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The map label for this gene is nudC [H]

Identifier: 182677256

GI number: 182677256

Start: 295523

End: 296500

Strand: Direct

Name: nudC [H]

Synonym: Bind_0257

Alternate gene names: 182677256

Gene position: 295523-296500 (Clockwise)

Preceding gene: 182677250

Following gene: 182677257

Centisome position: 7.09

GC content: 61.76

Gene sequence:

>978_bases
ATGGCCGCGATAAAACCTTATCTCTTTGCGGTCGAGCCCACGCCTTCCGAGCCTTCGGCGGAAACGGGTTTCGCCTTGAA
CGGGCTCGACCGTCTGTCGCAACGGCGCGAGGATGCCAATTTTCTACAGGCGATGACGGAGGCGCCCTCGACCCGCACCC
TCGTCTTTTCAGGCGACATTCCCGTGCTGAAACGTTGCGGGACGGTACATGAGGCGACCTTTACCCTCGCCGAGGCGGCC
CATCTCGGCATTGCCCGGGAAGCTGCCTTTCTTGGCGTCGATGCGGCCGGCGAGGCCCTATTTGCTTTATTGCTCGAAAG
CGTCCTGCCGGAAAAGCAGCAGGAGCGCGACGATATTGCCATGATCGATTTGCGCACCATTGCCCTGCAAGGACTGGTCG
CGCCATTTATGCTCGGTCGGCTCGGTGAGGCCAAGAGCCTGCTCTACTGGCATTCGCGGCATCGTTTCTGCGCCAATTGC
GGGACGAAAACGCAAGTCTCCGTTTCCGGCTGGCGGCGTCATTGCCCGGCTTGCGAGGCCTCGCATTTTCCCCGCACCGA
TCCGGTCGTGATCATGCTGGTGCAAGACGGCGCGCATTGCCTGCTCGGACGGCAGGCGGCTTTTCCGCCGCGCATGGTCT
CCTGTCTTGCGGGATTCATGGAATCAGGGGAAACGATAGAGGATGCCGTGCGCCGCGAGGTTTTTGAGGAAGTGGGCATC
GGTGTCGGCAAGGTGACCTATTTCGCCTCGCAGCCCTGGCCGTTTCCAGCCTCGTTGATGATCGGTTGCCTCGCCGAGGC
GCGGAGCCGGGATCTGGTGCTCGATCACGAGGAACTCGAGGATGCGCGCTGGTATTCCCGCGCCGAAGTGCGCCAGATGC
TGGAGGCGCCCCTGCCGGAAGGGCCGATCTGCCCGCCGAAATTGAGTATCGCCAATTTGCTCCTGCGCCGCTGGGCTTCC
GAGAGTTTAACCTTTTGA

Upstream 100 bases:

>100_bases
ATCTTAGATTCTCGATCCGTCATTTTTAAACCGTATCCACTTATCCTCAATGAACCACGACGAGTCGCGCTTCAATGAGG
GTGGATACGAGGAGGAAATC

Downstream 100 bases:

>100_bases
CTTTGGCGCCGCCCTGTTGAACATGCCCGGATTTCACGAAAGCGACGGGATAGACAGCCATGCCGGAACACAGTTCAGAC
ACGGGCAACAACAAGGCCCT

Product: NUDIX hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MAAIKPYLFAVEPTPSEPSAETGFALNGLDRLSQRREDANFLQAMTEAPSTRTLVFSGDIPVLKRCGTVHEATFTLAEAA
HLGIAREAAFLGVDAAGEALFALLLESVLPEKQQERDDIAMIDLRTIALQGLVAPFMLGRLGEAKSLLYWHSRHRFCANC
GTKTQVSVSGWRRHCPACEASHFPRTDPVVIMLVQDGAHCLLGRQAAFPPRMVSCLAGFMESGETIEDAVRREVFEEVGI
GVGKVTYFASQPWPFPASLMIGCLAEARSRDLVLDHEELEDARWYSRAEVRQMLEAPLPEGPICPPKLSIANLLLRRWAS
ESLTF

Sequences:

>Translated_325_residues
MAAIKPYLFAVEPTPSEPSAETGFALNGLDRLSQRREDANFLQAMTEAPSTRTLVFSGDIPVLKRCGTVHEATFTLAEAA
HLGIAREAAFLGVDAAGEALFALLLESVLPEKQQERDDIAMIDLRTIALQGLVAPFMLGRLGEAKSLLYWHSRHRFCANC
GTKTQVSVSGWRRHCPACEASHFPRTDPVVIMLVQDGAHCLLGRQAAFPPRMVSCLAGFMESGETIEDAVRREVFEEVGI
GVGKVTYFASQPWPFPASLMIGCLAEARSRDLVLDHEELEDARWYSRAEVRQMLEAPLPEGPICPPKLSIANLLLRRWAS
ESLTF
>Mature_324_residues
AAIKPYLFAVEPTPSEPSAETGFALNGLDRLSQRREDANFLQAMTEAPSTRTLVFSGDIPVLKRCGTVHEATFTLAEAAH
LGIAREAAFLGVDAAGEALFALLLESVLPEKQQERDDIAMIDLRTIALQGLVAPFMLGRLGEAKSLLYWHSRHRFCANCG
TKTQVSVSGWRRHCPACEASHFPRTDPVVIMLVQDGAHCLLGRQAAFPPRMVSCLAGFMESGETIEDAVRREVFEEVGIG
VGKVTYFASQPWPFPASLMIGCLAEARSRDLVLDHEELEDARWYSRAEVRQMLEAPLPEGPICPPKLSIANLLLRRWASE
SLTF

Specific function: Unknown

COG id: COG2816

COG function: function code L; NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI13899267, Length=339, Percent_Identity=38.3480825958702, Blast_Score=207, Evalue=7e-54,
Organism=Homo sapiens, GI50593112, Length=247, Percent_Identity=37.246963562753, Blast_Score=156, Evalue=2e-38,
Organism=Escherichia coli, GI48994995, Length=239, Percent_Identity=31.7991631799163, Blast_Score=117, Evalue=9e-28,
Organism=Caenorhabditis elegans, GI71986510, Length=225, Percent_Identity=30.6666666666667, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI212645999, Length=225, Percent_Identity=30.6666666666667, Blast_Score=100, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6321371, Length=176, Percent_Identity=37.5, Blast_Score=110, Evalue=4e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015375
- InterPro:   IPR022925
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR015376 [H]

Pfam domain/function: PF00293 NUDIX; PF09296 NUDIX-like; PF09297 zf-NADH-PPase [H]

EC number: =3.6.1.22 [H]

Molecular weight: Translated: 35794; Mature: 35662

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAIKPYLFAVEPTPSEPSAETGFALNGLDRLSQRREDANFLQAMTEAPSTRTLVFSGDI
CCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCC
PVLKRCGTVHEATFTLAEAAHLGIAREAAFLGVDAAGEALFALLLESVLPEKQQERDDIA
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHCCCCEE
MIDLRTIALQGLVAPFMLGRLGEAKSLLYWHSRHRFCANCGTKTQVSVSGWRRHCPACEA
EHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHCCCCCCEEEHHHHHHCCCCCCC
SHFPRTDPVVIMLVQDGAHCLLGRQAAFPPRMVSCLAGFMESGETIEDAVRREVFEEVGI
CCCCCCCCEEEEEECCCCCEECCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCC
GVGKVTYFASQPWPFPASLMIGCLAEARSRDLVLDHEELEDARWYSRAEVRQMLEAPLPE
CCCCEEEECCCCCCCHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHHHHHCCCCC
GPICPPKLSIANLLLRRWASESLTF
CCCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AAIKPYLFAVEPTPSEPSAETGFALNGLDRLSQRREDANFLQAMTEAPSTRTLVFSGDI
CCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCC
PVLKRCGTVHEATFTLAEAAHLGIAREAAFLGVDAAGEALFALLLESVLPEKQQERDDIA
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHCCCCEE
MIDLRTIALQGLVAPFMLGRLGEAKSLLYWHSRHRFCANCGTKTQVSVSGWRRHCPACEA
EHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHCCCCCCEEEHHHHHHCCCCCCC
SHFPRTDPVVIMLVQDGAHCLLGRQAAFPPRMVSCLAGFMESGETIEDAVRREVFEEVGI
CCCCCCCCEEEEEECCCCCEECCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCC
GVGKVTYFASQPWPFPASLMIGCLAEARSRDLVLDHEELEDARWYSRAEVRQMLEAPLPE
CCCCEEEECCCCCCCHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHHHHHCCCCC
GPICPPKLSIANLLLRRWASESLTF
CCCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]