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The map label for this gene is lip [H]

Identifier: 183220185

GI number: 183220185

Start: 793005

End: 794117

Strand: Direct

Name: lip [H]

Synonym: LEPBI_I0775

Alternate gene names: 183220185

Gene position: 793005-794117 (Clockwise)

Preceding gene: 183220184

Following gene: 183220186

Centisome position: 22.03

GC content: 43.4

Gene sequence:

>1113_bases
ATGAACTCTAAAAAGAAACATCTTGTTTGCCTTCTCGTCCTCCTATTGGTCACAACAGGGGTTCACGCTGGCGCAAGAAA
AACAGTATATCCAGTTGTGTTCGCACATGGATTATCTGGATTCGACAACTTACTCGGATACTACTACTTTGGTAACGACT
ACGGTACCTTTGTGGGCGATCCTTGTGACGAGTTTTTGGAAACAGCGTGTAACGGTAGCATCCACTCCAGCCAAAAGGCT
TTAGCAGCAAGTGTCACTCCCTTCCAATCTTCGGAAGTGAGAGGAACACAACTTGCTGATCGAATTCAAAACTATATGAC
CTCCACTGGTGCCACTAAGGTAAATATCATTGGTCACTCCCAAGGTGGAATTGATGCAAGGAAAGCAGCCGCAGTGTTAC
GTGCTCGTTATGGAAGACAAGTCGTACATGTGATGATCTCCGTATCAAGCCCACATAGAGGTTCCCCGACTGCGAAGTAC
ATCCTTGACCTTGGTCCTGGTGTCACGTCTGTTGTGAACGCTCTTGCGAAACTTTTCGGAAACACCATTTATGGTTCCGG
AAATGATGGGATTGCAGCCGCAAAACAATTAGTTTACAATGACTATTCATCAACAGATGGAGTCACCACTGGTATGAAAG
CATTTAATAACAATTATAATGTGAGTACCAACACAGCAAACTATTGGGGTTCCATCATCACGGCTCAAGATAGCATCAAT
ACAAACCCTGCGTTATACCTTTTGAAAGAAGGGTTTTATAACATCGATGGGGACGGGTATTGTGTAGATGATTGTGACAA
TGATGGTGCCGCAGGAAAAGGTGATGGCACACGTGGTAATAACGATGATGATGGACTTGTGGGAATTAACTCCCAACAGA
TGGGATACCGTTTGCAATACAACGAGTGTTTGATTTGTTTTGATTCCATCACTGTGAATTCCACTTTAGGTTATGTGAGT
AACTTAAATGCACCCACTTCTGCGCAAATGACATCGAAATCTTCTGTGGTCAGCCAAGACCATTTGGATGTGGTGGGAGT
TCCTCCAGATACATTTGATGAAGAAGAATTTTATGCTTCGATTTTAGAGTTTATCGTCACAAAAGGCGGTTAA

Upstream 100 bases:

>100_bases
AAGTATGTCATTGAGATATAAGATGACCCAAAATTAACACAATTAACTTGACTTTTCCATCCCCTTTGCAACAAATCTAT
AGATTGTTCAGAGGTGATTT

Downstream 100 bases:

>100_bases
GAACTTCTTTGGCAGTAGGGGAAATCCTTACTGCCAATCTCAATTCTTTTTTATAACAAGTAACAAAAACAAAAATCTTT
TCGTTTCCTTTCAACTATTA

Product: putative triacylglycerol lipase

Products: NA

Alternate protein names: Triacylglycerol lipase [H]

Number of amino acids: Translated: 370; Mature: 370

Protein sequence:

>370_residues
MNSKKKHLVCLLVLLLVTTGVHAGARKTVYPVVFAHGLSGFDNLLGYYYFGNDYGTFVGDPCDEFLETACNGSIHSSQKA
LAASVTPFQSSEVRGTQLADRIQNYMTSTGATKVNIIGHSQGGIDARKAAAVLRARYGRQVVHVMISVSSPHRGSPTAKY
ILDLGPGVTSVVNALAKLFGNTIYGSGNDGIAAAKQLVYNDYSSTDGVTTGMKAFNNNYNVSTNTANYWGSIITAQDSIN
TNPALYLLKEGFYNIDGDGYCVDDCDNDGAAGKGDGTRGNNDDDGLVGINSQQMGYRLQYNECLICFDSITVNSTLGYVS
NLNAPTSAQMTSKSSVVSQDHLDVVGVPPDTFDEEEFYASILEFIVTKGG

Sequences:

>Translated_370_residues
MNSKKKHLVCLLVLLLVTTGVHAGARKTVYPVVFAHGLSGFDNLLGYYYFGNDYGTFVGDPCDEFLETACNGSIHSSQKA
LAASVTPFQSSEVRGTQLADRIQNYMTSTGATKVNIIGHSQGGIDARKAAAVLRARYGRQVVHVMISVSSPHRGSPTAKY
ILDLGPGVTSVVNALAKLFGNTIYGSGNDGIAAAKQLVYNDYSSTDGVTTGMKAFNNNYNVSTNTANYWGSIITAQDSIN
TNPALYLLKEGFYNIDGDGYCVDDCDNDGAAGKGDGTRGNNDDDGLVGINSQQMGYRLQYNECLICFDSITVNSTLGYVS
NLNAPTSAQMTSKSSVVSQDHLDVVGVPPDTFDEEEFYASILEFIVTKGG
>Mature_370_residues
MNSKKKHLVCLLVLLLVTTGVHAGARKTVYPVVFAHGLSGFDNLLGYYYFGNDYGTFVGDPCDEFLETACNGSIHSSQKA
LAASVTPFQSSEVRGTQLADRIQNYMTSTGATKVNIIGHSQGGIDARKAAAVLRARYGRQVVHVMISVSSPHRGSPTAKY
ILDLGPGVTSVVNALAKLFGNTIYGSGNDGIAAAKQLVYNDYSSTDGVTTGMKAFNNNYNVSTNTANYWGSIITAQDSIN
TNPALYLLKEGFYNIDGDGYCVDDCDNDGAAGKGDGTRGNNDDDGLVGINSQQMGYRLQYNECLICFDSITVNSTLGYVS
NLNAPTSAQMTSKSSVVSQDHLDVVGVPPDTFDEEEFYASILEFIVTKGG

Specific function: Catalyzes the hydrolysis of triglycerides. Catalyzes the synthesis of macrocyclic lactones in anhydrous organic solvents [H]

COG id: COG1075

COG function: function code R; Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold

Gene ontology:

Cell location: Cell surface. Secreted, extracellular space. Note=During early stationary growth phase about 10% of the enzyme molecules remain cell-bound while about 90% are released into the growth medium [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Pseudomonas lipase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.1.1.3 [H]

Molecular weight: Translated: 39494; Mature: 39494

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS00120 LIPASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSKKKHLVCLLVLLLVTTGVHAGARKTVYPVVFAHGLSGFDNLLGYYYFGNDYGTFVGD
CCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCHHHHEEEEEECCCCCCCCCC
PCDEFLETACNGSIHSSQKALAASVTPFQSSEVRGTQLADRIQNYMTSTGATKVNIIGHS
CHHHHHHHHCCCCCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECC
QGGIDARKAAAVLRARYGRQVVHVMISVSSPHRGSPTAKYILDLGPGVTSVVNALAKLFG
CCCCHHHHHHHHHHHHHCCEEEEEEEEECCCCCCCCCCEEEEECCCCHHHHHHHHHHHHC
NTIYGSGNDGIAAAKQLVYNDYSSTDGVTTGMKAFNNNYNVSTNTANYWGSIITAQDSIN
CCEECCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCEECCCHHHCCEEEEECCCCC
TNPALYLLKEGFYNIDGDGYCVDDCDNDGAAGKGDGTRGNNDDDGLVGINSQQMGYRLQY
CCCEEEEEECCCEECCCCCEECCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCEEEEC
NECLICFDSITVNSTLGYVSNLNAPTSAQMTSKSSVVSQDHLDVVGVPPDTFDEEEFYAS
CCEEEEEECEEECCHHHHHHCCCCCCCHHHCCHHHHHCCCCCEEEECCCCCCCHHHHHHH
ILEFIVTKGG
HHHHHHCCCC
>Mature Secondary Structure
MNSKKKHLVCLLVLLLVTTGVHAGARKTVYPVVFAHGLSGFDNLLGYYYFGNDYGTFVGD
CCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCHHHHEEEEEECCCCCCCCCC
PCDEFLETACNGSIHSSQKALAASVTPFQSSEVRGTQLADRIQNYMTSTGATKVNIIGHS
CHHHHHHHHCCCCCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECC
QGGIDARKAAAVLRARYGRQVVHVMISVSSPHRGSPTAKYILDLGPGVTSVVNALAKLFG
CCCCHHHHHHHHHHHHHCCEEEEEEEEECCCCCCCCCCEEEEECCCCHHHHHHHHHHHHC
NTIYGSGNDGIAAAKQLVYNDYSSTDGVTTGMKAFNNNYNVSTNTANYWGSIITAQDSIN
CCEECCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCEECCCHHHCCEEEEECCCCC
TNPALYLLKEGFYNIDGDGYCVDDCDNDGAAGKGDGTRGNNDDDGLVGINSQQMGYRLQY
CCCEEEEEECCCEECCCCCEECCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCEEEEC
NECLICFDSITVNSTLGYVSNLNAPTSAQMTSKSSVVSQDHLDVVGVPPDTFDEEEFYAS
CCEEEEEECEEECCHHHHHHCCCCCCCHHHCCHHHHHCCCCCEEEECCCCCCCHHHHHHH
ILEFIVTKGG
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1512563; 1632642; 1576157; 10984043; 1748875; 11133953 [H]