Click here to switch to the map view.

The map label for this gene is ompR [H]

Identifier: 183221309

GI number: 183221309

Start: 2014226

End: 2015353

Strand: Reverse

Name: ompR [H]

Synonym: LEPBI_I1926

Alternate gene names: 183221309

Gene position: 2015353-2014226 (Counterclockwise)

Preceding gene: 183221310

Following gene: 183221308

Centisome position: 55.99

GC content: 38.21

Gene sequence:

>1128_bases
ATGGAACCGAAGGATAGCCAACATACAATTCTCATTGTAGACGATGTTCCAGAAAATGTGGAACTACTCAAATACCTTTT
GTTACAGGAAGGATTCAAAACCTATACCGCCTATTCAGCGGAAGAAGCAAGACTCGTACTCCTAAACACATCAATCGACA
CACTCCTACTGGATGTGAATATGCCAGAACAGGATGGATTTTCGTTTTGTCGAGAATTAAGAACGATGGATCAATTCAAA
CTGCTTCCTATACTTTTTATCACTTCTATTGACCGGGAAGTGGGTTTCCAAGAAGCGATGAAAAATGGTGGTGATGATTT
TATCAATAAACCATTTAACAAACGAGAGTTAGTCGCAAAGATCCATTCTGTAATTCGATTAAAAGACCTGCAAGACGAAC
TATACCAACAAAAAAGTAAATACGAAAAAGAATTACAAACGGCAAGACGTGTCCAAGACCAACTCATCCCAGAAAAAAGT
TTCATTTGGAATGGGATAAAGGCCCAAACCTTATTCCATCCCTATTTACAAATTGGTGGGGATTTTGTGGATACTTGGAT
CGAAGAAAAAAAACTTCATATCGTCATCGCGGATTGTTCAGGGCATGGACCGAGTGCTGCTCTCATCGGGGCAATGTTTA
AAATGCAACTTTTTAACTTAGTGGCCAATATGGGTCTGAAAGAACGAGTTTCTCATTTAAGAAAGAATATGGAGCTTGTG
TTACCTGAAGATTATGCAATTACATTTTGTTATGCGATCATAGATCCAGATTTAAATTTATCTTATATCAATGGGGGACA
CCCAGCTCCTATCATTTATTTGGATGGCGAGACCAAGTTACTCAAAGGTATGAGCCCGATGATTATGGGGATCAATATGA
TTACAAATGATGAAGTACAATCTGTTTCCTTAAAACAAGGATCCAAGTTTTTTATGTACACGGATGGGGCAAGTGAAGCA
ATGAATGCAAATATGGAATATATAACGGAAGAAGGGATGCGAGATATTTTTCACGAGTCTGTAGTATCTGGAGGGGATAT
CCTTCCCACTGTTCAAAATAAAATTTTAGAGTTTTGTGGGGTTTCTACTCCTAGTGATGATATGGCAATGGTGTGTATCC
AATTATGA

Upstream 100 bases:

>100_bases
TTATCATTTTTTGTTTTTGTTTTTATTTCTACTTTCGAATCGAAACGAAAAGATCCAAGAACTGAAAAATACTCTTAGGT
CTGAATTGAATTAATCTTCT

Downstream 100 bases:

>100_bases
TACCAAATCCGCATTATAAAGGTAAGGTGAGAGATGTTTATGATTTAGGGGATAAACTTTTGCTTGTTGCTACCGATCGG
ATCTCAGCCTTTGATGTTGT

Product: putative two-component regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MEPKDSQHTILIVDDVPENVELLKYLLLQEGFKTYTAYSAEEARLVLLNTSIDTLLLDVNMPEQDGFSFCRELRTMDQFK
LLPILFITSIDREVGFQEAMKNGGDDFINKPFNKRELVAKIHSVIRLKDLQDELYQQKSKYEKELQTARRVQDQLIPEKS
FIWNGIKAQTLFHPYLQIGGDFVDTWIEEKKLHIVIADCSGHGPSAALIGAMFKMQLFNLVANMGLKERVSHLRKNMELV
LPEDYAITFCYAIIDPDLNLSYINGGHPAPIIYLDGETKLLKGMSPMIMGINMITNDEVQSVSLKQGSKFFMYTDGASEA
MNANMEYITEEGMRDIFHESVVSGGDILPTVQNKILEFCGVSTPSDDMAMVCIQL

Sequences:

>Translated_375_residues
MEPKDSQHTILIVDDVPENVELLKYLLLQEGFKTYTAYSAEEARLVLLNTSIDTLLLDVNMPEQDGFSFCRELRTMDQFK
LLPILFITSIDREVGFQEAMKNGGDDFINKPFNKRELVAKIHSVIRLKDLQDELYQQKSKYEKELQTARRVQDQLIPEKS
FIWNGIKAQTLFHPYLQIGGDFVDTWIEEKKLHIVIADCSGHGPSAALIGAMFKMQLFNLVANMGLKERVSHLRKNMELV
LPEDYAITFCYAIIDPDLNLSYINGGHPAPIIYLDGETKLLKGMSPMIMGINMITNDEVQSVSLKQGSKFFMYTDGASEA
MNANMEYITEEGMRDIFHESVVSGGDILPTVQNKILEFCGVSTPSDDMAMVCIQL
>Mature_375_residues
MEPKDSQHTILIVDDVPENVELLKYLLLQEGFKTYTAYSAEEARLVLLNTSIDTLLLDVNMPEQDGFSFCRELRTMDQFK
LLPILFITSIDREVGFQEAMKNGGDDFINKPFNKRELVAKIHSVIRLKDLQDELYQQKSKYEKELQTARRVQDQLIPEKS
FIWNGIKAQTLFHPYLQIGGDFVDTWIEEKKLHIVIADCSGHGPSAALIGAMFKMQLFNLVANMGLKERVSHLRKNMELV
LPEDYAITFCYAIIDPDLNLSYINGGHPAPIIYLDGETKLLKGMSPMIMGINMITNDEVQSVSLKQGSKFFMYTDGASEA
MNANMEYITEEGMRDIFHESVVSGGDILPTVQNKILEFCGVSTPSDDMAMVCIQL

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: COG3706

COG function: function code T; Response regulator containing a CheY-like receiver domain and a GGDEF domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=119, Percent_Identity=37.8151260504202, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI1788394, Length=131, Percent_Identity=32.0610687022901, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1787229, Length=141, Percent_Identity=31.9148936170213, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1790860, Length=124, Percent_Identity=33.0645161290323, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI2367329, Length=117, Percent_Identity=43.5897435897436, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1790863, Length=116, Percent_Identity=32.7586206896552, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1786599, Length=117, Percent_Identity=31.6239316239316, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 42517; Mature: 42517

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPKDSQHTILIVDDVPENVELLKYLLLQEGFKTYTAYSAEEARLVLLNTSIDTLLLDVN
CCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCHHHEECCCCCCEEEEEECCCCEEEEECC
MPEQDGFSFCRELRTMDQFKLLPILFITSIDREVGFQEAMKNGGDDFINKPFNKRELVAK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCHHHHHHCCCCHHHCCCCCHHHHHHH
IHSVIRLKDLQDELYQQKSKYEKELQTARRVQDQLIPEKSFIWNGIKAQTLFHPYLQIGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHCC
DFVDTWIEEKKLHIVIADCSGHGPSAALIGAMFKMQLFNLVANMGLKERVSHLRKNMELV
HHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCEEE
LPEDYAITFCYAIIDPDLNLSYINGGHPAPIIYLDGETKLLKGMSPMIMGINMITNDEVQ
CCCCCEEEEEEEEECCCCCEEEECCCCCCEEEEECCCHHHHHCCCCHHEEEEEECCCCHH
SVSLKQGSKFFMYTDGASEAMNANMEYITEEGMRDIFHESVVSGGDILPTVQNKILEFCG
EEHHCCCCEEEEEECCCHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHC
VSTPSDDMAMVCIQL
CCCCCCCCEEEEEEC
>Mature Secondary Structure
MEPKDSQHTILIVDDVPENVELLKYLLLQEGFKTYTAYSAEEARLVLLNTSIDTLLLDVN
CCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCHHHEECCCCCCEEEEEECCCCEEEEECC
MPEQDGFSFCRELRTMDQFKLLPILFITSIDREVGFQEAMKNGGDDFINKPFNKRELVAK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCHHHHHHCCCCHHHCCCCCHHHHHHH
IHSVIRLKDLQDELYQQKSKYEKELQTARRVQDQLIPEKSFIWNGIKAQTLFHPYLQIGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHCC
DFVDTWIEEKKLHIVIADCSGHGPSAALIGAMFKMQLFNLVANMGLKERVSHLRKNMELV
HHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCEEE
LPEDYAITFCYAIIDPDLNLSYINGGHPAPIIYLDGETKLLKGMSPMIMGINMITNDEVQ
CCCCCEEEEEEEEECCCCCEEEECCCCCCEEEEECCCHHHHHCCCCHHEEEEEECCCCHH
SVSLKQGSKFFMYTDGASEAMNANMEYITEEGMRDIFHESVVSGGDILPTVQNKILEFCG
EEHHCCCCEEEEEECCCHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHC
VSTPSDDMAMVCIQL
CCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]