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The map label for this gene is yfgC [C]

Identifier: 183221124

GI number: 183221124

Start: 1813399

End: 1814175

Strand: Reverse

Name: yfgC [C]

Synonym: LEPBI_I1738

Alternate gene names: 183221124

Gene position: 1814175-1813399 (Counterclockwise)

Preceding gene: 183221125

Following gene: 183221121

Centisome position: 50.4

GC content: 41.7

Gene sequence:

>777_bases
ATGAAAGGAATCAAAATTCTTTTGTTCATAGTATTGTCATTTGTTCAGTGTAATACTTCCCCAACCGGAAGGCGTCAAAT
TACCTTAGTTGGTGATGAAGAAATGAATGAAATGGGTGCACAGGCATTTTTAGACCTAAAATCCAAAACACCAATTGATC
CAAGACCGAATACAAATGGATATGTTAAGTGTATTGTCCAGAACCAACTCACCGTTACGAATGATACAACAGGTGTGAGT
GATTGGGAAGTGGTTGTGTTTCGCGACAACACTCCCAATGCATTTGCGTTACCTGGCGGAAAAATTGGAGTTTATACGGG
AATGTTTTCCGTTGCAAAAAACAAAGACCAACTAGCGGCTGTCATTGGACATGAAATAGGCCATGTGATTGCAAGGCATG
GAAACGAAAGGGTTTCACAAAACCAATTGACATCAGGATCTGTTAAAATTTTGGAAACACTCGGAAAACCAACTGTGGCT
GGCGCATTGGGTATGGGTGCAAAATTTGGAGTTTTGTTGCCATTTTCAAGAAAACATGAAACAGAAGCAGACTTGATTGG
GCTTGAAATAATGGCAAAGGCTGGATTTGATCCGAGAGAGAGTGTGAACCTTTGGAAAAATATGAGTGCCCTTGGGAGTG
GAAAACCAAGTGAACTTCTTTCGACTCATCCTTCTGACGAGACTAGGATGCGCCAATTGAACGAAGCCATGCCAAAAGCG
ATGGCCTTGTATGATTCAGCAGTCCAATCAGGGAAAAAACCGAACTGCAATCTGTGA

Upstream 100 bases:

>100_bases
CATACCAATGTGATGAAATCCAAGGGTATTGGTTATCAAAACCAATCCCTTTTCCTGAAATCATTCCATTTTTAGATCAG
TTTTATCAGAAGGAGAATCA

Downstream 100 bases:

>100_bases
ACCCTTTCATTCACATAATAATTTCCTTCCTGAAATTTTACAATTTCTGGATTTACCCTCCTCTAAGAGAACTCCGATCC
CTTCTTGGCCATCGGAGGTA

Product: M48 family peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MKGIKILLFIVLSFVQCNTSPTGRRQITLVGDEEMNEMGAQAFLDLKSKTPIDPRPNTNGYVKCIVQNQLTVTNDTTGVS
DWEVVVFRDNTPNAFALPGGKIGVYTGMFSVAKNKDQLAAVIGHEIGHVIARHGNERVSQNQLTSGSVKILETLGKPTVA
GALGMGAKFGVLLPFSRKHETEADLIGLEIMAKAGFDPRESVNLWKNMSALGSGKPSELLSTHPSDETRMRQLNEAMPKA
MALYDSAVQSGKKPNCNL

Sequences:

>Translated_258_residues
MKGIKILLFIVLSFVQCNTSPTGRRQITLVGDEEMNEMGAQAFLDLKSKTPIDPRPNTNGYVKCIVQNQLTVTNDTTGVS
DWEVVVFRDNTPNAFALPGGKIGVYTGMFSVAKNKDQLAAVIGHEIGHVIARHGNERVSQNQLTSGSVKILETLGKPTVA
GALGMGAKFGVLLPFSRKHETEADLIGLEIMAKAGFDPRESVNLWKNMSALGSGKPSELLSTHPSDETRMRQLNEAMPKA
MALYDSAVQSGKKPNCNL
>Mature_258_residues
MKGIKILLFIVLSFVQCNTSPTGRRQITLVGDEEMNEMGAQAFLDLKSKTPIDPRPNTNGYVKCIVQNQLTVTNDTTGVS
DWEVVVFRDNTPNAFALPGGKIGVYTGMFSVAKNKDQLAAVIGHEIGHVIARHGNERVSQNQLTSGSVKILETLGKPTVA
GALGMGAKFGVLLPFSRKHETEADLIGLEIMAKAGFDPRESVNLWKNMSALGSGKPSELLSTHPSDETRMRQLNEAMPKA
MALYDSAVQSGKKPNCNL

Specific function: Unknown

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TPR repeat [H]

Homologues:

Organism=Homo sapiens, GI21686999, Length=265, Percent_Identity=29.811320754717, Blast_Score=112, Evalue=2e-25,
Organism=Escherichia coli, GI1788840, Length=215, Percent_Identity=29.3023255813954, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI87082185, Length=220, Percent_Identity=25.9090909090909, Blast_Score=67, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6322940, Length=175, Percent_Identity=37.7142857142857, Blast_Score=115, Evalue=5e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001915
- InterPro:   IPR011716
- InterPro:   IPR011990 [H]

Pfam domain/function: PF01435 Peptidase_M48; PF07720 TPR_3 [H]

EC number: NA

Molecular weight: Translated: 27912; Mature: 27912

Theoretical pI: Translated: 8.83; Mature: 8.83

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGIKILLFIVLSFVQCNTSPTGRRQITLVGDEEMNEMGAQAFLDLKSKTPIDPRPNTNG
CCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHEECCCCCCCCCCCCCCC
YVKCIVQNQLTVTNDTTGVSDWEVVVFRDNTPNAFALPGGKIGVYTGMFSVAKNKDQLAA
EEEEEEECCEEEECCCCCCCCEEEEEEECCCCCEEECCCCCEEHHHHHHHHHCCHHHHHH
VIGHEIGHVIARHGNERVSQNQLTSGSVKILETLGKPTVAGALGMGAKFGVLLPFSRKHE
HHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHCCCCHHHHHHCCCCCCCEEECCCCCCC
TEADLIGLEIMAKAGFDPRESVNLWKNMSALGSGKPSELLSTHPSDETRMRQLNEAMPKA
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHHHHHHH
MALYDSAVQSGKKPNCNL
HHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKGIKILLFIVLSFVQCNTSPTGRRQITLVGDEEMNEMGAQAFLDLKSKTPIDPRPNTNG
CCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHEECCCCCCCCCCCCCCC
YVKCIVQNQLTVTNDTTGVSDWEVVVFRDNTPNAFALPGGKIGVYTGMFSVAKNKDQLAA
EEEEEEECCEEEECCCCCCCCEEEEEEECCCCCEEECCCCCEEHHHHHHHHHCCHHHHHH
VIGHEIGHVIARHGNERVSQNQLTSGSVKILETLGKPTVAGALGMGAKFGVLLPFSRKHE
HHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHCCCCHHHHHHCCCCCCCEEECCCCCCC
TEADLIGLEIMAKAGFDPRESVNLWKNMSALGSGKPSELLSTHPSDETRMRQLNEAMPKA
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHHHHHHH
MALYDSAVQSGKKPNCNL
HHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]