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The map label for this gene is engA [H]

Identifier: 183220801

GI number: 183220801

Start: 1472451

End: 1473803

Strand: Direct

Name: engA [H]

Synonym: LEPBI_I1412

Alternate gene names: 183220801

Gene position: 1472451-1473803 (Clockwise)

Preceding gene: 183220800

Following gene: 183220802

Centisome position: 40.91

GC content: 41.61

Gene sequence:

>1353_bases
ATGAAGGGACTTCCAGTGGTCACCATTGTTGGTAGACAAAATGTGGGAAAATCCACATTATTTAACGCCATTCTCCGAGC
ACAAAGTGCGATTACCGAAAACACAGCGGGTGTTACGCGGGATGTATTACAAAAAACTGTGGAACGAGCTGAATTTAAAA
TTCCGTTCACTTTGTCCGACACTCCAGGTCTTGACATTGAAAACATTGATGAAATCTCAAAAGAAATCATAGAGATTGCC
TTTGAACATCTCCGCCATTCGGATCTCATCTTACATGTGATCGATCATAAAGACTTACGAAAGTATGACTACAAACTCAT
TGATTATTTCAAAAAAGATGAAATCTTAAAAGAGAAAAATGTCCTCACTCTCATCAACAAAGTGGATACAGAACAAGATG
AGTATGATTTGGAGCCATTTTACACACTGGGGTTAAACGAACTCCTTCCAATCTCTGCCCTTGGTCGTAGGAATTTTGAT
TTACTTTACCAAAAAATTAATTTTTTTCTCCCCGATAAAATCAAAACCCAAGAAGATCCGTATTGTAAAATTGCGATCAT
TGGAAAACCTAACTCTGGTAAGTCGTCACTTCTCAATACCTTCCTTGGTTACAAACGAGCCGTTGTGAGTGAGGTGCCAG
GTACCACTAGGGATTCCGTATCCGATCAGTTCTTTTTCCAAAACCATAAATTGGAAATCATCGATACAGCAGGGATTCGT
AGGAAATCCAAAACGGGTGAGAGTTTGGAATTTTACTCCTACAAACGAACCCTCCATAGTTTGGGGGAAGCCGATGTCGT
GGTCCTTCTCGTGGATGCCATGAAAGGACTTGGTGAATTTGACAAAAAGATCTTTGGGGAAATCCAAGAACTCGGAAAAC
CCATGATTGTGGCCGTGAACAAATGGGATTTGGTCCCGGAAAAAGAATCCAACTCTTGGAAGGATTACAAAGACAGAATG
GAAGCAAAACTCTCCATCCTAAAAGAGAGACCTCTCCTTTCCCTTTCGGCCAAAGAGAAACTCCGCACCCACAAACTCTT
GGAATCAGTGGTGGCCCTCTATGAAAAGTCCCAAAAAAAGCTAACGACCCGCCAATTAAATGACTGGTTAAGCAAGTGGG
GGGGAAAAAATAAGGTACAGAAGGCATCGAACCGACCTCCGAAGGTGTATTACGCCACTCAGGTCTCGCAGATTCCTTTT
AAAATATTGTTCTTCGTGAATGATACAAAACTCTTTCCCTCAAATATTTTGAGTTTCTACCGAAAGAGTATTGTAAAGGA
ATTTGGACTGGACGGACTTTCCGTTGAGATCGAACTCCGGAACAGAAACGAAGGAAAGGAGGGCAGGGAATGA

Upstream 100 bases:

>100_bases
CATTAGCCAAACCAAAAAAATTATACGACAAACGGGATGATATCCAAAAAAAGGAAGCCAAAATCGATATGGAAAGAGCC
ATGAAGGAACACTTACGCAA

Downstream 100 bases:

>100_bases
TTCTTGCCGCAATCCTATTCAGCTACCTTTTTGGTGGCATTCCGGTGGGGTACATCCTCACCAAACAAGTGCGAGGGATT
GACATCCGCGAGCACGGCAG

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 450; Mature: 450

Protein sequence:

>450_residues
MKGLPVVTIVGRQNVGKSTLFNAILRAQSAITENTAGVTRDVLQKTVERAEFKIPFTLSDTPGLDIENIDEISKEIIEIA
FEHLRHSDLILHVIDHKDLRKYDYKLIDYFKKDEILKEKNVLTLINKVDTEQDEYDLEPFYTLGLNELLPISALGRRNFD
LLYQKINFFLPDKIKTQEDPYCKIAIIGKPNSGKSSLLNTFLGYKRAVVSEVPGTTRDSVSDQFFFQNHKLEIIDTAGIR
RKSKTGESLEFYSYKRTLHSLGEADVVVLLVDAMKGLGEFDKKIFGEIQELGKPMIVAVNKWDLVPEKESNSWKDYKDRM
EAKLSILKERPLLSLSAKEKLRTHKLLESVVALYEKSQKKLTTRQLNDWLSKWGGKNKVQKASNRPPKVYYATQVSQIPF
KILFFVNDTKLFPSNILSFYRKSIVKEFGLDGLSVEIELRNRNEGKEGRE

Sequences:

>Translated_450_residues
MKGLPVVTIVGRQNVGKSTLFNAILRAQSAITENTAGVTRDVLQKTVERAEFKIPFTLSDTPGLDIENIDEISKEIIEIA
FEHLRHSDLILHVIDHKDLRKYDYKLIDYFKKDEILKEKNVLTLINKVDTEQDEYDLEPFYTLGLNELLPISALGRRNFD
LLYQKINFFLPDKIKTQEDPYCKIAIIGKPNSGKSSLLNTFLGYKRAVVSEVPGTTRDSVSDQFFFQNHKLEIIDTAGIR
RKSKTGESLEFYSYKRTLHSLGEADVVVLLVDAMKGLGEFDKKIFGEIQELGKPMIVAVNKWDLVPEKESNSWKDYKDRM
EAKLSILKERPLLSLSAKEKLRTHKLLESVVALYEKSQKKLTTRQLNDWLSKWGGKNKVQKASNRPPKVYYATQVSQIPF
KILFFVNDTKLFPSNILSFYRKSIVKEFGLDGLSVEIELRNRNEGKEGRE
>Mature_450_residues
MKGLPVVTIVGRQNVGKSTLFNAILRAQSAITENTAGVTRDVLQKTVERAEFKIPFTLSDTPGLDIENIDEISKEIIEIA
FEHLRHSDLILHVIDHKDLRKYDYKLIDYFKKDEILKEKNVLTLINKVDTEQDEYDLEPFYTLGLNELLPISALGRRNFD
LLYQKINFFLPDKIKTQEDPYCKIAIIGKPNSGKSSLLNTFLGYKRAVVSEVPGTTRDSVSDQFFFQNHKLEIIDTAGIR
RKSKTGESLEFYSYKRTLHSLGEADVVVLLVDAMKGLGEFDKKIFGEIQELGKPMIVAVNKWDLVPEKESNSWKDYKDRM
EAKLSILKERPLLSLSAKEKLRTHKLLESVVALYEKSQKKLTTRQLNDWLSKWGGKNKVQKASNRPPKVYYATQVSQIPF
KILFFVNDTKLFPSNILSFYRKSIVKEFGLDGLSVEIELRNRNEGKEGRE

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=456, Percent_Identity=28.7280701754386, Blast_Score=174, Evalue=7e-45,
Organism=Escherichia coli, GI2367268, Length=128, Percent_Identity=35.9375, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1788919, Length=129, Percent_Identity=32.5581395348837, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17507259, Length=124, Percent_Identity=33.0645161290323, Blast_Score=68, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323665, Length=181, Percent_Identity=30.939226519337, Blast_Score=82, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 51689; Mature: 51689

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGLPVVTIVGRQNVGKSTLFNAILRAQSAITENTAGVTRDVLQKTVERAEFKIPFTLSD
CCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHEEEEEEECC
TPGLDIENIDEISKEIIEIAFEHLRHSDLILHVIDHKDLRKYDYKLIDYFKKDEILKEKN
CCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCC
VLTLINKVDTEQDEYDLEPFYTLGLNELLPISALGRRNFDLLYQKINFFLPDKIKTQEDP
HHHHHHHHCCCCCCCCCCCCEECCCHHHCCHHHHCCCCHHHHHHHHHHCCCCCCCCCCCC
YCKIAIIGKPNSGKSSLLNTFLGYKRAVVSEVPGTTRDSVSDQFFFQNHKLEIIDTAGIR
CEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCEEEEECCCCC
RKSKTGESLEFYSYKRTLHSLGEADVVVLLVDAMKGLGEFDKKIFGEIQELGKPMIVAVN
CCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
KWDLVPEKESNSWKDYKDRMEAKLSILKERPLLSLSAKEKLRTHKLLESVVALYEKSQKK
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LTTRQLNDWLSKWGGKNKVQKASNRPPKVYYATQVSQIPFKILFFVNDTKLFPSNILSFY
HHHHHHHHHHHHCCCCCHHHHHCCCCCEEEEEEECCCCCEEEEEEEECCCCCHHHHHHHH
RKSIVKEFGLDGLSVEIELRNRNEGKEGRE
HHHHHHHHCCCCEEEEEEECCCCCCCCCCC
>Mature Secondary Structure
MKGLPVVTIVGRQNVGKSTLFNAILRAQSAITENTAGVTRDVLQKTVERAEFKIPFTLSD
CCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHEEEEEEECC
TPGLDIENIDEISKEIIEIAFEHLRHSDLILHVIDHKDLRKYDYKLIDYFKKDEILKEKN
CCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCC
VLTLINKVDTEQDEYDLEPFYTLGLNELLPISALGRRNFDLLYQKINFFLPDKIKTQEDP
HHHHHHHHCCCCCCCCCCCCEECCCHHHCCHHHHCCCCHHHHHHHHHHCCCCCCCCCCCC
YCKIAIIGKPNSGKSSLLNTFLGYKRAVVSEVPGTTRDSVSDQFFFQNHKLEIIDTAGIR
CEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCEEEEECCCCC
RKSKTGESLEFYSYKRTLHSLGEADVVVLLVDAMKGLGEFDKKIFGEIQELGKPMIVAVN
CCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
KWDLVPEKESNSWKDYKDRMEAKLSILKERPLLSLSAKEKLRTHKLLESVVALYEKSQKK
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LTTRQLNDWLSKWGGKNKVQKASNRPPKVYYATQVSQIPFKILFFVNDTKLFPSNILSFY
HHHHHHHHHHHHCCCCCHHHHHCCCCCEEEEEEECCCCCEEEEEEEECCCCCHHHHHHHH
RKSIVKEFGLDGLSVEIELRNRNEGKEGRE
HHHHHHHHCCCCEEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA