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The map label for this gene is lhr [C]

Identifier: 182677369

GI number: 182677369

Start: 428599

End: 431142

Strand: Direct

Name: lhr [C]

Synonym: Bind_0372

Alternate gene names: 182677369

Gene position: 428599-431142 (Clockwise)

Preceding gene: 182677368

Following gene: 182677370

Centisome position: 10.28

GC content: 59.51

Gene sequence:

>2544_bases
ATGAAGCGCGGGCTCATTCAGAAAGAGCCGTTGCCGCCGCGTTTTGCCGCCTGGTTCGCGGCGCGCGGCTGGAGCCCGCG
GGCACATCAGCAGCATCTTCTGGCTTTGGCGCAACAGCAGGAAAATGCGCTTCTGATCGCGCCGACGGGGGCCGGCAAAA
CGCTCGCGGGTTTCCTGCCCTCCCTCGTCGATCTGGAACAAAAGCGCAATCGTGATGGGCTGCATACTCTTTATATTTCG
CCTCTGAAGGCGCTTGCGGTCGATGTTGAACGCAATCTGCAAATGCCGATTGCCGAAATGGGCCTCAAGATTACGGTTGA
GACACGCACGGGCGATACATCCACCGCCAAGCGTCTGCGTCAGCGTCGTCAGCCACCGGATATGCTGTTGACGACGCCGG
AACAACTGACGTTGCTGCTCGCCACAGCCGATGCCGAACATCTCTTCGCCGATGTGCGACGCGTTATTTTCGATGAATTG
CATGCGATCGCGCCCTCGAAACGAGGCGATCTTCTGAGCCTCGGCCTCGCGCGGCTACGTACGCTCGCGCCCATGATGCG
GACCACGGGCCTTTCGGCGACCGTGCGCGCGCCGGAGGATTTGCAACGCTGGCTCGTCTCGCAACAAGATGCAAATGCCC
TCGCCACATTGATCACGGCGCCCCCCGGCGCTCCCGCCGATTTACGCATTCTTGACAGTGACAATGCTTTGCCTTGGGCT
GGCCATAGCGCCGCCCATGCGCTGCGTGAGATTTATGCCGCGATCGAGGCCGCGACCATGACGTTGGTTTTCGTCAATAC
GCGCGCCCAGGCGGAATATGTGTTTCAGGAACTCTGGCGCATTAATGAGAAATCCTTGCCGATTGCCTTGCATCATGGCT
CGCTTGATGCCGGCCAAAGGCGCAAGGTCGAAGCGGCAATGGTACAAAACCGGCTCAAGGCGGTGGTCTGTACGTCAACG
CTCGATCTTGGCATCGATTGGGGGGCCGTCGATCTCGTGATCAATGTCGGCGCGCCCAAGGGCGCGAGCCGGCTCGCGCA
AAGGATTGGCCGGGCGAACCATCGCCTGGATGAACCGTCCCGCGCCCTTCTCGTGCCGGCCAATCGCTTCGAAGTGCTCG
AATGTCATGCCGCCGTGGAAGCGGCGCGCGCCGGCACGCAGGATACGGCTGCTGCACGCGCTGGCGCGCTCGATGTTTTG
TGTCAGCATTTGCTCGGCATGGCTTGTGTCGGTCCTTTCGATCCGCAAAGGCTTTATGAAGAAGTGATCACGGCCGCGCC
CTATGCGGGCTTAAGCCGAAAGGATTTCGACGCGGCTCTGAATTTTGCGGCCCATGGTGGCTATGCGTTGAAGGCTTATG
AACGGTTCGCTAAGCTCAAGCCCATGCCAGACGGGCGCTGGCGCATAGCCAATGGCCGTGTGGCACAGGCCTATCGCATG
AATTGTGGGACAATTGTCGAGGCCGACATGCTCAGGGTCCGCCTTGTGCCGGGCTCGGAGGGGGGACGGCGAAAAAGCGG
TCAGCCGCTCAAGACGGCTTATACGGGCCCATTGCGGCGCGGTGGCCGAATACTCGGCGAGATCGAGGACTATTTTATCG
AGACTTTGCGGCCAAAGGATACATTTCTTTTCGGCGGCGAGATTCTGGCACTCCAAGGGATTGCGGGCGATGAAGCCTTG
GTGGTGCGCAGTCACGCCGAGACGCCGAAAATTCCGTCTTATGCCGGTGGCAAGTTTCCGCTCTCGACCTATCTTGCCAA
ACGCGTACGCGAATTGCTCTCGACTCCCGAGGAATGGAACCAATTGCCACCGCAGGTCGTCGAATGGTTGGCGCTGCAGA
AACATGTTTCCCGTCTGCCACCCCCTGAGGCTTTGCTTGTCGAAACTTTCGCGCGGGGTGGTCATTTTCATCTCGTTGCC
TATCCTTTTGAGGGCCGTCTCGCGCATCAGACGCTTGGCATGTTGTTGACACGAAGAATGGAACGGGCCGGTCTGCAACC
ACTCGGCTTCGTCGCCAATGATTATGCTCTGTGTGTTTGGTCGCGCGCCGATGTCGGCGCCTGGTGCGAGGACAATAAAT
ATGCGCTGAATGCGCTTTTCGCGAAGGATATGCTGGGCGATGATCTCGAGGAATGGCTGCATGAATCGGCTCTGATGAAA
CGCACATTCCGTAATTGCGCGATCATCGCCGGATTGATCGAGCGGAATTTCCCGGGCAAACAGAAAGCTGGGCGGCAAGA
GTCGCGGCGAGTGACCATTTCGACCGATCTCATCTATGATGTCTTGCGACGGCACGAACCTGACCATGTGCTGTTGCGAG
CGGCCCGTGCCGATGCGGCGACCGGCCTTCTTGATCTCGAACGATTGGGGCTAATGCTGGCGCGTGTGCGGCATAAAATC
ATCCATCAGCCCTTGACGCATATTTCGCCGCTCGCCGTGCCGATCATGCTCGAAATCGGCCGTGAAAGGGTCTATGGCGA
GGCCCAGGATGCGCTTTTGGCCGAAGCCGCGGCGGATCTGGCGGCGGAAGCGATGGCGCCCTGA

Upstream 100 bases:

>100_bases
CGACAAGAGTTTCGCCCTGGCTGATATGGCTCAATCGTTCCTGTATGAGGAATCCGGCCAGCACTTTGGCAAGATTGTTT
TGGAGTTTTAGCCTCCTTTG

Downstream 100 bases:

>100_bases
CCTCTTGCCGCGCGAATAATTTCAGGGCGAATAATTTCAGGGATTGTGATTGTGCTGTAAAGCTTTGTCCGTGAGCCAGA
ATCCTGCCAGAACGACCACG

Product: DEAD/DEAH box helicase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 847; Mature: 847

Protein sequence:

>847_residues
MKRGLIQKEPLPPRFAAWFAARGWSPRAHQQHLLALAQQQENALLIAPTGAGKTLAGFLPSLVDLEQKRNRDGLHTLYIS
PLKALAVDVERNLQMPIAEMGLKITVETRTGDTSTAKRLRQRRQPPDMLLTTPEQLTLLLATADAEHLFADVRRVIFDEL
HAIAPSKRGDLLSLGLARLRTLAPMMRTTGLSATVRAPEDLQRWLVSQQDANALATLITAPPGAPADLRILDSDNALPWA
GHSAAHALREIYAAIEAATMTLVFVNTRAQAEYVFQELWRINEKSLPIALHHGSLDAGQRRKVEAAMVQNRLKAVVCTST
LDLGIDWGAVDLVINVGAPKGASRLAQRIGRANHRLDEPSRALLVPANRFEVLECHAAVEAARAGTQDTAAARAGALDVL
CQHLLGMACVGPFDPQRLYEEVITAAPYAGLSRKDFDAALNFAAHGGYALKAYERFAKLKPMPDGRWRIANGRVAQAYRM
NCGTIVEADMLRVRLVPGSEGGRRKSGQPLKTAYTGPLRRGGRILGEIEDYFIETLRPKDTFLFGGEILALQGIAGDEAL
VVRSHAETPKIPSYAGGKFPLSTYLAKRVRELLSTPEEWNQLPPQVVEWLALQKHVSRLPPPEALLVETFARGGHFHLVA
YPFEGRLAHQTLGMLLTRRMERAGLQPLGFVANDYALCVWSRADVGAWCEDNKYALNALFAKDMLGDDLEEWLHESALMK
RTFRNCAIIAGLIERNFPGKQKAGRQESRRVTISTDLIYDVLRRHEPDHVLLRAARADAATGLLDLERLGLMLARVRHKI
IHQPLTHISPLAVPIMLEIGRERVYGEAQDALLAEAAADLAAEAMAP

Sequences:

>Translated_847_residues
MKRGLIQKEPLPPRFAAWFAARGWSPRAHQQHLLALAQQQENALLIAPTGAGKTLAGFLPSLVDLEQKRNRDGLHTLYIS
PLKALAVDVERNLQMPIAEMGLKITVETRTGDTSTAKRLRQRRQPPDMLLTTPEQLTLLLATADAEHLFADVRRVIFDEL
HAIAPSKRGDLLSLGLARLRTLAPMMRTTGLSATVRAPEDLQRWLVSQQDANALATLITAPPGAPADLRILDSDNALPWA
GHSAAHALREIYAAIEAATMTLVFVNTRAQAEYVFQELWRINEKSLPIALHHGSLDAGQRRKVEAAMVQNRLKAVVCTST
LDLGIDWGAVDLVINVGAPKGASRLAQRIGRANHRLDEPSRALLVPANRFEVLECHAAVEAARAGTQDTAAARAGALDVL
CQHLLGMACVGPFDPQRLYEEVITAAPYAGLSRKDFDAALNFAAHGGYALKAYERFAKLKPMPDGRWRIANGRVAQAYRM
NCGTIVEADMLRVRLVPGSEGGRRKSGQPLKTAYTGPLRRGGRILGEIEDYFIETLRPKDTFLFGGEILALQGIAGDEAL
VVRSHAETPKIPSYAGGKFPLSTYLAKRVRELLSTPEEWNQLPPQVVEWLALQKHVSRLPPPEALLVETFARGGHFHLVA
YPFEGRLAHQTLGMLLTRRMERAGLQPLGFVANDYALCVWSRADVGAWCEDNKYALNALFAKDMLGDDLEEWLHESALMK
RTFRNCAIIAGLIERNFPGKQKAGRQESRRVTISTDLIYDVLRRHEPDHVLLRAARADAATGLLDLERLGLMLARVRHKI
IHQPLTHISPLAVPIMLEIGRERVYGEAQDALLAEAAADLAAEAMAP
>Mature_847_residues
MKRGLIQKEPLPPRFAAWFAARGWSPRAHQQHLLALAQQQENALLIAPTGAGKTLAGFLPSLVDLEQKRNRDGLHTLYIS
PLKALAVDVERNLQMPIAEMGLKITVETRTGDTSTAKRLRQRRQPPDMLLTTPEQLTLLLATADAEHLFADVRRVIFDEL
HAIAPSKRGDLLSLGLARLRTLAPMMRTTGLSATVRAPEDLQRWLVSQQDANALATLITAPPGAPADLRILDSDNALPWA
GHSAAHALREIYAAIEAATMTLVFVNTRAQAEYVFQELWRINEKSLPIALHHGSLDAGQRRKVEAAMVQNRLKAVVCTST
LDLGIDWGAVDLVINVGAPKGASRLAQRIGRANHRLDEPSRALLVPANRFEVLECHAAVEAARAGTQDTAAARAGALDVL
CQHLLGMACVGPFDPQRLYEEVITAAPYAGLSRKDFDAALNFAAHGGYALKAYERFAKLKPMPDGRWRIANGRVAQAYRM
NCGTIVEADMLRVRLVPGSEGGRRKSGQPLKTAYTGPLRRGGRILGEIEDYFIETLRPKDTFLFGGEILALQGIAGDEAL
VVRSHAETPKIPSYAGGKFPLSTYLAKRVRELLSTPEEWNQLPPQVVEWLALQKHVSRLPPPEALLVETFARGGHFHLVA
YPFEGRLAHQTLGMLLTRRMERAGLQPLGFVANDYALCVWSRADVGAWCEDNKYALNALFAKDMLGDDLEEWLHESALMK
RTFRNCAIIAGLIERNFPGKQKAGRQESRRVTISTDLIYDVLRRHEPDHVLLRAARADAATGLLDLERLGLMLARVRHKI
IHQPLTHISPLAVPIMLEIGRERVYGEAQDALLAEAAADLAAEAMAP

Specific function: Unknown

COG id: COG1201

COG function: function code R; Lhr-like helicases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI38569503, Length=310, Percent_Identity=28.0645161290323, Blast_Score=78, Evalue=4e-14,
Organism=Homo sapiens, GI38569505, Length=311, Percent_Identity=28.2958199356913, Blast_Score=78, Evalue=4e-14,
Organism=Escherichia coli, GI1787942, Length=912, Percent_Identity=28.2894736842105, Blast_Score=237, Evalue=2e-63,
Organism=Caenorhabditis elegans, GI17537519, Length=179, Percent_Identity=32.4022346368715, Blast_Score=74, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6320497, Length=363, Percent_Identity=27.8236914600551, Blast_Score=91, Evalue=7e-19,
Organism=Saccharomyces cerevisiae, GI9755332, Length=384, Percent_Identity=25.5208333333333, Blast_Score=87, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6321020, Length=366, Percent_Identity=24.3169398907104, Blast_Score=68, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24647182, Length=345, Percent_Identity=25.5072463768116, Blast_Score=70, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR013701
- InterPro:   IPR011545
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR017170 [H]

Pfam domain/function: PF00270 DEAD; PF08494 DEAD_assoc; PF00271 Helicase_C [H]

EC number: 3.6.1.-

Molecular weight: Translated: 93316; Mature: 93316

Theoretical pI: Translated: 9.19; Mature: 9.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRGLIQKEPLPPRFAAWFAARGWSPRAHQQHLLALAQQQENALLIAPTGAGKTLAGFLP
CCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHH
SLVDLEQKRNRDGLHTLYISPLKALAVDVERNLQMPIAEMGLKITVETRTGDTSTAKRLR
HHHHHHHHCCCCCCEEEEECHHHHHHHHHHHCCCCCHHHCCEEEEEEECCCCHHHHHHHH
QRRQPPDMLLTTPEQLTLLLATADAEHLFADVRRVIFDELHAIAPSKRGDLLSLGLARLR
HHCCCCCCEEECHHHEEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
TLAPMMRTTGLSATVRAPEDLQRWLVSQQDANALATLITAPPGAPADLRILDSDNALPWA
HHHHHHHHCCCCEEECCHHHHHHHHHCCCCCHHHHHEEECCCCCCCCEEEEECCCCCCCC
GHSAAHALREIYAAIEAATMTLVFVNTRAQAEYVFQELWRINEKSLPIALHHGSLDAGQR
CCHHHHHHHHHHHHHHHHEEEEEEEECCHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCH
RKVEAAMVQNRLKAVVCTSTLDLGIDWGAVDLVINVGAPKGASRLAQRIGRANHRLDEPS
HHHHHHHHHHHHHHEEEECHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCC
RALLVPANRFEVLECHAAVEAARAGTQDTAAARAGALDVLCQHLLGMACVGPFDPQRLYE
CEEEEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
EVITAAPYAGLSRKDFDAALNFAAHGGYALKAYERFAKLKPMPDGRWRIANGRVAQAYRM
HHHHHCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCEEECCCCEEHHHCC
NCGTIVEADMLRVRLVPGSEGGRRKSGQPLKTAYTGPLRRGGRILGEIEDYFIETLRPKD
CCCCEEECCEEEEEEECCCCCCCCCCCCCCHHHCCCCHHHCCHHHHHHHHHHHHHCCCCC
TFLFGGEILALQGIAGDEALVVRSHAETPKIPSYAGGKFPLSTYLAKRVRELLSTPEEWN
CEEECCEEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHH
QLPPQVVEWLALQKHVSRLPPPEALLVETFARGGHFHLVAYPFEGRLAHQTLGMLLTRRM
CCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHH
ERAGLQPLGFVANDYALCVWSRADVGAWCEDNKYALNALFAKDMLGDDLEEWLHESALMK
HHCCCCCCCEECCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHH
RTFRNCAIIAGLIERNFPGKQKAGRQESRRVTISTDLIYDVLRRHEPDHVLLRAARADAA
HHHHHHHHHHHHHHCCCCCHHHCCCHHHCEEEEEHHHHHHHHHCCCCCHHHHHHHHHHHH
TGLLDLERLGLMLARVRHKIIHQPLTHISPLAVPIMLEIGRERVYGEAQDALLAEAAADL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
AAEAMAP
HHHHCCC
>Mature Secondary Structure
MKRGLIQKEPLPPRFAAWFAARGWSPRAHQQHLLALAQQQENALLIAPTGAGKTLAGFLP
CCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHH
SLVDLEQKRNRDGLHTLYISPLKALAVDVERNLQMPIAEMGLKITVETRTGDTSTAKRLR
HHHHHHHHCCCCCCEEEEECHHHHHHHHHHHCCCCCHHHCCEEEEEEECCCCHHHHHHHH
QRRQPPDMLLTTPEQLTLLLATADAEHLFADVRRVIFDELHAIAPSKRGDLLSLGLARLR
HHCCCCCCEEECHHHEEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
TLAPMMRTTGLSATVRAPEDLQRWLVSQQDANALATLITAPPGAPADLRILDSDNALPWA
HHHHHHHHCCCCEEECCHHHHHHHHHCCCCCHHHHHEEECCCCCCCCEEEEECCCCCCCC
GHSAAHALREIYAAIEAATMTLVFVNTRAQAEYVFQELWRINEKSLPIALHHGSLDAGQR
CCHHHHHHHHHHHHHHHHEEEEEEEECCHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCH
RKVEAAMVQNRLKAVVCTSTLDLGIDWGAVDLVINVGAPKGASRLAQRIGRANHRLDEPS
HHHHHHHHHHHHHHEEEECHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCC
RALLVPANRFEVLECHAAVEAARAGTQDTAAARAGALDVLCQHLLGMACVGPFDPQRLYE
CEEEEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
EVITAAPYAGLSRKDFDAALNFAAHGGYALKAYERFAKLKPMPDGRWRIANGRVAQAYRM
HHHHHCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCEEECCCCEEHHHCC
NCGTIVEADMLRVRLVPGSEGGRRKSGQPLKTAYTGPLRRGGRILGEIEDYFIETLRPKD
CCCCEEECCEEEEEEECCCCCCCCCCCCCCHHHCCCCHHHCCHHHHHHHHHHHHHCCCCC
TFLFGGEILALQGIAGDEALVVRSHAETPKIPSYAGGKFPLSTYLAKRVRELLSTPEEWN
CEEECCEEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHH
QLPPQVVEWLALQKHVSRLPPPEALLVETFARGGHFHLVAYPFEGRLAHQTLGMLLTRRM
CCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHH
ERAGLQPLGFVANDYALCVWSRADVGAWCEDNKYALNALFAKDMLGDDLEEWLHESALMK
HHCCCCCCCEECCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHH
RTFRNCAIIAGLIERNFPGKQKAGRQESRRVTISTDLIYDVLRRHEPDHVLLRAARADAA
HHHHHHHHHHHHHHCCCCCHHHCCCHHHCEEEEEHHHHHHHHHCCCCCHHHHHHHHHHHH
TGLLDLERLGLMLARVRHKIIHQPLTHISPLAVPIMLEIGRERVYGEAQDALLAEAAADL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
AAEAMAP
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on acid anhydrides [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]