_Score=441, Evalue=1e-124,
Organism=Saccharomyces cerevisiae, GI6321631, Length=334, Percent_Identity=65.8682634730539, Blast_Score=446, Evalue=1e-126,
Organism=Saccharomyces cerevisiae, GI6322468, Length=334, Percent_Identity=65.5688622754491, Blast_Score=445, Evalue=1e-126,
Organism=Saccharomyces cerevisiae, GI6322409, Length=334, Percent_Identity=64.0718562874251, Blast_Score=439, Evalue=1e-124,
Organism=Drosophila melanogaster, GI17933600, Length=335, Percent_Identity=61.7910447761194, Blast_Score=407, Evalue=1e-114,
Organism=Drosophila melanogaster, GI18110149, Length=335, Percent_Identity=61.7910447761194, Blast_Score=407, Evalue=1e-114,
Organism=Drosophila melanogaster, GI85725000, Length=335, Percent_Identity=61.7910447761194, Blast_Score=407, Evalue=1e-114,
Organism=Drosophila melanogaster, GI22023983, Length=335, Percent_Identity=61.7910447761194, Blast_Score=407, Evalue=1e-114,
Organism=Drosophila melanogaster, GI19922412, Length=331, Percent_Identity=56.4954682779456, Blast_Score=372, Evalue=1e-103,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 36479; Mature: 36479

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKIAINGFGRIGRLVLRSGIKDPNLEFVAINDLVTPDNLSYLFKYDSTHGRFDGDVSHT
CEEEEECCCHHHHHHHHHCCCCCCCEEEEEEECEECCCCCEEEEEECCCCCCCCCCCCCC
DNEIIIDGKKVKTFSERDPEKLPWKELGVDFVIESTGLFTDRVGAEKHIKAGAKKVVISA
CCEEEEECCEEECCCCCCCCCCCHHHCCEEEEEECCCCCHHHCCCHHHHHCCCCEEEEEC
PAKDKDIPTFVMGVNHEKYDSAKDNVVSNASCTTNCLAPITKVVLDNFGIVEGLMTTIHA
CCCCCCCCEEEEECCCHHCCCCHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHH
MTATQPTVDGPSKKDFRGGRGAAQNIIPASTGAAKAVGLCIPEVNGKLTGMSFRVPTPDV
HHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCEEECEEEECCCCCC
SVVDLTVRTEKPTSLAEIKKKMKEASEGSMKGILGYTEDMVVSNDFLGDIRSSIFDADAC
EEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHEECCHHHHHHHHHHCCCCCE
IELSPTFFKLVSWYDNEMGYSNRVLDLVRYMAKKG
EECCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVKIAINGFGRIGRLVLRSGIKDPNLEFVAINDLVTPDNLSYLFKYDSTHGRFDGDVSHT
CEEEEECCCHHHHHHHHHCCCCCCCEEEEEEECEECCCCCEEEEEECCCCCCCCCCCCCC
DNEIIIDGKKVKTFSERDPEKLPWKELGVDFVIESTGLFTDRVGAEKHIKAGAKKVVISA
CCEEEEECCEEECCCCCCCCCCCHHHCCEEEEEECCCCCHHHCCCHHHHHCCCCEEEEEC
PAKDKDIPTFVMGVNHEKYDSAKDNVVSNASCTTNCLAPITKVVLDNFGIVEGLMTTIHA
CCCCCCCCEEEEECCCHHCCCCHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHH
MTATQPTVDGPSKKDFRGGRGAAQNIIPASTGAAKAVGLCIPEVNGKLTGMSFRVPTPDV
HHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCEEECEEEECCCCCC
SVVDLTVRTEKPTSLAEIKKKMKEASEGSMKGILGYTEDMVVSNDFLGDIRSSIFDADAC
EEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHEECCHHHHHHHHHHCCCCCE
IELSPTFFKLVSWYDNEMGYSNRVLDLVRYMAKKG
EECCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8378350 [H]