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The map label for this gene is ychK [C]

Identifier: 183219581

GI number: 183219581

Start: 151362

End: 153113

Strand: Direct

Name: ychK [C]

Synonym: LEPBI_I0156

Alternate gene names: 183219581

Gene position: 151362-153113 (Clockwise)

Preceding gene: 183219580

Following gene: 183219585

Centisome position: 4.2

GC content: 40.47

Gene sequence:

>1752_bases
ATGAAACGCACAGAATTAGAACGACAAGCGATACAGAAATTTTTAAAGTCTGTGGAGCTTTTCAAAAAACTTCCCCCATC
GGTTCTCACTCGCTTAGCGAATAATGTCCAAGAAAAATTAATCCGTAGTCATGAAGCTCTCTATTACAAAGGGGAGTCTT
CTGAATCTATCTATATTGTTCGATATGGCGAAATTCTATTGGAAAATGTAGGTGGTCAATCTCATGTGTATGTGGGATCA
GGCCAAGTCCTTGCCGAAAATTCACTCATCTCTAGTTCCAATCATTCTACATCTGCCATTGCCGTCATTGATACACTCGT
GTATGTATTGAATGGAAAGTTGTTTTTGCAATTAGCATCCCAAGAAAAAATCTTTGCGCAAAACATCATCCAAATGATGG
GAACAAGGATGCGTGAAAATTTAGATCGTTCCAATCTGAAAGATAAAGTGATCGGTTTACGTAGGTTATGTGTTCATATT
CCGTTAGAACCTGAATACCATTTTGGAGAAAAGGTAAAAGCATTTTTAGATGAATATGGAGAAGTGACAAAAAAACTCTC
CTCGGCCATTCCGATTTCCACTTTCAAAGGGATGGACCCCACTCAAATTTCGGAGTATCTTACCAATCTTCGTAATAAAA
CACCACTCCTCCATATATACTTTGATGAATCCACATCAAGAGTCGACTTACACTACTTAGTGGTTCAGTCTGACTTTTTA
GTATTTTGGGAAGATGATCCCGAAAAATTTTACAAAGAAAAAGAAGAGATCATCCATTTTTGGAAAAGTCGCATTCGTAA
CTTCGAAGGCCGTGCAATTCGAATGATGGAAAGTGGAGTGAGGAAAAGTTACCTCCCACAAGACCAATCCTTAAAAACCT
TTTACCAAAAAGACACTCTTGCACGTTATCTTGTATCAAAAACTAGAGGACTGGCGTTAGGTGGTGGCGGTGCCAGGGCA
CTTGCACATGTGGGATTACTCAAGGTTTTACATAGAGAAGGCATTCATTTTGATTTTGTTTCTGGTGCTTCCATGGGAGC
CGTCATTGCCGCATTGTATGCAAGGAAAAATAGCCCCGAGGAAATCGAAGAAATGGTAAAAAACTTCTTCGGAGGACTCG
AAAGTGCATTTGATCCGACTTTACCTGTGGTTGCGTTTTTTAAGGGCAAACGAATGAAACGTATGTTAAAAAAAGGATTT
GGTGACCAAAGGATCGAAGAACTACCACTTCCTTTTGCCACATCTGCAGTGGATTTACAAACTGGAAAAGAACATATTTT
TGACCAAGGACCGATCACAGAAGCACTCACAAGTGCCATGAGTTTGCCCGGTGCCTTTCCTCCTTACCGCCTCGGCGAAA
AGTTGTTAGTCGATGGTGGTATGATCAATAATGTTCCCGAAAATCTCATTCGATCCAAAGGAGCCGACGTGGTGATGGGA
ATTAACGTATCACCCCTCCAAGAAATTGTGCCAGTGAAACTCTTTGAAGACCGTAATACCACAGAAAAAGGATTCTTTCG
TTACATTTGGGACACTCTCAAATACCCACCCATCCTACAAATCATGACAAGGACCATCACCTTGGAAGGAAGGGAAATCA
CACGCCTCAAACGTCCGAAGATGGATTTGTTTGTACATTTTCATTTGGAAGAGTTTCAGTTATTTGATTTTGCGAGATAC
CAAGAGATCATTGATAAAGGGGAAAGAGAAGCTGAGGCGAACTTAGCTGAGATCAAACAATTGTTTTCGTAA

Upstream 100 bases:

>100_bases
TGCGTTTTTTATTTGGATTTTACTCTTGGCAGTGCTTTTTGTCGGAAAATTTCGTAGGAAGGAGTGGGTGAACATACGAA
TTTAATAAGGTGAGGGAAGA

Downstream 100 bases:

>100_bases
ACTTGGATTTCCAATCCCATCGAACGAAAACCATGTGGAATGTTCGATAGGATTGAAAACAGTATCTGGAAGAATTTTAT
CTCCTTACATCGAAGAAAGG

Product: putative cAMP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 583; Mature: 583

Protein sequence:

>583_residues
MKRTELERQAIQKFLKSVELFKKLPPSVLTRLANNVQEKLIRSHEALYYKGESSESIYIVRYGEILLENVGGQSHVYVGS
GQVLAENSLISSSNHSTSAIAVIDTLVYVLNGKLFLQLASQEKIFAQNIIQMMGTRMRENLDRSNLKDKVIGLRRLCVHI
PLEPEYHFGEKVKAFLDEYGEVTKKLSSAIPISTFKGMDPTQISEYLTNLRNKTPLLHIYFDESTSRVDLHYLVVQSDFL
VFWEDDPEKFYKEKEEIIHFWKSRIRNFEGRAIRMMESGVRKSYLPQDQSLKTFYQKDTLARYLVSKTRGLALGGGGARA
LAHVGLLKVLHREGIHFDFVSGASMGAVIAALYARKNSPEEIEEMVKNFFGGLESAFDPTLPVVAFFKGKRMKRMLKKGF
GDQRIEELPLPFATSAVDLQTGKEHIFDQGPITEALTSAMSLPGAFPPYRLGEKLLVDGGMINNVPENLIRSKGADVVMG
INVSPLQEIVPVKLFEDRNTTEKGFFRYIWDTLKYPPILQIMTRTITLEGREITRLKRPKMDLFVHFHLEEFQLFDFARY
QEIIDKGEREAEANLAEIKQLFS

Sequences:

>Translated_583_residues
MKRTELERQAIQKFLKSVELFKKLPPSVLTRLANNVQEKLIRSHEALYYKGESSESIYIVRYGEILLENVGGQSHVYVGS
GQVLAENSLISSSNHSTSAIAVIDTLVYVLNGKLFLQLASQEKIFAQNIIQMMGTRMRENLDRSNLKDKVIGLRRLCVHI
PLEPEYHFGEKVKAFLDEYGEVTKKLSSAIPISTFKGMDPTQISEYLTNLRNKTPLLHIYFDESTSRVDLHYLVVQSDFL
VFWEDDPEKFYKEKEEIIHFWKSRIRNFEGRAIRMMESGVRKSYLPQDQSLKTFYQKDTLARYLVSKTRGLALGGGGARA
LAHVGLLKVLHREGIHFDFVSGASMGAVIAALYARKNSPEEIEEMVKNFFGGLESAFDPTLPVVAFFKGKRMKRMLKKGF
GDQRIEELPLPFATSAVDLQTGKEHIFDQGPITEALTSAMSLPGAFPPYRLGEKLLVDGGMINNVPENLIRSKGADVVMG
INVSPLQEIVPVKLFEDRNTTEKGFFRYIWDTLKYPPILQIMTRTITLEGREITRLKRPKMDLFVHFHLEEFQLFDFARY
QEIIDKGEREAEANLAEIKQLFS
>Mature_583_residues
MKRTELERQAIQKFLKSVELFKKLPPSVLTRLANNVQEKLIRSHEALYYKGESSESIYIVRYGEILLENVGGQSHVYVGS
GQVLAENSLISSSNHSTSAIAVIDTLVYVLNGKLFLQLASQEKIFAQNIIQMMGTRMRENLDRSNLKDKVIGLRRLCVHI
PLEPEYHFGEKVKAFLDEYGEVTKKLSSAIPISTFKGMDPTQISEYLTNLRNKTPLLHIYFDESTSRVDLHYLVVQSDFL
VFWEDDPEKFYKEKEEIIHFWKSRIRNFEGRAIRMMESGVRKSYLPQDQSLKTFYQKDTLARYLVSKTRGLALGGGGARA
LAHVGLLKVLHREGIHFDFVSGASMGAVIAALYARKNSPEEIEEMVKNFFGGLESAFDPTLPVVAFFKGKRMKRMLKKGF
GDQRIEELPLPFATSAVDLQTGKEHIFDQGPITEALTSAMSLPGAFPPYRLGEKLLVDGGMINNVPENLIRSKGADVVMG
INVSPLQEIVPVKLFEDRNTTEKGFFRYIWDTLKYPPILQIMTRTITLEGREITRLKRPKMDLFVHFHLEEFQLFDFARY
QEIIDKGEREAEANLAEIKQLFS

Specific function: Unknown

COG id: COG1752

COG function: function code R; Predicted esterase of the alpha-beta hydrolase superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 patatin domain [H]

Homologues:

Organism=Homo sapiens, GI260656037, Length=284, Percent_Identity=30.9859154929577, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI260656039, Length=284, Percent_Identity=30.9859154929577, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI260656041, Length=284, Percent_Identity=30.9859154929577, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI116256487, Length=284, Percent_Identity=30.9859154929577, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI260656043, Length=284, Percent_Identity=30.9859154929577, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI148727335, Length=281, Percent_Identity=30.2491103202847, Blast_Score=122, Evalue=1e-27,
Organism=Homo sapiens, GI148727290, Length=281, Percent_Identity=30.2491103202847, Blast_Score=122, Evalue=1e-27,
Organism=Escherichia coli, GI226510936, Length=302, Percent_Identity=26.8211920529801, Blast_Score=107, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI71997299, Length=259, Percent_Identity=28.1853281853282, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71997289, Length=259, Percent_Identity=28.1853281853282, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI193204778, Length=298, Percent_Identity=28.5234899328859, Blast_Score=88, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6323581, Length=315, Percent_Identity=27.3015873015873, Blast_Score=134, Evalue=4e-32,
Organism=Drosophila melanogaster, GI281376913, Length=280, Percent_Identity=28.5714285714286, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI28571388, Length=279, Percent_Identity=27.9569892473118, Blast_Score=109, Evalue=5e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016035
- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001423
- InterPro:   IPR002641
- InterPro:   IPR014710 [H]

Pfam domain/function: PF00027 cNMP_binding; PF01734 Patatin [H]

EC number: NA

Molecular weight: Translated: 66540; Mature: 66540

Theoretical pI: Translated: 9.07; Mature: 9.07

Prosite motif: PS50042 CNMP_BINDING_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRTELERQAIQKFLKSVELFKKLPPSVLTRLANNVQEKLIRSHEALYYKGESSESIYIV
CCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEEE
RYGEILLENVGGQSHVYVGSGQVLAENSLISSSNHSTSAIAVIDTLVYVLNGKLFLQLAS
EEHHHHHHHCCCCCEEEECCCCEEECCCEECCCCCCCHHHHHHHHHHHHHCCCEEEEECC
QEKIFAQNIIQMMGTRMRENLDRSNLKDKVIGLRRLCVHIPLEPEYHFGEKVKAFLDEYG
CHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHH
EVTKKLSSAIPISTFKGMDPTQISEYLTNLRNKTPLLHIYFDESTSRVDLHYLVVQSDFL
HHHHHHHHCCCCHHCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEEEEEECCEE
VFWEDDPEKFYKEKEEIIHFWKSRIRNFEGRAIRMMESGVRKSYLPQDQSLKTFYQKDTL
EEECCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
ARYLVSKTRGLALGGGGARALAHVGLLKVLHREGIHFDFVSGASMGAVIAALYARKNSPE
HHHHHHHHCCEEECCCHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHCCCCHH
EIEEMVKNFFGGLESAFDPTLPVVAFFKGKRMKRMLKKGFGDQRIEELPLPFATSAVDLQ
HHHHHHHHHHCCHHHHCCCCCHHHHHHCCHHHHHHHHCCCCHHHHHHCCCCCCCCCEEHH
TGKEHIFDQGPITEALTSAMSLPGAFPPYRLGEKLLVDGGMINNVPENLIRSKGADVVMG
CCHHHHCCCCCHHHHHHHHHHCCCCCCCHHCCCCEEECCCCCCHHHHHHHHCCCCCEEEE
INVSPLQEIVPVKLFEDRNTTEKGFFRYIWDTLKYPPILQIMTRTITLEGREITRLKRPK
CCCCCHHHHCCHHEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHEECCCHHHHHCCCC
MDLFVHFHLEEFQLFDFARYQEIIDKGEREAEANLAEIKQLFS
EEEEEEEEHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHC
>Mature Secondary Structure
MKRTELERQAIQKFLKSVELFKKLPPSVLTRLANNVQEKLIRSHEALYYKGESSESIYIV
CCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEEE
RYGEILLENVGGQSHVYVGSGQVLAENSLISSSNHSTSAIAVIDTLVYVLNGKLFLQLAS
EEHHHHHHHCCCCCEEEECCCCEEECCCEECCCCCCCHHHHHHHHHHHHHCCCEEEEECC
QEKIFAQNIIQMMGTRMRENLDRSNLKDKVIGLRRLCVHIPLEPEYHFGEKVKAFLDEYG
CHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHH
EVTKKLSSAIPISTFKGMDPTQISEYLTNLRNKTPLLHIYFDESTSRVDLHYLVVQSDFL
HHHHHHHHCCCCHHCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEEEEEECCEE
VFWEDDPEKFYKEKEEIIHFWKSRIRNFEGRAIRMMESGVRKSYLPQDQSLKTFYQKDTL
EEECCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
ARYLVSKTRGLALGGGGARALAHVGLLKVLHREGIHFDFVSGASMGAVIAALYARKNSPE
HHHHHHHHCCEEECCCHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHCCCCHH
EIEEMVKNFFGGLESAFDPTLPVVAFFKGKRMKRMLKKGFGDQRIEELPLPFATSAVDLQ
HHHHHHHHHHCCHHHHCCCCCHHHHHHCCHHHHHHHHCCCCHHHHHHCCCCCCCCCEEHH
TGKEHIFDQGPITEALTSAMSLPGAFPPYRLGEKLLVDGGMINNVPENLIRSKGADVVMG
CCHHHHCCCCCHHHHHHHHHHCCCCCCCHHCCCCEEECCCCCCHHHHHHHHCCCCCEEEE
INVSPLQEIVPVKLFEDRNTTEKGFFRYIWDTLKYPPILQIMTRTITLEGREITRLKRPK
CCCCCHHHHCCHHEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHEECCCHHHHHCCCC
MDLFVHFHLEEFQLFDFARYQEIIDKGEREAEANLAEIKQLFS
EEEEEEEEHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]