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The map label for this gene is tlpC [H]

Identifier: 183220478

GI number: 183220478

Start: 1118639

End: 1120420

Strand: Direct

Name: tlpC [H]

Synonym: LEPBI_I1075

Alternate gene names: 183220478

Gene position: 1118639-1120420 (Clockwise)

Preceding gene: 183220477

Following gene: 183220479

Centisome position: 31.08

GC content: 36.03

Gene sequence:

>1782_bases
ATGACAGAGAATCGATTGATCCGGAAATTAACAGTTGCCATTGAAGCTCCATTATACCTTTTAATCTTTCCTTATTTTAT
AAATTTCTGTTTATTTGCCTCTGGTTTTGACACAGATACTCTGATCCAACTTGCTGTAATCGGAACATTACTCTCGCTTG
TACCTTTAGTGCTAGGGATTACCTTACGCAATCGAAGGTTAAAACGTTTACTAAGTTATTCCAAATCATCAAATATTGAA
GAAATCTCCAATTTAAAAAAGGGATTATTGGAACACCCTCGCTGGGAAGGTAACGTTATTTTAATCCGATGGTCAGTTTC
AATATTAGGTTTTTCGTTTATGGCAGTCACAGTTTTGGGTTTACCTTGGGGAGAAATCATTGCCTTACCTTATGCCTGCG
TGATGTTAGTTCCTATAATCTATTTGGCATTTTATTTTCAATCAGAAGTATATTTAAGTGCAGTTTTACGAGATAAAACT
TTAGCAAATGTATCCTTAGATGAAAACAAGGTTCGTGTTTTTGGAGTTTTCCAAAGAAACCTGTATACGGTTTTGGCAGT
GGCAATACTCCCTATGTTAACTTTTGGTTATTATTTATTTTTAATATTAGCCACAAATTTCAGATCTCCTTACTGGTTTT
ATCAATTGCCTATTGTATTCGTAATGATGCTTGTGATTATGGTCTATGCTGCTTATGTAGGTAGTAAATCACTAAAGGAA
GATATTGGTAACCTCAACCATTCGATTGAAACCTTATCAAAAGGAGAACTTTCAGAATCGATTCCACAACTTTCAGCAAC
AAATCTTAGTCATACGATTGTGAAACTCAATTTGTTCATGGATTCATTGCGGGTTTATTTTCAGACTGCCAAAAAAGAAG
CAGTCACACTTTCTGATACTTCAAGAACGATTTTAAATAAAGGTATCGAAGTAGATTCACAAGTTGTCTCTGAAAAAAAT
AAAATTGATTCAACCTTTGCTTCTGTCCATCAAATCCAAAGTCTCTCGAAATCCACATACGAACGTGTTCATTCTCAAAA
GGTCAAAACCAATTTTTTGGCCAATGAATTAACTCGCGTCACTCAAGAAATGGCGAATCTTTCTAAAAAAGCAGAAGAAT
TGGTGATCAATACAAATCACTCAATTGGCACTGTAAAAGTATCAGGTGATGCCATTCAATCCGCGTATGAAAAAGTAGAA
CAGATGAACCAAATGAGTGAAAATATCAAATCGGCAATTTCCATTGTAGAAGATATTTCTGATCGAGTGAATTTGCTTTC
ATTAAATGCATCCATTGAAGCGGCACGAGCTGGTTCGATGGGGCGCGGATTTGCCGTCGTTGCGAGTGAAGTATCTCGTC
TTGCAGACGAAACAGCAAAGAATATCGAAGAAATCAAACGTGTTGTAAAATTATCACAGGTAACATCTAAAGAAAGTCTG
GAATCCATGAAGGAAATTATCTCAACCAATAATGATGTAAAATCTAAATTTGAAGAGATATCCCTAGTCGCTCAACTTTT
TGGGAAAACAAGTGAAACGAGTTCGGAAAACGTAAAATCACTCAAAGATCTAGTAGGTGAATTCCAGTTGGACGCGGAAA
AAATCACAAGTGAGATGGAGTTACAAACCATCTACACGGAAACATCCAATTCCAACTTGCAGGAATTATGGGAAAATCAC
TCTCAAATCTCGACAACCTTTGGTGAAATTTCAGAGGAAGCAAATCGTTTGCAACTGGTATCTGACTCGATGGAAAAAAT
TGTTTCTCGGTTCCGATTTTAA

Upstream 100 bases:

>100_bases
AAATAGGATCGTTTGTTCTATCGAGAAAAATTATGAAAAATGGTGATGTCACTTTGCTTTCCTGAAATATTTGACAAACA
GATAGGAAGGTTTGTAGGAA

Downstream 100 bases:

>100_bases
AATAACGTTTACGAGAGAAAATAAAAGTCGACTCATTCTTTTCCAATTCACTTTCCATACACTCGTTCGGGCGATCTTGT
TCTTTTGTTTCTTTTACAAA

Product: putative methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 593; Mature: 592

Protein sequence:

>593_residues
MTENRLIRKLTVAIEAPLYLLIFPYFINFCLFASGFDTDTLIQLAVIGTLLSLVPLVLGITLRNRRLKRLLSYSKSSNIE
EISNLKKGLLEHPRWEGNVILIRWSVSILGFSFMAVTVLGLPWGEIIALPYACVMLVPIIYLAFYFQSEVYLSAVLRDKT
LANVSLDENKVRVFGVFQRNLYTVLAVAILPMLTFGYYLFLILATNFRSPYWFYQLPIVFVMMLVIMVYAAYVGSKSLKE
DIGNLNHSIETLSKGELSESIPQLSATNLSHTIVKLNLFMDSLRVYFQTAKKEAVTLSDTSRTILNKGIEVDSQVVSEKN
KIDSTFASVHQIQSLSKSTYERVHSQKVKTNFLANELTRVTQEMANLSKKAEELVINTNHSIGTVKVSGDAIQSAYEKVE
QMNQMSENIKSAISIVEDISDRVNLLSLNASIEAARAGSMGRGFAVVASEVSRLADETAKNIEEIKRVVKLSQVTSKESL
ESMKEIISTNNDVKSKFEEISLVAQLFGKTSETSSENVKSLKDLVGEFQLDAEKITSEMELQTIYTETSNSNLQELWENH
SQISTTFGEISEEANRLQLVSDSMEKIVSRFRF

Sequences:

>Translated_593_residues
MTENRLIRKLTVAIEAPLYLLIFPYFINFCLFASGFDTDTLIQLAVIGTLLSLVPLVLGITLRNRRLKRLLSYSKSSNIE
EISNLKKGLLEHPRWEGNVILIRWSVSILGFSFMAVTVLGLPWGEIIALPYACVMLVPIIYLAFYFQSEVYLSAVLRDKT
LANVSLDENKVRVFGVFQRNLYTVLAVAILPMLTFGYYLFLILATNFRSPYWFYQLPIVFVMMLVIMVYAAYVGSKSLKE
DIGNLNHSIETLSKGELSESIPQLSATNLSHTIVKLNLFMDSLRVYFQTAKKEAVTLSDTSRTILNKGIEVDSQVVSEKN
KIDSTFASVHQIQSLSKSTYERVHSQKVKTNFLANELTRVTQEMANLSKKAEELVINTNHSIGTVKVSGDAIQSAYEKVE
QMNQMSENIKSAISIVEDISDRVNLLSLNASIEAARAGSMGRGFAVVASEVSRLADETAKNIEEIKRVVKLSQVTSKESL
ESMKEIISTNNDVKSKFEEISLVAQLFGKTSETSSENVKSLKDLVGEFQLDAEKITSEMELQTIYTETSNSNLQELWENH
SQISTTFGEISEEANRLQLVSDSMEKIVSRFRF
>Mature_592_residues
TENRLIRKLTVAIEAPLYLLIFPYFINFCLFASGFDTDTLIQLAVIGTLLSLVPLVLGITLRNRRLKRLLSYSKSSNIEE
ISNLKKGLLEHPRWEGNVILIRWSVSILGFSFMAVTVLGLPWGEIIALPYACVMLVPIIYLAFYFQSEVYLSAVLRDKTL
ANVSLDENKVRVFGVFQRNLYTVLAVAILPMLTFGYYLFLILATNFRSPYWFYQLPIVFVMMLVIMVYAAYVGSKSLKED
IGNLNHSIETLSKGELSESIPQLSATNLSHTIVKLNLFMDSLRVYFQTAKKEAVTLSDTSRTILNKGIEVDSQVVSEKNK
IDSTFASVHQIQSLSKSTYERVHSQKVKTNFLANELTRVTQEMANLSKKAEELVINTNHSIGTVKVSGDAIQSAYEKVEQ
MNQMSENIKSAISIVEDISDRVNLLSLNASIEAARAGSMGRGFAVVASEVSRLADETAKNIEEIKRVVKLSQVTSKESLE
SMKEIISTNNDVKSKFEEISLVAQLFGKTSETSSENVKSLKDLVGEFQLDAEKITSEMELQTIYTETSNSNLQELWENHS
QISTTFGEISEEANRLQLVSDSMEKIVSRFRF

Specific function: Signal Transducer For Aerotaxis. The Aerotactic Response Is The Accumulation Of Cells Around Air Bubbles. The Nature Of The Sensory Stimulus Detected By This Protein Is The Proton Motive Force Or Cellular Redox State. It Uses A FAD Prosthetic Group As A R

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=338, Percent_Identity=24.2603550295858, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI2367378, Length=230, Percent_Identity=25.6521739130435, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1788194, Length=117, Percent_Identity=35.8974358974359, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1788195, Length=205, Percent_Identity=28.2926829268293, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1787690, Length=258, Percent_Identity=24.8062015503876, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 66646; Mature: 66515

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHEECCCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TENRLIRKLTVAIEAPLYLLIFPYFINFCLFASGFDTDTLIQLAVIGTLLSLVPLVLGI
CCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
TLRNRRLKRLLSYSKSSNIEEISNLKKGLLEHPRWEGNVILIRWSVSILGFSFMAVTVLG
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEHHHHHHHHHHHHHHHC
LPWGEIIALPYACVMLVPIIYLAFYFQSEVYLSAVLRDKTLANVSLDENKVRVFGVFQRN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHH
LYTVLAVAILPMLTFGYYLFLILATNFRSPYWFYQLPIVFVMMLVIMVYAAYVGSKSLKE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
DIGNLNHSIETLSKGELSESIPQLSATNLSHTIVKLNLFMDSLRVYFQTAKKEAVTLSDT
HHHHHHHHHHHHHHCCHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCEEEECCH
SRTILNKGIEVDSQVVSEKNKIDSTFASVHQIQSLSKSTYERVHSQKVKTNFLANELTRV
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TQEMANLSKKAEELVINTNHSIGTVKVSGDAIQSAYEKVEQMNQMSENIKSAISIVEDIS
HHHHHHHHHHHHHHEEECCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DRVNLLSLNASIEAARAGSMGRGFAVVASEVSRLADETAKNIEEIKRVVKLSQVTSKESL
HHHHEEEECCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ESMKEIISTNNDVKSKFEEISLVAQLFGKTSETSSENVKSLKDLVGEFQLDAEKITSEME
HHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHH
LQTIYTETSNSNLQELWENHSQISTTFGEISEEANRLQLVSDSMEKIVSRFRF
HHHHEECCCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7921238; 7704255; 8969502; 9384377 [H]