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The map label for this gene is 183220494

Identifier: 183220494

GI number: 183220494

Start: 1143052

End: 1144248

Strand: Direct

Name: 183220494

Synonym: LEPBI_I1093

Alternate gene names: NA

Gene position: 1143052-1144248 (Clockwise)

Preceding gene: 183220493

Following gene: 183220496

Centisome position: 31.75

GC content: 38.01

Gene sequence:

>1197_bases
TTGGATATTGAACTTTCGGGAATTGATTTTCCATCGGCAAATTGTCTAAAGAAAGATCATATGTCAGGAAAAAATACTTT
GCCTTCCGCTCTCGTCTCAATTTGTTTTGGTTTCATTTTAACGTTAACCTTTGTTCACTGTAAGGCATTTGGGAAAGACC
CTGAAGGTGCCCATAAAGAAAAAATCCAAAAGTCATCCCATTTTGATCCAACTCGCGAACAATTTGTCAACCGCAGACCC
GATATTTTAGAGAAGATGAGGGAAGGACAAAACTTTTTTTCCCTTTTCGTTAAGTTTATGTTTGGTGGTGACAAAAACCA
AAAACCTTCCGCGAAATTACCGGAAGAAAAACCAAACTTTAAGGAATTTTTGGAACCGGACGAAAGCATTAAATTCATTT
GGTTTGGCCATTCCACTTTCCTTGTGAATATCGAAGGCACCATTTTATTTTTTGATCCAGTTTTTTCGGAATCCGCTGCT
CCATTTAGTTTTATGGTCAAACGTTTTCAAGATGCAGTGGTCAAGTTAGAAGAAATACCAAAAGTAGATTACATCATCAT
TTCGCATGACCATTATGATCACTTGGATATGGAAACAATTGAATTTTTCAAATCAAAACAAACACGTTTCATCACACCAC
TTGGAGTCACATCTCATATAAAGGAGTGGGGTGTTTCTGAGGATCGCCTAACGGAACTTGATTGGTGGGAAAAGCTGGAT
TTGGGAAAAATTCAAATCGTTTGTACTCCTGCGCAACATTTTTCTGGGAGACGTGGGATGAATGGAAATAAAACTCTTTG
GTCTTCCTGGACCATTCTCGGACAAAAGGAACGATTTTACTTTAGTGGGGACTCAGGTTATGATATTCATTTCAAACAAA
TCGGGGAAACGTATGGACCTTTTGACCTAACTTTTATCGAAAATGGGCAATACAATCCCATGTGGGAAGCCGTTCATGTT
TTGCCTGAACAAACCGCAAAGGCCCACTTAGATTTAAAAGGGAAAGCATTGGTTCCTGTGCATTGGGGAATGTTTAATTT
ATCCTTACATAGCTGGTATGAGCCTGCCGAAAACATTGAAAGAGAAGCCAAAAAACATAACATCAATTTGTTGACACCAA
AATTCGGACAATTGGTCAAACTAAAAAATCCAAATCTCTTGGAACGTTGGTGGAAAAAATACATCGAACAAAATTAA

Upstream 100 bases:

>100_bases
AGGTTTTTACGGAATCAAAGTAAAGGAAGAAAAAAAGTGAAGTTTCCGAGATAAAAATCAGGATTTTGGTAGGAATAGGC
AAAAGAAAAATAAAAAACAA

Downstream 100 bases:

>100_bases
TGTTCGCTGTATTTAAGAATGTGTTTCGACGTACTGTTTGAAATTATTTAAAATGGACTGCCAACCATCCTTTTGCATCT
CGATTGGATTTTCATTTTCA

Product: putative zinc-dependent hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MDIELSGIDFPSANCLKKDHMSGKNTLPSALVSICFGFILTLTFVHCKAFGKDPEGAHKEKIQKSSHFDPTREQFVNRRP
DILEKMREGQNFFSLFVKFMFGGDKNQKPSAKLPEEKPNFKEFLEPDESIKFIWFGHSTFLVNIEGTILFFDPVFSESAA
PFSFMVKRFQDAVVKLEEIPKVDYIIISHDHYDHLDMETIEFFKSKQTRFITPLGVTSHIKEWGVSEDRLTELDWWEKLD
LGKIQIVCTPAQHFSGRRGMNGNKTLWSSWTILGQKERFYFSGDSGYDIHFKQIGETYGPFDLTFIENGQYNPMWEAVHV
LPEQTAKAHLDLKGKALVPVHWGMFNLSLHSWYEPAENIEREAKKHNINLLTPKFGQLVKLKNPNLLERWWKKYIEQN

Sequences:

>Translated_398_residues
MDIELSGIDFPSANCLKKDHMSGKNTLPSALVSICFGFILTLTFVHCKAFGKDPEGAHKEKIQKSSHFDPTREQFVNRRP
DILEKMREGQNFFSLFVKFMFGGDKNQKPSAKLPEEKPNFKEFLEPDESIKFIWFGHSTFLVNIEGTILFFDPVFSESAA
PFSFMVKRFQDAVVKLEEIPKVDYIIISHDHYDHLDMETIEFFKSKQTRFITPLGVTSHIKEWGVSEDRLTELDWWEKLD
LGKIQIVCTPAQHFSGRRGMNGNKTLWSSWTILGQKERFYFSGDSGYDIHFKQIGETYGPFDLTFIENGQYNPMWEAVHV
LPEQTAKAHLDLKGKALVPVHWGMFNLSLHSWYEPAENIEREAKKHNINLLTPKFGQLVKLKNPNLLERWWKKYIEQN
>Mature_398_residues
MDIELSGIDFPSANCLKKDHMSGKNTLPSALVSICFGFILTLTFVHCKAFGKDPEGAHKEKIQKSSHFDPTREQFVNRRP
DILEKMREGQNFFSLFVKFMFGGDKNQKPSAKLPEEKPNFKEFLEPDESIKFIWFGHSTFLVNIEGTILFFDPVFSESAA
PFSFMVKRFQDAVVKLEEIPKVDYIIISHDHYDHLDMETIEFFKSKQTRFITPLGVTSHIKEWGVSEDRLTELDWWEKLD
LGKIQIVCTPAQHFSGRRGMNGNKTLWSSWTILGQKERFYFSGDSGYDIHFKQIGETYGPFDLTFIENGQYNPMWEAVHV
LPEQTAKAHLDLKGKALVPVHWGMFNLSLHSWYEPAENIEREAKKHNINLLTPKFGQLVKLKNPNLLERWWKKYIEQN

Specific function: Unknown

COG id: COG2220

COG function: function code R; Predicted Zn-dependent hydrolases of the beta-lactamase fold

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To K.pneumoniae romA [H]

Homologues:

Organism=Homo sapiens, GI170932483, Length=287, Percent_Identity=35.191637630662, Blast_Score=187, Evalue=1e-47,
Organism=Homo sapiens, GI170932481, Length=287, Percent_Identity=35.191637630662, Blast_Score=187, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI17543104, Length=242, Percent_Identity=38.0165289256198, Blast_Score=174, Evalue=9e-44,
Organism=Caenorhabditis elegans, GI17543102, Length=265, Percent_Identity=35.4716981132075, Blast_Score=167, Evalue=6e-42,
Organism=Caenorhabditis elegans, GI17543100, Length=265, Percent_Identity=35.4716981132075, Blast_Score=167, Evalue=7e-42,
Organism=Caenorhabditis elegans, GI25148824, Length=265, Percent_Identity=35.4716981132075, Blast_Score=167, Evalue=8e-42,
Organism=Saccharomyces cerevisiae, GI6325154, Length=242, Percent_Identity=34.7107438016529, Blast_Score=134, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 46279; Mature: 46279

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIELSGIDFPSANCLKKDHMSGKNTLPSALVSICFGFILTLTFVHCKAFGKDPEGAHKE
CCEEECCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
KIQKSSHFDPTREQFVNRRPDILEKMREGQNFFSLFVKFMFGGDKNQKPSAKLPEEKPNF
HHHHHCCCCHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCH
KEFLEPDESIKFIWFGHSTFLVNIEGTILFFDPVFSESAAPFSFMVKRFQDAVVKLEEIP
HHHCCCCCCEEEEEEECEEEEEEECEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCC
KVDYIIISHDHYDHLDMETIEFFKSKQTRFITPLGVTSHIKEWGVSEDRLTELDWWEKLD
CEEEEEEECCCCCCCCHHHHHHHHCCCCEEEECCCHHHHHHHHCCCHHHCCCCHHHHCCC
LGKIQIVCTPAQHFSGRRGMNGNKTLWSSWTILGQKERFYFSGDSGYDIHFKQIGETYGP
CCEEEEEEECHHHCCCCCCCCCCCEEEEEEEEEECCCEEEECCCCCCEEEHHHHCCCCCC
FDLTFIENGQYNPMWEAVHVLPEQTAKAHLDLKGKALVPVHWGMFNLSLHSWYEPAENIE
EEEEEEECCCCCHHHHHHHHHHHHHHHEEECCCCCEEEEEECCEEEEEHHHHCCCHHHHH
REAKKHNINLLTPKFGQLVKLKNPNLLERWWKKYIEQN
HHHHHCCCEEECCCCCCEEEECCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MDIELSGIDFPSANCLKKDHMSGKNTLPSALVSICFGFILTLTFVHCKAFGKDPEGAHKE
CCEEECCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
KIQKSSHFDPTREQFVNRRPDILEKMREGQNFFSLFVKFMFGGDKNQKPSAKLPEEKPNF
HHHHHCCCCHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCH
KEFLEPDESIKFIWFGHSTFLVNIEGTILFFDPVFSESAAPFSFMVKRFQDAVVKLEEIP
HHHCCCCCCEEEEEEECEEEEEEECEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCC
KVDYIIISHDHYDHLDMETIEFFKSKQTRFITPLGVTSHIKEWGVSEDRLTELDWWEKLD
CEEEEEEECCCCCCCCHHHHHHHHCCCCEEEECCCHHHHHHHHCCCHHHCCCCHHHHCCC
LGKIQIVCTPAQHFSGRRGMNGNKTLWSSWTILGQKERFYFSGDSGYDIHFKQIGETYGP
CCEEEEEEECHHHCCCCCCCCCCCEEEEEEEEEECCCEEEECCCCCCEEEHHHHCCCCCC
FDLTFIENGQYNPMWEAVHVLPEQTAKAHLDLKGKALVPVHWGMFNLSLHSWYEPAENIE
EEEEEEECCCCCHHHHHHHHHHHHHHHEEECCCCCEEEEEECCEEEEEHHHHCCCHHHHH
REAKKHNINLLTPKFGQLVKLKNPNLLERWWKKYIEQN
HHHHHCCCEEECCCCCCEEEECCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]