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The map label for this gene is fbcH [H]

Identifier: 182677157

GI number: 182677157

Start: 186077

End: 186934

Strand: Direct

Name: fbcH [H]

Synonym: Bind_0156

Alternate gene names: 182677157

Gene position: 186077-186934 (Clockwise)

Preceding gene: 182677156

Following gene: 182677159

Centisome position: 4.46

GC content: 59.79

Gene sequence:

>858_bases
ATGAGTCTTTTCAAAAGCGGCAATGGGCGCGGGAAAAGCTGGATGTCGCGGATCGTCGCGGCGGGTTTGCTTCTTTCGGC
CTCCGGCATGTCTGCCTTCGCTGAAGAAGGCGGCGCGGAAACCGCGCATCCGAAGCCGCCGCGCCAGGAATGGAGCTTTG
GCGGGCCTTTGGGCAAATATGACCAGGCTCAATTGCAGCGCGGCTTTCAGGTGTTCCGCGAGGTTTGCTCCAATTGCCAT
GCGGCGAAATTCCTGAACTTCCGCAATCTCTCTGAGTCGGGTGGCCCCGGCTTCACCCCGGCCCAGGTCAAGGCGCTGGC
GGCGCAATATAAGATCAAGGACGGCCCCAACGAGGCCGGCGAAATGTTCGAGCGTCCCGGCCGTCCTTCGGATGCCTTCC
CCTGGACCTTCGCCAATCCTCAGGCCGCGACCGCCGCTCTCGGGGCTCTGCCGCCCGATATGTCGGTTCTGGCCAAGGCG
CGGACCTATCAGCGCGGCTTCCCGCTGTTCCTGGTTGATCCGTTTATCCAATATCAGGAGCATGGCGCCGATTACATTTA
TGCGCTCCTGAACGGCTATACGAATGAGAAAGACCCGAACTGGAACGAGTTCATGCCGGGTCATAAGATCGCCATGCCGA
AGCCTTTGAGCGATGGTCTTGTCGCTTATACCGACGGCACACCGCAGACGGCCCAGCAATATGCCAAGGACGTCACCTCC
TTCCTGATGTGGATGGCGGAGCCGAAGCTCGAGGAACGCAAGAAGTTCGGTTTCCGGGTCGTGATCTTCTTGGCGGTCTT
CGCGGCCATGCTCTATTTCGTGAAGCGCAAAGTCTGGTCGAGCGTCCACGGACATTGA

Upstream 100 bases:

>100_bases
AAGGTTTTGGTCAGGCATTGAAGCAACATCATGCGCGATGCCGGATCGAAGTGAGAAGAGATCCTGGTCCAGCGGTCGAT
AGGCACGAGGAAAGAAGAGG

Downstream 100 bases:

>100_bases
TCTACGACAGTTCACACTGTTCTTAACAACATCGGCCCCGAAGCGAATGCGTTTCGGGGCCGATGTTTTTTGGGCTCATC
GATAGAGCACTTCCTTCTGG

Product: cytochrome c1

Products: Q; ferrocytochrome c

Alternate protein names: NA

Number of amino acids: Translated: 285; Mature: 284

Protein sequence:

>285_residues
MSLFKSGNGRGKSWMSRIVAAGLLLSASGMSAFAEEGGAETAHPKPPRQEWSFGGPLGKYDQAQLQRGFQVFREVCSNCH
AAKFLNFRNLSESGGPGFTPAQVKALAAQYKIKDGPNEAGEMFERPGRPSDAFPWTFANPQAATAALGALPPDMSVLAKA
RTYQRGFPLFLVDPFIQYQEHGADYIYALLNGYTNEKDPNWNEFMPGHKIAMPKPLSDGLVAYTDGTPQTAQQYAKDVTS
FLMWMAEPKLEERKKFGFRVVIFLAVFAAMLYFVKRKVWSSVHGH

Sequences:

>Translated_285_residues
MSLFKSGNGRGKSWMSRIVAAGLLLSASGMSAFAEEGGAETAHPKPPRQEWSFGGPLGKYDQAQLQRGFQVFREVCSNCH
AAKFLNFRNLSESGGPGFTPAQVKALAAQYKIKDGPNEAGEMFERPGRPSDAFPWTFANPQAATAALGALPPDMSVLAKA
RTYQRGFPLFLVDPFIQYQEHGADYIYALLNGYTNEKDPNWNEFMPGHKIAMPKPLSDGLVAYTDGTPQTAQQYAKDVTS
FLMWMAEPKLEERKKFGFRVVIFLAVFAAMLYFVKRKVWSSVHGH
>Mature_284_residues
SLFKSGNGRGKSWMSRIVAAGLLLSASGMSAFAEEGGAETAHPKPPRQEWSFGGPLGKYDQAQLQRGFQVFREVCSNCHA
AKFLNFRNLSESGGPGFTPAQVKALAAQYKIKDGPNEAGEMFERPGRPSDAFPWTFANPQAATAALGALPPDMSVLAKAR
TYQRGFPLFLVDPFIQYQEHGADYIYALLNGYTNEKDPNWNEFMPGHKIAMPKPLSDGLVAYTDGTPQTAQQYAKDVTSF
LMWMAEPKLEERKKFGFRVVIFLAVFAAMLYFVKRKVWSSVHGH

Specific function: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. c1 functions as an electron donor to cytochrome c [H]

COG id: COG2857

COG function: function code C; Cytochrome c1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cytochrome c domain [H]

Homologues:

Organism=Homo sapiens, GI21359867, Length=284, Percent_Identity=35.5633802816901, Blast_Score=166, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI17506225, Length=285, Percent_Identity=31.9298245614035, Blast_Score=124, Evalue=7e-29,
Organism=Saccharomyces cerevisiae, GI6324639, Length=291, Percent_Identity=37.4570446735395, Blast_Score=181, Evalue=2e-46,
Organism=Drosophila melanogaster, GI24658292, Length=284, Percent_Identity=34.1549295774648, Blast_Score=160, Evalue=1e-39,
Organism=Drosophila melanogaster, GI21358225, Length=288, Percent_Identity=32.9861111111111, Blast_Score=157, Evalue=8e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016175
- InterPro:   IPR005798
- InterPro:   IPR005797
- InterPro:   IPR002326
- InterPro:   IPR021157
- InterPro:   IPR009056
- InterPro:   IPR016174 [H]

Pfam domain/function: PF00032 Cytochrom_B_C; PF00033 Cytochrom_B_N; PF02167 Cytochrom_C1 [H]

EC number: 1.10.2.2

Molecular weight: Translated: 31546; Mature: 31415

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: PS51007 CYTC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLFKSGNGRGKSWMSRIVAAGLLLSASGMSAFAEEGGAETAHPKPPRQEWSFGGPLGKY
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
DQAQLQRGFQVFREVCSNCHAAKFLNFRNLSESGGPGFTPAQVKALAAQYKIKDGPNEAG
HHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHH
EMFERPGRPSDAFPWTFANPQAATAALGALPPDMSVLAKARTYQRGFPLFLVDPFIQYQE
HHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEECHHHHHHH
HGADYIYALLNGYTNEKDPNWNEFMPGHKIAMPKPLSDGLVAYTDGTPQTAQQYAKDVTS
CCHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHH
FLMWMAEPKLEERKKFGFRVVIFLAVFAAMLYFVKRKVWSSVHGH
HHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SLFKSGNGRGKSWMSRIVAAGLLLSASGMSAFAEEGGAETAHPKPPRQEWSFGGPLGKY
CCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
DQAQLQRGFQVFREVCSNCHAAKFLNFRNLSESGGPGFTPAQVKALAAQYKIKDGPNEAG
HHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHH
EMFERPGRPSDAFPWTFANPQAATAALGALPPDMSVLAKARTYQRGFPLFLVDPFIQYQE
HHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEECHHHHHHH
HGADYIYALLNGYTNEKDPNWNEFMPGHKIAMPKPLSDGLVAYTDGTPQTAQQYAKDVTS
CCHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHH
FLMWMAEPKLEERKKFGFRVVIFLAVFAAMLYFVKRKVWSSVHGH
HHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: QH2; ferricytochrome c

Specific reaction: QH2 + 2 ferricytochrome c = Q + 2 ferrocytochrome c

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2541921; 12597275 [H]