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The map label for this gene is estA [H]

Identifier: 182682498

GI number: 182682498

Start: 2224015

End: 2225808

Strand: Direct

Name: estA [H]

Synonym: XfasM23_1985

Alternate gene names: 182682498

Gene position: 2224015-2225808 (Clockwise)

Preceding gene: 182682474

Following gene: 182682507

Centisome position: 87.71

GC content: 54.96

Gene sequence:

>1794_bases
ATGACCTCCAATTTCACACGCTCCCTCCTCGCCTTTGCCATCACGTTGACAACCACACAGGGCATCGCGAAACCAGCCTT
TCAACAAACCATCTTTTTCGGCGACAGCCTGAGTGACAGCGGCTACTACCGCCCGCTCCTACCGAACGAAATACAAGCCA
TCACCGGCAAATTCACCACCAACCCCGGCTGGGTCTGGTCTGAATACGTTGCCAGCTATTATGGAAGCAATGCCTCCCCC
AATGGCAACAGCCAAAGCGGCAACAATTACGCCGCTGGTGGCGCACACATAAATGAACCTTCAATCAGCATATTGGGCGA
AGCACCATCACTAACATCTCAAACGAACGCCTATCTCAGTGCTCATGGGGGCAAGGCTGATCCAAGCGCGCTATACACCC
TCTGGGGTGGCGCTAACGACCTGCTCGACACGTTAACAACTCCAGAACAAATACACACCATCATCGGCAATGCAACCACC
GCAGAAATAAGCCTGGTGAGCACATTGAAAAATGCTGGCGCACATTACATCCTAGTCGCAGCAATCCCTGATCTTGGTTT
GGCACCTCGCGCCCGAAACACAGGGACCACCGCGCAAAGCACTGCTGCGGCCACCGCCTATAACACAACACTATTCACTG
CCCTGAAATCGGCAGGGTTGCAGGTCATCCCGATCGACACCTTCCACTTATTACAGGAATTAATCACCTCACCGGCAACC
TACGGCTTCAGCAACACCACCGACACGGCATGCACCCTACAATTGCCACTGTGCAACCCCACGACCCTGGTCGACGCAAA
TGCACCCAACACCTATGCATTCGCCGATGACATCCACCCAACCACCGCAGCACACCACATGTTGGGCCAGTACGCGATTT
CAATCTTGGAAGCGCCACGGCTCCAGCAAGTGCTGACACGCTCGGCTCAAGGGATCGCCCGCGCCCGCGCCTACCAAGTT
GCCTGGCATCTGGACGGCACACCGCAGCAGGATGGCCTGCACTGGTGGGGCAGCATGCGCAGCGACTCACAGCGCAATGA
CAGTAACGACCTGTACAAAAGCGTTGCACCGGCCGGCCTCTTCGGATTTGACTGGCACAGCGGCCAAATCGTGTCCGGTG
GCTTTATCGGCTACGGACGTATGCATGCCGACTTCAGCAATGGAAACGGCACCTTCAAGCAAAAAGACACCACCTTGGGC
GGCTTTTCAGGCTGGTATACCGGTCCCGTCTGGGTCAATGCCCAAATCAGTTACACCTTGCTGAACTACGACATCAAACG
CGAAGTACAACTCGGTCCAGCCACACGGATACACCGTGGTTCCCCCAATGGCAGCAACCTGACCGTTGCACTGAATGCCA
GTTACGAGATGGGCGAAGGTCGGCTGCGCTATGGCTCAGTGGCTGGACTGACCTGGCAAAAAACCAAATTGGAAAGCTAC
ACCGAACAAAACGCCAGCAGCACCGCGCTGGGTTATGCCGATCAGCAACTCAACTCACTGCTTGGGCGCGTCGGCTTGCA
GATGCGACTGGAAGGAAACGTCGTCACCCCGTACTTACAGGTGACCTACGATCACGAATTCAAGAAACAACAAAACCAAG
CCAATGCATGGCTGCAAACCATGCCAGAAGCGGGTATCTATTCCGTGCCGGGACTGACATTCAATCGCAACTACGCCAGC
ATCGTACTCGGTGCACGCACCAAAATTGGACATCTACAGAGCAACGTTGGCCTCACCACCAGTACAGAGAAGAACGCACG
CGATGTCACGTTATTCGTCAACGGCAATTTTTAA

Upstream 100 bases:

>100_bases
TTCCATCAAGAACAAATTATGAACAATAACCACATACACTACTCAACATACCCATTGGTTGCAGCACCCACCGTCAATTT
TTGAATAAAACACCCTCATC

Downstream 100 bases:

>100_bases
AATACCGCCAGTCTATGCAACAACACACCTTCGAGGTAACCACCGAACTCCCGTCGTTGCCTCCATAGTCAAGGAAGCAT
AGACTGCCGGGCGTACCGCA

Product: outer membrane autotransporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 597; Mature: 596

Protein sequence:

>597_residues
MTSNFTRSLLAFAITLTTTQGIAKPAFQQTIFFGDSLSDSGYYRPLLPNEIQAITGKFTTNPGWVWSEYVASYYGSNASP
NGNSQSGNNYAAGGAHINEPSISILGEAPSLTSQTNAYLSAHGGKADPSALYTLWGGANDLLDTLTTPEQIHTIIGNATT
AEISLVSTLKNAGAHYILVAAIPDLGLAPRARNTGTTAQSTAAATAYNTTLFTALKSAGLQVIPIDTFHLLQELITSPAT
YGFSNTTDTACTLQLPLCNPTTLVDANAPNTYAFADDIHPTTAAHHMLGQYAISILEAPRLQQVLTRSAQGIARARAYQV
AWHLDGTPQQDGLHWWGSMRSDSQRNDSNDLYKSVAPAGLFGFDWHSGQIVSGGFIGYGRMHADFSNGNGTFKQKDTTLG
GFSGWYTGPVWVNAQISYTLLNYDIKREVQLGPATRIHRGSPNGSNLTVALNASYEMGEGRLRYGSVAGLTWQKTKLESY
TEQNASSTALGYADQQLNSLLGRVGLQMRLEGNVVTPYLQVTYDHEFKKQQNQANAWLQTMPEAGIYSVPGLTFNRNYAS
IVLGARTKIGHLQSNVGLTTSTEKNARDVTLFVNGNF

Sequences:

>Translated_597_residues
MTSNFTRSLLAFAITLTTTQGIAKPAFQQTIFFGDSLSDSGYYRPLLPNEIQAITGKFTTNPGWVWSEYVASYYGSNASP
NGNSQSGNNYAAGGAHINEPSISILGEAPSLTSQTNAYLSAHGGKADPSALYTLWGGANDLLDTLTTPEQIHTIIGNATT
AEISLVSTLKNAGAHYILVAAIPDLGLAPRARNTGTTAQSTAAATAYNTTLFTALKSAGLQVIPIDTFHLLQELITSPAT
YGFSNTTDTACTLQLPLCNPTTLVDANAPNTYAFADDIHPTTAAHHMLGQYAISILEAPRLQQVLTRSAQGIARARAYQV
AWHLDGTPQQDGLHWWGSMRSDSQRNDSNDLYKSVAPAGLFGFDWHSGQIVSGGFIGYGRMHADFSNGNGTFKQKDTTLG
GFSGWYTGPVWVNAQISYTLLNYDIKREVQLGPATRIHRGSPNGSNLTVALNASYEMGEGRLRYGSVAGLTWQKTKLESY
TEQNASSTALGYADQQLNSLLGRVGLQMRLEGNVVTPYLQVTYDHEFKKQQNQANAWLQTMPEAGIYSVPGLTFNRNYAS
IVLGARTKIGHLQSNVGLTTSTEKNARDVTLFVNGNF
>Mature_596_residues
TSNFTRSLLAFAITLTTTQGIAKPAFQQTIFFGDSLSDSGYYRPLLPNEIQAITGKFTTNPGWVWSEYVASYYGSNASPN
GNSQSGNNYAAGGAHINEPSISILGEAPSLTSQTNAYLSAHGGKADPSALYTLWGGANDLLDTLTTPEQIHTIIGNATTA
EISLVSTLKNAGAHYILVAAIPDLGLAPRARNTGTTAQSTAAATAYNTTLFTALKSAGLQVIPIDTFHLLQELITSPATY
GFSNTTDTACTLQLPLCNPTTLVDANAPNTYAFADDIHPTTAAHHMLGQYAISILEAPRLQQVLTRSAQGIARARAYQVA
WHLDGTPQQDGLHWWGSMRSDSQRNDSNDLYKSVAPAGLFGFDWHSGQIVSGGFIGYGRMHADFSNGNGTFKQKDTTLGG
FSGWYTGPVWVNAQISYTLLNYDIKREVQLGPATRIHRGSPNGSNLTVALNASYEMGEGRLRYGSVAGLTWQKTKLESYT
EQNASSTALGYADQQLNSLLGRVGLQMRLEGNVVTPYLQVTYDHEFKKQQNQANAWLQTMPEAGIYSVPGLTFNRNYASI
VLGARTKIGHLQSNVGLTTSTEKNARDVTLFVNGNF

Specific function: Unknown

COG id: COG3240

COG function: function code IR; Phospholipase/lecithinase/hemolysin

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 autotransporter (TC 1.B.12) domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005546
- InterPro:   IPR013830
- InterPro:   IPR013831
- InterPro:   IPR017186
- InterPro:   IPR001087
- InterPro:   IPR008265
- InterPro:   IPR006315 [H]

Pfam domain/function: PF03797 Autotransporter; PF00657 Lipase_GDSL [H]

EC number: =3.1.1.1 [H]

Molecular weight: Translated: 64345; Mature: 64214

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSNFTRSLLAFAITLTTTQGIAKPAFQQTIFFGDSLSDSGYYRPLLPNEIQAITGKFTT
CCCHHHHHHHHHEEEEECCCCCCCHHHHHEEEECCCCCCCCCCCCCCCCCHHHEECEEEC
NPGWVWSEYVASYYGSNASPNGNSQSGNNYAAGGAHINEPSISILGEAPSLTSQTNAYLS
CCCCHHHHHHHHHHCCCCCCCCCCCCCCCEECCCCEECCCCEEEEECCCCCCCCCCEEEE
AHGGKADPSALYTLWGGANDLLDTLTTPEQIHTIIGNATTAEISLVSTLKNAGAHYILVA
ECCCCCCCCEEEEEECCCHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEEE
AIPDLGLAPRARNTGTTAQSTAAATAYNTTLFTALKSAGLQVIPIDTFHLLQELITSPAT
ECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHCCCCC
YGFSNTTDTACTLQLPLCNPTTLVDANAPNTYAFADDIHPTTAAHHMLGQYAISILEAPR
CCCCCCCCCEEEEEEECCCCCEEEECCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCHH
LQQVLTRSAQGIARARAYQVAWHLDGTPQQDGLHWWGSMRSDSQRNDSNDLYKSVAPAGL
HHHHHHHHHHHHHHHEEEEEEEEECCCCCCCCCEEECCCCCCCCCCCCHHHHHHHCCCCE
FGFDWHSGQIVSGGFIGYGRMHADFSNGNGTFKQKDTTLGGFSGWYTGPVWVNAQISYTL
EEEECCCCEEEECCEEEECEEEEEECCCCCCEEECCCCCCCCCCCCCCCEEEEEEEEEEE
LNYDIKREVQLGPATRIHRGSPNGSNLTVALNASYEMGEGRLRYGSVAGLTWQKTKLESY
EEECEEEEEECCCCCEEECCCCCCCEEEEEEECCEECCCCEEEECEEECCEEEHHHHHHH
TEQNASSTALGYADQQLNSLLGRVGLQMRLEGNVVTPYLQVTYDHEFKKQQNQANAWLQT
HHCCCCCCEECCHHHHHHHHHHHCCEEEEECCCEECCEEEEEECCHHHHHHHHHHHHHHH
MPEAGIYSVPGLTFNRNYASIVLGARTKIGHLQSNVGLTTSTEKNARDVTLFVNGNF
CCCCCCEECCCEEECCCEEEEEEECCCHHHHHHCCCCCEECCCCCCCEEEEEEECCC
>Mature Secondary Structure 
TSNFTRSLLAFAITLTTTQGIAKPAFQQTIFFGDSLSDSGYYRPLLPNEIQAITGKFTT
CCHHHHHHHHHEEEEECCCCCCCHHHHHEEEECCCCCCCCCCCCCCCCCHHHEECEEEC
NPGWVWSEYVASYYGSNASPNGNSQSGNNYAAGGAHINEPSISILGEAPSLTSQTNAYLS
CCCCHHHHHHHHHHCCCCCCCCCCCCCCCEECCCCEECCCCEEEEECCCCCCCCCCEEEE
AHGGKADPSALYTLWGGANDLLDTLTTPEQIHTIIGNATTAEISLVSTLKNAGAHYILVA
ECCCCCCCCEEEEEECCCHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEEE
AIPDLGLAPRARNTGTTAQSTAAATAYNTTLFTALKSAGLQVIPIDTFHLLQELITSPAT
ECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHCCCCC
YGFSNTTDTACTLQLPLCNPTTLVDANAPNTYAFADDIHPTTAAHHMLGQYAISILEAPR
CCCCCCCCCEEEEEEECCCCCEEEECCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCHH
LQQVLTRSAQGIARARAYQVAWHLDGTPQQDGLHWWGSMRSDSQRNDSNDLYKSVAPAGL
HHHHHHHHHHHHHHHEEEEEEEEECCCCCCCCCEEECCCCCCCCCCCCHHHHHHHCCCCE
FGFDWHSGQIVSGGFIGYGRMHADFSNGNGTFKQKDTTLGGFSGWYTGPVWVNAQISYTL
EEEECCCCEEEECCEEEECEEEEEECCCCCCEEECCCCCCCCCCCCCCCEEEEEEEEEEE
LNYDIKREVQLGPATRIHRGSPNGSNLTVALNASYEMGEGRLRYGSVAGLTWQKTKLESY
EEECEEEEEECCCCCEEECCCCCCCEEEEEEECCEECCCCEEEECEEECCEEEHHHHHHH
TEQNASSTALGYADQQLNSLLGRVGLQMRLEGNVVTPYLQVTYDHEFKKQQNQANAWLQT
HHCCCCCCEECCHHHHHHHHHHHCCEEEEECCCEECCEEEEEECCHHHHHHHHHHHHHHH
MPEAGIYSVPGLTFNRNYASIVLGARTKIGHLQSNVGLTTSTEKNARDVTLFVNGNF
CCCCCCEECCCEEECCCEEEEEEECCCHHHHHHCCCCCEECCCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10559163; 10984043 [H]