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The map label for this gene is ribH

Identifier: 182682360

GI number: 182682360

Start: 2046609

End: 2047073

Strand: Reverse

Name: ribH

Synonym: XfasM23_1845

Alternate gene names: 182682360

Gene position: 2047073-2046609 (Counterclockwise)

Preceding gene: 182682361

Following gene: 182682359

Centisome position: 80.73

GC content: 55.05

Gene sequence:

>465_bases
ATGAGCCACTACGAAGGCGATCTTCGCCCCGCAGGTGCGCGCTTTGTGATCGTCTGCAGCCGCTGGAACGCTCGTATTAC
TGATGCATTAGTTGCTGGTGCCTGTCACAGTCTTGTTGACAATGGTGTACCAGATGACGCAGTGGATGTGGTGCGTGTGC
CGGGTGCATGGGAGATCCCTATCGTTGCCAATCTGCTTGCGCAGGCAGGGCAACATGCCGCCATCATTGCATTGGGGTGT
GTGGTTCGTGGCGATACCCGTCATTACGAGCATGTCGCCGATCTATGTGCTGAGGGAATGATGAGTGTGCAGATGCAGAC
GGGTGTCCCTGTACTGAATGGTGTGCTTGCTGTCGAGTGCATTAAAGATGCCGAGATGCGTGCTGGTGGGAGTCATGGTA
ACAAGGGGGCGGAAACTGCCTTGGCGGCTTTGGAAATGGTGAGTTTGTTGGAGAAGTTGCCATGA

Upstream 100 bases:

>100_bases
TGGTCTGGAAGTGCTAGAGTATGTGGAATGCCGCGGCGGGGTCCCGGTCCCCTCCCAGGGTGTCGATTGAATTTTTCCTC
ATTCCGGAGTCAAACCTTAG

Downstream 100 bases:

>100_bases
GCAAGGTTTCCGGTGGCGGACCGTGTTCGAGACGCCGGGATGGTGTTGATCCAGCGCTGCGTTCACGTGCGCGCCGTCGT
GCTTTGCAAGCGGTGTACGC

Product: 6,7-dimethyl-8-ribityllumazine synthase

Products: NA

Alternate protein names: DMRL synthase; Lumazine synthase; Riboflavin synthase beta chain

Number of amino acids: Translated: 154; Mature: 153

Protein sequence:

>154_residues
MSHYEGDLRPAGARFVIVCSRWNARITDALVAGACHSLVDNGVPDDAVDVVRVPGAWEIPIVANLLAQAGQHAAIIALGC
VVRGDTRHYEHVADLCAEGMMSVQMQTGVPVLNGVLAVECIKDAEMRAGGSHGNKGAETALAALEMVSLLEKLP

Sequences:

>Translated_154_residues
MSHYEGDLRPAGARFVIVCSRWNARITDALVAGACHSLVDNGVPDDAVDVVRVPGAWEIPIVANLLAQAGQHAAIIALGC
VVRGDTRHYEHVADLCAEGMMSVQMQTGVPVLNGVLAVECIKDAEMRAGGSHGNKGAETALAALEMVSLLEKLP
>Mature_153_residues
SHYEGDLRPAGARFVIVCSRWNARITDALVAGACHSLVDNGVPDDAVDVVRVPGAWEIPIVANLLAQAGQHAAIIALGCV
VRGDTRHYEHVADLCAEGMMSVQMQTGVPVLNGVLAVECIKDAEMRAGGSHGNKGAETALAALEMVSLLEKLP

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes

COG id: COG0054

COG function: function code H; Riboflavin synthase beta-chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DMRL synthase family

Homologues:

Organism=Escherichia coli, GI1786617, Length=154, Percent_Identity=43.5064935064935, Blast_Score=122, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6324429, Length=142, Percent_Identity=31.6901408450704, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RISB_XYLF2 (B2I8Q5)

Other databases:

- EMBL:   CP001011
- RefSeq:   YP_001830520.1
- ProteinModelPortal:   B2I8Q5
- SMR:   B2I8Q5
- GeneID:   6203104
- GenomeReviews:   CP001011_GR
- KEGG:   xfn:XfasM23_1845
- HOGENOM:   HBG311126
- OMA:   KAGNKGW
- ProtClustDB:   PRK00061
- HAMAP:   MF_00178
- InterPro:   IPR002180
- Gene3D:   G3DSA:3.40.50.960
- PANTHER:   PTHR21058
- TIGRFAMs:   TIGR00114

Pfam domain/function: PF00885 DMRL_synthase; SSF52121 DMRL_synthase

EC number: =2.5.1.9

Molecular weight: Translated: 16165; Mature: 16034

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHYEGDLRPAGARFVIVCSRWNARITDALVAGACHSLVDNGVPDDAVDVVRVPGAWEIP
CCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCHHEEECCCCCCHH
IVANLLAQAGQHAAIIALGCVVRGDTRHYEHVADLCAEGMMSVQMQTGVPVLNGVLAVEC
HHHHHHHHCCCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
IKDAEMRAGGSHGNKGAETALAALEMVSLLEKLP
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SHYEGDLRPAGARFVIVCSRWNARITDALVAGACHSLVDNGVPDDAVDVVRVPGAWEIP
CCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCHHEEECCCCCCHH
IVANLLAQAGQHAAIIALGCVVRGDTRHYEHVADLCAEGMMSVQMQTGVPVLNGVLAVEC
HHHHHHHHCCCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
IKDAEMRAGGSHGNKGAETALAALEMVSLLEKLP
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA