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The map label for this gene is gntK [H]

Identifier: 182677618

GI number: 182677618

Start: 705799

End: 706299

Strand: Direct

Name: gntK [H]

Synonym: Bind_0625

Alternate gene names: 182677618

Gene position: 705799-706299 (Clockwise)

Preceding gene: 182677612

Following gene: 182677619

Centisome position: 16.93

GC content: 54.49

Gene sequence:

>501_bases
ATGGTGGTCATGGGTGTATCTGGTTGCGGCAAATCGAGTATCGCCCAAAGCCTTGCCGCGAAGCTCGGTTGGGAAATGGT
CGAAGGTGACCAGTTGCATCCACCAGCGAATATCGCGCGTATGAGTGCGGGGATCCCACTTGAAGATGCGGACCGGCTAC
CTTGGCTCGACGCTATTGCGGGCGTGGTCGAGGATTGGCGTATCCAAGGGCGCCCTGGCGTTGTGACCTGTTCGTCGCTC
AAGAAACATTATCGTGAAAGGCTTACCGGACGGATAAAAGATGTCTGTTTCGTTTATCTCGCCGGTACGGAAGAGCAGAT
CATGCCGCGCCTCTCGATGCGCACTGGCCATTTCATGCCGACGACGCTTTTACGAAGTCAATTCGACGCCTTGGAAGAGC
CGGGGGAAGACGAAATAGCTCTCTATGTCTCTCTTGAGGCTTCGGTAGAAGAGATTGTTTCGGCGGTTATTAGGGTGCTC
AAGCCGCTTCTTGCAAGTTGA

Upstream 100 bases:

>100_bases
TGAGGATGCGCCTCACAAATCGGCTTTTCGCGGTCCCGAACAGGACGGTCTCATCGTCAGGCCGACCAGCGCCTTAACTC
AAGCTCGTGCTCTATCCGGG

Downstream 100 bases:

>100_bases
TGCAGACAGAACGGAAGGCTGCTTCCGCTTACCTTCGGAACTTGGGAAAAATATCCCGGCGTGATTGCGCTATTTGTTCG
AAGAGTGAGAAGAAAGCAGT

Product: carbohydrate kinase

Products: NA

Alternate protein names: Gluconate kinase 2 [H]

Number of amino acids: Translated: 166; Mature: 166

Protein sequence:

>166_residues
MVVMGVSGCGKSSIAQSLAAKLGWEMVEGDQLHPPANIARMSAGIPLEDADRLPWLDAIAGVVEDWRIQGRPGVVTCSSL
KKHYRERLTGRIKDVCFVYLAGTEEQIMPRLSMRTGHFMPTTLLRSQFDALEEPGEDEIALYVSLEASVEEIVSAVIRVL
KPLLAS

Sequences:

>Translated_166_residues
MVVMGVSGCGKSSIAQSLAAKLGWEMVEGDQLHPPANIARMSAGIPLEDADRLPWLDAIAGVVEDWRIQGRPGVVTCSSL
KKHYRERLTGRIKDVCFVYLAGTEEQIMPRLSMRTGHFMPTTLLRSQFDALEEPGEDEIALYVSLEASVEEIVSAVIRVL
KPLLAS
>Mature_166_residues
MVVMGVSGCGKSSIAQSLAAKLGWEMVEGDQLHPPANIARMSAGIPLEDADRLPWLDAIAGVVEDWRIQGRPGVVTCSSL
KKHYRERLTGRIKDVCFVYLAGTEEQIMPRLSMRTGHFMPTTLLRSQFDALEEPGEDEIALYVSLEASVEEIVSAVIRVL
KPLLAS

Specific function: Gluconate utilization system GNT-I. [C]

COG id: COG3265

COG function: function code G; Gluconate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gluconokinase gntK/gntV family [H]

Homologues:

Organism=Homo sapiens, GI299758445, Length=179, Percent_Identity=38.5474860335196, Blast_Score=125, Evalue=2e-29,
Organism=Escherichia coli, GI87082265, Length=161, Percent_Identity=41.6149068322981, Blast_Score=134, Evalue=2e-33,
Organism=Escherichia coli, GI1790719, Length=138, Percent_Identity=47.1014492753623, Blast_Score=134, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI25146487, Length=168, Percent_Identity=38.6904761904762, Blast_Score=122, Evalue=9e-29,
Organism=Saccharomyces cerevisiae, GI6320454, Length=145, Percent_Identity=39.3103448275862, Blast_Score=103, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR006001 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.12 [H]

Molecular weight: Translated: 18193; Mature: 18193

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVMGVSGCGKSSIAQSLAAKLGWEMVEGDQLHPPANIARMSAGIPLEDADRLPWLDAIA
CEEEECCCCCHHHHHHHHHHHHCCHHCCCCCCCCCHHHHHHHCCCCCCCCCCCCHHHHHH
GVVEDWRIQGRPGVVTCSSLKKHYRERLTGRIKDVCFVYLAGTEEQIMPRLSMRTGHFMP
HHHHHHEECCCCCEEEHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHCCCCCCH
TTLLRSQFDALEEPGEDEIALYVSLEASVEEIVSAVIRVLKPLLAS
HHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVVMGVSGCGKSSIAQSLAAKLGWEMVEGDQLHPPANIARMSAGIPLEDADRLPWLDAIA
CEEEECCCCCHHHHHHHHHHHHCCHHCCCCCCCCCHHHHHHHCCCCCCCCCCCCHHHHHH
GVVEDWRIQGRPGVVTCSSLKKHYRERLTGRIKDVCFVYLAGTEEQIMPRLSMRTGHFMP
HHHHHHEECCCCCEEEHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHCCCCCCH
TTLLRSQFDALEEPGEDEIALYVSLEASVEEIVSAVIRVLKPLLAS
HHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9135111; 9278503; 8655507; 11468405 [H]