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The map label for this gene is metX [H]

Identifier: 183220979

GI number: 183220979

Start: 1668349

End: 1669485

Strand: Reverse

Name: metX [H]

Synonym: LEPBI_I1592

Alternate gene names: 183220979

Gene position: 1669485-1668349 (Counterclockwise)

Preceding gene: 183220980

Following gene: 183220978

Centisome position: 46.38

GC content: 41.25

Gene sequence:

>1137_bases
ATGCCTACTTCAGAACCAAACGATTTTTTTCATGGATCCGTAGGCATCGTACAGACTCAGGTAGCCACGTTTGACTCATT
AACACTTGAGGGGGGTGAGACCATCACTCCTCTTGAGATTGCTTATGAAACCTATGGCACTCTCAATCAAAAAAAAGACA
ATGCTATCTTAGTATGTCATGCTTTATCGGGGGATGCACATGCCGCCGGTTTCCATGAAGGTGACAAACGACCTGGTTGG
TGGGACTATTACATCGGTCCAGGGAAAGCCTTTGATACCAATCGATACTTTATCATTTCCTCAAACGTAATTGGGGGTTG
TAAAGGTTCCAGTGGCCCTTTGAGTACAAACGGGAATACGGGCAAACCATTCCAATCTACGTTTCCTTTTGTTTCCATTG
GAGATATGGTCAATGCACAGGAAAAACTAATTCGTCATTTCGGGATCCATAAACTATTTGCCGTTGCTGGCGGTTCGATG
GGTGGTATGCAAGCCTTACAATGGTCAGTTGCTTATCCTGATCGTCTGAAAAATTGTATTGTTATGGCCTCTTCCTCCGA
ACACTCAGCACAACAAATCGCATTCAATGAAGTGGGTAGACAGGCAATTTTGTCTGATCCAAATTGGAACCAAGGATTAT
ATACTCAAGAAAAACGACCATCTAAAGGATTGGCACTGGCTCGGATGATGGGTCACATAACATACCTTAGTGACGAAATG
ATGCGAGAAAAATTTGGTCGTAAACCTCCTAAAGGAAATATACAATCTACAGATTTTGCCGTTGGAAGTTATTTGATTTA
CCAAGGAGAATCTTTCGTAGACCGATTTGATGCCAATTCTTATATTTATGTAACCAAAGCTTTGGATCATTTTAGTTTGG
GAACTGGTAAGGAACTTACGAAAGTATTATCCAAAGTTAGGTGCCGATTTCTCGTGATTGCTTATACATCTGATTGGTTG
TATCCACCCTACCAATCTGAAGAAATTGTAAAATCTTTGGAAGTGAATGCGGTTCCAGTGAGTTTCATTGAATTGAATAA
CCCAGCAGGTCACGATAGTTTCCTTTTACCAAGCGAAGAGCAAGACTCAATTTTACGCGATTTTTTAAGTGCAACCGATG
AGGGAGGTTTCTTTTGA

Upstream 100 bases:

>100_bases
GTGTCACTCCTGGGTTTGTGAGACTCAGTGTCGGTTTAGAAAATCTAGACGACATTCTAGTAGACTTGGAAGAGGCATTA
AAAAATATCTGATTAAAGAC

Downstream 100 bases:

>100_bases
ACATCCATACAAATGAAACACTCGGTTTGGACTTAAAAAATAGACCAGACATTTCGTATATTGCCAATTTAATCAAACCA
GGCGAAAGAGTTTTAGATTT

Product: homoserine O-acetyltransferase

Products: NA

Alternate protein names: Homoserine O-trans-acetylase; HTA; Homoserine transacetylase [H]

Number of amino acids: Translated: 378; Mature: 377

Protein sequence:

>378_residues
MPTSEPNDFFHGSVGIVQTQVATFDSLTLEGGETITPLEIAYETYGTLNQKKDNAILVCHALSGDAHAAGFHEGDKRPGW
WDYYIGPGKAFDTNRYFIISSNVIGGCKGSSGPLSTNGNTGKPFQSTFPFVSIGDMVNAQEKLIRHFGIHKLFAVAGGSM
GGMQALQWSVAYPDRLKNCIVMASSSEHSAQQIAFNEVGRQAILSDPNWNQGLYTQEKRPSKGLALARMMGHITYLSDEM
MREKFGRKPPKGNIQSTDFAVGSYLIYQGESFVDRFDANSYIYVTKALDHFSLGTGKELTKVLSKVRCRFLVIAYTSDWL
YPPYQSEEIVKSLEVNAVPVSFIELNNPAGHDSFLLPSEEQDSILRDFLSATDEGGFF

Sequences:

>Translated_378_residues
MPTSEPNDFFHGSVGIVQTQVATFDSLTLEGGETITPLEIAYETYGTLNQKKDNAILVCHALSGDAHAAGFHEGDKRPGW
WDYYIGPGKAFDTNRYFIISSNVIGGCKGSSGPLSTNGNTGKPFQSTFPFVSIGDMVNAQEKLIRHFGIHKLFAVAGGSM
GGMQALQWSVAYPDRLKNCIVMASSSEHSAQQIAFNEVGRQAILSDPNWNQGLYTQEKRPSKGLALARMMGHITYLSDEM
MREKFGRKPPKGNIQSTDFAVGSYLIYQGESFVDRFDANSYIYVTKALDHFSLGTGKELTKVLSKVRCRFLVIAYTSDWL
YPPYQSEEIVKSLEVNAVPVSFIELNNPAGHDSFLLPSEEQDSILRDFLSATDEGGFF
>Mature_377_residues
PTSEPNDFFHGSVGIVQTQVATFDSLTLEGGETITPLEIAYETYGTLNQKKDNAILVCHALSGDAHAAGFHEGDKRPGWW
DYYIGPGKAFDTNRYFIISSNVIGGCKGSSGPLSTNGNTGKPFQSTFPFVSIGDMVNAQEKLIRHFGIHKLFAVAGGSMG
GMQALQWSVAYPDRLKNCIVMASSSEHSAQQIAFNEVGRQAILSDPNWNQGLYTQEKRPSKGLALARMMGHITYLSDEMM
REKFGRKPPKGNIQSTDFAVGSYLIYQGESFVDRFDANSYIYVTKALDHFSLGTGKELTKVLSKVRCRFLVIAYTSDWLY
PPYQSEEIVKSLEVNAVPVSFIELNNPAGHDSFLLPSEEQDSILRDFLSATDEGGFF

Specific function: Unknown

COG id: COG2021

COG function: function code E; Homoserine acetyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. HTA family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6324052, Length=237, Percent_Identity=38.8185654008439, Blast_Score=172, Evalue=5e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR008220 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =2.3.1.31 [H]

Molecular weight: Translated: 41701; Mature: 41570

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTSEPNDFFHGSVGIVQTQVATFDSLTLEGGETITPLEIAYETYGTLNQKKDNAILVCH
CCCCCCCCCCCCCCCEEEEEEHHHCEEEECCCCEECHHEEHHHHHCCCCCCCCCEEEEEE
ALSGDAHAAGFHEGDKRPGWWDYYIGPGKAFDTNRYFIISSNVIGGCKGSSGPLSTNGNT
ECCCCCCCCCCCCCCCCCCEEEEEECCCCEECCCEEEEEECCEECCCCCCCCCCCCCCCC
GKPFQSTFPFVSIGDMVNAQEKLIRHFGIHKLFAVAGGSMGGMQALQWSVAYPDRLKNCI
CCCHHHCCCEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHEEECCCHHHHCCEE
VMASSSEHSAQQIAFNEVGRQAILSDPNWNQGLYTQEKRPSKGLALARMMGHITYLSDEM
EEECCCCCHHHHHHHHHHCCCEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
MREKFGRKPPKGNIQSTDFAVGSYLIYQGESFVDRFDANSYIYVTKALDHFSLGTGKELT
HHHHHCCCCCCCCCCCCCEEECEEEEECCCHHHHHHCCCCEEEEEECCCCCCCCCCHHHH
KVLSKVRCRFLVIAYTSDWLYPPYQSEEIVKSLEVNAVPVSFIELNNPAGHDSFLLPSEE
HHHHHHCEEEEEEEEECCCCCCCCCHHHHHHHHCCCCEEEEEEEECCCCCCCCEECCCCC
QDSILRDFLSATDEGGFF
HHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
PTSEPNDFFHGSVGIVQTQVATFDSLTLEGGETITPLEIAYETYGTLNQKKDNAILVCH
CCCCCCCCCCCCCCEEEEEEHHHCEEEECCCCEECHHEEHHHHHCCCCCCCCCEEEEEE
ALSGDAHAAGFHEGDKRPGWWDYYIGPGKAFDTNRYFIISSNVIGGCKGSSGPLSTNGNT
ECCCCCCCCCCCCCCCCCCEEEEEECCCCEECCCEEEEEECCEECCCCCCCCCCCCCCCC
GKPFQSTFPFVSIGDMVNAQEKLIRHFGIHKLFAVAGGSMGGMQALQWSVAYPDRLKNCI
CCCHHHCCCEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHEEECCCHHHHCCEE
VMASSSEHSAQQIAFNEVGRQAILSDPNWNQGLYTQEKRPSKGLALARMMGHITYLSDEM
EEECCCCCHHHHHHHHHHCCCEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
MREKFGRKPPKGNIQSTDFAVGSYLIYQGESFVDRFDANSYIYVTKALDHFSLGTGKELT
HHHHHCCCCCCCCCCCCCEEECEEEEECCCHHHHHHCCCCEEEEEECCCCCCCCCCHHHH
KVLSKVRCRFLVIAYTSDWLYPPYQSEEIVKSLEVNAVPVSFIELNNPAGHDSFLLPSEE
HHHHHHCEEEEEEEEECCCCCCCCCHHHHHHHHCCCCEEEEEEEECCCCCCCCEECCCCC
QDSILRDFLSATDEGGFF
HHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9209059 [H]