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The map label for this gene is aroE [H]

Identifier: 183220244

GI number: 183220244

Start: 850716

End: 851606

Strand: Reverse

Name: aroE [H]

Synonym: LEPBI_I0837

Alternate gene names: 183220244

Gene position: 851606-850716 (Counterclockwise)

Preceding gene: 183220246

Following gene: 183220243

Centisome position: 23.66

GC content: 41.19

Gene sequence:

>891_bases
TTGCATTCAAAACACACTGAGATCTTTGGCATATTGGGATTTCCCTTAGGCCATACCCTATCCCCTTGGATCCATAATAC
CCTCTTCCAGCTCTCAGATTACGATGCCGTATATTTAGTATTTGAAAACGAAGGTTGGAAAGAACTCGGCCTGAAGCCCT
TACTTGATTTAGGTGTGAAGGGAGTATCCGTCACCATTCCCTTCAAAGAATGGGCATACACGCAAGCAGAGAAGGTTTGT
GAGGCTTCTAAAGCGATGTTGGCATCGAATACCCTTCTCTTACGCGAGGGCATTGAAGCTGTGAATACAGATGGATCTGG
TGCCATACAATCCATCTTACAATCAAACCCAGAACTCTTAAACCCAAAGAGATCCAAAAACATTCTTGTACTGGGGAGTG
GCGGGAGTGCCAAAGGGATTTTGTTTTCGATTGCCAAAGAATTGGAAGGCAGAAACAAAAACCAATCCATCCATCGTAAG
GTCCACCTCCTTGCAAGAAACGAGACTGCGATGAGTGAAATCGAACAATCGTTAGGAAATCCATCTTGGTTGGGACGAGT
CACAAAAGAACAAGTGATCCAAGAAAAAGAAGAGTATGATCTCATCATCCACACCACACCTATCGGAATGAAAGGTGTAG
GTGGGGAACCCATTTTAGATTCTCAATTTTTTACCAAAAAACACACGTTATTCGACATAGTCTACAACCCTTTGGAAACT
GATCTTGTCAAAATAGCGAAACAAAAAAAAGCAAACATCATCCCAGGGTATCATATGTTGCTTTTCCAGGGGATTCGACA
GTTCGAACTATTTACGAACACAAAAGTCAAACCAAAATGGATCAAAAAAGTAGAGTCCATTCTTTTACATGAATTGAAAA
AAAGAAAATAA

Upstream 100 bases:

>100_bases
GTGCGGCAAGCGGTAATGAAATCATTGGTCTTGTACCTATCTATTACCTATTTTCGGTAAGCCATTGTTTAGTCCATAAG
ATAAAAAAAAGAGGTTTTCA

Downstream 100 bases:

>100_bases
AATCTGTATGAAGGTAAACTTTTACTAAATCATGAACTTTTTAGATTTTTTAAACGAGAGGCAAAACATTGAAAAAACAA
GAAACTTCAATGTATTCCAA

Product: shikimate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MHSKHTEIFGILGFPLGHTLSPWIHNTLFQLSDYDAVYLVFENEGWKELGLKPLLDLGVKGVSVTIPFKEWAYTQAEKVC
EASKAMLASNTLLLREGIEAVNTDGSGAIQSILQSNPELLNPKRSKNILVLGSGGSAKGILFSIAKELEGRNKNQSIHRK
VHLLARNETAMSEIEQSLGNPSWLGRVTKEQVIQEKEEYDLIIHTTPIGMKGVGGEPILDSQFFTKKHTLFDIVYNPLET
DLVKIAKQKKANIIPGYHMLLFQGIRQFELFTNTKVKPKWIKKVESILLHELKKRK

Sequences:

>Translated_296_residues
MHSKHTEIFGILGFPLGHTLSPWIHNTLFQLSDYDAVYLVFENEGWKELGLKPLLDLGVKGVSVTIPFKEWAYTQAEKVC
EASKAMLASNTLLLREGIEAVNTDGSGAIQSILQSNPELLNPKRSKNILVLGSGGSAKGILFSIAKELEGRNKNQSIHRK
VHLLARNETAMSEIEQSLGNPSWLGRVTKEQVIQEKEEYDLIIHTTPIGMKGVGGEPILDSQFFTKKHTLFDIVYNPLET
DLVKIAKQKKANIIPGYHMLLFQGIRQFELFTNTKVKPKWIKKVESILLHELKKRK
>Mature_296_residues
MHSKHTEIFGILGFPLGHTLSPWIHNTLFQLSDYDAVYLVFENEGWKELGLKPLLDLGVKGVSVTIPFKEWAYTQAEKVC
EASKAMLASNTLLLREGIEAVNTDGSGAIQSILQSNPELLNPKRSKNILVLGSGGSAKGILFSIAKELEGRNKNQSIHRK
VHLLARNETAMSEIEQSLGNPSWLGRVTKEQVIQEKEEYDLIIHTTPIGMKGVGGEPILDSQFFTKKHTLFDIVYNPLET
DLVKIAKQKKANIIPGYHMLLFQGIRQFELFTNTKVKPKWIKKVESILLHELKKRK

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787983, Length=282, Percent_Identity=25.886524822695, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1789675, Length=271, Percent_Identity=26.9372693726937, Blast_Score=74, Evalue=9e-15,
Organism=Saccharomyces cerevisiae, GI6320332, Length=289, Percent_Identity=25.2595155709343, Blast_Score=70, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 33308; Mature: 33308

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHSKHTEIFGILGFPLGHTLSPWIHNTLFQLSDYDAVYLVFENEGWKELGLKPLLDLGVK
CCCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCCCEEEEEEECCCHHHHCCHHHHHCCCC
GVSVTIPFKEWAYTQAEKVCEASKAMLASNTLLLREGIEAVNTDGSGAIQSILQSNPELL
CEEEEECHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCHHHHCCCCHHHHHHHHHCCCCCC
NPKRSKNILVLGSGGSAKGILFSIAKELEGRNKNQSIHRKVHLLARNETAMSEIEQSLGN
CCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCC
PSWLGRVTKEQVIQEKEEYDLIIHTTPIGMKGVGGEPILDSQFFTKKHTLFDIVYNPLET
CHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHH
DLVKIAKQKKANIIPGYHMLLFQGIRQFELFTNTKVKPKWIKKVESILLHELKKRK
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MHSKHTEIFGILGFPLGHTLSPWIHNTLFQLSDYDAVYLVFENEGWKELGLKPLLDLGVK
CCCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCCCEEEEEEECCCHHHHCCHHHHHCCCC
GVSVTIPFKEWAYTQAEKVCEASKAMLASNTLLLREGIEAVNTDGSGAIQSILQSNPELL
CEEEEECHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCHHHHCCCCHHHHHHHHHCCCCCC
NPKRSKNILVLGSGGSAKGILFSIAKELEGRNKNQSIHRKVHLLARNETAMSEIEQSLGN
CCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCC
PSWLGRVTKEQVIQEKEEYDLIIHTTPIGMKGVGGEPILDSQFFTKKHTLFDIVYNPLET
CHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHH
DLVKIAKQKKANIIPGYHMLLFQGIRQFELFTNTKVKPKWIKKVESILLHELKKRK
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA