| Definition | Leptospira biflexa serovar Patoc strain 'Patoc 1 (Paris)' chromosome chromosome I, complete sequence. |
|---|---|
| Accession | NC_010602 |
| Length | 3,599,677 |
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The map label for this gene is adiA [H]
Identifier: 183220105
GI number: 183220105
Start: 700693
End: 702960
Strand: Reverse
Name: adiA [H]
Synonym: LEPBI_I0693
Alternate gene names: 183220105
Gene position: 702960-700693 (Counterclockwise)
Preceding gene: 183220106
Following gene: 183220103
Centisome position: 19.53
GC content: 44.18
Gene sequence:
>2268_bases ATGTATCAAAACGGTATCGTACAATTTCCTATCATCATCATTGATGAAGATTTTCGTTCCGAAAATGCCAGTGGTCTTGG CATTCGAGCAATTGCAAAGGCCTTGGAAGGCGAAGGAATCGAAGTTCTGGGTGTCACCAGTTACGGAGATCTTACTAGTT TTGTACAACAACAGAGTCGGGCTTGCGGATTCATTCTCTCCATTGACGATGAAGAGTTCACTCCCGAAACAGAAGGGGAA GTGCCCGATGCCCTTCGCCAACTCAAAGACTTTGTCACCCAAGTGCGTCACAGAAACGCCGACATACCACTGTTTTTGTA TGGGGAGACAAGGACTAGTCGCCATATTCCGAATAGTATCCTCAAAGAACTCCATGGCTTCATTCATATGTTTGAAGACA CACCAGAGTTTATGGCACGCGCCATCCACCGAGAAGTAAAATCATACTTAGATAGCCTTCCTCCTCCTTTCTTCCGAGCT CTCACCCAATATGCACATGATGGAAGTTATAGTTGGCACTGCCCTGGGCACTCTGGTGGCGTTGCCTTTTTAAAAAGCCC TGTGGGACAAATGTTCCACCAGTTTTTTGGTGAGAACATGTTACGAGCTGACGTGTGTAATGCGGTTGATGAACTCGGAC AACTCCTAGACCATACAGGCCCCATTTCTGCCAGTGAAAGAAACGCAGCACGTATCTTCCAATGTGATAGTTTGTATTTT GTGACAAATGGAACATCTACTTCCAATAAAATTGTATGGCATAGCACCGTGGCTCCTGGAGACGTTGTGATCGTTGACCG CAACTGTCACAAAAGTATCTTACATGCCATCACAATGACTGGTGCCATCCCAGTTTTCCTTATGCCAACACGAAACCATT TTGGAATCATTGGACCTATCCCAAAATCAGAATTCACTTGGGAAAACATTAAAAAGAAAATCGCAGAACACCCGTTTGCC AAAGAAGTCAAAGGGAATCCTAGAATTCTTACCATCACACAAAGTACATATGATGGAATTTTATACAATGTCGAAGACAT TAAATCAGAGTTAGATGGTAAAATCTCAACACTTCATTTTGATGAAGCATGGTTACCACACGCATCGTTTCATCGTTTTT ATACTGGGATGCATGCGATTGGATCTGACAGACCACGTCCAAAAGAAAGTATGATCTTTGCCACGCAGTCCACACACAAA CTCTTAGCAGGTTTATCACAAGCAAGTCAGATCCTTGTCCAAAACAGTGAAAAAGAGACCTTAGATCGAAATTTATTCAA CGAAGCCTTTTTAATGCACACAAGCACAAGTCCACAATATGCCATCATCGCTTCTTGTGATGTGGCGGCAGCCATGATGG AATCTCCTGGTGGGAATGCTCTTGTGGAAGAGTCCATCGAGGAAGCATTGGATTTCCGGCGAGCCATGCGCAAAGTAGGT TTGGAATTAGAAGAAGATTGGTGGTTCAGTGTTTGGGGTCCAGAAGCCCTTGCCGATGAAGGTGCGGGCGAAAGGGATGA ATGGATCCTAAAAGCAAACGATCGTTGGCACGGATTTGGTGACATTGCAGAAGGATTTAATATGTTAGATCCGATCAAGG CAACTGTCATCACTCCTGGTATGAGTGTGGAGGGGGAATTTGCGGATTGGGGAATCCCTGCGCTGATCCTCACCAAATAC TTAGCAGAACATGGAATCATCGTCGAAAAAACTGGACTCTATAGTTTCTTTATCATGTTTACGATCGGGATCACAAAGGG TCGTTGGAATACAATGGTCACTGAATTACAACAATTCAAAGATGATTATGATTCGAACCAACCTCTCTGGAGGGTGATGC CAAAGTTTACGGTAGCCTATCCGAAATACGATCGGATTGGATTACGAGATCTTTGCCAATCCATGCATGAAGTGTATCGG GCAAATAACATTTCCCACCTAACAACGGAAATGTATTTGAGTCCCATGATCCCTGCGATGAAGCCTTCAGAGGCATTCGC AAAAATGGCACACCGTGACATTGAACGAGTTCCGATTGATGAATTGGAAGGAAGGATTACGTCTGTCCTTCTCACTCCCT ACCCACCCGGAATCCCTCTCCTCATCCCTGGCGAAAAGTTCAATACGACCATCATTCGGTATTTACAATTTGCTCGTGAG TTTAATACAAAGTTCCCTGGGTTTGAAACAGACATCCATGGCCTCGTGGAAGAAAAATCGGAGACAGGACACTTATCTTA CTTTGTAGATTGTGTGATGGAATCTTAA
Upstream 100 bases:
>100_bases CAACACAGTTGAGATGGAGTATTATAAATACCTTCCGAAAAAACGAGTTTAGAAACTAAAATCATTTGATTCTCTGTGGG TCACTCTTCCTATGGAGTTG
Downstream 100 bases:
>100_bases AAAAAAGAATCTAAGATCGGAATGGTCCCTAGAACCAGACGGTGGCGACAAAAAAACCCCTCTGGTTCTAGAAGTTCAAT GGAAACTGATTACCTGCATT
Product: lysine decarboxylase
Products: NA
Alternate protein names: ADC [H]
Number of amino acids: Translated: 755; Mature: 755
Protein sequence:
>755_residues MYQNGIVQFPIIIIDEDFRSENASGLGIRAIAKALEGEGIEVLGVTSYGDLTSFVQQQSRACGFILSIDDEEFTPETEGE VPDALRQLKDFVTQVRHRNADIPLFLYGETRTSRHIPNSILKELHGFIHMFEDTPEFMARAIHREVKSYLDSLPPPFFRA LTQYAHDGSYSWHCPGHSGGVAFLKSPVGQMFHQFFGENMLRADVCNAVDELGQLLDHTGPISASERNAARIFQCDSLYF VTNGTSTSNKIVWHSTVAPGDVVIVDRNCHKSILHAITMTGAIPVFLMPTRNHFGIIGPIPKSEFTWENIKKKIAEHPFA KEVKGNPRILTITQSTYDGILYNVEDIKSELDGKISTLHFDEAWLPHASFHRFYTGMHAIGSDRPRPKESMIFATQSTHK LLAGLSQASQILVQNSEKETLDRNLFNEAFLMHTSTSPQYAIIASCDVAAAMMESPGGNALVEESIEEALDFRRAMRKVG LELEEDWWFSVWGPEALADEGAGERDEWILKANDRWHGFGDIAEGFNMLDPIKATVITPGMSVEGEFADWGIPALILTKY LAEHGIIVEKTGLYSFFIMFTIGITKGRWNTMVTELQQFKDDYDSNQPLWRVMPKFTVAYPKYDRIGLRDLCQSMHEVYR ANNISHLTTEMYLSPMIPAMKPSEAFAKMAHRDIERVPIDELEGRITSVLLTPYPPGIPLLIPGEKFNTTIIRYLQFARE FNTKFPGFETDIHGLVEEKSETGHLSYFVDCVMES
Sequences:
>Translated_755_residues MYQNGIVQFPIIIIDEDFRSENASGLGIRAIAKALEGEGIEVLGVTSYGDLTSFVQQQSRACGFILSIDDEEFTPETEGE VPDALRQLKDFVTQVRHRNADIPLFLYGETRTSRHIPNSILKELHGFIHMFEDTPEFMARAIHREVKSYLDSLPPPFFRA LTQYAHDGSYSWHCPGHSGGVAFLKSPVGQMFHQFFGENMLRADVCNAVDELGQLLDHTGPISASERNAARIFQCDSLYF VTNGTSTSNKIVWHSTVAPGDVVIVDRNCHKSILHAITMTGAIPVFLMPTRNHFGIIGPIPKSEFTWENIKKKIAEHPFA KEVKGNPRILTITQSTYDGILYNVEDIKSELDGKISTLHFDEAWLPHASFHRFYTGMHAIGSDRPRPKESMIFATQSTHK LLAGLSQASQILVQNSEKETLDRNLFNEAFLMHTSTSPQYAIIASCDVAAAMMESPGGNALVEESIEEALDFRRAMRKVG LELEEDWWFSVWGPEALADEGAGERDEWILKANDRWHGFGDIAEGFNMLDPIKATVITPGMSVEGEFADWGIPALILTKY LAEHGIIVEKTGLYSFFIMFTIGITKGRWNTMVTELQQFKDDYDSNQPLWRVMPKFTVAYPKYDRIGLRDLCQSMHEVYR ANNISHLTTEMYLSPMIPAMKPSEAFAKMAHRDIERVPIDELEGRITSVLLTPYPPGIPLLIPGEKFNTTIIRYLQFARE FNTKFPGFETDIHGLVEEKSETGHLSYFVDCVMES >Mature_755_residues MYQNGIVQFPIIIIDEDFRSENASGLGIRAIAKALEGEGIEVLGVTSYGDLTSFVQQQSRACGFILSIDDEEFTPETEGE VPDALRQLKDFVTQVRHRNADIPLFLYGETRTSRHIPNSILKELHGFIHMFEDTPEFMARAIHREVKSYLDSLPPPFFRA LTQYAHDGSYSWHCPGHSGGVAFLKSPVGQMFHQFFGENMLRADVCNAVDELGQLLDHTGPISASERNAARIFQCDSLYF VTNGTSTSNKIVWHSTVAPGDVVIVDRNCHKSILHAITMTGAIPVFLMPTRNHFGIIGPIPKSEFTWENIKKKIAEHPFA KEVKGNPRILTITQSTYDGILYNVEDIKSELDGKISTLHFDEAWLPHASFHRFYTGMHAIGSDRPRPKESMIFATQSTHK LLAGLSQASQILVQNSEKETLDRNLFNEAFLMHTSTSPQYAIIASCDVAAAMMESPGGNALVEESIEEALDFRRAMRKVG LELEEDWWFSVWGPEALADEGAGERDEWILKANDRWHGFGDIAEGFNMLDPIKATVITPGMSVEGEFADWGIPALILTKY LAEHGIIVEKTGLYSFFIMFTIGITKGRWNTMVTELQQFKDDYDSNQPLWRVMPKFTVAYPKYDRIGLRDLCQSMHEVYR ANNISHLTTEMYLSPMIPAMKPSEAFAKMAHRDIERVPIDELEGRITSVLLTPYPPGIPLLIPGEKFNTTIIRYLQFARE FNTKFPGFETDIHGLVEEKSETGHLSYFVDCVMES
Specific function: ADC can be found in two forms:biodegradative and biosynthetic. The biodegradative form may play a role in regulating pH by consuming proteins [H]
COG id: COG1982
COG function: function code E; Arginine/lysine/ornithine decarboxylases
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-I family [H]
Homologues:
Organism=Escherichia coli, GI221142684, Length=748, Percent_Identity=36.2299465240642, Blast_Score=513, Evalue=1e-146, Organism=Escherichia coli, GI1790573, Length=711, Percent_Identity=37.6933895921238, Blast_Score=507, Evalue=1e-144, Organism=Escherichia coli, GI1786384, Length=718, Percent_Identity=37.4651810584958, Blast_Score=492, Evalue=1e-140, Organism=Escherichia coli, GI87082193, Length=731, Percent_Identity=31.6005471956224, Blast_Score=354, Evalue=1e-98, Organism=Escherichia coli, GI1786909, Length=660, Percent_Identity=32.8787878787879, Blast_Score=350, Evalue=2e-97,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR005308 - InterPro: IPR011193 - InterPro: IPR000310 - InterPro: IPR008286 - InterPro: IPR015424 - InterPro: IPR015421 - InterPro: IPR015422 [H]
Pfam domain/function: PF01276 OKR_DC_1; PF03711 OKR_DC_1_C; PF03709 OKR_DC_1_N [H]
EC number: =4.1.1.19 [H]
Molecular weight: Translated: 85144; Mature: 85144
Theoretical pI: Translated: 5.20; Mature: 5.20
Prosite motif: PS00703 OKR_DC_1
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.1 %Cys (Translated Protein) 3.2 %Met (Translated Protein) 4.2 %Cys+Met (Translated Protein) 1.1 %Cys (Mature Protein) 3.2 %Met (Mature Protein) 4.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MYQNGIVQFPIIIIDEDFRSENASGLGIRAIAKALEGEGIEVLGVTSYGDLTSFVQQQSR CCCCCEEEEEEEEEECCCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHC ACGFILSIDDEEFTPETEGEVPDALRQLKDFVTQVRHRNADIPLFLYGETRTSRHIPNSI CCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHH LKELHGFIHMFEDTPEFMARAIHREVKSYLDSLPPPFFRALTQYAHDGSYSWHCPGHSGG HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEECCCCCCC VAFLKSPVGQMFHQFFGENMLRADVCNAVDELGQLLDHTGPISASERNAARIFQCDSLYF HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCEEE VTNGTSTSNKIVWHSTVAPGDVVIVDRNCHKSILHAITMTGAIPVFLMPTRNHFGIIGPI EECCCCCCCEEEEEECCCCCCEEEECCCHHHHHHHHHHHHCCCEEEEEECCCCCEEECCC PKSEFTWENIKKKIAEHPFAKEVKGNPRILTITQSTYDGILYNVEDIKSELDGKISTLHF CCCCCCHHHHHHHHHHCCCHHHCCCCCEEEEEECCCCCCEEEEHHHHHHHHCCCEEEEEE DEAWLPHASFHRFYTGMHAIGSDRPRPKESMIFATQSTHKLLAGLSQASQILVQNSEKET CCCCCCCHHHHHHHHHHHHHCCCCCCCCHHEEEEECHHHHHHHHHHHHHHHHHCCCCHHH LDRNLFNEAFLMHTSTSPQYAIIASCDVAAAMMESPGGNALVEESIEEALDFRRAMRKVG HHHHHHHHEEEEEECCCCCEEEEEECHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHC LELEEDWWFSVWGPEALADEGAGERDEWILKANDRWHGFGDIAEGFNMLDPIKATVITPG CEECCCCEEEECCCHHHHCCCCCCCCCEEEEECCCCCCCCCHHHCCCCCCCCHHEEECCC MSVEGEFADWGIPALILTKYLAEHGIIVEKTGLYSFFIMFTIGITKGRWNTMVTELQQFK CCCCCCCCCCCCHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHCCCCCHHHHHHHHHHHH DDYDSNQPLWRVMPKFTVAYPKYDRIGLRDLCQSMHEVYRANNISHLTTEMYLSPMIPAM HHCCCCCCHHHHCCCCEEECCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCC KPSEAFAKMAHRDIERVPIDELEGRITSVLLTPYPPGIPLLIPGEKFNTTIIRYLQFARE CCHHHHHHHHHHHHHCCCHHHHCCCEEEEEECCCCCCCCEEECCCCHHHHHHHHHHHHHH FNTKFPGFETDIHGLVEEKSETGHLSYFVDCVMES HCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHCC >Mature Secondary Structure MYQNGIVQFPIIIIDEDFRSENASGLGIRAIAKALEGEGIEVLGVTSYGDLTSFVQQQSR CCCCCEEEEEEEEEECCCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHC ACGFILSIDDEEFTPETEGEVPDALRQLKDFVTQVRHRNADIPLFLYGETRTSRHIPNSI CCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHH LKELHGFIHMFEDTPEFMARAIHREVKSYLDSLPPPFFRALTQYAHDGSYSWHCPGHSGG HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEECCCCCCC VAFLKSPVGQMFHQFFGENMLRADVCNAVDELGQLLDHTGPISASERNAARIFQCDSLYF HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCEEE VTNGTSTSNKIVWHSTVAPGDVVIVDRNCHKSILHAITMTGAIPVFLMPTRNHFGIIGPI EECCCCCCCEEEEEECCCCCCEEEECCCHHHHHHHHHHHHCCCEEEEEECCCCCEEECCC PKSEFTWENIKKKIAEHPFAKEVKGNPRILTITQSTYDGILYNVEDIKSELDGKISTLHF CCCCCCHHHHHHHHHHCCCHHHCCCCCEEEEEECCCCCCEEEEHHHHHHHHCCCEEEEEE DEAWLPHASFHRFYTGMHAIGSDRPRPKESMIFATQSTHKLLAGLSQASQILVQNSEKET CCCCCCCHHHHHHHHHHHHHCCCCCCCCHHEEEEECHHHHHHHHHHHHHHHHHCCCCHHH LDRNLFNEAFLMHTSTSPQYAIIASCDVAAAMMESPGGNALVEESIEEALDFRRAMRKVG HHHHHHHHEEEEEECCCCCEEEEEECHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHC LELEEDWWFSVWGPEALADEGAGERDEWILKANDRWHGFGDIAEGFNMLDPIKATVITPG CEECCCCEEEECCCHHHHCCCCCCCCCEEEEECCCCCCCCCHHHCCCCCCCCHHEEECCC MSVEGEFADWGIPALILTKYLAEHGIIVEKTGLYSFFIMFTIGITKGRWNTMVTELQQFK CCCCCCCCCCCCHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHCCCCCHHHHHHHHHHHH DDYDSNQPLWRVMPKFTVAYPKYDRIGLRDLCQSMHEVYRANNISHLTTEMYLSPMIPAM HHCCCCCCHHHHCCCCEEECCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCC KPSEAFAKMAHRDIERVPIDELEGRITSVLLTPYPPGIPLLIPGEKFNTTIIRYLQFARE CCHHHHHHHHHHHHHCCCHHHHCCCEEEEEECCCCCCCCEEECCCCHHHHHHHHHHHHHH FNTKFPGFETDIHGLVEEKSETGHLSYFVDCVMES HCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 8383109; 7610040; 9278503; 2830169; 4204273 [H]