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The map label for this gene is pntAB [H]

Identifier: 183219605

GI number: 183219605

Start: 175139

End: 175429

Strand: Direct

Name: pntAB [H]

Synonym: LEPBI_I0180

Alternate gene names: 183219605

Gene position: 175139-175429 (Clockwise)

Preceding gene: 183219604

Following gene: 183219606

Centisome position: 4.87

GC content: 43.3

Gene sequence:

>291_bases
ATGGAAATATTTGTTACAGCCGTCACGATTTTCGTCCTCGCGATCTTCGTGGGATTTGAAATCATCACAAAAATCCCTCC
CATCCTCCACACCCCACTTATGTCGGGTTCCAACGCCATTTCCGGCATCACTTTGATTGGGGCACTGTATGCCGCAGGGA
TCCAAGAGAGTAATATGACCAAAATTTTAGGATTACTCTCGGTAATTTTTGCCACTATCAACGTTGTGGGTGGATTTCTT
GTCACTCATAGAATGCTTGGCATGTTTAAGAAAAAGGATGCACCAAAATAA

Upstream 100 bases:

>100_bases
GAAATTTGATTCAAAATGTAAGTTCTGGCATTAGTTTACGGAAAATTCCCTAAAATTTTGTTTCCAAAATGGCCATTTTT
TCCATAACTACTACTAGTTT

Downstream 100 bases:

>100_bases
TGGAACTCATTAGTATTTTAAATCTCGCTTACCTCATAGCATCCATCCTATTCATCGTAGGAATCAAACAACTCGCGCAT
CCTAAAACAGCAACTCGAGG

Product: NAD(P) transhydrogenase subunit alpha part 2

Products: NA

Alternate protein names: Nicotinamide nucleotide transhydrogenase subunit alpha 2; Proton-translocating transhydrogenase component 2; Pyridine nucleotide transhydrogenase subunit alpha 2; dII [H]

Number of amino acids: Translated: 96; Mature: 96

Protein sequence:

>96_residues
MEIFVTAVTIFVLAIFVGFEIITKIPPILHTPLMSGSNAISGITLIGALYAAGIQESNMTKILGLLSVIFATINVVGGFL
VTHRMLGMFKKKDAPK

Sequences:

>Translated_96_residues
MEIFVTAVTIFVLAIFVGFEIITKIPPILHTPLMSGSNAISGITLIGALYAAGIQESNMTKILGLLSVIFATINVVGGFL
VTHRMLGMFKKKDAPK
>Mature_96_residues
MEIFVTAVTIFVLAIFVGFEIITKIPPILHTPLMSGSNAISGITLIGALYAAGIQESNMTKILGLLSVIFATINVVGGFL
VTHRMLGMFKKKDAPK

Specific function: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane [H]

COG id: COG3288

COG function: function code C; NAD/NADP transhydrogenase alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI122939155, Length=94, Percent_Identity=43.6170212765958, Blast_Score=77, Evalue=4e-15,
Organism=Homo sapiens, GI122939153, Length=94, Percent_Identity=43.6170212765958, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1787887, Length=89, Percent_Identity=44.9438202247191, Blast_Score=77, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17550456, Length=89, Percent_Identity=47.1910112359551, Blast_Score=84, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: =1.6.1.2 [H]

Molecular weight: Translated: 10264; Mature: 10264

Theoretical pI: Translated: 10.29; Mature: 10.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIFVTAVTIFVLAIFVGFEIITKIPPILHTPLMSGSNAISGITLIGALYAAGIQESNMT
CHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCHHH
KILGLLSVIFATINVVGGFLVTHRMLGMFKKKDAPK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MEIFVTAVTIFVLAIFVGFEIITKIPPILHTPLMSGSNAISGITLIGALYAAGIQESNMT
CHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCHHH
KILGLLSVIFATINVVGGFLVTHRMLGMFKKKDAPK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8075801 [H]