| Definition | Leptospira biflexa serovar Patoc strain 'Patoc 1 (Paris)' chromosome chromosome I, complete sequence. |
|---|---|
| Accession | NC_010602 |
| Length | 3,599,677 |
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The map label for this gene is pbpE [H]
Identifier: 183219915
GI number: 183219915
Start: 491795
End: 493843
Strand: Reverse
Name: pbpE [H]
Synonym: LEPBI_I0497
Alternate gene names: 183219915
Gene position: 493843-491795 (Counterclockwise)
Preceding gene: 183219916
Following gene: 183219914
Centisome position: 13.72
GC content: 36.26
Gene sequence:
>2049_bases ATGACCAAATGGATATTCACCTTTCTTCTGTTCAGTTTTACTTTTCTCAACTGTTCAGAAGATGGAATTGGATCTTTCTC AGAAGAAACCAAAGAAAAAATACGTAAAAAAATCAAACAAGAAGGATTCCAAGGAGTTGTCCTGATCTCCCAAGATGATA CCGTTTTGTTTCGCGAAACGATTTCAACAGGGAAACGTAGAAAACGATCGCAACTCTTTAAAAAAAATAATTTTCCGTTG GGAGAATCTAGCAAACTATTCACAACTTTTTTAATCCATCGATTGGAGAAAGATCAAAAATTATCCCTCAAAGATCCTGT TCAAAAACATTTAAAATGGTTTCCCCATTCTAAAATCACCATTGAACATCTGTTAAGACATACATCAGGATTACCAAAAA TCATTGAATTTTTACCAAATTTGGATACGGAAGGATCCAAGTTCAACCGCGAAGATATTAAAAAATCATACTTAGAATCA AATTTAAAACCAAACTTTAGTCCGGGAGAATACTGGAAGTACAGCCGGTTGGATTATTTTTTTTTGGCTTATCTCATCGA ATCCATCACGTCAAAATCATTTCCCACTGTTGTGAAACAGGAAATTTTCGAACCTTTAGGAATGAAACATTCTCAAGTAG ACTCAAACGACATTTTATTAGGAAATAGTGGGATTCTCAGCACACCAGAAGATTTACTACTCTTTGCAGAAACAATTTCA AAAACAAAATATATTTCAAAGGAAGGAAAAGATTCAATCATCAAAAAAACAGTGTTAGCTGATGCGATAGCAGAAGATCC AATCTCTTTTGGAGAAGGGGTATATGTTGGTGATTATTTTTATTGGACATACGGGAAAAAGAAAGGAATCTCAAACTTTA TCTACCATGACCTTAAAAGTAGAATTTTGATAACCATCGTAAGTCCTTATGGTGGAAGCAAAGGAGATTTATCCTCTATC AAATCCACTTTAACCGAAATCATCTTTGAAGCAAAAAAATTAAATTTCAAAAAAAGAACTGGGTCACCAAACGAAGTATA TATTGAAGACCTAATGAAACAAGAACATGTGCCATCTCTTGGAATCGCCATTTATAAAAATTATAACTTACATTGGAAAA AAATGTATGGTACAAAAATACAACAGACTCTTTTTCGAGCGGGTTCCTTATCTAAAACGATGACAGCAACGGCAACATTA CGTTTGGTTGAAACGGGACAATTGGATTTATATTCTAACTGGATTGGAAAACTAAAACAGTACAAAGTGTCCGTTCCAAA AGGAAAAAAAAGAAGTTTGGTGAACTTAGACTTACTTTTATCTCATACCAGTGGATTAACAGAAAAAGGAAATTGGGACG ACCCTATCAATTCAGATAAAAAACACTTAAAAGACCTAAAAGATACCAATGCCACCAAAGGGAATGGTTTAAAATTGTAT TACAAACCAGGCACCAAATCTAGATACTCGGGAGGAGGATTTAGCATCGTCCAAGAGATCTTGACGGATCGTACGGGAAA ACCTTTCCCCACACTTATGGAAGAAATTGTATTCCAACCTTTACATATGAAACGTAGTACCTTCAAACAGAACCTAACGG AAGCAGATGATCGTTGTGATGGTTTTGATGAAACAGGAAAACTTTTACCTGAAAAAAAATTCGTAACACCTGAATTGTCT TCAGGAGGTCTTTGGACTACTCCAGAGGAGATTGGAACCGTTTTTAGCGAAGTGGCAAAGGCAAAACAAGGTCGTTCCCA ATTTCTCAGTAAGGAATCTGCCGAATACCTTCTGTCTCCCAAAATGAGTGCTGCCAGTTTGACCGTCCATGCCTTAGTCG CTCACGGATTCTTTTTGAATCGAACCGGAAAAACAGAATATTTCTTCCATGGAGGCCATACAAAGGGACATAAGTCTCTT GCCATCTTCAATGCGGAAAAAGGGTACGGAGTGGTCATTATGACCAATTCAGAGAATGGGTCGAAACTGATTTGGAGGAT CCTCCGGACCATTTCTGTAGATGAAAAATGGGATAAGTTTGTGAATTAA
Upstream 100 bases:
>100_bases TTGCGAACGTGGCGGCGACGATGATGGATTTGTTGGGTTTTATTGCTCCAGATGGGTACCACCCGAGTCTAATCAATAGA AATTAAATTTCTCCAGTCCT
Downstream 100 bases:
>100_bases TCTATTGACCAAATTTTTAAATTGGCTATTCTCTAAGCGATTCGATGGAATATACAGAATCTAAATCTAACGGAATTGTA GTCCTTAAATTGTTTGGCAA
Product: putative penicillin-binding protein, transpeptidase
Products: NA
Alternate protein names: PBP 4*; PBP 4A; Penicillin-binding protein E [H]
Number of amino acids: Translated: 682; Mature: 681
Protein sequence:
>682_residues MTKWIFTFLLFSFTFLNCSEDGIGSFSEETKEKIRKKIKQEGFQGVVLISQDDTVLFRETISTGKRRKRSQLFKKNNFPL GESSKLFTTFLIHRLEKDQKLSLKDPVQKHLKWFPHSKITIEHLLRHTSGLPKIIEFLPNLDTEGSKFNREDIKKSYLES NLKPNFSPGEYWKYSRLDYFFLAYLIESITSKSFPTVVKQEIFEPLGMKHSQVDSNDILLGNSGILSTPEDLLLFAETIS KTKYISKEGKDSIIKKTVLADAIAEDPISFGEGVYVGDYFYWTYGKKKGISNFIYHDLKSRILITIVSPYGGSKGDLSSI KSTLTEIIFEAKKLNFKKRTGSPNEVYIEDLMKQEHVPSLGIAIYKNYNLHWKKMYGTKIQQTLFRAGSLSKTMTATATL RLVETGQLDLYSNWIGKLKQYKVSVPKGKKRSLVNLDLLLSHTSGLTEKGNWDDPINSDKKHLKDLKDTNATKGNGLKLY YKPGTKSRYSGGGFSIVQEILTDRTGKPFPTLMEEIVFQPLHMKRSTFKQNLTEADDRCDGFDETGKLLPEKKFVTPELS SGGLWTTPEEIGTVFSEVAKAKQGRSQFLSKESAEYLLSPKMSAASLTVHALVAHGFFLNRTGKTEYFFHGGHTKGHKSL AIFNAEKGYGVVIMTNSENGSKLIWRILRTISVDEKWDKFVN
Sequences:
>Translated_682_residues MTKWIFTFLLFSFTFLNCSEDGIGSFSEETKEKIRKKIKQEGFQGVVLISQDDTVLFRETISTGKRRKRSQLFKKNNFPL GESSKLFTTFLIHRLEKDQKLSLKDPVQKHLKWFPHSKITIEHLLRHTSGLPKIIEFLPNLDTEGSKFNREDIKKSYLES NLKPNFSPGEYWKYSRLDYFFLAYLIESITSKSFPTVVKQEIFEPLGMKHSQVDSNDILLGNSGILSTPEDLLLFAETIS KTKYISKEGKDSIIKKTVLADAIAEDPISFGEGVYVGDYFYWTYGKKKGISNFIYHDLKSRILITIVSPYGGSKGDLSSI KSTLTEIIFEAKKLNFKKRTGSPNEVYIEDLMKQEHVPSLGIAIYKNYNLHWKKMYGTKIQQTLFRAGSLSKTMTATATL RLVETGQLDLYSNWIGKLKQYKVSVPKGKKRSLVNLDLLLSHTSGLTEKGNWDDPINSDKKHLKDLKDTNATKGNGLKLY YKPGTKSRYSGGGFSIVQEILTDRTGKPFPTLMEEIVFQPLHMKRSTFKQNLTEADDRCDGFDETGKLLPEKKFVTPELS SGGLWTTPEEIGTVFSEVAKAKQGRSQFLSKESAEYLLSPKMSAASLTVHALVAHGFFLNRTGKTEYFFHGGHTKGHKSL AIFNAEKGYGVVIMTNSENGSKLIWRILRTISVDEKWDKFVN >Mature_681_residues TKWIFTFLLFSFTFLNCSEDGIGSFSEETKEKIRKKIKQEGFQGVVLISQDDTVLFRETISTGKRRKRSQLFKKNNFPLG ESSKLFTTFLIHRLEKDQKLSLKDPVQKHLKWFPHSKITIEHLLRHTSGLPKIIEFLPNLDTEGSKFNREDIKKSYLESN LKPNFSPGEYWKYSRLDYFFLAYLIESITSKSFPTVVKQEIFEPLGMKHSQVDSNDILLGNSGILSTPEDLLLFAETISK TKYISKEGKDSIIKKTVLADAIAEDPISFGEGVYVGDYFYWTYGKKKGISNFIYHDLKSRILITIVSPYGGSKGDLSSIK STLTEIIFEAKKLNFKKRTGSPNEVYIEDLMKQEHVPSLGIAIYKNYNLHWKKMYGTKIQQTLFRAGSLSKTMTATATLR LVETGQLDLYSNWIGKLKQYKVSVPKGKKRSLVNLDLLLSHTSGLTEKGNWDDPINSDKKHLKDLKDTNATKGNGLKLYY KPGTKSRYSGGGFSIVQEILTDRTGKPFPTLMEEIVFQPLHMKRSTFKQNLTEADDRCDGFDETGKLLPEKKFVTPELSS GGLWTTPEEIGTVFSEVAKAKQGRSQFLSKESAEYLLSPKMSAASLTVHALVAHGFFLNRTGKTEYFFHGGHTKGHKSLA IFNAEKGYGVVIMTNSENGSKLIWRILRTISVDEKWDKFVN
Specific function: Probably involved in peptidoglycan modification during cortex synthesis [H]
COG id: COG1680
COG function: function code V; Beta-lactamase class C and other penicillin binding proteins
Gene ontology:
Cell location: Cell membrane; Peripheral membrane protein [H]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the beta-lactamase family [H]
Homologues:
Organism=Escherichia coli, GI87082101, Length=244, Percent_Identity=24.1803278688525, Blast_Score=72, Evalue=1e-13, Organism=Caenorhabditis elegans, GI115533026, Length=361, Percent_Identity=22.7146814404432, Blast_Score=67, Evalue=3e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR001466 - InterPro: IPR021860 [H]
Pfam domain/function: PF00144 Beta-lactamase; PF11954 DUF3471 [H]
EC number: NA
Molecular weight: Translated: 77536; Mature: 77405
Theoretical pI: Translated: 10.01; Mature: 10.01
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.3 %Cys (Translated Protein) 1.3 %Met (Translated Protein) 1.6 %Cys+Met (Translated Protein) 0.3 %Cys (Mature Protein) 1.2 %Met (Mature Protein) 1.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTKWIFTFLLFSFTFLNCSEDGIGSFSEETKEKIRKKIKQEGFQGVVLISQDDTVLFRET CCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCEEHHHH ISTGKRRKRSQLFKKNNFPLGESSKLFTTFLIHRLEKDQKLSLKDPVQKHLKWFPHSKIT HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHH IEHLLRHTSGLPKIIEFLPNLDTEGSKFNREDIKKSYLESNLKPNFSPGEYWKYSRLDYF HHHHHHHCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHH FLAYLIESITSKSFPTVVKQEIFEPLGMKHSQVDSNDILLGNSGILSTPEDLLLFAETIS HHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHH KTKYISKEGKDSIIKKTVLADAIAEDPISFGEGVYVGDYFYWTYGKKKGISNFIYHDLKS HHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCEEECCEEEEECCCCCCHHHHHHHHHCC RILITIVSPYGGSKGDLSSIKSTLTEIIFEAKKLNFKKRTGSPNEVYIEDLMKQEHVPSL CEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHCCCCCCHHHHHHHHHHHCCCCC GIAIYKNYNLHWKKMYGTKIQQTLFRAGSLSKTMTATATLRLVETGQLDLYSNWIGKLKQ CEEEEECCCEEEEHHHHHHHHHHHHHHCCCCHHHHHEEEEEEEECCCCHHHHHHHHHHHH YKVSVPKGKKRSLVNLDLLLSHTSGLTEKGNWDDPINSDKKHLKDLKDTNATKGNGLKLY EEECCCCCCCCCEEEHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEE YKPGTKSRYSGGGFSIVQEILTDRTGKPFPTLMEEIVFQPLHMKRSTFKQNLTEADDRCD ECCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCC GFDETGKLLPEKKFVTPELSSGGLWTTPEEIGTVFSEVAKAKQGRSQFLSKESAEYLLSP CCCHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC KMSAASLTVHALVAHGFFLNRTGKTEYFFHGGHTKGHKSLAIFNAEKGYGVVIMTNSENG CCCHHHHHHHHHHHHCCEEECCCCEEEEEECCCCCCCCEEEEEECCCCCEEEEEECCCCC SKLIWRILRTISVDEKWDKFVN HHHHHHHHHHHCCCHHHHHHCC >Mature Secondary Structure TKWIFTFLLFSFTFLNCSEDGIGSFSEETKEKIRKKIKQEGFQGVVLISQDDTVLFRET CHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCEEHHHH ISTGKRRKRSQLFKKNNFPLGESSKLFTTFLIHRLEKDQKLSLKDPVQKHLKWFPHSKIT HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHH IEHLLRHTSGLPKIIEFLPNLDTEGSKFNREDIKKSYLESNLKPNFSPGEYWKYSRLDYF HHHHHHHCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHH FLAYLIESITSKSFPTVVKQEIFEPLGMKHSQVDSNDILLGNSGILSTPEDLLLFAETIS HHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHH KTKYISKEGKDSIIKKTVLADAIAEDPISFGEGVYVGDYFYWTYGKKKGISNFIYHDLKS HHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCEEECCEEEEECCCCCCHHHHHHHHHCC RILITIVSPYGGSKGDLSSIKSTLTEIIFEAKKLNFKKRTGSPNEVYIEDLMKQEHVPSL CEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHCCCCCCHHHHHHHHHHHCCCCC GIAIYKNYNLHWKKMYGTKIQQTLFRAGSLSKTMTATATLRLVETGQLDLYSNWIGKLKQ CEEEEECCCEEEEHHHHHHHHHHHHHHCCCCHHHHHEEEEEEEECCCCHHHHHHHHHHHH YKVSVPKGKKRSLVNLDLLLSHTSGLTEKGNWDDPINSDKKHLKDLKDTNATKGNGLKLY EEECCCCCCCCCEEEHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEE YKPGTKSRYSGGGFSIVQEILTDRTGKPFPTLMEEIVFQPLHMKRSTFKQNLTEADDRCD ECCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCC GFDETGKLLPEKKFVTPELSSGGLWTTPEEIGTVFSEVAKAKQGRSQFLSKESAEYLLSP CCCHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC KMSAASLTVHALVAHGFFLNRTGKTEYFFHGGHTKGHKSLAIFNAEKGYGVVIMTNSENG CCCHHHHHHHHHHHHCCEEECCCCEEEEEECCCCCCCCEEEEEECCCCCEEEEEECCCCC SKLIWRILRTISVDEKWDKFVN HHHHHHHHHHHCCCHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 8491712; 9384377 [H]