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The map label for this gene is yrbG [C]

Identifier: 183220103

GI number: 183220103

Start: 698824

End: 699858

Strand: Reverse

Name: yrbG [C]

Synonym: LEPBI_I0691

Alternate gene names: 183220103

Gene position: 699858-698824 (Counterclockwise)

Preceding gene: 183220105

Following gene: 183220100

Centisome position: 19.44

GC content: 47.15

Gene sequence:

>1035_bases
ATGGATGCATTTCTGACTGCAACTTTTCAAACCCTTCCCTTACCCATACTCATTCTCGTCATCATCGGCTCCATCCTTGT
CCTCGGGAAAGCCGCCGATGTTTTAGTGGACGAAGCCGTCTCCCTTTCAACGAGATGGGGAGTACCCAAGATGATCATTG
GGGCAACGATTGTCAGTTTAGGGACCACTCTCCCTGAAGTCTCCGTTTCCGTTCTTGCGGCACTCGAAGGGAATCCAGGC
ATTGCCCTGGGAAATGCGGTGGGTTCCATCATCTGTGATACAGGTCTCATCCTTGGGATCGCCATTCTCATCTCACCACC
TGACATCGACAAACGTCTTGTGAACCGCCAAGGTTGGATCCAAGTGCTCAGTGGGTTTTTACTGGTATTTGCTGCACTAC
CCTGGTCAAACCTTAGTTCTGTTTTTTCCACAGGTGGGCGGATCGACCAAGGAACAGGCGTTGTCTTTTTAATCTTACTT
GGAGTTTACATTTACCTTAGCATCCGTTGGTCAAGGTCAAAACCTGGCGAACTCGAAGCAGGGATTGATGACACAACCGA
ATACGACGAATCTCCATTTTGGATTGTGTTGTTAAAACTAGTGGTGGCGATCACCCTTGTGATATTGTCTTCAAAAGTTC
TCATCCCTTCCGTCCAAGAAACAGCGGTTCGGTTGTCGATTCCTGAGTCCATTATTGGTGCCACTCTTGTTGCCTTTGGA
ACCAGTTTACCAGAACTTGTGACAGCCATCCAAGCCTCAAGGCGTGGCCACTCCGAACTTGCTGTGGGAAATATCATCGG
TGCTGATATTTTAAATGTGCTCTTTGTCTCAGGTGCCGCTGCGGCTGTGACTCGGACTGGCCTCGAAGCTCCAGTGAGTT
TTTTCAGTTTTTATTTTCCTTCCATGCTCACCGTTTTGATTTTATTCCGCCTTGGGATTGTATTCTCAAAAGACAAAATC
AAACGCCCGTTTGGTGTGTTTTTACTCATCATTTATGCAATGGCGACAATTGCAGGATTTATCTTCAAAGGATAA

Upstream 100 bases:

>100_bases
CATTCGTGGTTCTCCGTAACTAGGCGAAAAAAAACCGAGAGCCCCAAGCCAAAGAAAGAGTCGCAGTCGAAGTAAGTAAT
CCATATTCTGACCTTTATCC

Downstream 100 bases:

>100_bases
ATTTGAAATTCACCTCCACCTCTTCCTTTTTCGATAGGAAGTTGGTGGATTTTTGTTTTCTCCATTCCTCATAACTCAAG
ATTTTTTTTTCAATCCATTG

Product: putative cation exchanger

Products: Na (I) [Cytoplasm]; Ca (II) [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MDAFLTATFQTLPLPILILVIIGSILVLGKAADVLVDEAVSLSTRWGVPKMIIGATIVSLGTTLPEVSVSVLAALEGNPG
IALGNAVGSIICDTGLILGIAILISPPDIDKRLVNRQGWIQVLSGFLLVFAALPWSNLSSVFSTGGRIDQGTGVVFLILL
GVYIYLSIRWSRSKPGELEAGIDDTTEYDESPFWIVLLKLVVAITLVILSSKVLIPSVQETAVRLSIPESIIGATLVAFG
TSLPELVTAIQASRRGHSELAVGNIIGADILNVLFVSGAAAAVTRTGLEAPVSFFSFYFPSMLTVLILFRLGIVFSKDKI
KRPFGVFLLIIYAMATIAGFIFKG

Sequences:

>Translated_344_residues
MDAFLTATFQTLPLPILILVIIGSILVLGKAADVLVDEAVSLSTRWGVPKMIIGATIVSLGTTLPEVSVSVLAALEGNPG
IALGNAVGSIICDTGLILGIAILISPPDIDKRLVNRQGWIQVLSGFLLVFAALPWSNLSSVFSTGGRIDQGTGVVFLILL
GVYIYLSIRWSRSKPGELEAGIDDTTEYDESPFWIVLLKLVVAITLVILSSKVLIPSVQETAVRLSIPESIIGATLVAFG
TSLPELVTAIQASRRGHSELAVGNIIGADILNVLFVSGAAAAVTRTGLEAPVSFFSFYFPSMLTVLILFRLGIVFSKDKI
KRPFGVFLLIIYAMATIAGFIFKG
>Mature_344_residues
MDAFLTATFQTLPLPILILVIIGSILVLGKAADVLVDEAVSLSTRWGVPKMIIGATIVSLGTTLPEVSVSVLAALEGNPG
IALGNAVGSIICDTGLILGIAILISPPDIDKRLVNRQGWIQVLSGFLLVFAALPWSNLSSVFSTGGRIDQGTGVVFLILL
GVYIYLSIRWSRSKPGELEAGIDDTTEYDESPFWIVLLKLVVAITLVILSSKVLIPSVQETAVRLSIPESIIGATLVAFG
TSLPELVTAIQASRRGHSELAVGNIIGADILNVLFVSGAAAAVTRTGLEAPVSFFSFYFPSMLTVLILFRLGIVFSKDKI
KRPFGVFLLIIYAMATIAGFIFKG

Specific function: Unknown

COG id: COG0530

COG function: function code P; Ca2+/Na+ antiporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium/potassium/calcium exchanger family [H]

Homologues:

Organism=Escherichia coli, GI1789587, Length=308, Percent_Identity=32.4675324675325, Blast_Score=99, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004481
- InterPro:   IPR004837 [H]

Pfam domain/function: PF01699 Na_Ca_ex [H]

EC number: NA

Molecular weight: Translated: 36485; Mature: 36485

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAFLTATFQTLPLPILILVIIGSILVLGKAADVLVDEAVSLSTRWGVPKMIIGATIVSL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
GTTLPEVSVSVLAALEGNPGIALGNAVGSIICDTGLILGIAILISPPDIDKRLVNRQGWI
CCCCHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
QVLSGFLLVFAALPWSNLSSVFSTGGRIDQGTGVVFLILLGVYIYLSIRWSRSKPGELEA
HHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHEEEEECCCCCCCCCC
GIDDTTEYDESPFWIVLLKLVVAITLVILSSKVLIPSVQETAVRLSIPESIIGATLVAFG
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHEEEECCHHHHHHHHHHHC
TSLPELVTAIQASRRGHSELAVGNIIGADILNVLFVSGAAAAVTRTGLEAPVSFFSFYFP
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHCHHHHHHHHHHHHH
SMLTVLILFRLGIVFSKDKIKRPFGVFLLIIYAMATIAGFIFKG
HHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDAFLTATFQTLPLPILILVIIGSILVLGKAADVLVDEAVSLSTRWGVPKMIIGATIVSL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
GTTLPEVSVSVLAALEGNPGIALGNAVGSIICDTGLILGIAILISPPDIDKRLVNRQGWI
CCCCHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
QVLSGFLLVFAALPWSNLSSVFSTGGRIDQGTGVVFLILLGVYIYLSIRWSRSKPGELEA
HHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHEEEEECCCCCCCCCC
GIDDTTEYDESPFWIVLLKLVVAITLVILSSKVLIPSVQETAVRLSIPESIIGATLVAFG
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHEEEECCHHHHHHHHHHHC
TSLPELVTAIQASRRGHSELAVGNIIGADILNVLFVSGAAAAVTRTGLEAPVSFFSFYFP
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHCHHHHHHHHHHHHH
SMLTVLILFRLGIVFSKDKIKRPFGVFLLIIYAMATIAGFIFKG
HHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; Ca (II) [Cytoplasm] [C]

Specific reaction: Na (I) [Periplasm] + Ca (II) [Cytoplasm] = Na (I) [Cytoplasm] + Ca (II) [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]