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The map label for this gene is coaD

Identifier: 183219513

GI number: 183219513

Start: 86381

End: 86863

Strand: Reverse

Name: coaD

Synonym: LEPBI_I0086

Alternate gene names: 183219513

Gene position: 86863-86381 (Counterclockwise)

Preceding gene: 183219514

Following gene: 183219512

Centisome position: 2.41

GC content: 40.37

Gene sequence:

>483_bases
ATGAAAAGTATCGCCGTATACCCTGGTTCCTTTGATCCATTCACCAATGGACATTTAGATATCATACGGCGAGCCCATCC
ACTGTTTGAAGAAATCATCATTGCAGTTGCGATCAATTCAAAGAAAACCTCACTTTTCTCTCCTGAAGAACGAGTGGAGA
TGATTGGAAAGGTGTTCCACGGATGGGACAAAATCAAAATTGATACGTTTGAAGGCCTTACGGTTGATTACTGTAAGGAA
AAAAATTCGCGAGTCATTCTCAGAGGCCTACGTGCTGTGACCGATTTTGATTATGAATATGCAATTTCCTTGATGAACAA
AAAATTAGCCCCAGAAATTGAAACTTATTTCTTAATGGCAGACAATGAGTACTCTTTTGTGTCTTCCACTATCGTCAAAG
AAGTAGCAAGGCATGGTAGAGCTGTATCCAATCAAGTCCCTGATGTTGTAGGGGAAGCCCTTGTGAAAAAATTCTCCGTT
TGA

Upstream 100 bases:

>100_bases
ACATTTGAAAAAGAAGAATTGTACAACCAGTACGATGCAGAAGGTTTCATCAATTTGTATGGCCTTCCAATGAAAGAATG
GGCAAGGGTAAACCAATAAG

Downstream 100 bases:

>100_bases
TCGGACTTTGAGGATCTATGAAAACTCGTTCTACTGTTTTTTACGGTTTTACACTATTATTGTTTGGATCCTTAGGATAT
TACTTACTCCAAGCAGGTGG

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 160; Mature: 160

Protein sequence:

>160_residues
MKSIAVYPGSFDPFTNGHLDIIRRAHPLFEEIIIAVAINSKKTSLFSPEERVEMIGKVFHGWDKIKIDTFEGLTVDYCKE
KNSRVILRGLRAVTDFDYEYAISLMNKKLAPEIETYFLMADNEYSFVSSTIVKEVARHGRAVSNQVPDVVGEALVKKFSV

Sequences:

>Translated_160_residues
MKSIAVYPGSFDPFTNGHLDIIRRAHPLFEEIIIAVAINSKKTSLFSPEERVEMIGKVFHGWDKIKIDTFEGLTVDYCKE
KNSRVILRGLRAVTDFDYEYAISLMNKKLAPEIETYFLMADNEYSFVSSTIVKEVARHGRAVSNQVPDVVGEALVKKFSV
>Mature_160_residues
MKSIAVYPGSFDPFTNGHLDIIRRAHPLFEEIIIAVAINSKKTSLFSPEERVEMIGKVFHGWDKIKIDTFEGLTVDYCKE
KNSRVILRGLRAVTDFDYEYAISLMNKKLAPEIETYFLMADNEYSFVSSTIVKEVARHGRAVSNQVPDVVGEALVKKFSV

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=159, Percent_Identity=41.5094339622642, Blast_Score=149, Evalue=6e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_LEPBA (B0S9J5)

Other databases:

- EMBL:   CP000777
- RefSeq:   YP_001961210.1
- ProteinModelPortal:   B0S9J5
- SMR:   B0S9J5
- GeneID:   6389151
- GenomeReviews:   CP000777_GR
- KEGG:   lbf:LBF_0086
- HOGENOM:   HBG288308
- OMA:   VRQIAAM
- ProtClustDB:   PRK00168
- BioCyc:   LBIF355278:LBF_0086-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 18150; Mature: 18150

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSIAVYPGSFDPFTNGHLDIIRRAHPLFEEIIIAVAINSKKTSLFSPEERVEMIGKVFH
CCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCHHHHHHHHHHHC
GWDKIKIDTFEGLTVDYCKEKNSRVILRGLRAVTDFDYEYAISLMNKKLAPEIETYFLMA
CCCEEEEECCCCCCHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEEE
DNEYSFVSSTIVKEVARHGRAVSNQVPDVVGEALVKKFSV
CCCHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MKSIAVYPGSFDPFTNGHLDIIRRAHPLFEEIIIAVAINSKKTSLFSPEERVEMIGKVFH
CCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCHHHHHHHHHHHC
GWDKIKIDTFEGLTVDYCKEKNSRVILRGLRAVTDFDYEYAISLMNKKLAPEIETYFLMA
CCCEEEEECCCCCCHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEEE
DNEYSFVSSTIVKEVARHGRAVSNQVPDVVGEALVKKFSV
CCCHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA