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The map label for this gene is fbcH [H]

Identifier: 182677156

GI number: 182677156

Start: 184653

End: 185909

Strand: Direct

Name: fbcH [H]

Synonym: Bind_0155

Alternate gene names: 182677156

Gene position: 184653-185909 (Clockwise)

Preceding gene: 182677155

Following gene: 182677157

Centisome position: 4.43

GC content: 58.0

Gene sequence:

>1257_bases
ATGAGCGGATCTTCAACTTATGTCCCGAAAAGCGGCCTGGCTCGATGGTTCGAGAGCCGGCTTCCGATCGTGGGATTGAT
ACATTCCTCGTTCATCGTCTTTCCGACGCCGCGCAATCTCAATTATTGGTGGACGTTCGGCGGCATCTTGACCTTCATGC
TGGTCGCGCAGATCGTGACCGGTGTCGTGCTGGTCATGCATTATACGCCGGAAACGACCCTGGCCTTCGCCTCCGTCGAA
CATATCATGCGCGACGTGAACTATGGCTGGCTGCTGCGTTATGCCCATGCCAACGGCGCCTCGATGTTCTTCATCGCCGT
TTATATCCACATGCTGCGCGGGCTTTATTATGGCTCCTATAAGGCGCCGCGCGAGGTTTTGTGGATCATCGGCGTGATCA
TCTATCTGTTGATGATGGCCACCGGCTTCATGGGTTATGTGCTTCCCTGGGGTCAGATGAGCTTCTGGGGCGCCACCGTC
ATCACCAGCCTGTTCTCGGCGATTCCCTTCGTCGGTGATACGATCACCACTTGGCTGTGGGGCGGTTTCGCGGTCGATAA
TCCGACGCTCAACCGGTTCTTCTCGCTGCATTACCTGCTGCCCTTCATGATCGCCGGCGTTGTCGTCCTGCATATCTGGG
CCTTGCATGTTCCTGGCTCGAACAATCCGGCGGGTCTCGACGTCAAAACCCCCAAGGACACACTGCCCTTCCATCCCTAT
TTCACCATCAAGGATGGGTTCGGCCTCGTCTGCTTCCTGGTCTTCTTCTCCTGGTGGGTCTTCTATGTGCCGAATTATCT
CGGCCATGCGGACAATTACATCGAAGCCAACCCGATGCAGACGCCCGCCCATATCGTGCCGGAATGGTATTATCTGCCCT
TCTACGCGATCCTGCGGTCGATTCCCTCCAAGCTCGGCGGCGTCATCGCGATGTTCAGCGCGATCCTGGTCTTCGCCTTC
CTGCCCTGGCTCGATACGTCGCGGGTTCGCTCCGCCGCTTATCGTCCGGTCTACCGCTTCTTCTTCTGGGTCTTCGTCGT
CTGCGCCCTGCTGCTTGGCTATATCGGCGCCCAGCCCCCGGAAGGCGGTTATGTGCTCGCTGGCCAGCTTCTCACCGCTT
ATTATTTCTTGCACTTCCTGGTGATTCTGCCGCTGATCGGCCTGTTCGAGACGCCGCGTGAACTGCCTGCGTCCATCGCG
GATGCCGTCCTCGGCAAACACGAGGTTGCCGCAACGGCCAGTGCGACCACACACTAA

Upstream 100 bases:

>100_bases
CCCCGATCTTTCCCTTTAGCCTTGTGACTGTGTTCCTCACGCCTCGCTCGGTCGTGAAGAGCCAGTCCAAGGCGAAACCC
TGAAAGAAGAGACGAGACCG

Downstream 100 bases:

>100_bases
GCTGAAACCAAACAGACACGCGGATGAGACCTGATCGAATGGGTCTCATCCAGCCTGACCAAGACCTAAGGTTTTGGTCA
GGCATTGAAGCAACATCATG

Product: cytochrome b/b6 domain-containing protein

Products: Q; ferrocytochrome c

Alternate protein names: NA

Number of amino acids: Translated: 418; Mature: 417

Protein sequence:

>418_residues
MSGSSTYVPKSGLARWFESRLPIVGLIHSSFIVFPTPRNLNYWWTFGGILTFMLVAQIVTGVVLVMHYTPETTLAFASVE
HIMRDVNYGWLLRYAHANGASMFFIAVYIHMLRGLYYGSYKAPREVLWIIGVIIYLLMMATGFMGYVLPWGQMSFWGATV
ITSLFSAIPFVGDTITTWLWGGFAVDNPTLNRFFSLHYLLPFMIAGVVVLHIWALHVPGSNNPAGLDVKTPKDTLPFHPY
FTIKDGFGLVCFLVFFSWWVFYVPNYLGHADNYIEANPMQTPAHIVPEWYYLPFYAILRSIPSKLGGVIAMFSAILVFAF
LPWLDTSRVRSAAYRPVYRFFFWVFVVCALLLGYIGAQPPEGGYVLAGQLLTAYYFLHFLVILPLIGLFETPRELPASIA
DAVLGKHEVAATASATTH

Sequences:

>Translated_418_residues
MSGSSTYVPKSGLARWFESRLPIVGLIHSSFIVFPTPRNLNYWWTFGGILTFMLVAQIVTGVVLVMHYTPETTLAFASVE
HIMRDVNYGWLLRYAHANGASMFFIAVYIHMLRGLYYGSYKAPREVLWIIGVIIYLLMMATGFMGYVLPWGQMSFWGATV
ITSLFSAIPFVGDTITTWLWGGFAVDNPTLNRFFSLHYLLPFMIAGVVVLHIWALHVPGSNNPAGLDVKTPKDTLPFHPY
FTIKDGFGLVCFLVFFSWWVFYVPNYLGHADNYIEANPMQTPAHIVPEWYYLPFYAILRSIPSKLGGVIAMFSAILVFAF
LPWLDTSRVRSAAYRPVYRFFFWVFVVCALLLGYIGAQPPEGGYVLAGQLLTAYYFLHFLVILPLIGLFETPRELPASIA
DAVLGKHEVAATASATTH
>Mature_417_residues
SGSSTYVPKSGLARWFESRLPIVGLIHSSFIVFPTPRNLNYWWTFGGILTFMLVAQIVTGVVLVMHYTPETTLAFASVEH
IMRDVNYGWLLRYAHANGASMFFIAVYIHMLRGLYYGSYKAPREVLWIIGVIIYLLMMATGFMGYVLPWGQMSFWGATVI
TSLFSAIPFVGDTITTWLWGGFAVDNPTLNRFFSLHYLLPFMIAGVVVLHIWALHVPGSNNPAGLDVKTPKDTLPFHPYF
TIKDGFGLVCFLVFFSWWVFYVPNYLGHADNYIEANPMQTPAHIVPEWYYLPFYAILRSIPSKLGGVIAMFSAILVFAFL
PWLDTSRVRSAAYRPVYRFFFWVFVVCALLLGYIGAQPPEGGYVLAGQLLTAYYFLHFLVILPLIGLFETPRELPASIAD
AVLGKHEVAATASATTH

Specific function: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. c1 functions as an electron donor to cytochrome c [H]

COG id: COG1290

COG function: function code C; Cytochrome b subunit of the bc complex

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cytochrome c domain [H]

Homologues:

Organism=Homo sapiens, GI251831119, Length=370, Percent_Identity=50.5405405405405, Blast_Score=368, Evalue=1e-102,
Organism=Saccharomyces cerevisiae, GI6226529, Length=368, Percent_Identity=55.7065217391304, Blast_Score=389, Evalue=1e-109,
Organism=Saccharomyces cerevisiae, GI6226532, Length=246, Percent_Identity=54.8780487804878, Blast_Score=278, Evalue=1e-75,
Organism=Saccharomyces cerevisiae, GI6226531, Length=165, Percent_Identity=58.1818181818182, Blast_Score=201, Evalue=1e-52,
Organism=Saccharomyces cerevisiae, GI6226530, Length=140, Percent_Identity=54.2857142857143, Blast_Score=154, Evalue=3e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016175
- InterPro:   IPR005798
- InterPro:   IPR005797
- InterPro:   IPR002326
- InterPro:   IPR021157
- InterPro:   IPR009056
- InterPro:   IPR016174 [H]

Pfam domain/function: PF00032 Cytochrom_B_C; PF00033 Cytochrom_B_N; PF02167 Cytochrom_C1 [H]

EC number: 1.10.2.2

Molecular weight: Translated: 47092; Mature: 46961

Theoretical pI: Translated: 8.51; Mature: 8.51

Prosite motif: PS51002 CYTB_NTER ; PS51003 CYTB_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGSSTYVPKSGLARWFESRLPIVGLIHSSFIVFPTPRNLNYWWTFGGILTFMLVAQIVT
CCCCCCCCCHHHHHHHHHHCCCEEEEECCCEEEEECCCCCCEEEHHHHHHHHHHHHHHHH
GVVLVMHYTPETTLAFASVEHIMRDVNYGWLLRYAHANGASMFFIAVYIHMLRGLYYGSY
HHHHHHEECCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCC
KAPREVLWIIGVIIYLLMMATGFMGYVLPWGQMSFWGATVITSLFSAIPFVGDTITTWLW
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHH
GGFAVDNPTLNRFFSLHYLLPFMIAGVVVLHIWALHVPGSNNPAGLDVKTPKDTLPFHPY
CCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCE
FTIKDGFGLVCFLVFFSWWVFYVPNYLGHADNYIEANPMQTPAHIVPEWYYLPFYAILRS
EEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHH
IPSKLGGVIAMFSAILVFAFLPWLDTSRVRSAAYRPVYRFFFWVFVVCALLLGYIGAQPP
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
EGGYVLAGQLLTAYYFLHFLVILPLIGLFETPRELPASIADAVLGKHEVAATASATTH
CCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHCCCCCCC
>Mature Secondary Structure 
SGSSTYVPKSGLARWFESRLPIVGLIHSSFIVFPTPRNLNYWWTFGGILTFMLVAQIVT
CCCCCCCCHHHHHHHHHHCCCEEEEECCCEEEEECCCCCCEEEHHHHHHHHHHHHHHHH
GVVLVMHYTPETTLAFASVEHIMRDVNYGWLLRYAHANGASMFFIAVYIHMLRGLYYGSY
HHHHHHEECCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCC
KAPREVLWIIGVIIYLLMMATGFMGYVLPWGQMSFWGATVITSLFSAIPFVGDTITTWLW
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHH
GGFAVDNPTLNRFFSLHYLLPFMIAGVVVLHIWALHVPGSNNPAGLDVKTPKDTLPFHPY
CCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCE
FTIKDGFGLVCFLVFFSWWVFYVPNYLGHADNYIEANPMQTPAHIVPEWYYLPFYAILRS
EEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHH
IPSKLGGVIAMFSAILVFAFLPWLDTSRVRSAAYRPVYRFFFWVFVVCALLLGYIGAQPP
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
EGGYVLAGQLLTAYYFLHFLVILPLIGLFETPRELPASIADAVLGKHEVAATASATTH
CCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: QH2; ferricytochrome c

Specific reaction: QH2 + 2 ferricytochrome c = Q + 2 ferrocytochrome c

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2541921; 12597275 [H]