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The map label for this gene is crp [C]

Identifier: 183221259

GI number: 183221259

Start: 1965579

End: 1966958

Strand: Direct

Name: crp [C]

Synonym: LEPBI_I1875

Alternate gene names: 183221259

Gene position: 1965579-1966958 (Clockwise)

Preceding gene: 183221257

Following gene: 183221261

Centisome position: 54.6

GC content: 37.61

Gene sequence:

>1380_bases
ATGTCGATACTAAAGAATATGATCCATCCAAATTCTCCCTACAAACGAATCTGGGATCTATTTGTTTTTTTATGCATTAC
GTATTTTGCCATCGAAGTGCCGATTCGGCTTGTTTTCCCTCATAAATTGACCGTAGGTGTCACCCACTTTGAAAGGTTCA
TTCAAATCATTTTTGGAATTGATTTGGTTTTAAACTTTTTCACTTCCATTCTCAAAGACAGACTCGTCATTCAAAACAAA
AAAATCGTCGCGAAAACATATCTAAAGTCATGGTTTCTCATCGATTTTTTATCTGCCTTTCCATTTGACCTCTTTGGAGG
TTTTTTCTTTGAATATTTTGGAGTTACGGATAGTTTAAAAATATTGCGTCTACTAAGATCTGTTAGGGTGTTCGAACTTT
TTAAATCCCTTCGGATGCTTGCACTAGGTGCTGATTCGGAAGATCGATTTAAATTGATCGAAGTGATCAATCCCATGACC
TTTCGATTGATCTTTTTTGTGTATTGGACAAGTCTCTTTGCCCATTGGGTGGCTTGCGGTTGGATTTACTTAACGCCTGA
ATTTTTAGCAGATAAGGATATATACACTCGTTATATCAGGTCTTTATACTGGTCTGTCACCACACTGACAACCATCGGAT
ATGGAGACATCACACCTACCACCAATCCGCAAACCATTTATACAATGGGGGTGATGATCCTAGGTGTTGGAATTTATGGG
TATGTGATCGGTAATATTTCGACACTTCTCTCCAATTTAGATATTTCGCGTGTCACCTTCCAAGAAAAATTAAACACAAT
CAACTCGTTCATTAAATATAAAAAATTACCGCCGCAACTTGCCAATCGGATTCGATCCTATTACATTAACCTTTGGGAAA
ACAAACATGGAATTGATGAAACTGAAATTTGGAACCAACTTCCTTCGGGGATTAAAATCGATGTTTCGATGTTTTTACAC
AACCATCTCATTTCAGTGGTTCCTTTTTTTAAAAATGCACCAGAAGAATTGAAACGTGAGGTTGTTTTAGAATTAAAACC
TGCTTATTATATGAAGGGAGATGTGATCTTTCGGGAAGGAGATGTCCCCCATAATATGTATTTTTTATCCAAAGGTCAAG
TGGAAGTGATCAAAGAAAAAACGGGAGAATTACTCGCAACACTCAATTCCGGGTCTTTTTTTGGAGAGATGAGTCTCATT
GACGACTCCCTTCGCACAGCCACAATCAGAGCCGGTTCCTATTGTGATGTATATACTTTAAGTAAAGATGCTTTTAGCGA
AATACTTAGACACCATCCCAGTTTTGCAAAACACATCAACGTGATTGCATTGGAACGAAAACAACACCAATCCAGTTTCA
AAGAATCGGACGAATCGTAA

Upstream 100 bases:

>100_bases
AGCATATCAAACTTGTTTCCACCAGCACCACCGAACATAATCACCTCTTCTACATTTCAGGATTTTTTTTCTAAGAAAGA
ACGCAAATATAAAACTTCGG

Downstream 100 bases:

>100_bases
AGAACAACAAAGTAAATTTACAAACGAAAATTCAAAATAGAATGTTCCGGGTCAACTAAGGCAATCGTCTCATCAGCCAA
TCGATCAAAGGCATACCAAG

Product: putative cyclic-nucleotide-gated cation channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 459; Mature: 458

Protein sequence:

>459_residues
MSILKNMIHPNSPYKRIWDLFVFLCITYFAIEVPIRLVFPHKLTVGVTHFERFIQIIFGIDLVLNFFTSILKDRLVIQNK
KIVAKTYLKSWFLIDFLSAFPFDLFGGFFFEYFGVTDSLKILRLLRSVRVFELFKSLRMLALGADSEDRFKLIEVINPMT
FRLIFFVYWTSLFAHWVACGWIYLTPEFLADKDIYTRYIRSLYWSVTTLTTIGYGDITPTTNPQTIYTMGVMILGVGIYG
YVIGNISTLLSNLDISRVTFQEKLNTINSFIKYKKLPPQLANRIRSYYINLWENKHGIDETEIWNQLPSGIKIDVSMFLH
NHLISVVPFFKNAPEELKREVVLELKPAYYMKGDVIFREGDVPHNMYFLSKGQVEVIKEKTGELLATLNSGSFFGEMSLI
DDSLRTATIRAGSYCDVYTLSKDAFSEILRHHPSFAKHINVIALERKQHQSSFKESDES

Sequences:

>Translated_459_residues
MSILKNMIHPNSPYKRIWDLFVFLCITYFAIEVPIRLVFPHKLTVGVTHFERFIQIIFGIDLVLNFFTSILKDRLVIQNK
KIVAKTYLKSWFLIDFLSAFPFDLFGGFFFEYFGVTDSLKILRLLRSVRVFELFKSLRMLALGADSEDRFKLIEVINPMT
FRLIFFVYWTSLFAHWVACGWIYLTPEFLADKDIYTRYIRSLYWSVTTLTTIGYGDITPTTNPQTIYTMGVMILGVGIYG
YVIGNISTLLSNLDISRVTFQEKLNTINSFIKYKKLPPQLANRIRSYYINLWENKHGIDETEIWNQLPSGIKIDVSMFLH
NHLISVVPFFKNAPEELKREVVLELKPAYYMKGDVIFREGDVPHNMYFLSKGQVEVIKEKTGELLATLNSGSFFGEMSLI
DDSLRTATIRAGSYCDVYTLSKDAFSEILRHHPSFAKHINVIALERKQHQSSFKESDES
>Mature_458_residues
SILKNMIHPNSPYKRIWDLFVFLCITYFAIEVPIRLVFPHKLTVGVTHFERFIQIIFGIDLVLNFFTSILKDRLVIQNKK
IVAKTYLKSWFLIDFLSAFPFDLFGGFFFEYFGVTDSLKILRLLRSVRVFELFKSLRMLALGADSEDRFKLIEVINPMTF
RLIFFVYWTSLFAHWVACGWIYLTPEFLADKDIYTRYIRSLYWSVTTLTTIGYGDITPTTNPQTIYTMGVMILGVGIYGY
VIGNISTLLSNLDISRVTFQEKLNTINSFIKYKKLPPQLANRIRSYYINLWENKHGIDETEIWNQLPSGIKIDVSMFLHN
HLISVVPFFKNAPEELKREVVLELKPAYYMKGDVIFREGDVPHNMYFLSKGQVEVIKEKTGELLATLNSGSFFGEMSLID
DSLRTATIRAGSYCDVYTLSKDAFSEILRHHPSFAKHINVIALERKQHQSSFKESDES

Specific function: Cyclic nucleotide-regulated potassium channel activated by cAMP [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cyclic nucleotide-binding domain [H]

Homologues:

Organism=Homo sapiens, GI4504831, Length=466, Percent_Identity=26.8240343347639, Blast_Score=197, Evalue=2e-50,
Organism=Homo sapiens, GI27886653, Length=471, Percent_Identity=26.3269639065817, Blast_Score=195, Evalue=7e-50,
Organism=Homo sapiens, GI13540549, Length=469, Percent_Identity=25.3731343283582, Blast_Score=194, Evalue=2e-49,
Organism=Homo sapiens, GI27886648, Length=470, Percent_Identity=27.6595744680851, Blast_Score=193, Evalue=2e-49,
Organism=Homo sapiens, GI116325989, Length=462, Percent_Identity=27.0562770562771, Blast_Score=193, Evalue=3e-49,
Organism=Homo sapiens, GI22024390, Length=467, Percent_Identity=27.8372591006424, Blast_Score=192, Evalue=6e-49,
Organism=Homo sapiens, GI27437001, Length=480, Percent_Identity=26.875, Blast_Score=190, Evalue=3e-48,
Organism=Homo sapiens, GI26051273, Length=472, Percent_Identity=26.0593220338983, Blast_Score=189, Evalue=5e-48,
Organism=Homo sapiens, GI4557729, Length=472, Percent_Identity=26.0593220338983, Blast_Score=189, Evalue=6e-48,
Organism=Homo sapiens, GI27886651, Length=442, Percent_Identity=25.5656108597285, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI4885407, Length=466, Percent_Identity=28.1115879828326, Blast_Score=184, Evalue=2e-46,
Organism=Homo sapiens, GI156071470, Length=462, Percent_Identity=27.2727272727273, Blast_Score=182, Evalue=5e-46,
Organism=Homo sapiens, GI4502917, Length=422, Percent_Identity=27.7251184834123, Blast_Score=178, Evalue=8e-45,
Organism=Homo sapiens, GI120433600, Length=422, Percent_Identity=27.7251184834123, Blast_Score=178, Evalue=9e-45,
Organism=Homo sapiens, GI38327037, Length=464, Percent_Identity=26.5086206896552, Blast_Score=177, Evalue=1e-44,
Organism=Homo sapiens, GI71143141, Length=425, Percent_Identity=28.2352941176471, Blast_Score=175, Evalue=6e-44,
Organism=Homo sapiens, GI217035093, Length=425, Percent_Identity=28.2352941176471, Blast_Score=175, Evalue=7e-44,
Organism=Homo sapiens, GI42718011, Length=429, Percent_Identity=27.2727272727273, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI26051271, Length=409, Percent_Identity=25.1833740831296, Blast_Score=169, Evalue=7e-42,
Organism=Homo sapiens, GI27886646, Length=418, Percent_Identity=27.7511961722488, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI27886667, Length=462, Percent_Identity=25.5411255411255, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI82617546, Length=452, Percent_Identity=24.7787610619469, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI38569493, Length=488, Percent_Identity=23.7704918032787, Blast_Score=160, Evalue=3e-39,
Organism=Homo sapiens, GI6912446, Length=469, Percent_Identity=24.0938166311301, Blast_Score=155, Evalue=1e-37,
Organism=Homo sapiens, GI27886665, Length=330, Percent_Identity=26.3636363636364, Blast_Score=132, Evalue=9e-31,
Organism=Homo sapiens, GI116642889, Length=424, Percent_Identity=25.7075471698113, Blast_Score=132, Evalue=1e-30,
Organism=Homo sapiens, GI114205399, Length=459, Percent_Identity=24.1830065359477, Blast_Score=130, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI193205559, Length=470, Percent_Identity=24.468085106383, Blast_Score=182, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI193205557, Length=470, Percent_Identity=24.468085106383, Blast_Score=182, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI17555416, Length=470, Percent_Identity=24.468085106383, Blast_Score=182, Evalue=3e-46,
Organism=Caenorhabditis elegans, GI193205554, Length=470, Percent_Identity=24.468085106383, Blast_Score=182, Evalue=4e-46,
Organism=Caenorhabditis elegans, GI193205548, Length=470, Percent_Identity=24.468085106383, Blast_Score=182, Evalue=5e-46,
Organism=Caenorhabditis elegans, GI193205550, Length=470, Percent_Identity=24.468085106383, Blast_Score=181, Evalue=5e-46,
Organism=Caenorhabditis elegans, GI193205546, Length=470, Percent_Identity=24.468085106383, Blast_Score=181, Evalue=6e-46,
Organism=Caenorhabditis elegans, GI193205552, Length=470, Percent_Identity=24.468085106383, Blast_Score=181, Evalue=7e-46,
Organism=Caenorhabditis elegans, GI17556791, Length=414, Percent_Identity=27.7777777777778, Blast_Score=172, Evalue=4e-43,
Organism=Caenorhabditis elegans, GI71989969, Length=485, Percent_Identity=25.1546391752577, Blast_Score=165, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI71985735, Length=460, Percent_Identity=26.5217391304348, Blast_Score=158, Evalue=6e-39,
Organism=Caenorhabditis elegans, GI17559702, Length=281, Percent_Identity=28.1138790035587, Blast_Score=130, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI193207729, Length=281, Percent_Identity=28.1138790035587, Blast_Score=130, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17544220, Length=255, Percent_Identity=24.7058823529412, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17538726, Length=265, Percent_Identity=23.0188679245283, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI71988286, Length=261, Percent_Identity=21.0727969348659, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI221330263, Length=465, Percent_Identity=29.4623655913978, Blast_Score=210, Evalue=2e-54,
Organism=Drosophila melanogaster, GI85725018, Length=465, Percent_Identity=29.4623655913978, Blast_Score=209, Evalue=3e-54,
Organism=Drosophila melanogaster, GI85725022, Length=464, Percent_Identity=29.7413793103448, Blast_Score=206, Evalue=2e-53,
Organism=Drosophila melanogaster, GI221330257, Length=467, Percent_Identity=29.3361884368308, Blast_Score=204, Evalue=1e-52,
Organism=Drosophila melanogaster, GI24642070, Length=465, Percent_Identity=26.8817204301075, Blast_Score=204, Evalue=1e-52,
Organism=Drosophila melanogaster, GI116007160, Length=465, Percent_Identity=26.6666666666667, Blast_Score=203, Evalue=2e-52,
Organism=Drosophila melanogaster, GI221330259, Length=496, Percent_Identity=28.0241935483871, Blast_Score=200, Evalue=2e-51,
Organism=Drosophila melanogaster, GI85725024, Length=499, Percent_Identity=27.6553106212425, Blast_Score=197, Evalue=1e-50,
Organism=Drosophila melanogaster, GI24762524, Length=471, Percent_Identity=26.3269639065817, Blast_Score=182, Evalue=4e-46,
Organism=Drosophila melanogaster, GI17136454, Length=471, Percent_Identity=26.3269639065817, Blast_Score=182, Evalue=4e-46,
Organism=Drosophila melanogaster, GI17136946, Length=469, Percent_Identity=25.1599147121535, Blast_Score=162, Evalue=4e-40,
Organism=Drosophila melanogaster, GI45549131, Length=471, Percent_Identity=25.2653927813163, Blast_Score=160, Evalue=2e-39,
Organism=Drosophila melanogaster, GI221330552, Length=408, Percent_Identity=25.7352941176471, Blast_Score=159, Evalue=4e-39,
Organism=Drosophila melanogaster, GI45551460, Length=471, Percent_Identity=25.2653927813163, Blast_Score=159, Evalue=4e-39,
Organism=Drosophila melanogaster, GI17137122, Length=404, Percent_Identity=27.2277227722772, Blast_Score=159, Evalue=5e-39,
Organism=Drosophila melanogaster, GI221330550, Length=408, Percent_Identity=25.7352941176471, Blast_Score=157, Evalue=1e-38,
Organism=Drosophila melanogaster, GI45550482, Length=241, Percent_Identity=27.3858921161826, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI221330261, Length=136, Percent_Identity=32.3529411764706, Blast_Score=69, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR018488
- InterPro:   IPR000595
- InterPro:   IPR013099
- InterPro:   IPR003091
- InterPro:   IPR014710 [H]

Pfam domain/function: PF00027 cNMP_binding; PF07885 Ion_trans_2 [H]

EC number: NA

Molecular weight: Translated: 53342; Mature: 53211

Theoretical pI: Translated: 9.01; Mature: 9.01

Prosite motif: PS00889 CNMP_BINDING_2 ; PS50042 CNMP_BINDING_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILKNMIHPNSPYKRIWDLFVFLCITYFAIEVPIRLVFPHKLTVGVTHFERFIQIIFGI
CCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEECCEEEEHHHHHHHHHHHHHHH
DLVLNFFTSILKDRLVIQNKKIVAKTYLKSWFLIDFLSAFPFDLFGGFFFEYFGVTDSLK
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHH
ILRLLRSVRVFELFKSLRMLALGADSEDRFKLIEVINPMTFRLIFFVYWTSLFAHWVACG
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHH
WIYLTPEFLADKDIYTRYIRSLYWSVTTLTTIGYGDITPTTNPQTIYTMGVMILGVGIYG
HHEECHHHHCCHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCHHHHHHHHHHHHHHHH
YVIGNISTLLSNLDISRVTFQEKLNTINSFIKYKKLPPQLANRIRSYYINLWENKHGIDE
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCH
TEIWNQLPSGIKIDVSMFLHNHLISVVPFFKNAPEELKREVVLELKPAYYMKGDVIFREG
HHHHHHCCCCCEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEECCEEEECC
DVPHNMYFLSKGQVEVIKEKTGELLATLNSGSFFGEMSLIDDSLRTATIRAGSYCDVYTL
CCCCCEEEEECCCHHHHHHHHCCEEEEECCCCCEEEHHHHHHHHHHEEEECCCCEEEEEE
SKDAFSEILRHHPSFAKHINVIALERKQHQSSFKESDES
CHHHHHHHHHHCCCHHHHHHHEEEHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SILKNMIHPNSPYKRIWDLFVFLCITYFAIEVPIRLVFPHKLTVGVTHFERFIQIIFGI
CHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEECCEEEEHHHHHHHHHHHHHHH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CHHHHHHHHHHCCCHHHHHHHEEEHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA