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The map label for this gene is hprK

Identifier: 183221038

GI number: 183221038

Start: 1726519

End: 1727487

Strand: Direct

Name: hprK

Synonym: LEPBI_I1651

Alternate gene names: 183221038

Gene position: 1726519-1727487 (Clockwise)

Preceding gene: 183221037

Following gene: 183221039

Centisome position: 47.96

GC content: 40.45

Gene sequence:

>969_bases
ATGCCAGTTCCTGGAATCACAGTGGAAACCATTCTCCGAGACCACGACGACTTACAATTGCAACTCGTGACTGGCGAAGT
TGGTCTTTCGAATCGAATCAATAGTGCAGAAATCAATCGGCCTGGTTTATCTCTAACTGGGTTTTTTGATTTTTTTGCCA
ATGACCGAATTCAAATTTTAGGAAAGGGAGAATGGGCCTATCTCAATTCCTTGTCAGAAGAAAAACTAGGTGAGATCACA
GATAAATTTTTTGAATTCCATCTCAATTGTATCATCTATACACATGGCAATGAACCCCAAGTTCCATTTGTGGAAAGAGC
AAAAGAGAAAGGTATCCCATTATTCAAAACAGAAATTGCCACACACCGTTTCATCACCTTGATTTCCCAAATTTTAGACA
GAGCACTCGCGCCAAGAACGATGAGGCATGGTGTTCTCATCGAAGTATTTGGAATTGGAACCTTACTCACTGGTAGGTCT
GGTGTTGGAAAAAGTGAAACAGCACTCGAACTCATCGAACGAGGCCATCGTTTAGTTGCAGATGACATGGTTGAGATCAG
GAGACTGAGCGAAAGTTATTTGATAGGGTCATGTTCTGATTTACTTCGCCACCATATGGAAATCCGAGGTCTTGGCATAC
TCAATATCAAAGATCTATTTGGTGTTGGTTCAGTAAGAGACCACAAACTGATCGAACTCATCATCAATCTAAAAGAATGG
GAAGAACAAACCTCTGGTGATTATGAACGTACAGGCATCGAACAGAGTATGGAAGAAATTTTAGGTGTCTCTGTTCCTTA
TATTGAAATCCCTGTCAAACCTGGTCGGAATATTCCCATCATCGTAGAAACGGCAGCTATGAACCAAAGGCTCCGAAAGA
TGGGAAAAAATAGCGCAAAAGAATTTTCGAATAAACTCAATACTTATATCCAGCAGAGCTCCATTGAAACAAATCCAATT
AAAGATTAG

Upstream 100 bases:

>100_bases
TATTGAAATTGCTCGTAGAACAGTGGCAAAATACCGAAAGGTTTTAAGAATCCTTCCTTCCAACGAAAGAAAGCGAATCA
GTTCGCTCAAGGGGTAAACA

Downstream 100 bases:

>100_bases
AGAAGATAGTACAGGTCTACATGCAAGGCCAGCTTCCTTATTTGTAAAGGTAGCAGCGAGTTTTCCTTGTGAAATATTTG
TGATCAAAGATGACATCGAA

Product: HPr kinase/phosphorylase

Products: NA

Alternate protein names: HPrK/P; HPr(Ser) kinase/phosphorylase

Number of amino acids: Translated: 322; Mature: 321

Protein sequence:

>322_residues
MPVPGITVETILRDHDDLQLQLVTGEVGLSNRINSAEINRPGLSLTGFFDFFANDRIQILGKGEWAYLNSLSEEKLGEIT
DKFFEFHLNCIIYTHGNEPQVPFVERAKEKGIPLFKTEIATHRFITLISQILDRALAPRTMRHGVLIEVFGIGTLLTGRS
GVGKSETALELIERGHRLVADDMVEIRRLSESYLIGSCSDLLRHHMEIRGLGILNIKDLFGVGSVRDHKLIELIINLKEW
EEQTSGDYERTGIEQSMEEILGVSVPYIEIPVKPGRNIPIIVETAAMNQRLRKMGKNSAKEFSNKLNTYIQQSSIETNPI
KD

Sequences:

>Translated_322_residues
MPVPGITVETILRDHDDLQLQLVTGEVGLSNRINSAEINRPGLSLTGFFDFFANDRIQILGKGEWAYLNSLSEEKLGEIT
DKFFEFHLNCIIYTHGNEPQVPFVERAKEKGIPLFKTEIATHRFITLISQILDRALAPRTMRHGVLIEVFGIGTLLTGRS
GVGKSETALELIERGHRLVADDMVEIRRLSESYLIGSCSDLLRHHMEIRGLGILNIKDLFGVGSVRDHKLIELIINLKEW
EEQTSGDYERTGIEQSMEEILGVSVPYIEIPVKPGRNIPIIVETAAMNQRLRKMGKNSAKEFSNKLNTYIQQSSIETNPI
KD
>Mature_321_residues
PVPGITVETILRDHDDLQLQLVTGEVGLSNRINSAEINRPGLSLTGFFDFFANDRIQILGKGEWAYLNSLSEEKLGEITD
KFFEFHLNCIIYTHGNEPQVPFVERAKEKGIPLFKTEIATHRFITLISQILDRALAPRTMRHGVLIEVFGIGTLLTGRSG
VGKSETALELIERGHRLVADDMVEIRRLSESYLIGSCSDLLRHHMEIRGLGILNIKDLFGVGSVRDHKLIELIINLKEWE
EQTSGDYERTGIEQSMEEILGVSVPYIEIPVKPGRNIPIIVETAAMNQRLRKMGKNSAKEFSNKLNTYIQQSSIETNPIK
D

Specific function: Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-pr

COG id: COG1493

COG function: function code T; Serine kinase of the HPr protein, regulates carbohydrate metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HPrK/P family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HPRK_LEPBA (B0S8M8)

Other databases:

- EMBL:   CP000777
- RefSeq:   YP_001962687.1
- ProteinModelPortal:   B0S8M8
- SMR:   B0S8M8
- GeneID:   6389239
- GenomeReviews:   CP000777_GR
- KEGG:   lbf:LBF_1601
- HOGENOM:   HBG566466
- OMA:   IHGVLVD
- ProtClustDB:   PRK05428
- BioCyc:   LBIF355278:LBF_1601-MONOMER
- HAMAP:   MF_01249
- InterPro:   IPR003755
- InterPro:   IPR011104
- InterPro:   IPR011126
- TIGRFAMs:   TIGR00679

Pfam domain/function: PF07475 Hpr_kinase_C; PF02603 Hpr_kinase_N

EC number: NA

Molecular weight: Translated: 36306; Mature: 36175

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: NA

Important sites: ACT_SITE 143-143 ACT_SITE 164-164 ACT_SITE 182-182 ACT_SITE 250-250

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVPGITVETILRDHDDLQLQLVTGEVGLSNRINSAEINRPGLSLTGFFDFFANDRIQIL
CCCCCCCHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEEE
GKGEWAYLNSLSEEKLGEITDKFFEFHLNCIIYTHGNEPQVPFVERAKEKGIPLFKTEIA
ECCCCHHHHCCCHHHHHHHHHHHHHEEEEEEEEECCCCCCCCHHHHHHHCCCCEEHHHHH
THRFITLISQILDRALAPRTMRHGVLIEVFGIGTLLTGRSGVGKSETALELIERGHRLVA
HHHHHHHHHHHHHHHHCCHHHHCCEEEEEECCHHEECCCCCCCCHHHHHHHHHCCCHHHH
DDMVEIRRLSESYLIGSCSDLLRHHMEIRGLGILNIKDLFGVGSVRDHKLIELIINLKEW
HHHHHHHHHHHHHHEECHHHHHHHHHHHHCCEEEEHHHHHCCCCCCHHHHHHHHHHHHHH
EEQTSGDYERTGIEQSMEEILGVSVPYIEIPVKPGRNIPIIVETAAMNQRLRKMGKNSAK
HHHHCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEHHHHHHHHHHHCCCHHH
EFSNKLNTYIQQSSIETNPIKD
HHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
PVPGITVETILRDHDDLQLQLVTGEVGLSNRINSAEINRPGLSLTGFFDFFANDRIQIL
CCCCCCHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEEE
GKGEWAYLNSLSEEKLGEITDKFFEFHLNCIIYTHGNEPQVPFVERAKEKGIPLFKTEIA
ECCCCHHHHCCCHHHHHHHHHHHHHEEEEEEEEECCCCCCCCHHHHHHHCCCCEEHHHHH
THRFITLISQILDRALAPRTMRHGVLIEVFGIGTLLTGRSGVGKSETALELIERGHRLVA
HHHHHHHHHHHHHHHHCCHHHHCCEEEEEECCHHEECCCCCCCCHHHHHHHHHCCCHHHH
DDMVEIRRLSESYLIGSCSDLLRHHMEIRGLGILNIKDLFGVGSVRDHKLIELIINLKEW
HHHHHHHHHHHHHHEECHHHHHHHHHHHHCCEEEEHHHHHCCCCCCHHHHHHHHHHHHHH
EEQTSGDYERTGIEQSMEEILGVSVPYIEIPVKPGRNIPIIVETAAMNQRLRKMGKNSAK
HHHHCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEHHHHHHHHHHHCCCHHH
EFSNKLNTYIQQSSIETNPIKD
HHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA