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The map label for this gene is yfbQ [C]

Identifier: 183220316

GI number: 183220316

Start: 942580

End: 943881

Strand: Direct

Name: yfbQ [C]

Synonym: LEPBI_I0912

Alternate gene names: 183220316

Gene position: 942580-943881 (Clockwise)

Preceding gene: 183220315

Following gene: 183220317

Centisome position: 26.19

GC content: 37.86

Gene sequence:

>1302_bases
ATGAGAAGAAATATAGTCCATTCGGGTGCCGATGCACTCATTTACGAAATTCGCCAGATTGTGGCACTTGCCAAACAAAT
CGAAGCCATGGGTATCACCATCACCTGGGAAAACATTGGGGATCCTATCCAAAAAGGGGAAAGTATTCCCACTTGGATGA
AAGACATTGTCAGTGGACTTGTGAACCAAAATAAATCATGGGCCTACACTGCCACCCAAGGGGATGAAAACACACGAAAA
TTTTTAGCGCAAAAAGTAAACGAAAGGGGTGGAGCACAAATCACTTCTGAGGACATTTTGTTCTTTAATGGTCTTGGTGA
TGCGGTTGCTAAAATTTTTGGTTTTATGAGAAGGGAAGCAAGGATTCTTGGCCCATCGCCCGCCTATTCTACGTTATCTT
CTGCGGAAGCTGCTCATTCTGGTTACGAACACTTAACCTATGAATTGAATCCAAATAATGATTGGATGCCAGACCTTGAA
GATATTGAAAACAAAGTAAAATACAATGACTCAATTGCGGGAATATTACTCATCAATCCAGACAATCCAACAGGTGCGGT
GTATCCAAAAGAGGTCATGCGTGAGATTGTTAAAATTTGTGAAAAGTATGATATTATCCTCATCTGTGATGAAACATATG
CTCATGTCAATTATTCGGAATGGGGGAGTATCCATTTATCAGAAGTCATTGGTGATAAAGTATGTGGATTTGCGCTCCGC
TCGATTTCAAAAGAATTTCCTTGGCCTGGCGCTCGTTGTGGTTGGTTAGAAGTATTTAATCGAAAAAATGATCCAACATT
CGAGAGATACATTAAATCTTTGTTAGATGCAAAAATGTTGGAGGTATGTTCTACTACTTTACCTCAACTATCAATCCCTT
TAGTTTACTCACATCCTGAATTCTTAAATCATCTCAAATTTAGAAATTTAAAGTTTAAAAAAAGAGCCGAAAAAGCAACT
CAATTGTTATCAGGAATTCCAGGTGTCAAGGTAATCCAACCAAAGGGTGCATTTTATCTAACTGTACTTTTTGAAGATAA
TGTATTAAAACCACATATGACCTTACCAATTCAAAATGAAAAGGTAAAAAATTTTGTATCACCACTGATGGAAAAGGCCG
CATTGGATCGTAGATTTGTTCTGCATCTATTAGCCTCTGTAGGGATTTGTGTCGTACCACTTAGTTCTTTCTGTTGTAAT
CGAAATGGTTTTAGAGTCACTCTCCTGGAAGAAGATGAAACCAAATTTGAATGGATCTATCAAACGTTAGCTGATAGTAT
GAAAAAGTATTTAGCATCGTAA

Upstream 100 bases:

>100_bases
CTTGGGGGCGTCTTACGGTTGAAGATATTAAGGGATACCCAAGAGATGGAATTATCGATCCCTTTGGTCGAAGCAGCCTA
CCAAAAGGGCAAATAATTTT

Downstream 100 bases:

>100_bases
ATGAATTCTCGCGGCAGATACAAAATTGGAATTTTTGATTCAGGTTTAGGTGGTCTATCCGTTCTGCGTACTTTATGGAA
AGAAACTTCGAACATCGATT

Product: aminotransferase

Products: oxaloacetate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MRRNIVHSGADALIYEIRQIVALAKQIEAMGITITWENIGDPIQKGESIPTWMKDIVSGLVNQNKSWAYTATQGDENTRK
FLAQKVNERGGAQITSEDILFFNGLGDAVAKIFGFMRREARILGPSPAYSTLSSAEAAHSGYEHLTYELNPNNDWMPDLE
DIENKVKYNDSIAGILLINPDNPTGAVYPKEVMREIVKICEKYDIILICDETYAHVNYSEWGSIHLSEVIGDKVCGFALR
SISKEFPWPGARCGWLEVFNRKNDPTFERYIKSLLDAKMLEVCSTTLPQLSIPLVYSHPEFLNHLKFRNLKFKKRAEKAT
QLLSGIPGVKVIQPKGAFYLTVLFEDNVLKPHMTLPIQNEKVKNFVSPLMEKAALDRRFVLHLLASVGICVVPLSSFCCN
RNGFRVTLLEEDETKFEWIYQTLADSMKKYLAS

Sequences:

>Translated_433_residues
MRRNIVHSGADALIYEIRQIVALAKQIEAMGITITWENIGDPIQKGESIPTWMKDIVSGLVNQNKSWAYTATQGDENTRK
FLAQKVNERGGAQITSEDILFFNGLGDAVAKIFGFMRREARILGPSPAYSTLSSAEAAHSGYEHLTYELNPNNDWMPDLE
DIENKVKYNDSIAGILLINPDNPTGAVYPKEVMREIVKICEKYDIILICDETYAHVNYSEWGSIHLSEVIGDKVCGFALR
SISKEFPWPGARCGWLEVFNRKNDPTFERYIKSLLDAKMLEVCSTTLPQLSIPLVYSHPEFLNHLKFRNLKFKKRAEKAT
QLLSGIPGVKVIQPKGAFYLTVLFEDNVLKPHMTLPIQNEKVKNFVSPLMEKAALDRRFVLHLLASVGICVVPLSSFCCN
RNGFRVTLLEEDETKFEWIYQTLADSMKKYLAS
>Mature_433_residues
MRRNIVHSGADALIYEIRQIVALAKQIEAMGITITWENIGDPIQKGESIPTWMKDIVSGLVNQNKSWAYTATQGDENTRK
FLAQKVNERGGAQITSEDILFFNGLGDAVAKIFGFMRREARILGPSPAYSTLSSAEAAHSGYEHLTYELNPNNDWMPDLE
DIENKVKYNDSIAGILLINPDNPTGAVYPKEVMREIVKICEKYDIILICDETYAHVNYSEWGSIHLSEVIGDKVCGFALR
SISKEFPWPGARCGWLEVFNRKNDPTFERYIKSLLDAKMLEVCSTTLPQLSIPLVYSHPEFLNHLKFRNLKFKKRAEKAT
QLLSGIPGVKVIQPKGAFYLTVLFEDNVLKPHMTLPIQNEKVKNFVSPLMEKAALDRRFVLHLLASVGICVVPLSSFCCN
RNGFRVTLLEEDETKFEWIYQTLADSMKKYLAS

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4507369, Length=340, Percent_Identity=26.1764705882353, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI215599424, Length=437, Percent_Identity=22.883295194508, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI19263340, Length=437, Percent_Identity=22.883295194508, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI4885351, Length=431, Percent_Identity=22.969837587007, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI56713256, Length=378, Percent_Identity=24.0740740740741, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI56713254, Length=378, Percent_Identity=24.0740740740741, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI1788627, Length=335, Percent_Identity=27.4626865671642, Blast_Score=134, Evalue=9e-33,
Organism=Caenorhabditis elegans, GI71981209, Length=452, Percent_Identity=24.7787610619469, Blast_Score=102, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17567663, Length=313, Percent_Identity=24.6006389776358, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71981215, Length=277, Percent_Identity=23.826714801444, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6320317, Length=359, Percent_Identity=27.5766016713092, Blast_Score=95, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6323118, Length=407, Percent_Identity=28.009828009828, Blast_Score=91, Evalue=5e-19,
Organism=Drosophila melanogaster, GI18859735, Length=314, Percent_Identity=27.7070063694268, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24641770, Length=410, Percent_Identity=26.0975609756098, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24641760, Length=410, Percent_Identity=26.0975609756098, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24641768, Length=410, Percent_Identity=26.0975609756098, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24641766, Length=410, Percent_Identity=26.0975609756098, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24641764, Length=410, Percent_Identity=26.0975609756098, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI45551451, Length=410, Percent_Identity=26.0975609756098, Blast_Score=93, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.1

Molecular weight: Translated: 49022; Mature: 49022

Theoretical pI: Translated: 6.99; Mature: 6.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRNIVHSGADALIYEIRQIVALAKQIEAMGITITWENIGDPIQKGESIPTWMKDIVSGL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHCCCCCCHHHHHHHHHH
VNQNKSWAYTATQGDENTRKFLAQKVNERGGAQITSEDILFFNGLGDAVAKIFGFMRREA
HCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCEECCCCEEEECCHHHHHHHHHHHHHHHC
RILGPSPAYSTLSSAEAAHSGYEHLTYELNPNNDWMPDLEDIENKVKYNDSIAGILLINP
EECCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHCCCCEEEEEEECC
DNPTGAVYPKEVMREIVKICEKYDIILICDETYAHVNYSEWGSIHLSEVIGDKVCGFALR
CCCCCCCCHHHHHHHHHHHHHHCCEEEEECCCCCCCCHHCCCCEEHHHHHHHHHHHHHHH
SISKEFPWPGARCGWLEVFNRKNDPTFERYIKSLLDAKMLEVCSTTLPQLSIPLVYSHPE
HHHHHCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCHH
FLNHLKFRNLKFKKRAEKATQLLSGIPGVKVIQPKGAFYLTVLFEDNVLKPHMTLPIQNE
HHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEECCCCCEEEEEEEECCCCCCCEECCCCHH
KVKNFVSPLMEKAALDRRFVLHLLASVGICVVPLSSFCCNRNGFRVTLLEEDETKFEWIY
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHH
QTLADSMKKYLAS
HHHHHHHHHHHCC
>Mature Secondary Structure
MRRNIVHSGADALIYEIRQIVALAKQIEAMGITITWENIGDPIQKGESIPTWMKDIVSGL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHCCCCCCHHHHHHHHHH
VNQNKSWAYTATQGDENTRKFLAQKVNERGGAQITSEDILFFNGLGDAVAKIFGFMRREA
HCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCEECCCCEEEECCHHHHHHHHHHHHHHHC
RILGPSPAYSTLSSAEAAHSGYEHLTYELNPNNDWMPDLEDIENKVKYNDSIAGILLINP
EECCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHCCCCEEEEEEECC
DNPTGAVYPKEVMREIVKICEKYDIILICDETYAHVNYSEWGSIHLSEVIGDKVCGFALR
CCCCCCCCHHHHHHHHHHHHHHCCEEEEECCCCCCCCHHCCCCEEHHHHHHHHHHHHHHH
SISKEFPWPGARCGWLEVFNRKNDPTFERYIKSLLDAKMLEVCSTTLPQLSIPLVYSHPE
HHHHHCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCHH
FLNHLKFRNLKFKKRAEKATQLLSGIPGVKVIQPKGAFYLTVLFEDNVLKPHMTLPIQNE
HHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEECCCCCEEEEEEEECCCCCCCEECCCCHH
KVKNFVSPLMEKAALDRRFVLHLLASVGICVVPLSSFCCNRNGFRVTLLEEDETKFEWIY
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHH
QTLADSMKKYLAS
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate; 2-oxoglutarate

Specific reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]