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The map label for this gene is pepN [H]

Identifier: 183221264

GI number: 183221264

Start: 1971607

End: 1974186

Strand: Reverse

Name: pepN [H]

Synonym: LEPBI_I1880

Alternate gene names: 183221264

Gene position: 1974186-1971607 (Counterclockwise)

Preceding gene: 183221265

Following gene: 183221260

Centisome position: 54.84

GC content: 38.33

Gene sequence:

>2580_bases
ATGACTTCATCCTCTCCCTCTCCTGTTCATAAAATAGAAGAATACTCCCCAAACCTTTGGCTCACGCCAAAGGTGGATTT
GCGTTTTGATTTAGACCCTCACCTCACAGTTGTCAGAGCCGACTACGATGTACAATTAAACGGCAATTCGCCTGGTCCTT
TGTTTTTACATGGCGAAAATTTGGAATTTTTATCCTTACGACTGAATGGGGCCATTGTGGATCCCTCTGAATTTGAGATC
CAAGAATTAGGAATTTTGATCTACCATCCTCCCAGTTCAAAGTTCCAACTCACCATCGAGAATCGAATTTGCCCTTCCAA
AAATTCTTCGTTGGAAGGTTTGTACCAGTCCGGCTCTATGTTATGTACACAGAATGAGCCAGAAGGGTTTCGAAAGATCG
TTTATGCCATTGATCGACCTGATAATATGATGCAATTTGTTGTCACAATTTCAGGGGACCCAAGTTTATTTCCTGTTATG
TTATCGAATGGAAATCTGGTTTATGAAAAAATTCTTTCTGATGGGAAAAAAGAAGTAAAATGGGAAGACCCATTCCCAAA
ACCTAGCTATTTATTTGCGTTAGTTGCAGGTGAATTGGTAGAAACCATCGATTCGTTTCAAACAAAATCAGGCAGAAATG
TAACACTTAAGATATTTGTCGAAAAGGGAAATGAAAAGAAGGTGAGTTTTGCTTTTGAATCATTGAAAAAAGCAATGAAA
TGGGATGAAGATACTTTTGGTTTGGAGTATGATTTAGATCTATTTATGATTGTGGCTGTCGAAGATTTTAACATGGGGGC
CATGGAGAACAAAGGATTAAATCTTTTTAACGCAAAACTTGTCTTAGCTGACAAAAAATCGGCCACAGATGAAACCTTTG
AATCGATCTTAGCAGTCATTGGTCATGAATACTTTCACAACTGGACTGGGAATCGAGTCACCTTACGTAACTGGTTCAAT
TTAACTCTAAAAGAAGGTCTCACTGTGTTTCGTGACCAATGGTTCACGGAAGATATGACAGACCCAGCGGTCAAACGTAT
CAAAGATATTTTATTTTTGAAAGAACACCAATTTCCTGAAGACCAAGGTCCCATGTCACATCCCATTGTACCTAAATCCT
ATACGGAAATGAATAATTTTTACACAGTCACAGTATATGAAAAAGGCGCAGAAGTCATTCGGTTGGTTTCGGAGATATTG
GGAAGGGAGACATTTAAAAAAGGGTTAATGGATTATCTGACGCGTTATGATGGACAAGGTGTAACCTTTGAAGAATTCAT
ATCTTCGATGGAAGCTGCTTTCGGTAAACCCATTCCCAATATACGTAATTGGTACCATCGGAGTGGAACTCCCAAACTCC
AAGTCAAAGAAACATATGATCCAAAGTCCAATGAATGGGAATTTTCTATCAAAGACAGTTCGCAAAAAGACTTACCTCTT
ATTTTTGTGAATTCGTATGCTTGTTTTGATTCAAATGGAACCCTTTTGGCGGAAGGAAAACGAATCCAAGAGGGACATGA
GGATCAGATTCGGATGAGGGCAATTGACCCATCTGGAAACAAACCCATTGTTTCTTTCTTCCGTGGATTATCGAGTCCCA
TATTACTGGAAACAAAATTGGCAAAAGAGGAGATACGAGTTCTCGCCGAAAATGAACCAGATGGTGTCTCCCGTTTTTTT
AACTTCCAAAATCTAATCTTTTTGTGGATGGAAGAATCGATACGAAGTGGTAAGAGTGAAGATCTTACTCGTCTTTTGGA
GACCTTGGGTTCGGGATTCAAAAAGGATTGGGATAAAACATATTTTAGTTTTTATCTGACATTTCCTTCTTTGAACCAAA
TTTCAGAACAACTCCAATGTTTTGATTTTTTAAAAATGGAAACTCTTCGAAAGGAAGCAATTAGAAACATTGCGACAAAG
TTTACCAAAGAATTTCAGATATTGTATGAAGAAAATCGTAAAACCATACCGATCCAAACTAAGGAAGAGATTGGAAAAAG
AAGGTTAAAAAATACAGCACTCTATTATCTTTTACACGACCCAAGTCATCGTTTTGAAGGATTGGCTGTGGCACAACAAA
GAGAAGCAAAACACATGAGTGAGGAAATCTCGGCACTTCGTTACTTAATTGAAATTGGATCTAAGGAAAAGGAAAATGGA
ATATCCCTATTTTATGATCGTTGGAAGGAAGACGCATTAGTTCTTGATGTTTGGTTTGCCGCACAAGTAGGCACTGGGGA
AAACCGCTTCGAAGAATTGGAAATCCTGGAAACCCATCCAAAGTTTTTCATCAAGAATCCGAATAAGGTAAGGTCTTTGT
ACTTTAGTTTTGCAAGAAATCCCTTATCGTTTCATTCCAAGTCTGGAAAAGGTTACCAAATCATTGCCGAACGAATCAAA
CAATTGAATGTTATCAATCCTCAAATTGCTGCAGGTTTGGCGAAATTGTTTTCTTCGGCTTCCAAACAAAATGGAGACCT
GCCAAGAATCGCAAAACGAGAATTAGAAGATATACAAAACCTCCCCAATCTATCAAAAGACCTAGGGGAGGTAGTCGGAA
AAATCATCAATTCTTTTTAG

Upstream 100 bases:

>100_bases
ATGGTCGCAACCTCAAAGTCACCTTCGCTGAAGACAAAAGAAAAGAAAAACAGAACTAAAATTCACTTTTCTTACCAAGA
CCACCAAATAAAGAAGGAGG

Downstream 100 bases:

>100_bases
TTGTACATGGACTTGATTAAATCTTTGTATTTATCATGGATGATGTTTCGTTTCATTTTGAAAAGGTTGGTGAGTTCATC
TCCAACCTCCATGGCTTTCG

Product: aminopeptidase N

Products: NA

Alternate protein names: Alpha-aminoacylpeptide hydrolase [H]

Number of amino acids: Translated: 859; Mature: 858

Protein sequence:

>859_residues
MTSSSPSPVHKIEEYSPNLWLTPKVDLRFDLDPHLTVVRADYDVQLNGNSPGPLFLHGENLEFLSLRLNGAIVDPSEFEI
QELGILIYHPPSSKFQLTIENRICPSKNSSLEGLYQSGSMLCTQNEPEGFRKIVYAIDRPDNMMQFVVTISGDPSLFPVM
LSNGNLVYEKILSDGKKEVKWEDPFPKPSYLFALVAGELVETIDSFQTKSGRNVTLKIFVEKGNEKKVSFAFESLKKAMK
WDEDTFGLEYDLDLFMIVAVEDFNMGAMENKGLNLFNAKLVLADKKSATDETFESILAVIGHEYFHNWTGNRVTLRNWFN
LTLKEGLTVFRDQWFTEDMTDPAVKRIKDILFLKEHQFPEDQGPMSHPIVPKSYTEMNNFYTVTVYEKGAEVIRLVSEIL
GRETFKKGLMDYLTRYDGQGVTFEEFISSMEAAFGKPIPNIRNWYHRSGTPKLQVKETYDPKSNEWEFSIKDSSQKDLPL
IFVNSYACFDSNGTLLAEGKRIQEGHEDQIRMRAIDPSGNKPIVSFFRGLSSPILLETKLAKEEIRVLAENEPDGVSRFF
NFQNLIFLWMEESIRSGKSEDLTRLLETLGSGFKKDWDKTYFSFYLTFPSLNQISEQLQCFDFLKMETLRKEAIRNIATK
FTKEFQILYEENRKTIPIQTKEEIGKRRLKNTALYYLLHDPSHRFEGLAVAQQREAKHMSEEISALRYLIEIGSKEKENG
ISLFYDRWKEDALVLDVWFAAQVGTGENRFEELEILETHPKFFIKNPNKVRSLYFSFARNPLSFHSKSGKGYQIIAERIK
QLNVINPQIAAGLAKLFSSASKQNGDLPRIAKRELEDIQNLPNLSKDLGEVVGKIINSF

Sequences:

>Translated_859_residues
MTSSSPSPVHKIEEYSPNLWLTPKVDLRFDLDPHLTVVRADYDVQLNGNSPGPLFLHGENLEFLSLRLNGAIVDPSEFEI
QELGILIYHPPSSKFQLTIENRICPSKNSSLEGLYQSGSMLCTQNEPEGFRKIVYAIDRPDNMMQFVVTISGDPSLFPVM
LSNGNLVYEKILSDGKKEVKWEDPFPKPSYLFALVAGELVETIDSFQTKSGRNVTLKIFVEKGNEKKVSFAFESLKKAMK
WDEDTFGLEYDLDLFMIVAVEDFNMGAMENKGLNLFNAKLVLADKKSATDETFESILAVIGHEYFHNWTGNRVTLRNWFN
LTLKEGLTVFRDQWFTEDMTDPAVKRIKDILFLKEHQFPEDQGPMSHPIVPKSYTEMNNFYTVTVYEKGAEVIRLVSEIL
GRETFKKGLMDYLTRYDGQGVTFEEFISSMEAAFGKPIPNIRNWYHRSGTPKLQVKETYDPKSNEWEFSIKDSSQKDLPL
IFVNSYACFDSNGTLLAEGKRIQEGHEDQIRMRAIDPSGNKPIVSFFRGLSSPILLETKLAKEEIRVLAENEPDGVSRFF
NFQNLIFLWMEESIRSGKSEDLTRLLETLGSGFKKDWDKTYFSFYLTFPSLNQISEQLQCFDFLKMETLRKEAIRNIATK
FTKEFQILYEENRKTIPIQTKEEIGKRRLKNTALYYLLHDPSHRFEGLAVAQQREAKHMSEEISALRYLIEIGSKEKENG
ISLFYDRWKEDALVLDVWFAAQVGTGENRFEELEILETHPKFFIKNPNKVRSLYFSFARNPLSFHSKSGKGYQIIAERIK
QLNVINPQIAAGLAKLFSSASKQNGDLPRIAKRELEDIQNLPNLSKDLGEVVGKIINSF
>Mature_858_residues
TSSSPSPVHKIEEYSPNLWLTPKVDLRFDLDPHLTVVRADYDVQLNGNSPGPLFLHGENLEFLSLRLNGAIVDPSEFEIQ
ELGILIYHPPSSKFQLTIENRICPSKNSSLEGLYQSGSMLCTQNEPEGFRKIVYAIDRPDNMMQFVVTISGDPSLFPVML
SNGNLVYEKILSDGKKEVKWEDPFPKPSYLFALVAGELVETIDSFQTKSGRNVTLKIFVEKGNEKKVSFAFESLKKAMKW
DEDTFGLEYDLDLFMIVAVEDFNMGAMENKGLNLFNAKLVLADKKSATDETFESILAVIGHEYFHNWTGNRVTLRNWFNL
TLKEGLTVFRDQWFTEDMTDPAVKRIKDILFLKEHQFPEDQGPMSHPIVPKSYTEMNNFYTVTVYEKGAEVIRLVSEILG
RETFKKGLMDYLTRYDGQGVTFEEFISSMEAAFGKPIPNIRNWYHRSGTPKLQVKETYDPKSNEWEFSIKDSSQKDLPLI
FVNSYACFDSNGTLLAEGKRIQEGHEDQIRMRAIDPSGNKPIVSFFRGLSSPILLETKLAKEEIRVLAENEPDGVSRFFN
FQNLIFLWMEESIRSGKSEDLTRLLETLGSGFKKDWDKTYFSFYLTFPSLNQISEQLQCFDFLKMETLRKEAIRNIATKF
TKEFQILYEENRKTIPIQTKEEIGKRRLKNTALYYLLHDPSHRFEGLAVAQQREAKHMSEEISALRYLIEIGSKEKENGI
SLFYDRWKEDALVLDVWFAAQVGTGENRFEELEILETHPKFFIKNPNKVRSLYFSFARNPLSFHSKSGKGYQIIAERIKQ
LNVINPQIAAGLAKLFSSASKQNGDLPRIAKRELEDIQNLPNLSKDLGEVVGKIINSF

Specific function: Aminopeptidase N is involved in the degradation of intracellular peptides generated by protein breakdown during normal growth as well as in response to nutrient starvation [H]

COG id: COG0308

COG function: function code E; Aminopeptidase N

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M1 family [H]

Homologues:

Organism=Homo sapiens, GI158937236, Length=367, Percent_Identity=29.4277929155313, Blast_Score=135, Evalue=2e-31,
Organism=Homo sapiens, GI132814467, Length=368, Percent_Identity=26.6304347826087, Blast_Score=125, Evalue=2e-28,
Organism=Homo sapiens, GI310123622, Length=326, Percent_Identity=28.5276073619632, Blast_Score=112, Evalue=2e-24,
Organism=Homo sapiens, GI310133497, Length=263, Percent_Identity=30.7984790874525, Blast_Score=111, Evalue=3e-24,
Organism=Homo sapiens, GI94818891, Length=316, Percent_Identity=26.8987341772152, Blast_Score=106, Evalue=9e-23,
Organism=Homo sapiens, GI94818901, Length=316, Percent_Identity=26.8987341772152, Blast_Score=106, Evalue=9e-23,
Organism=Homo sapiens, GI61742775, Length=341, Percent_Identity=24.3401759530792, Blast_Score=101, Evalue=3e-21,
Organism=Homo sapiens, GI61742777, Length=341, Percent_Identity=24.3401759530792, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI194306629, Length=434, Percent_Identity=23.963133640553, Blast_Score=99, Evalue=2e-20,
Organism=Homo sapiens, GI11641261, Length=434, Percent_Identity=23.963133640553, Blast_Score=99, Evalue=2e-20,
Organism=Homo sapiens, GI157266300, Length=442, Percent_Identity=24.6606334841629, Blast_Score=95, Evalue=3e-19,
Organism=Homo sapiens, GI194239713, Length=360, Percent_Identity=25.2777777777778, Blast_Score=84, Evalue=5e-16,
Organism=Homo sapiens, GI7019561, Length=305, Percent_Identity=26.8852459016393, Blast_Score=81, Evalue=4e-15,
Organism=Homo sapiens, GI4505029, Length=387, Percent_Identity=24.031007751938, Blast_Score=74, Evalue=6e-13,
Organism=Escherichia coli, GI1787163, Length=876, Percent_Identity=37.7853881278539, Blast_Score=593, Evalue=1e-170,
Organism=Caenorhabditis elegans, GI71989076, Length=468, Percent_Identity=27.7777777777778, Blast_Score=125, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI71989071, Length=468, Percent_Identity=27.7777777777778, Blast_Score=125, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI115533278, Length=412, Percent_Identity=26.9417475728155, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI115533276, Length=412, Percent_Identity=26.9417475728155, Blast_Score=110, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI133903840, Length=463, Percent_Identity=24.8380129589633, Blast_Score=105, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI17569221, Length=369, Percent_Identity=25.4742547425474, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17569225, Length=345, Percent_Identity=27.536231884058, Blast_Score=98, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71990873, Length=298, Percent_Identity=25.1677852348993, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI193206926, Length=498, Percent_Identity=24.0963855421687, Blast_Score=87, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI193206928, Length=498, Percent_Identity=24.0963855421687, Blast_Score=87, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI71984353, Length=357, Percent_Identity=24.0896358543417, Blast_Score=82, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71984339, Length=357, Percent_Identity=24.0896358543417, Blast_Score=82, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17565628, Length=313, Percent_Identity=23.3226837060703, Blast_Score=75, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI9755335, Length=345, Percent_Identity=32.463768115942, Blast_Score=156, Evalue=1e-38,
Organism=Saccharomyces cerevisiae, GI6321837, Length=440, Percent_Identity=27.2727272727273, Blast_Score=142, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24655252, Length=387, Percent_Identity=29.4573643410853, Blast_Score=143, Evalue=6e-34,
Organism=Drosophila melanogaster, GI24655257, Length=387, Percent_Identity=29.4573643410853, Blast_Score=143, Evalue=6e-34,
Organism=Drosophila melanogaster, GI24655274, Length=387, Percent_Identity=29.4573643410853, Blast_Score=142, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24655260, Length=387, Percent_Identity=29.4573643410853, Blast_Score=142, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24655265, Length=387, Percent_Identity=29.4573643410853, Blast_Score=142, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24655268, Length=387, Percent_Identity=29.4573643410853, Blast_Score=142, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24646516, Length=381, Percent_Identity=27.5590551181102, Blast_Score=127, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24646518, Length=381, Percent_Identity=27.5590551181102, Blast_Score=127, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24646514, Length=382, Percent_Identity=28.0104712041885, Blast_Score=125, Evalue=1e-28,
Organism=Drosophila melanogaster, GI221379089, Length=433, Percent_Identity=24.9422632794457, Blast_Score=106, Evalue=6e-23,
Organism=Drosophila melanogaster, GI24646512, Length=372, Percent_Identity=25.2688172043011, Blast_Score=103, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24646510, Length=372, Percent_Identity=25.2688172043011, Blast_Score=103, Evalue=8e-22,
Organism=Drosophila melanogaster, GI161078673, Length=323, Percent_Identity=26.0061919504644, Blast_Score=101, Evalue=2e-21,
Organism=Drosophila melanogaster, GI28571901, Length=323, Percent_Identity=26.0061919504644, Blast_Score=101, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24651025, Length=395, Percent_Identity=23.5443037974684, Blast_Score=99, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24651023, Length=395, Percent_Identity=23.5443037974684, Blast_Score=99, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24651021, Length=395, Percent_Identity=23.5443037974684, Blast_Score=99, Evalue=2e-20,
Organism=Drosophila melanogaster, GI21358341, Length=359, Percent_Identity=26.7409470752089, Blast_Score=99, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24651016, Length=295, Percent_Identity=26.7796610169492, Blast_Score=94, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24648786, Length=364, Percent_Identity=26.3736263736264, Blast_Score=93, Evalue=9e-19,
Organism=Drosophila melanogaster, GI24650973, Length=396, Percent_Identity=24.4949494949495, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI45550850, Length=396, Percent_Identity=24.4949494949495, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24648790, Length=340, Percent_Identity=26.1764705882353, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI28571792, Length=376, Percent_Identity=24.7340425531915, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI221330574, Length=342, Percent_Identity=23.0994152046784, Blast_Score=75, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24648784, Length=304, Percent_Identity=23.3552631578947, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI45550350, Length=259, Percent_Identity=25.8687258687259, Blast_Score=67, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24585062, Length=259, Percent_Identity=25.8687258687259, Blast_Score=67, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24585064, Length=259, Percent_Identity=25.8687258687259, Blast_Score=67, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24585066, Length=259, Percent_Identity=25.8687258687259, Blast_Score=67, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001930
- InterPro:   IPR014782
- InterPro:   IPR012779 [H]

Pfam domain/function: PF01433 Peptidase_M1 [H]

EC number: =3.4.11.2 [H]

Molecular weight: Translated: 98681; Mature: 98549

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSSSPSPVHKIEEYSPNLWLTPKVDLRFDLDPHLTVVRADYDVQLNGNSPGPLFLHGEN
CCCCCCCCHHHHHHCCCCEEECCCCCEEECCCCCEEEEEECEEEEECCCCCCCEEEECCC
LEFLSLRLNGAIVDPSEFEIQELGILIYHPPSSKFQLTIENRICPSKNSSLEGLYQSGSM
CEEEEEEECCEEECCCCCCHHHCCEEEECCCCCCEEEEECCCCCCCCCCCHHHHHCCCCE
LCTQNEPEGFRKIVYAIDRPDNMMQFVVTISGDPSLFPVMLSNGNLVYEKILSDGKKEVK
EEECCCCHHHHHHEEEECCCCCEEEEEEEECCCCCEEEEEECCCCEEHHHHHCCCCCCCC
WEDPFPKPSYLFALVAGELVETIDSFQTKSGRNVTLKIFVEKGNEKKVSFAFESLKKAMK
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHC
WDEDTFGLEYDLDLFMIVAVEDFNMGAMENKGLNLFNAKLVLADKKSATDETFESILAVI
CCCCCCCEEECCCEEEEEEEECCCCCCCCCCCCEEEEEEEEEECCCCCCHHHHHHHHHHH
GHEYFHNWTGNRVTLRNWFNLTLKEGLTVFRDQWFTEDMTDPAVKRIKDILFLKEHQFPE
HHHHHHCCCCCEEEEEHHEEEEHHHCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCC
DQGPMSHPIVPKSYTEMNNFYTVTVYEKGAEVIRLVSEILGRETFKKGLMDYLTRYDGQG
CCCCCCCCCCCCCHHHCCCEEEEEEECCCHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCC
VTFEEFISSMEAAFGKPIPNIRNWYHRSGTPKLQVKETYDPKSNEWEFSIKDSSQKDLPL
CCHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCEEEEECCCCCCCCEEEEECCCCCCCCCE
IFVNSYACFDSNGTLLAEGKRIQEGHEDQIRMRAIDPSGNKPIVSFFRGLSSPILLETKL
EEEEEEEEECCCCCEEECCCHHCCCCCCCEEEEEECCCCCCHHHHHHHCCCCCEEEEHHH
AKEEIRVLAENEPDGVSRFFNFQNLIFLWMEESIRSGKSEDLTRLLETLGSGFKKDWDKT
HHHHHHHCCCCCCCHHHHHHHHHHHEEEEEEHHHCCCCHHHHHHHHHHHCCCHHHHHCCE
YFSFYLTFPSLNQISEQLQCFDFLKMETLRKEAIRNIATKFTKEFQILYEENRKTIPIQT
EEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
KEEIGKRRLKNTALYYLLHDPSHRFEGLAVAQQREAKHMSEEISALRYLIEIGSKEKENG
HHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
ISLFYDRWKEDALVLDVWFAAQVGTGENRFEELEILETHPKFFIKNPNKVRSLYFSFARN
CHHHHHHCCCCEEEEEEEEEEECCCCCCHHHHHHHHHCCCCEEECCCHHHHHHHHHHHCC
PLSFHSKSGKGYQIIAERIKQLNVINPQIAAGLAKLFSSASKQNGDLPRIAKRELEDIQN
CCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHC
LPNLSKDLGEVVGKIINSF
CCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TSSSPSPVHKIEEYSPNLWLTPKVDLRFDLDPHLTVVRADYDVQLNGNSPGPLFLHGEN
CCCCCCCHHHHHHCCCCEEECCCCCEEECCCCCEEEEEECEEEEECCCCCCCEEEECCC
LEFLSLRLNGAIVDPSEFEIQELGILIYHPPSSKFQLTIENRICPSKNSSLEGLYQSGSM
CEEEEEEECCEEECCCCCCHHHCCEEEECCCCCCEEEEECCCCCCCCCCCHHHHHCCCCE
LCTQNEPEGFRKIVYAIDRPDNMMQFVVTISGDPSLFPVMLSNGNLVYEKILSDGKKEVK
EEECCCCHHHHHHEEEECCCCCEEEEEEEECCCCCEEEEEECCCCEEHHHHHCCCCCCCC
WEDPFPKPSYLFALVAGELVETIDSFQTKSGRNVTLKIFVEKGNEKKVSFAFESLKKAMK
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHC
WDEDTFGLEYDLDLFMIVAVEDFNMGAMENKGLNLFNAKLVLADKKSATDETFESILAVI
CCCCCCCEEECCCEEEEEEEECCCCCCCCCCCCEEEEEEEEEECCCCCCHHHHHHHHHHH
GHEYFHNWTGNRVTLRNWFNLTLKEGLTVFRDQWFTEDMTDPAVKRIKDILFLKEHQFPE
HHHHHHCCCCCEEEEEHHEEEEHHHCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCC
DQGPMSHPIVPKSYTEMNNFYTVTVYEKGAEVIRLVSEILGRETFKKGLMDYLTRYDGQG
CCCCCCCCCCCCCHHHCCCEEEEEEECCCHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCC
VTFEEFISSMEAAFGKPIPNIRNWYHRSGTPKLQVKETYDPKSNEWEFSIKDSSQKDLPL
CCHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCEEEEECCCCCCCCEEEEECCCCCCCCCE
IFVNSYACFDSNGTLLAEGKRIQEGHEDQIRMRAIDPSGNKPIVSFFRGLSSPILLETKL
EEEEEEEEECCCCCEEECCCHHCCCCCCCEEEEEECCCCCCHHHHHHHCCCCCEEEEHHH
AKEEIRVLAENEPDGVSRFFNFQNLIFLWMEESIRSGKSEDLTRLLETLGSGFKKDWDKT
HHHHHHHCCCCCCCHHHHHHHHHHHEEEEEEHHHCCCCHHHHHHHHHHHCCCHHHHHCCE
YFSFYLTFPSLNQISEQLQCFDFLKMETLRKEAIRNIATKFTKEFQILYEENRKTIPIQT
EEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
KEEIGKRRLKNTALYYLLHDPSHRFEGLAVAQQREAKHMSEEISALRYLIEIGSKEKENG
HHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
ISLFYDRWKEDALVLDVWFAAQVGTGENRFEELEILETHPKFFIKNPNKVRSLYFSFARN
CHHHHHHCCCCEEEEEEEEEEECCCCCCHHHHHHHHHCCCCEEECCCHHHHHHHHHHHCC
PLSFHSKSGKGYQIIAERIKQLNVINPQIAAGLAKLFSSASKQNGDLPRIAKRELEDIQN
CCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHC
LPNLSKDLGEVVGKIINSF
CCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2436977; 3549459; 8905232; 9278503; 3018440; 2869947 [H]