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The map label for this gene is aacC1 [H]

Identifier: 183219632

GI number: 183219632

Start: 200974

End: 201420

Strand: Direct

Name: aacC1 [H]

Synonym: LEPBI_I0207

Alternate gene names: 183219632

Gene position: 200974-201420 (Clockwise)

Preceding gene: 183219631

Following gene: 183219634

Centisome position: 5.58

GC content: 38.03

Gene sequence:

>447_bases
ATGGAAAACGTAGAAATCAAAAAACTAACTTCCTCTGATTTGGAACAATTCCTCGAACTCATTCGGGTATTCGAAGATGT
GTTTGAGATGAAAGAGTTTCAAATGCCAAAATCAAATTACTTACAAACCCTTTTGGAACGTGATGATTTTTTTGTCTTTG
TTTCAGTTTTGGAAGGCAAGGTTGTAGCTGGACTCACCGCCTATTTATTACGACAATACTATTCAGAAAGGCCACTCGTT
TACATTTATGATTTAGCAGTACAATCGCATTTGCAAAGAAAGGGGATTGGTAAATCTCTCATTGCATCGATCAATTCCTA
TTGCAAAGAGAAAGGGATGGAAGAGGTCTTTGTCCAAGCGGATTTGGCTGACGACTATGCTTTGGATTTTTATAAAGCAA
CGGGTGGTCGGCCAGAAGATGTGGTGCATTTTTATTATCCACTTTAA

Upstream 100 bases:

>100_bases
GAGTATTGGAACGATTAAAATAATTTTAATAGGAACTCGTAATCCAATTTAATCGGAAAGGAATGTACCAAGAGAGTTAA
GAATTCGATCGAAAGGAAAC

Downstream 100 bases:

>100_bases
ATTCAATATCATTGGAAAGATTGGAGCGGATAACGCGGTCAATGTTAGTAAAAGACAAAGATCAACTAACCGATGCGAGG
CGCCCCAATGCATTTAACCG

Product: putative acetyltransferase

Products: NA

Alternate protein names: AAC(3)-I; Aminoglycoside N(3')-acetyltransferase I; Gentamicin acetyltransferase I [H]

Number of amino acids: Translated: 148; Mature: 148

Protein sequence:

>148_residues
MENVEIKKLTSSDLEQFLELIRVFEDVFEMKEFQMPKSNYLQTLLERDDFFVFVSVLEGKVVAGLTAYLLRQYYSERPLV
YIYDLAVQSHLQRKGIGKSLIASINSYCKEKGMEEVFVQADLADDYALDFYKATGGRPEDVVHFYYPL

Sequences:

>Translated_148_residues
MENVEIKKLTSSDLEQFLELIRVFEDVFEMKEFQMPKSNYLQTLLERDDFFVFVSVLEGKVVAGLTAYLLRQYYSERPLV
YIYDLAVQSHLQRKGIGKSLIASINSYCKEKGMEEVFVQADLADDYALDFYKATGGRPEDVVHFYYPL
>Mature_148_residues
MENVEIKKLTSSDLEQFLELIRVFEDVFEMKEFQMPKSNYLQTLLERDDFFVFVSVLEGKVVAGLTAYLLRQYYSERPLV
YIYDLAVQSHLQRKGIGKSLIASINSYCKEKGMEEVFVQADLADDYALDFYKATGGRPEDVVHFYYPL

Specific function: Responsible for gentamicin resistance and has a limited substrate range [H]

COG id: COG0454

COG function: function code KR; Histone acetyltransferase HPA2 and related acetyltransferases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181 [H]

Pfam domain/function: PF00583 Acetyltransf_1 [H]

EC number: =2.3.1.60 [H]

Molecular weight: Translated: 17252; Mature: 17252

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENVEIKKLTSSDLEQFLELIRVFEDVFEMKEFQMPKSNYLQTLLERDDFFVFVSVLEGK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEHHHHHHCH
VVAGLTAYLLRQYYSERPLVYIYDLAVQSHLQRKGIGKSLIASINSYCKEKGMEEVFVQA
HHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHH
DLADDYALDFYKATGGRPEDVVHFYYPL
CCCCHHHHHHHHCCCCCCCCEEEEECCC
>Mature Secondary Structure
MENVEIKKLTSSDLEQFLELIRVFEDVFEMKEFQMPKSNYLQTLLERDDFFVFVSVLEGK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEHHHHHHCH
VVAGLTAYLLRQYYSERPLVYIYDLAVQSHLQRKGIGKSLIASINSYCKEKGMEEVFVQA
HHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHH
DLADDYALDFYKATGGRPEDVVHFYYPL
CCCCHHHHHHHHCCCCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2549372 [H]