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The map label for this gene is engD [H]

Identifier: 182682627

GI number: 182682627

Start: 2386125

End: 2387216

Strand: Reverse

Name: engD [H]

Synonym: XfasM23_2115

Alternate gene names: 182682627

Gene position: 2387216-2386125 (Counterclockwise)

Preceding gene: 182682628

Following gene: 182682626

Centisome position: 94.14

GC content: 49.08

Gene sequence:

>1092_bases
ATGGGTATTAAATGCGGTATCGTTGGGTTGCCTAATGTTGGTAAGTCGACTTTGTTCAATGCGTTGACTAAAGCTGGTAT
CGCTGCCGCTAACTTCCCATTCTGTACAATTGAGCCTAACGTAGGTGTCGTGTCTGTTCCTGATCCTCGTCTTAATCAAT
TGGCCGAAATCGTCAAGCCTCAGAAGTTACTGCCGACGGTGATTGAGTTCGTTGATATTGCAGGTTTGGTTGCTGGTGCG
GCTAGTGGTGAAGGGTTAGGCAATAAGTTTTTAGCGCATATTCGCGAGGTTGATGCGATCGCTCATGTAGTTCGTTGTTT
CGAACATGGTGAAATTATTCATGTTGCCGGTAAGGTTGATCCTCTGGCTGACATTGAAATCATTGATACGGAATTGATAC
TGGCCGATCTCGACACTGTCGAGAAGGCGTGCAACCGTATCATGCGTGCTGCCAAAGGGGGGGGGGGGGAGGCGATTGCC
CGCAAGTCTGTGCTTGAGAGATTGCAGGTTGCGCTTAATGAAGGCAAATCTGCTCGCTCTGCTGGTTTGGATGAGGATGA
ACGTGCTTTAGTCCGCGATTTGTTCTTGCTGACGCTCAAGCCGGTGATGTATATCGCTAATGTGCTTGAAAATGGGTTTC
AGGATAATGTTTATCTTGAGGCTTTACGTGTCCGTGCTTCCTCTGATAATGCTCAGTTAGTGCCGATTTCTGCAGTGATC
GAAGAGGAGCTGGCTCAGCTTGAGGATGTGGATCGCGATGCATTTTTGGTTGACCTTGGTCTGGAGGAGCCGGGGTTGAA
TCGAGTAGTTCGTGCTGCTTATGCGTTGCTAGGTTTGCAGACTTACTTTACTGCGGGTGTGAAGGAAGTGCGTGCTTGGA
CTGTGAAGTCTGGTGCCACCGCGCCGCAGGCCGCTGCGGTGATTCATACGGATTTTGAAAAGGGATTTATCCGTGCCGAA
ACGATTGCTTTCGATGACTTCATTAAATATAAAGGCGAAGCAGGCGCGCGTGATGCTGGGCGTATGCGTTTGGAGGGCAA
GGAGTATCGGGTTCAGGAAGGAGATGTGTTGCATTTTCGCTTTAACGTATGA

Upstream 100 bases:

>100_bases
TGCTTTGGAACGAGCCAGTGTAGTGTTGCCTTTAGCGGTTGCTGGTGACTTTGATGGGGCGATGAAAAAGCTACATACGG
TAGTGTGATGGGAAATCTAT

Downstream 100 bases:

>100_bases
TTCTGTTGCTGCCTAAATGCATTTTTGCCGTATATTTTTTCGATGGTAAGTTTGTTGTAAAGCAGGCTTCTGAATTGGTT
GTGTAGTGGAGTTTTTGTTG

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 362

Protein sequence:

>363_residues
MGIKCGIVGLPNVGKSTLFNALTKAGIAAANFPFCTIEPNVGVVSVPDPRLNQLAEIVKPQKLLPTVIEFVDIAGLVAGA
ASGEGLGNKFLAHIREVDAIAHVVRCFEHGEIIHVAGKVDPLADIEIIDTELILADLDTVEKACNRIMRAAKGGGGEAIA
RKSVLERLQVALNEGKSARSAGLDEDERALVRDLFLLTLKPVMYIANVLENGFQDNVYLEALRVRASSDNAQLVPISAVI
EEELAQLEDVDRDAFLVDLGLEEPGLNRVVRAAYALLGLQTYFTAGVKEVRAWTVKSGATAPQAAAVIHTDFEKGFIRAE
TIAFDDFIKYKGEAGARDAGRMRLEGKEYRVQEGDVLHFRFNV

Sequences:

>Translated_363_residues
MGIKCGIVGLPNVGKSTLFNALTKAGIAAANFPFCTIEPNVGVVSVPDPRLNQLAEIVKPQKLLPTVIEFVDIAGLVAGA
ASGEGLGNKFLAHIREVDAIAHVVRCFEHGEIIHVAGKVDPLADIEIIDTELILADLDTVEKACNRIMRAAKGGGGEAIA
RKSVLERLQVALNEGKSARSAGLDEDERALVRDLFLLTLKPVMYIANVLENGFQDNVYLEALRVRASSDNAQLVPISAVI
EEELAQLEDVDRDAFLVDLGLEEPGLNRVVRAAYALLGLQTYFTAGVKEVRAWTVKSGATAPQAAAVIHTDFEKGFIRAE
TIAFDDFIKYKGEAGARDAGRMRLEGKEYRVQEGDVLHFRFNV
>Mature_362_residues
GIKCGIVGLPNVGKSTLFNALTKAGIAAANFPFCTIEPNVGVVSVPDPRLNQLAEIVKPQKLLPTVIEFVDIAGLVAGAA
SGEGLGNKFLAHIREVDAIAHVVRCFEHGEIIHVAGKVDPLADIEIIDTELILADLDTVEKACNRIMRAAKGGGGEAIAR
KSVLERLQVALNEGKSARSAGLDEDERALVRDLFLLTLKPVMYIANVLENGFQDNVYLEALRVRASSDNAQLVPISAVIE
EELAQLEDVDRDAFLVDLGLEEPGLNRVVRAAYALLGLQTYFTAGVKEVRAWTVKSGATAPQAAAVIHTDFEKGFIRAET
IAFDDFIKYKGEAGARDAGRMRLEGKEYRVQEGDVLHFRFNV

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=368, Percent_Identity=39.945652173913, Blast_Score=278, Evalue=4e-75,
Organism=Homo sapiens, GI58761502, Length=184, Percent_Identity=37.5, Blast_Score=131, Evalue=8e-31,
Organism=Escherichia coli, GI1787454, Length=363, Percent_Identity=65.564738292011, Blast_Score=495, Evalue=1e-141,
Organism=Escherichia coli, GI1789574, Length=127, Percent_Identity=33.8582677165354, Blast_Score=68, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17509631, Length=366, Percent_Identity=39.0710382513661, Blast_Score=276, Evalue=8e-75,
Organism=Saccharomyces cerevisiae, GI6319499, Length=370, Percent_Identity=38.1081081081081, Blast_Score=255, Evalue=9e-69,
Organism=Saccharomyces cerevisiae, GI6321773, Length=383, Percent_Identity=33.6814621409922, Blast_Score=191, Evalue=1e-49,
Organism=Saccharomyces cerevisiae, GI6321649, Length=180, Percent_Identity=37.2222222222222, Blast_Score=91, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24640873, Length=368, Percent_Identity=41.5760869565217, Blast_Score=288, Evalue=5e-78,
Organism=Drosophila melanogaster, GI24640877, Length=368, Percent_Identity=41.5760869565217, Blast_Score=288, Evalue=5e-78,
Organism=Drosophila melanogaster, GI24640875, Length=368, Percent_Identity=41.5760869565217, Blast_Score=288, Evalue=5e-78,
Organism=Drosophila melanogaster, GI24640879, Length=326, Percent_Identity=39.2638036809816, Blast_Score=231, Evalue=5e-61,
Organism=Drosophila melanogaster, GI24585318, Length=157, Percent_Identity=30.5732484076433, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 39243; Mature: 39111

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGIKCGIVGLPNVGKSTLFNALTKAGIAAANFPFCTIEPNVGVVSVPDPRLNQLAEIVKP
CCEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCEEECCCHHHHHHHHHHCC
QKLLPTVIEFVDIAGLVAGAASGEGLGNKFLAHIREVDAIAHVVRCFEHGEIIHVAGKVD
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCC
PLADIEIIDTELILADLDTVEKACNRIMRAAKGGGGEAIARKSVLERLQVALNEGKSARS
CCCCEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHH
AGLDEDERALVRDLFLLTLKPVMYIANVLENGFQDNVYLEALRVRASSDNAQLVPISAVI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHEECCCCCEEEEHHHHH
EEELAQLEDVDRDAFLVDLGLEEPGLNRVVRAAYALLGLQTYFTAGVKEVRAWTVKSGAT
HHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCC
APQAAAVIHTDFEKGFIRAETIAFDDFIKYKGEAGARDAGRMRLEGKEYRVQEGDVLHFR
CCCHHEEEEECHHHCCEEHHHHHHHHHHHHCCCCCCCCCCCEEECCCCEEECCCCEEEEE
FNV
ECC
>Mature Secondary Structure 
GIKCGIVGLPNVGKSTLFNALTKAGIAAANFPFCTIEPNVGVVSVPDPRLNQLAEIVKP
CEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCEEECCCHHHHHHHHHHCC
QKLLPTVIEFVDIAGLVAGAASGEGLGNKFLAHIREVDAIAHVVRCFEHGEIIHVAGKVD
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCC
PLADIEIIDTELILADLDTVEKACNRIMRAAKGGGGEAIARKSVLERLQVALNEGKSARS
CCCCEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHH
AGLDEDERALVRDLFLLTLKPVMYIANVLENGFQDNVYLEALRVRASSDNAQLVPISAVI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHEECCCCCEEEEHHHHH
EEELAQLEDVDRDAFLVDLGLEEPGLNRVVRAAYALLGLQTYFTAGVKEVRAWTVKSGAT
HHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCC
APQAAAVIHTDFEKGFIRAETIAFDDFIKYKGEAGARDAGRMRLEGKEYRVQEGDVLHFR
CCCHHEEEEECHHHCCEEHHHHHHHHHHHHCCCCCCCCCCCEEECCCCEEECCCCEEEEE
FNV
ECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA