| Definition | Leptospira biflexa serovar Patoc strain 'Patoc 1 (Paris)' chromosome chromosome I, complete sequence. |
|---|---|
| Accession | NC_010602 |
| Length | 3,599,677 |
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The map label for this gene is aphA [H]
Identifier: 183220479
GI number: 183220479
Start: 1123405
End: 1126014
Strand: Direct
Name: aphA [H]
Synonym: LEPBI_I1078
Alternate gene names: 183220479
Gene position: 1123405-1126014 (Clockwise)
Preceding gene: 183220478
Following gene: 183220480
Centisome position: 31.21
GC content: 32.34
Gene sequence:
>2610_bases ATGGATCAACTTGATGATATTTCAGTATCCGACGCCATCTTCAATACCTTTCCAGGGATCGCATTTTTACTTTCAACGGA AGGAGCCCTTTTACGTCGGAATCAGAATTTTGAAGATTTTCTTACAATCAATACAAAAGTAAATCAAAACAAAGAAAATT TTTTATCTTACGAGATACAAAGTTTTCCTTCTATCGACAAAGTGATAGAGGAGACGTGCGAAAAGGGATCGATCAATATC GAAATTGAATTCATTAAAAGCGAAAATCAATCAATTCCATTTTTACTCACTTGTAAAACGATTCTCTATCAAAAACAAAG ATGTATTTTAGGTTATGCTCTCCATCTTTCCGGAAAGAATCAATTGAGAGAAGAGCTGACTCGTAAAGACGATTTCCTCA ATGAGCGTATTAAAGAATTAAACACTCTTCATGCGACAAATGCGATATTGCATTCTAATCATCGTTCTATCGATGAAATT CTATCGGAGTTTGTGAAACTATTACCATCAGGATGGCAATATCCAGAGATAACAGCTGCTCGTATCAATTTTAATCACAA ATTTTACGAAACAAAAAATTTCCAGAGAACAAAATGGGCTTTAAACTCTGAAATAGAGTTAATAGAGCATAACCTACTAA AAGTGGAAGTAGCCTATCTTGAAGAAAAACCAGTTAGGGATGTGGGGCCTTTTTTAAAGGAAGAGATAGAACTAATTAAC TCGTTGGCGAATATGATAGCATCGTTTTTGGAAAAGGCCATCGAGTCTGAAAAAATAAGAGAATTGGAAGCAAATCTCAA TTCTATCTTTCAAAGCACTGACACTAGTTATATTTTAATAGATAAAGATTATCGAATTGTAATGTTTAATCAGATTGCCT ACGATCGAACCAATTTTGTTTTTAACAAACAATTGAAAGTAGGTCGTTCATTCTTTGAAATCGTAGCGGAAGAAAGGCAG GAAATTACGAGATTAAACTTTGAAAAAGTAATGGCAGGTGAAGTTGTAAAATATGAAATATCCTATTTGATCAATAATGT TCCATTTTATTTTTTAACAATGTTTACGCCGATTAAATCGGAGAATGATGAAGTGAATGGTATTTGTTTTACCTCCCTTG ATTTTACTCTACATAAAAATTTCGAGAATCAAAAGGAATTGTTTGTCTCGATTGTGAATTCATCGCAAGATGCAATCTTT TCAAACGACTTAAATGGTATCATTACAAGCTGGAATAAAAGTGCTGAAAAAATTTTCGGATACTCTGAAAACGAAGCAAT TGGAAAACATAATTCGATGCTTTATCCTGAGGGTCAGGCGAAAAAGGGAAAATTTGATTTTATACATTCAGAAAAGTATC AAGTCTTAGAAAATTATGAAACCAAAATGTTGGCAAAAGGTAACAGATTATTTGATGTTTCTCTTTCCGAATCCCCGATT AAAAATTTCCAAGGTGTAATTTCTGGAACTTCAAACATTGTTCGAGATATCACACAAAAAAAACAAATTGAGGTGGCACT GCTTAAATCCGAAGCAAACTTACAAACAATTCTAAGTGTTACGAAAATTGCTTATATTTTGTTTGATGTCAATTTAAAGA TTATCTCCTTTAATAACAAATCCGTCGAATTCGTAAAAAAAGAGTTAGGTCATACATTATGTAACGGCGATTTTTTTCAT GATTATTTAAGTGATAAGCATAATGGAATTTTTGATCATCTTTTGAGAGCATTAGGAGGCGAAGAGTTCGGTTTTGAAGT TCAGTACAAACAATATGATAGGAGTGTAAGTTGGTATTATTTCACGATCAATCCCATCAAAAATAATATGAATCAATCGA TTGGGGTTTTGCTATCTATCGAAAATATTTCAGAATTCAAAAAGGAAGAGATGCAACGTTTAAAGCTGACAAATGATTTC ATTCAAAGAAATAAGGACCTCGAACAGTTTGCTTATATTGTATCTCATAATTTACGTGCGCCTGTTGCGAATATCATCGG TTTAGCAAGAGAGCTAAACGAAGATTCGTTAGAAGAAGAAAATCGTAAATTATTTGGGAAAGAATTGTCGGTAACTGTTT CAAAGTTAGATGACGTGATTCGGGATTTAAATTTTATATTGCAAGTCAAACGTGAAGTTTTTGAAAATAAAGAAACTATT TTCTTCCAAAAACTATTATTTGAAATTTGGAATAGTCTCGAGACTTTAGCTGAGAAAGAAAATGTAACACTTCAAACTGA TTTTTCCGAATTAGAAAAGATTGAATCAACAAAAACATATCTTTATAGTATATTTTATAATTTGTTAACAAATAGTATAA AATATAGGCGCCCAGGTCAGCCTACTTTGATACAAGTGTCCAGTAAAAAGAAACAAGATTCCCTTTTACTGGTATTTAAA GATAACGGAATGGGAATCGATTTGGAAAAGAAAGGCGACCAACTGTTTGGGATGTACAAAAGGTTTCATTTGAATACATC CATAGGAAAAGGAATGGGTTTATTTATTACTAAGACTCAGGTGGAAGCCATCGGTGGAAATATTTCTGTTAAAAGTAATG TTAATATTGGAACCGAGTTTGTAATTGAATTGCCTTTATTGAATGAATGA
Upstream 100 bases:
>100_bases ATGAAATGTTGCCTCACTCATTTATAGTAGGATAGGCATTCTCGTGATCGATTTATTACCAAATTCGAATCTTTTGATTT TGCCTAAAAGTTAATTGTAG
Downstream 100 bases:
>100_bases ATACAATTGCGATATTAATCGAACCATATTTTTTACAAAATCAAATTCAGGGCGCACTAGAATAACATGAATTTTCCCAA TCGTTTTTTGTTAGTTGATG
Product: putative two-component hybrid sensor and regulator
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 869; Mature: 869
Protein sequence:
>869_residues MDQLDDISVSDAIFNTFPGIAFLLSTEGALLRRNQNFEDFLTINTKVNQNKENFLSYEIQSFPSIDKVIEETCEKGSINI EIEFIKSENQSIPFLLTCKTILYQKQRCILGYALHLSGKNQLREELTRKDDFLNERIKELNTLHATNAILHSNHRSIDEI LSEFVKLLPSGWQYPEITAARINFNHKFYETKNFQRTKWALNSEIELIEHNLLKVEVAYLEEKPVRDVGPFLKEEIELIN SLANMIASFLEKAIESEKIRELEANLNSIFQSTDTSYILIDKDYRIVMFNQIAYDRTNFVFNKQLKVGRSFFEIVAEERQ EITRLNFEKVMAGEVVKYEISYLINNVPFYFLTMFTPIKSENDEVNGICFTSLDFTLHKNFENQKELFVSIVNSSQDAIF SNDLNGIITSWNKSAEKIFGYSENEAIGKHNSMLYPEGQAKKGKFDFIHSEKYQVLENYETKMLAKGNRLFDVSLSESPI KNFQGVISGTSNIVRDITQKKQIEVALLKSEANLQTILSVTKIAYILFDVNLKIISFNNKSVEFVKKELGHTLCNGDFFH DYLSDKHNGIFDHLLRALGGEEFGFEVQYKQYDRSVSWYYFTINPIKNNMNQSIGVLLSIENISEFKKEEMQRLKLTNDF IQRNKDLEQFAYIVSHNLRAPVANIIGLARELNEDSLEEENRKLFGKELSVTVSKLDDVIRDLNFILQVKREVFENKETI FFQKLLFEIWNSLETLAEKENVTLQTDFSELEKIESTKTYLYSIFYNLLTNSIKYRRPGQPTLIQVSSKKKQDSLLLVFK DNGMGIDLEKKGDQLFGMYKRFHLNTSIGKGMGLFITKTQVEAIGGNISVKSNVNIGTEFVIELPLLNE
Sequences:
>Translated_869_residues MDQLDDISVSDAIFNTFPGIAFLLSTEGALLRRNQNFEDFLTINTKVNQNKENFLSYEIQSFPSIDKVIEETCEKGSINI EIEFIKSENQSIPFLLTCKTILYQKQRCILGYALHLSGKNQLREELTRKDDFLNERIKELNTLHATNAILHSNHRSIDEI LSEFVKLLPSGWQYPEITAARINFNHKFYETKNFQRTKWALNSEIELIEHNLLKVEVAYLEEKPVRDVGPFLKEEIELIN SLANMIASFLEKAIESEKIRELEANLNSIFQSTDTSYILIDKDYRIVMFNQIAYDRTNFVFNKQLKVGRSFFEIVAEERQ EITRLNFEKVMAGEVVKYEISYLINNVPFYFLTMFTPIKSENDEVNGICFTSLDFTLHKNFENQKELFVSIVNSSQDAIF SNDLNGIITSWNKSAEKIFGYSENEAIGKHNSMLYPEGQAKKGKFDFIHSEKYQVLENYETKMLAKGNRLFDVSLSESPI KNFQGVISGTSNIVRDITQKKQIEVALLKSEANLQTILSVTKIAYILFDVNLKIISFNNKSVEFVKKELGHTLCNGDFFH DYLSDKHNGIFDHLLRALGGEEFGFEVQYKQYDRSVSWYYFTINPIKNNMNQSIGVLLSIENISEFKKEEMQRLKLTNDF IQRNKDLEQFAYIVSHNLRAPVANIIGLARELNEDSLEEENRKLFGKELSVTVSKLDDVIRDLNFILQVKREVFENKETI FFQKLLFEIWNSLETLAEKENVTLQTDFSELEKIESTKTYLYSIFYNLLTNSIKYRRPGQPTLIQVSSKKKQDSLLLVFK DNGMGIDLEKKGDQLFGMYKRFHLNTSIGKGMGLFITKTQVEAIGGNISVKSNVNIGTEFVIELPLLNE >Mature_869_residues MDQLDDISVSDAIFNTFPGIAFLLSTEGALLRRNQNFEDFLTINTKVNQNKENFLSYEIQSFPSIDKVIEETCEKGSINI EIEFIKSENQSIPFLLTCKTILYQKQRCILGYALHLSGKNQLREELTRKDDFLNERIKELNTLHATNAILHSNHRSIDEI LSEFVKLLPSGWQYPEITAARINFNHKFYETKNFQRTKWALNSEIELIEHNLLKVEVAYLEEKPVRDVGPFLKEEIELIN SLANMIASFLEKAIESEKIRELEANLNSIFQSTDTSYILIDKDYRIVMFNQIAYDRTNFVFNKQLKVGRSFFEIVAEERQ EITRLNFEKVMAGEVVKYEISYLINNVPFYFLTMFTPIKSENDEVNGICFTSLDFTLHKNFENQKELFVSIVNSSQDAIF SNDLNGIITSWNKSAEKIFGYSENEAIGKHNSMLYPEGQAKKGKFDFIHSEKYQVLENYETKMLAKGNRLFDVSLSESPI KNFQGVISGTSNIVRDITQKKQIEVALLKSEANLQTILSVTKIAYILFDVNLKIISFNNKSVEFVKKELGHTLCNGDFFH DYLSDKHNGIFDHLLRALGGEEFGFEVQYKQYDRSVSWYYFTINPIKNNMNQSIGVLLSIENISEFKKEEMQRLKLTNDF IQRNKDLEQFAYIVSHNLRAPVANIIGLARELNEDSLEEENRKLFGKELSVTVSKLDDVIRDLNFILQVKREVFENKETI FFQKLLFEIWNSLETLAEKENVTLQTDFSELEKIESTKTYLYSIFYNLLTNSIKYRRPGQPTLIQVSSKKKQDSLLLVFK DNGMGIDLEKKGDQLFGMYKRFHLNTSIGKGMGLFITKTQVEAIGGNISVKSNVNIGTEFVIELPLLNE
Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Integral Membrane Protein. Inner Membrane [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 histidine kinase domain [H]
Homologues:
Organism=Escherichia coli, GI48994928, Length=244, Percent_Identity=25.4098360655738, Blast_Score=73, Evalue=7e-14, Organism=Escherichia coli, GI1788549, Length=327, Percent_Identity=23.2415902140673, Blast_Score=65, Evalue=2e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003594 - InterPro: IPR003018 - InterPro: IPR013654 - InterPro: IPR016132 - InterPro: IPR001294 - InterPro: IPR013515 - InterPro: IPR003661 - InterPro: IPR005467 - InterPro: IPR009082 [H]
Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]
EC number: =2.7.13.3 [H]
Molecular weight: Translated: 100560; Mature: 100560
Theoretical pI: Translated: 5.34; Mature: 5.34
Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.6 %Cys (Translated Protein) 1.4 %Met (Translated Protein) 2.0 %Cys+Met (Translated Protein) 0.6 %Cys (Mature Protein) 1.4 %Met (Mature Protein) 2.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MDQLDDISVSDAIFNTFPGIAFLLSTEGALLRRNQNFEDFLTINTKVNQNKENFLSYEIQ CCCCCCCCHHHHHHHHCCCEEEEEECCCHHEECCCCCCCEEEEEEEECCCHHHHHHHHHH SFPSIDKVIEETCEKGSINIEIEFIKSENQSIPFLLTCKTILYQKQRCILGYALHLSGKN CCCCHHHHHHHHHCCCCEEEEEEEEECCCCCCCEEEEHHHHHHHHHHEEEEEEEEECCHH QLREELTRKDDFLNERIKELNTLHATNAILHSNHRSIDEILSEFVKLLPSGWQYPEITAA HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCEEEE RINFNHKFYETKNFQRTKWALNSEIELIEHNLLKVEVAYLEEKPVRDVGPFLKEEIELIN EEECCEEEEECCCCCHHHHHCCCCHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHH SLANMIASFLEKAIESEKIRELEANLNSIFQSTDTSYILIDKDYRIVMFNQIAYDRTNFV HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCEEEEEECHHHCCCCCE FNKQLKVGRSFFEIVAEERQEITRLNFEKVMAGEVVKYEISYLINNVPFYFLTMFTPIKS EECHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCHHHHHHHHHHHHCCCCEEHEEECCCCC ENDEVNGICFTSLDFTLHKNFENQKELFVSIVNSSQDAIFSNDLNGIITSWNKSAEKIFG CCCCCCEEEEEEEEEEEECCCCHHHHHHHHHHCCCCCCEECCCCCCCEECCCCCHHHHCC YSENEAIGKHNSMLYPEGQAKKGKFDFIHSEKYQVLENYETKMLAKGNRLFDVSLSESPI CCCCCCCCCCCCEECCCCCCCCCCEEEEECHHHHHHHHHHHHHHCCCCEEEEECCCCCHH KNFQGVISGTSNIVRDITQKKQIEVALLKSEANLQTILSVTKIAYILFDVNLKIISFNNK HHHHHHHCCHHHHHHHHHHHHHEEEEEEECCCCHHHHHHHHHHHHHEEEEEEEEEEECCC SVEFVKKELGHTLCNGDFFHDYLSDKHNGIFDHLLRALGGEEFGFEVQYKQYDRSVSWYY HHHHHHHHHCHHHCCCCHHHHHHCCCCCCHHHHHHHHHCCCCCCEEEEEHHHCCCEEEEE FTINPIKNNMNQSIGVLLSIENISEFKKEEMQRLKLTNDFIQRNKDLEQFAYIVSHNLRA EEEECHHCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCC PVANIIGLARELNEDSLEEENRKLFGKELSVTVSKLDDVIRDLNFILQVKREVFENKETI CHHHHHHHHHHCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH FFQKLLFEIWNSLETLAEKENVTLQTDFSELEKIESTKTYLYSIFYNLLTNSIKYRRPGQ HHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC PTLIQVSSKKKQDSLLLVFKDNGMGIDLEKKGDQLFGMYKRFHLNTSIGKGMGLFITKTQ CCEEEECCCCCCCCEEEEEECCCCEEEECCCCCHHHHHHHHHEECCCCCCCCEEEEEEEE VEAIGGNISVKSNVNIGTEFVIELPLLNE HHHCCCCEEEECCCCCCCEEEEECCCCCC >Mature Secondary Structure MDQLDDISVSDAIFNTFPGIAFLLSTEGALLRRNQNFEDFLTINTKVNQNKENFLSYEIQ CCCCCCCCHHHHHHHHCCCEEEEEECCCHHEECCCCCCCEEEEEEEECCCHHHHHHHHHH SFPSIDKVIEETCEKGSINIEIEFIKSENQSIPFLLTCKTILYQKQRCILGYALHLSGKN CCCCHHHHHHHHHCCCCEEEEEEEEECCCCCCCEEEEHHHHHHHHHHEEEEEEEEECCHH QLREELTRKDDFLNERIKELNTLHATNAILHSNHRSIDEILSEFVKLLPSGWQYPEITAA HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCEEEE RINFNHKFYETKNFQRTKWALNSEIELIEHNLLKVEVAYLEEKPVRDVGPFLKEEIELIN EEECCEEEEECCCCCHHHHHCCCCHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHH SLANMIASFLEKAIESEKIRELEANLNSIFQSTDTSYILIDKDYRIVMFNQIAYDRTNFV HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCEEEEEECHHHCCCCCE FNKQLKVGRSFFEIVAEERQEITRLNFEKVMAGEVVKYEISYLINNVPFYFLTMFTPIKS EECHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCHHHHHHHHHHHHCCCCEEHEEECCCCC ENDEVNGICFTSLDFTLHKNFENQKELFVSIVNSSQDAIFSNDLNGIITSWNKSAEKIFG CCCCCCEEEEEEEEEEEECCCCHHHHHHHHHHCCCCCCEECCCCCCCEECCCCCHHHHCC YSENEAIGKHNSMLYPEGQAKKGKFDFIHSEKYQVLENYETKMLAKGNRLFDVSLSESPI CCCCCCCCCCCCEECCCCCCCCCCEEEEECHHHHHHHHHHHHHHCCCCEEEEECCCCCHH KNFQGVISGTSNIVRDITQKKQIEVALLKSEANLQTILSVTKIAYILFDVNLKIISFNNK HHHHHHHCCHHHHHHHHHHHHHEEEEEEECCCCHHHHHHHHHHHHHEEEEEEEEEEECCC SVEFVKKELGHTLCNGDFFHDYLSDKHNGIFDHLLRALGGEEFGFEVQYKQYDRSVSWYY HHHHHHHHHCHHHCCCCHHHHHHCCCCCCHHHHHHHHHCCCCCCEEEEEHHHCCCEEEEE FTINPIKNNMNQSIGVLLSIENISEFKKEEMQRLKLTNDFIQRNKDLEQFAYIVSHNLRA EEEECHHCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCC PVANIIGLARELNEDSLEEENRKLFGKELSVTVSKLDDVIRDLNFILQVKREVFENKETI CHHHHHHHHHHCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH FFQKLLFEIWNSLETLAEKENVTLQTDFSELEKIESTKTYLYSIFYNLLTNSIKYRRPGQ HHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC PTLIQVSSKKKQDSLLLVFKDNGMGIDLEKKGDQLFGMYKRFHLNTSIGKGMGLFITKTQ CCEEEECCCCCCCCEEEEEECCCCEEEECCCCCHHHHHHHHHEECCCCCCCCEEEEEEEE VEAIGGNISVKSNVNIGTEFVIELPLLNE HHHCCCCEEEECCCCCCCEEEEECCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 11759840 [H]