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The map label for this gene is grxD [H]

Identifier: 182682644

GI number: 182682644

Start: 2406138

End: 2406452

Strand: Reverse

Name: grxD [H]

Synonym: XfasM23_2134

Alternate gene names: 182682644

Gene position: 2406452-2406138 (Counterclockwise)

Preceding gene: 182682645

Following gene: 182682643

Centisome position: 94.9

GC content: 49.52

Gene sequence:

>315_bases
ATGTTGGTGATGGAGCGGATCCAGGCTGAAATTGAAGAGCATCCATTGGTGTTATTCATGAAAGGGACGCTTGAATTTCC
GATGTGTGGTTATTCCAGCAGAGCGACACAGGCGTTGCTTGCTGCTGGCGCTCGTCATTTGCATATTGTGAACGTGCTTG
CCGAAGCAGAGATTCGTGCCAATTTGCCACGCTTCTCCAATTGGCTGACTTTCCCGCAGCTGTTCATTCATGGAGAATTG
ATCGGTGGCTGCGAGATCATCTTGGAGCTGTTTGAATCTGGCGATCTGAAGCGTATTCTCAGCGAGGCTGATTAG

Upstream 100 bases:

>100_bases
GGTGTGAGACTTTGTTAGGAATACGGTGGTTACAATGTCGCCCTGTGTCGTAGACATCTGATTAGCGGTTACGGGACCTG
CCTCATGTTGGGAGAATCGT

Downstream 100 bases:

>100_bases
GCTTGAGTGCATATGTGTTGTAGCAAACCGTACTGAAAGGTTGCCTGGTGTGGGCAGCGGGTGTGAATGGAGGTTACAGC
GCACATCTGGGCCGCAGGCC

Product: glutaredoxin-like protein

Products: NA

Alternate protein names: Grx4; Monothiol glutaredoxin [H]

Number of amino acids: Translated: 104; Mature: 104

Protein sequence:

>104_residues
MLVMERIQAEIEEHPLVLFMKGTLEFPMCGYSSRATQALLAAGARHLHIVNVLAEAEIRANLPRFSNWLTFPQLFIHGEL
IGGCEIILELFESGDLKRILSEAD

Sequences:

>Translated_104_residues
MLVMERIQAEIEEHPLVLFMKGTLEFPMCGYSSRATQALLAAGARHLHIVNVLAEAEIRANLPRFSNWLTFPQLFIHGEL
IGGCEIILELFESGDLKRILSEAD
>Mature_104_residues
MLVMERIQAEIEEHPLVLFMKGTLEFPMCGYSSRATQALLAAGARHLHIVNVLAEAEIRANLPRFSNWLTFPQLFIHGEL
IGGCEIILELFESGDLKRILSEAD

Specific function: Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters [H]

COG id: COG0278

COG function: function code O; Glutaredoxin-related protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutaredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI42516576, Length=92, Percent_Identity=40.2173913043478, Blast_Score=91, Evalue=2e-19,
Organism=Homo sapiens, GI95113651, Length=96, Percent_Identity=37.5, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1787943, Length=100, Percent_Identity=46, Blast_Score=117, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17556042, Length=101, Percent_Identity=34.6534653465347, Blast_Score=79, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71988153, Length=96, Percent_Identity=38.5416666666667, Blast_Score=75, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6325198, Length=104, Percent_Identity=44.2307692307692, Blast_Score=89, Evalue=8e-20,
Organism=Saccharomyces cerevisiae, GI6320303, Length=87, Percent_Identity=39.0804597701149, Blast_Score=68, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6321022, Length=82, Percent_Identity=39.0243902439024, Blast_Score=67, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24642023, Length=93, Percent_Identity=35.4838709677419, Blast_Score=77, Evalue=3e-15,
Organism=Drosophila melanogaster, GI19921242, Length=97, Percent_Identity=36.0824742268041, Blast_Score=75, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002109
- InterPro:   IPR014434
- InterPro:   IPR004480
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00462 Glutaredoxin [H]

EC number: NA

Molecular weight: Translated: 11693; Mature: 11693

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVMERIQAEIEEHPLVLFMKGTLEFPMCGYSSRATQALLAAGARHLHIVNVLAEAEIRA
CCHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHC
NLPRFSNWLTFPQLFIHGELIGGCEIILELFESGDLKRILSEAD
CCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHCCC
>Mature Secondary Structure
MLVMERIQAEIEEHPLVLFMKGTLEFPMCGYSSRATQALLAAGARHLHIVNVLAEAEIRA
CCHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHC
NLPRFSNWLTFPQLFIHGELIGGCEIILELFESGDLKRILSEAD
CCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]