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The map label for this gene is yebA [H]

Identifier: 183220041

GI number: 183220041

Start: 629996

End: 631549

Strand: Reverse

Name: yebA [H]

Synonym: LEPBI_I0627

Alternate gene names: 183220041

Gene position: 631549-629996 (Counterclockwise)

Preceding gene: 183220042

Following gene: 183220040

Centisome position: 17.54

GC content: 38.16

Gene sequence:

>1554_bases
ATGAAAACTCTACAAACTGTCTTTCTCACATTGATTCTAACATTATGTAACATTTCTATTTGGTCACAATCGAATTTGGA
AGACCGAGACAAAGAAAGACAATCTGGACTCATCAAAACCAATCAAAAAAAACAAGAAGAAATCTTACAAAAATACAACG
ACTTTGTCTCAAAAGTACAAAGCCGTTTTCCTGGATTAAAAATATCTTCCTCCCCTATCGACTTAAAAATGGCAGAGGGT
ATATCCGATCACAACAATGCTCCTGGAGCTCTAGATAAAAAACCAAAATCCATTACAGCAATTGCATCCGATCATTTTTA
CCTACAACTCGAACCCTCAATCCAACCTAATGCACGTTCGCAGGTAAAAATCAAAAAAGGTGATCCTTTGGAAGTTGTTT
TAGTATTAAAGCAAGATGTGACTGACAAAAAAGAAGGTTCTCATTGGGTTTTGGTTCGAACAAAATCAAAAAAAGAAGGA
TACATCACACAAGATTTATTACAACCTACGAAACCTACTGTAAAATCTAGAAACACAGAAGGAAATTCCTTAGACCTGTC
TGCTTTACCTTCCCGAACCACAAACGCTAATGTAACAGATGTCAAAAAAGGCAAAGAAATGTGGGTGAATGCAAGTTCCC
TAAATATGCGAGGGGAACCTGATGTAAATGGGTATGTGATCGCAAGGTTACCCAAAGGCCAAAAAGTTTCCATTGAAAGT
TCCACAACTAACGAAGAAACAATCGATGGCATTTCTTCCAATTGGTATCAAGTCTCATCCGCATATGGGAATGGTTGGGT
GTTTGGTGGGTATTTGAGCACATCCGAAGTAGTTTCTTATGAAATACAACCTGGAGAAACATCGTTTCCACAAGAGAATC
CAGATGAATTAAAAACAGGTGAAAAACGATTTGTTAGATCAACAAATTTAAGAATGAGAGACGAACCAAATGATTATGGT
TCTGTCATTACTTCAATCCCAGGCGATGAAAAATTAAAAATATTAGATATAAAAAAAGAAATCGAAACCATCGCGGGTGT
TCGATCAAAATGGATCTATGTGAATTGGAATGATGAATGGGAAGGATGGGTCTTTGGTGGATTTGTATCCAAAGAACGTG
GTCCACTTGTCGATAGTGATGATATTTCAAAATATTTCCAAATCCCAGTCGATAACGAACGCTATGTGTCTTCAAGTTTT
GGAACAAGAGTTGATCCAGTCACAGGAAAAATAGGGGCATTCCATTCAGGAATTGATTTACCTGCACCGATTGGCACTCC
CATCAAAGCTGTTAGCGATGGGAAAGTATGGCGAACCATTACAACTAGCGGTGGTTATGGGGTATTAACAATCATAAGCC
ATAAAAATAATATTTTTACCTATTATGCGCATCAAAGTGAGCGACAAGTAAAAGAAGGTGACACAGTCCGCTCCGGTGAT
ATCATTGGTCAGGTAGGAAACACAGGTAAGTCTACCGGTCCTCATTTACATTTTGAAGTTAGGAAAGGCCCTGACCAACA
AGCGTTGGATCCAGGAGCTTATTTACCCAAATGA

Upstream 100 bases:

>100_bases
AGAGTTTATCTCTTTTTTTCTCACGCCACTCCTGCCTGAAGAGGACTGAACAAAAAACCTTGACCAAAGCCAAATGATTT
GGTTATTTTAAGTTTGTTTT

Downstream 100 bases:

>100_bases
AAATTAAAATCAGCTACATCAATCTTCTTCTTTCTCTTTTCTTTTTCACGAATCTAACCCTGCTCGCGGAGGAAACGATT
CCACCGGCTTCGGATGTAAC

Product: M23 family metalloendopeptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 517; Mature: 517

Protein sequence:

>517_residues
MKTLQTVFLTLILTLCNISIWSQSNLEDRDKERQSGLIKTNQKKQEEILQKYNDFVSKVQSRFPGLKISSSPIDLKMAEG
ISDHNNAPGALDKKPKSITAIASDHFYLQLEPSIQPNARSQVKIKKGDPLEVVLVLKQDVTDKKEGSHWVLVRTKSKKEG
YITQDLLQPTKPTVKSRNTEGNSLDLSALPSRTTNANVTDVKKGKEMWVNASSLNMRGEPDVNGYVIARLPKGQKVSIES
STTNEETIDGISSNWYQVSSAYGNGWVFGGYLSTSEVVSYEIQPGETSFPQENPDELKTGEKRFVRSTNLRMRDEPNDYG
SVITSIPGDEKLKILDIKKEIETIAGVRSKWIYVNWNDEWEGWVFGGFVSKERGPLVDSDDISKYFQIPVDNERYVSSSF
GTRVDPVTGKIGAFHSGIDLPAPIGTPIKAVSDGKVWRTITTSGGYGVLTIISHKNNIFTYYAHQSERQVKEGDTVRSGD
IIGQVGNTGKSTGPHLHFEVRKGPDQQALDPGAYLPK

Sequences:

>Translated_517_residues
MKTLQTVFLTLILTLCNISIWSQSNLEDRDKERQSGLIKTNQKKQEEILQKYNDFVSKVQSRFPGLKISSSPIDLKMAEG
ISDHNNAPGALDKKPKSITAIASDHFYLQLEPSIQPNARSQVKIKKGDPLEVVLVLKQDVTDKKEGSHWVLVRTKSKKEG
YITQDLLQPTKPTVKSRNTEGNSLDLSALPSRTTNANVTDVKKGKEMWVNASSLNMRGEPDVNGYVIARLPKGQKVSIES
STTNEETIDGISSNWYQVSSAYGNGWVFGGYLSTSEVVSYEIQPGETSFPQENPDELKTGEKRFVRSTNLRMRDEPNDYG
SVITSIPGDEKLKILDIKKEIETIAGVRSKWIYVNWNDEWEGWVFGGFVSKERGPLVDSDDISKYFQIPVDNERYVSSSF
GTRVDPVTGKIGAFHSGIDLPAPIGTPIKAVSDGKVWRTITTSGGYGVLTIISHKNNIFTYYAHQSERQVKEGDTVRSGD
IIGQVGNTGKSTGPHLHFEVRKGPDQQALDPGAYLPK
>Mature_517_residues
MKTLQTVFLTLILTLCNISIWSQSNLEDRDKERQSGLIKTNQKKQEEILQKYNDFVSKVQSRFPGLKISSSPIDLKMAEG
ISDHNNAPGALDKKPKSITAIASDHFYLQLEPSIQPNARSQVKIKKGDPLEVVLVLKQDVTDKKEGSHWVLVRTKSKKEG
YITQDLLQPTKPTVKSRNTEGNSLDLSALPSRTTNANVTDVKKGKEMWVNASSLNMRGEPDVNGYVIARLPKGQKVSIES
STTNEETIDGISSNWYQVSSAYGNGWVFGGYLSTSEVVSYEIQPGETSFPQENPDELKTGEKRFVRSTNLRMRDEPNDYG
SVITSIPGDEKLKILDIKKEIETIAGVRSKWIYVNWNDEWEGWVFGGFVSKERGPLVDSDDISKYFQIPVDNERYVSSSF
GTRVDPVTGKIGAFHSGIDLPAPIGTPIKAVSDGKVWRTITTSGGYGVLTIISHKNNIFTYYAHQSERQVKEGDTVRSGD
IIGQVGNTGKSTGPHLHFEVRKGPDQQALDPGAYLPK

Specific function: Could be involved in cell wall degradation or formation [H]

COG id: COG0739

COG function: function code M; Membrane proteins related to metalloendopeptidases

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 LysM repeat [H]

Homologues:

Organism=Escherichia coli, GI87081989, Length=135, Percent_Identity=41.4814814814815, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI87082174, Length=118, Percent_Identity=38.135593220339, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1789099, Length=104, Percent_Identity=37.5, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR013731
- InterPro:   IPR016047
- InterPro:   IPR002886
- InterPro:   IPR018392
- InterPro:   IPR002482 [H]

Pfam domain/function: PF01476 LysM; PF08525 OapA_N; PF01551 Peptidase_M23 [H]

EC number: 3.4.24.- [C]

Molecular weight: Translated: 57445; Mature: 57445

Theoretical pI: Translated: 8.67; Mature: 8.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTLQTVFLTLILTLCNISIWSQSNLEDRDKERQSGLIKTNQKKQEEILQKYNDFVSKVQ
CCHHHHHHHHHHHHHHCCEEECCCCCCHHHHHHHCCCEECCCHHHHHHHHHHHHHHHHHH
SRFPGLKISSSPIDLKMAEGISDHNNAPGALDKKPKSITAIASDHFYLQLEPSIQPNARS
HHCCCCEECCCCCCEEECCCCCCCCCCCCCCCCCCCEEEEEECCEEEEEECCCCCCCCCC
QVKIKKGDPLEVVLVLKQDVTDKKEGSHWVLVRTKSKKEGYITQDLLQPTKPTVKSRNTE
EEEEECCCCEEEEEEEECCCCCCCCCCEEEEEEECCCCCCCEEHHHHCCCCCCHHCCCCC
GNSLDLSALPSRTTNANVTDVKKGKEMWVNASSLNMRGEPDVNGYVIARLPKGQKVSIES
CCEEEECCCCCCCCCCCCCCCCCCHHHEEEECCCCCCCCCCCCCEEEEECCCCCEEEEEC
STTNEETIDGISSNWYQVSSAYGNGWVFGGYLSTSEVVSYEIQPGETSFPQENPDELKTG
CCCCHHHHCCCCCCCEEEEECCCCCEEEEEEECCCCEEEEEECCCCCCCCCCCHHHHHCC
EKRFVRSTNLRMRDEPNDYGSVITSIPGDEKLKILDIKKEIETIAGVRSKWIYVNWNDEW
HHHHHHHCCCEECCCCCHHHHHEECCCCCCCEEEEEHHHHHHHHHCCCCEEEEEEECCCC
EGWVFGGFVSKERGPLVDSDDISKYFQIPVDNERYVSSSFGTRVDPVTGKIGAFHSGIDL
CCEEEEEEECCCCCCCCCCCCCHHEEECCCCCCCEECCCCCCCCCCCCCCCCCEECCCCC
PAPIGTPIKAVSDGKVWRTITTSGGYGVLTIISHKNNIFTYYAHQSERQVKEGDTVRSGD
CCCCCCCCEECCCCCEEEEEECCCCCEEEEEEECCCCEEEEEECCCCHHHHCCCCEECCC
IIGQVGNTGKSTGPHLHFEVRKGPDQQALDPGAYLPK
EEEECCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKTLQTVFLTLILTLCNISIWSQSNLEDRDKERQSGLIKTNQKKQEEILQKYNDFVSKVQ
CCHHHHHHHHHHHHHHCCEEECCCCCCHHHHHHHCCCEECCCHHHHHHHHHHHHHHHHHH
SRFPGLKISSSPIDLKMAEGISDHNNAPGALDKKPKSITAIASDHFYLQLEPSIQPNARS
HHCCCCEECCCCCCEEECCCCCCCCCCCCCCCCCCCEEEEEECCEEEEEECCCCCCCCCC
QVKIKKGDPLEVVLVLKQDVTDKKEGSHWVLVRTKSKKEGYITQDLLQPTKPTVKSRNTE
EEEEECCCCEEEEEEEECCCCCCCCCCEEEEEEECCCCCCCEEHHHHCCCCCCHHCCCCC
GNSLDLSALPSRTTNANVTDVKKGKEMWVNASSLNMRGEPDVNGYVIARLPKGQKVSIES
CCEEEECCCCCCCCCCCCCCCCCCHHHEEEECCCCCCCCCCCCCEEEEECCCCCEEEEEC
STTNEETIDGISSNWYQVSSAYGNGWVFGGYLSTSEVVSYEIQPGETSFPQENPDELKTG
CCCCHHHHCCCCCCCEEEEECCCCCEEEEEEECCCCEEEEEECCCCCCCCCCCHHHHHCC
EKRFVRSTNLRMRDEPNDYGSVITSIPGDEKLKILDIKKEIETIAGVRSKWIYVNWNDEW
HHHHHHHCCCEECCCCCHHHHHEECCCCCCCEEEEEHHHHHHHHHCCCCEEEEEEECCCC
EGWVFGGFVSKERGPLVDSDDISKYFQIPVDNERYVSSSFGTRVDPVTGKIGAFHSGIDL
CCEEEEEEECCCCCCCCCCCCCHHEEECCCCCCCEECCCCCCCCCCCCCCCCCEECCCCC
PAPIGTPIKAVSDGKVWRTITTSGGYGVLTIISHKNNIFTYYAHQSERQVKEGDTVRSGD
CCCCCCCCEECCCCCEEEEEECCCCCEEEEEEECCCCEEEEEECCCCHHHHCCCCEECCC
IIGQVGNTGKSTGPHLHFEVRKGPDQQALDPGAYLPK
EEEECCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]